X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (5798) 5798
Publication (820) 820
Book Review (47) 47
Book Chapter (24) 24
Dissertation (13) 13
Conference Proceeding (6) 6
Government Document (4) 4
Book / eBook (2) 2
Magazine Article (2) 2
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (3487) 3487
humans (3462) 3462
index medicus (3338) 3338
mice (1832) 1832
male (1612) 1612
hepatocytes (1341) 1341
liver (1150) 1150
expression (1133) 1133
hepatocyte growth-factor (1127) 1127
rats (1082) 1082
cell biology (1067) 1067
oncology (1028) 1028
hepatocytes - metabolism (1026) 1026
female (983) 983
cells, cultured (972) 972
signal transduction (957) 957
biochemistry & molecular biology (926) 926
apoptosis (868) 868
cell line, tumor (820) 820
hepatocytes - drug effects (768) 768
gene expression (727) 727
cancer (713) 713
gastroenterology & hepatology (681) 681
activation (666) 666
rodents (652) 652
proteins (645) 645
phosphorylation (636) 636
hepatocyte growth factor (619) 619
hepatocyte growth factor - metabolism (593) 593
liver - metabolism (591) 591
research (591) 591
cell line (576) 576
c-met (571) 571
article (567) 567
signal transduction - drug effects (554) 554
proto-oncogene proteins c-met - metabolism (533) 533
cells (513) 513
multidisciplinary sciences (499) 499
cell proliferation (486) 486
mice, inbred c57bl (484) 484
kinases (473) 473
gene-expression (459) 459
hepatocyte growth factor - pharmacology (456) 456
pharmacology & pharmacy (444) 444
liver diseases (438) 438
research article (430) 430
analysis (428) 428
medicine (425) 425
apoptosis - drug effects (419) 419
health aspects (419) 419
physiological aspects (417) 417
hepatocytes - cytology (410) 410
inflammation (409) 409
in-vitro (408) 408
growth factors (406) 406
medicine, research & experimental (400) 400
proto-oncogene proteins c-met - antagonists & inhibitors (396) 396
cell proliferation - drug effects (389) 389
enzyme inhibitors - pharmacology (376) 376
stem cells (375) 375
fibrosis (373) 373
liver - drug effects (366) 366
metastasis (365) 365
inhibition (362) 362
receptor (352) 352
tumors (351) 351
in-vivo (345) 345
physiology (344) 344
science (340) 340
metabolism (337) 337
middle aged (333) 333
liver - pathology (331) 331
genetic aspects (327) 327
hepatocytes - pathology (325) 325
liver cancer (324) 324
proliferation (322) 322
hepatocyte growth factor - genetics (321) 321
angiogenesis (319) 319
oxidative stress (315) 315
cytokines (309) 309
dose-response relationship, drug (307) 307
rats, wistar (305) 305
rna, messenger - metabolism (301) 301
rats, sprague-dawley (296) 296
biology (292) 292
blotting, western (291) 291
mice, knockout (291) 291
disease models, animal (287) 287
adult (284) 284
care and treatment (274) 274
growth (271) 271
tumor cells, cultured (270) 270
antineoplastic agents - pharmacology (267) 267
proto-oncogene proteins c-met - genetics (266) 266
differentiation (264) 264
hgf (261) 261
protein kinase inhibitors - pharmacology (260) 260
transfection (259) 259
immunology (258) 258
time factors (256) 256
more...
Library Location Library Location
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


PLoS ONE, ISSN 1932-6203, 08/2014, Volume 9, Issue 8, p. e106071
Metastasis is one of the major causes of cancer-related death. It is a complex biological process involving multiple genes, steps, and phases. It is also... 
