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Journal of Cellular Physiology, ISSN 0021-9541, 09/2