IN-VITRO | ANGIOGENESIS | VEGF | MULTIDISCIPLINARY SCIENCES | LYMPHANGIOGENESIS | ANTICOAGULANT | PROLIFERATION | SMMC-7721 CELLS | METALLOPROTEINASES | EXPRESSION | ANTITUMOR | Male | NF-kappa B - metabolism | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Vascular Endothelial Growth Factor A - genetics | Carcinoma, Hepatocellular - drug therapy | Hepatocyte Growth Factor - antagonists & inhibitors | Hepatocyte Growth Factor - genetics | Cyclin-Dependent Kinase 4 - antagonists & inhibitors | NF-kappa B - antagonists & inhibitors | Proto-Oncogene Proteins c-met - antagonists & inhibitors | Lymphatic Metastasis | Undaria - chemistry | Cell Adhesion - drug effects | Cyclin-Dependent Kinase 4 - metabolism | Hepatocyte Growth Factor - metabolism | Cell Movement - drug effects | Cyclin D1 - genetics | Cell Line, Tumor | Mice | Carcinoma, Hepatocellular - metabolism | Proto-Oncogene Proteins c-met - metabolism | Cyclin D1 - metabolism | Plant Extracts - chemistry | Cyclin-Dependent Kinase 4 - genetics | Gene Expression Regulation, Neoplastic | Phosphatidylinositol 3-Kinases - metabolism | MAP Kinase Signaling System | Dose-Response Relationship, Drug | Liver Neoplasms, Experimental - metabolism | Cyclin D1 - antagonists & inhibitors | Receptors, Vascular Endothelial Growth Factor - metabolism | Polysaccharides - isolation & purification | Carcinoma, Hepatocellular - genetics | Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors | Liver Neoplasms, Experimental - genetics | Receptors, Vascular Endothelial Growth Factor - genetics | Liver Neoplasms, Experimental - pathology | Polysaccharides - pharmacology | Proto-Oncogene Proteins c-met - genetics | Phosphatidylinositol 3-Kinases - genetics | Animals | Liver Neoplasms, Experimental - drug therapy | NF-kappa B - genetics | Carcinoma, Hepatocellular - pathology | Cell Proliferation - drug effects | Antineoplastic Agents, Phytogenic - pharmacology | Antineoplastic Agents, Phytogenic - isolation & purification | Metastasis | Sulfates | Vascular endothelial growth factor | Health aspects | Biotechnology | Tissue inhibitor of metalloproteinases | Brain cancer | AKT protein | Kinases | Cyclin D1 | Inactivation | Cyclin-dependent kinase 4 | Molecular weight | Cell adhesion & migration | Sulfuric acid | Metastases | c-Met protein | Cyclin-dependent kinase | Angiogenesis | Signal transduction | Cell growth | Cell cycle | L-selectin | Physiology | Inhibition | Anticoagulants | Medical research | NF-κB protein | Lymphatic system | Deactivation | Hepatocyte growth factor | Invasiveness | Extracellular signal-regulated kinase | Breast cancer | Fucoidan | Adhesion | Chromatography | Biological activity | 1-Phosphatidylinositol 3-kinase | Signaling | Cell migration | Cancer | Apoptosis
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 2014, Volume 15, Issue 8, pp. 13768 - 13801
Chemotherapeutic and cytotoxic drugs are widely used in the treatment of cancer. In spite of the improvements in the life quality of patients, their... 
Small-molecule inhibitors | Targeted cancer therapy | Receptor tyrosine kinases | Tyrosine kinase inhibitors | targeted cancer therapy | PAN-ERBB INHIBITOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACUTE MYELOGENOUS LEUKEMIA | HEPATOCYTE GROWTH-FACTOR | ACUTE MYELOID-LEUKEMIA | ANTITUMOR-ACTIVITY | CHEMISTRY, MULTIDISCIPLINARY | tyrosine kinase inhibitors | CELL LUNG-CANCER | PHASE-II TRIAL | receptor tyrosine kinases | CHRONIC LYMPHOCYTIC-LEUKEMIA | TUMOR-GROWTH | C-MET INHIBITOR | small-molecule inhibitors | fms-Like Tyrosine Kinase 3 - antagonists & inhibitors | Receptors, Platelet-Derived Growth Factor - antagonists & inhibitors | Humans | Receptors, Fibroblast Growth Factor - antagonists & inhibitors | Small Molecule Libraries - therapeutic use | Drug Resistance, Neoplasm | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - chemistry | Receptor Protein-Tyrosine Kinases - metabolism | fms-Like Tyrosine Kinase 3 - metabolism | Neoplasms - drug therapy | Small Molecule Libraries - chemistry | Protein Kinase Inhibitors - chemistry | Receptor, Epidermal Growth Factor - metabolism | Receptors, Vascular Endothelial Growth Factor - metabolism | Protein Kinase Inhibitors - therapeutic use | Receptors, Platelet-Derived Growth Factor - metabolism | Receptors, Fibroblast Growth Factor - metabolism | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors | Pharmacology | Inhibitor drugs | Kinases | Cancer
Journal Article
Cancer Cell, ISSN 1535-6108, 2008, Volume 14, Issue 5, pp. 382 - 393
A key step in angiogenesis is the upregulation of growth factor receptors on endothelial cells. Here, we demonstrate that a small regulatory microRNA, miR-296,... 
CELLCYCLE | THERAPY | ONCOLOGY | VASCULAR INTEGRITY | IN-VIVO | GENE-EXPRESSION | DEGRADATION | TARGETS | OCULAR NEOVASCULARIZATION | TUMOR ANGIOGENESIS | MICRORNAS | CANCER | CELL BIOLOGY | Endothelium, Vascular - cytology | Luciferases - metabolism | MicroRNAs - antagonists & inhibitors | Humans | Neovascularization, Pathologic | Molecular Sequence Data | MicroRNAs - metabolism | Brain Neoplasms - blood supply | Phosphoproteins - antagonists & inhibitors | Phosphoproteins - metabolism | RNA, Messenger - metabolism | Receptor, Platelet-Derived Growth Factor beta - genetics | Brain Neoplasms - metabolism | Glioma - metabolism | Vascular Endothelial Growth Factor Receptor-2 - genetics | Vascular Endothelial Growth Factor Receptor-2 - antagonists & inhibitors | Kidney - metabolism | Receptor, Platelet-Derived Growth Factor beta - antagonists & inhibitors | Oligonucleotides - pharmacology | Base Sequence | RNA, Messenger - antagonists & inhibitors | Glioma - therapy | Umbilical Veins - cytology | Receptor, Platelet-Derived Growth Factor beta - metabolism | Signal Transduction | Endosomal Sorting Complexes Required for Transport | RNA, Messenger - genetics | RNA, Small Interfering - pharmacology | Cells, Cultured | Angiogenesis Inhibitors - pharmacology | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Kidney - cytology | Phosphoproteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Sequence Homology, Nucleic Acid | Blotting, Western | Hepatocyte Growth Factor - metabolism | Glioma - blood supply | Xenograft Model Antitumor Assays | Magnetic Resonance Imaging | Animals | Endothelium, Vascular - metabolism | Brain Neoplasms - therapy | Fluorescent Antibody Technique | Mice | MicroRNAs - genetics | Cell Movement | Umbilical Veins - metabolism | Tyrosine | Medical colleges | Neurosciences | Messenger RNA | Gliomas | Oncology, Experimental | Brain tumors | Research | Growth factors | Cancer | Endothelium | PDGFR | VEGFR | miRNA | cancer | HGS | angiogenesis
Journal Article
International Journal of Cancer, ISSN 0020-7136, 05/2010, Volume 126, Issue 10, pp. 2426 - 2436
Hepatocellular carcinoma (HCC) is the 5th most common cancer worldwide. It is intrinsically resistant toward standard chemotherapy, making it imperative to... 
β‐catenin | Wnt signaling | hepatocellular carcinoma | β-catenin | Hepatocellular carcinoma | beta-catenin | METASTASIS | MOUSE | C-MYC | ALPHA | HUMAN HEPATOCELLULAR CARCINOMAS | BETA-CATENIN MUTATIONS | COLON-CANCER | ONCOLOGY | RECURRENCE | EXPRESSION | Writ signaling | PROGRESSION | Cyclin D1 - drug effects | Immunohistochemistry | Apoptosis - drug effects | Humans | Microtubule-Associated Proteins - drug effects | Hepatocytes - metabolism | Wnt Proteins - metabolism | Transcription Factors - drug effects | Dose-Response Relationship, Drug | Carcinoma, Hepatocellular - drug therapy | beta Catenin - drug effects | Pyrimidinones - pharmacology | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Genes, myc - drug effects | Hepatocytes - drug effects | Perylene - analogs & derivatives | Triazines - pharmacology | Transcription Factor 4 | Inhibitor of Apoptosis Proteins | Liver Neoplasms - drug therapy | Random Allocation | Down-Regulation - drug effects | beta Catenin - metabolism | Blotting, Western | Perylene - pharmacology | Transcription Factors - metabolism | Xenograft Model Antitumor Assays | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - drug effects | Animals | Signal Transduction - drug effects | Mice, Nude | Liver Neoplasms - metabolism | Cell Line, Tumor | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Mice | Carcinoma, Hepatocellular - metabolism | Drug Screening Assays, Antitumor | Index Medicus
Journal Article
Cancer Science, ISSN 1347-9032, 03/2017, Volume 108, Issue 3, pp. 296 - 307
Signaling driven by hepatocyte growth factor (HGF) and MET receptor facilitates conspicuous biological responses such as epithelial cell migration, 3‐D... 
Biomarker | receptor tyrosine kinase | drug resistance | MET | HGF | C-MET RECEPTOR | GEFITINIB RESISTANCE | SOMATIC MUTATIONS | CELL LUNG-CANCER | TYROSINE KINASE INHIBITORS | BREAST-CANCER | ONCOLOGY | GASTRIC-CANCER | COLORECTAL-CANCER | MOLECULAR-CLONING | MET/HGF RECEPTOR | Proto-Oncogene Proteins c-met - metabolism | Signal Transduction | Cell Survival | Proto-Oncogene Proteins c-met - antagonists & inhibitors | Humans | Tumor Microenvironment | Epithelial Cells - pathology | Hepatocyte Growth Factor - metabolism | Proto-Oncogene Proteins c-met - genetics | Drug Resistance, Neoplasm - genetics | Hepatocyte Growth Factor - antagonists & inhibitors | Neoplasm Metastasis - pathology | Biomarkers, Tumor - metabolism | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Biomarkers, Tumor - genetics | Enzyme Activation | Neoplasms - pathology | Cell Movement | Phosphorylation | Leukocyte migration | Laboratories | Epithelial cells | Lung cancer | Clinical trials | Paracrine signalling | Raf protein | Metastasis | Drug resistance | Exosomes | Kinases | Cancer therapies | Regulatory approval | Metastases | c-Met protein | Proteins | Morphogenesis | Signal transduction | Colon cancer | Epidermal growth factor | Fibroblasts | Bone marrow | Protein-tyrosine kinase receptors | Autocrine signalling | Gastric cancer | Medical research | Cell survival | Hepatocyte growth factor | Research & development--R&D | Melanoma | Lymphoma | Patients | Gene amplification | Collagen | Biomarkers | Mutation | Cell migration | Review
Journal Article
Biology of Reproduction, ISSN 0006-3363, 2013, Volume 89, Issue 4, p. 81
The prostate gland is unique in that it undergoes rapid regression following castration but regenerates completely once androgens are replaced. Residual ductal... 
Basal epithelial cells | Fibroblast growth factor 2 | Castration | Organ culture | Fibroblast growth factor receptor | Prostate | Growth factor | ANDROGEN RECEPTOR | METABOLIC SYNDROME | TESTOSTERONE | castration | FIBROBLAST-GROWTH-FACTOR | HYPERPLASIA | CANCER STEM-CELLS | growth factor | REPRODUCTIVE BIOLOGY | fibroblast growth factor receptor | fibroblast growth factor 2 | RAT VENTRAL PROSTATE | organ culture | IN-VIVO | basal epithelial cells | prostate | DIFFERENTIATION | EXPRESSION | Castration - adverse effects | Transforming Growth Factors - genetics | Basement Membrane - drug effects | Receptor, Fibroblast Growth Factor, Type 2 - metabolism | Epithelial Cells - drug effects | Male | Hormone Replacement Therapy | Epithelial Cells - physiology | Receptor, Fibroblast Growth Factor, Type 2 - agonists | Fibroblast Growth Factor 7 - metabolism | Hepatocyte Growth Factor - antagonists & inhibitors | Fibroblast Growth Factor 2 - metabolism | Hepatocyte Growth Factor - genetics | Prostate - drug effects | Androgens - therapeutic use | Receptor, Fibroblast Growth Factor, Type 2 - antagonists & inhibitors | Prostate - physiology | Epithelial Cells - cytology | Organ Culture Techniques | Recombinant Proteins - metabolism | Basement Membrane - cytology | Mice, Inbred C57BL | Fibroblast Growth Factor 7 - antagonists & inhibitors | Transforming Growth Factors - antagonists & inhibitors | Fibroblast Growth Factor 7 - genetics | Transforming Growth Factors - metabolism | Hepatocyte Growth Factor - metabolism | Gene Expression Regulation - drug effects | Fibroblast Growth Factor 2 - antagonists & inhibitors | Regeneration - drug effects | Animals | Androgens - pharmacology | Fibroblast Growth Factor 2 - genetics | Signal Transduction - drug effects | Prostate - cytology | Basement Membrane - physiology | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 08/2013, Volume 110, Issue 32, pp. E2987 - E2996
Binding of hepatocyte growth factor (HGF) to the receptor tyrosine kinase MET is implicated in the malignant process of multiple cancers, making disruption of... 
MetMAb | HGFR | OA5D5 | Scatter factor | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | HEPATOCYTE GROWTH-FACTOR | PHARMACOKINETIC PK | DOSE-ESCALATION | SINGLE-AGENT | scatter factor | C-MET | BINDING-SITE | RECEPTOR MET | MONOCLONAL-ANTIBODIES | Proto-Oncogene Proteins c-met - metabolism | Humans | Molecular Sequence Data | Crystallography, X-Ray | Hepatocyte Growth Factor - pharmacology | Antibodies, Monoclonal, Humanized - genetics | Antibodies, Monoclonal, Humanized - pharmacology | Protein Binding - drug effects | Drug Design | Antineoplastic Agents - pharmacology | Hepatocyte Growth Factor - chemistry | Antibodies, Monoclonal - chemistry | Protein Structure, Tertiary | Amino Acid Sequence | Immunoglobulin Fab Fragments - genetics | Proto-Oncogene Proteins c-met - antagonists & inhibitors | Antibodies, Monoclonal - pharmacology | Models, Molecular | Mice, Transgenic | Antineoplastic Agents - chemistry | Mice, SCID | Immunoglobulin Fab Fragments - pharmacology | Mice, Inbred C3H | Hepatocyte Growth Factor - metabolism | Neoplasms - drug therapy | Sequence Homology, Amino Acid | Xenograft Model Antitumor Assays | Antibodies, Monoclonal - genetics | Animals | Mice, Nude | Immunoglobulin Fab Fragments - chemistry | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Antibodies, Monoclonal - metabolism | Proto-Oncogene Proteins c-met - chemistry | Neoplasms - pathology | Antibodies, Monoclonal, Humanized - chemistry | Biological Sciences | PNAS Plus
Journal Article
Cancer Science, ISSN 1347-9032, 06/2014, Volume 105, Issue 6, pp. 723 - 730
Vascular endothelial growth factor receptor (VEGFR) inhibitors are approved for the treatment of several tumor types; however, some tumors show intrinsic... 
Angiogenesis | vascular endothelial growth factor receptor | Met | resistance | hepatocyte growth factor signaling | Resistance | Vascular endothelial growth factor receptor | Hepatocyte growth factor signaling | SURVIVAL | ACTIVATION | METASTASIS | CANCER CELLS | KINASE | ONCOLOGY | MET SIGNALING PATHWAY | C-MET | IN-VIVO | TUMOR-GROWTH | Human Umbilical Vein Endothelial Cells - drug effects | Proto-Oncogene Proteins c-met - antagonists & inhibitors | Vascular Endothelial Growth Factor Receptor-2 - pharmacology | Humans | Drug Resistance, Neoplasm | Hepatocyte Growth Factor - pharmacology | Piperazines - pharmacology | Quinolines - pharmacology | Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Vascular Endothelial Growth Factor Receptor-2 - antagonists & inhibitors | Animals | Hepatocyte Growth Factor - antagonists & inhibitors | Signal Transduction - drug effects | Mice, Nude | Neovascularization, Pathologic - drug therapy | Aminopyridines - pharmacology | Cell Line, Tumor | Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors | Female | Cell Proliferation - drug effects | Mice | Phenylurea Compounds - pharmacology | Hepatocyte growth factor | Tumor cells | Lung cancer | Melanoma | Clinical trials | Metastasis | Tumor cell lines | Kinases | Cancer therapies | Molecular weight | Endothelial cells | Vascular endothelial growth factor receptors | c-Met protein | Signal transduction | Epidermal growth factor | Medical prognosis | Cooperation | Xenografts | Fibroblasts | Antitumor activity | Lymphomas | Vascular endothelial growth factor | Tumors | Original
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 2014, Volume 350, Issue 3, pp. 563 - 577
Journal Article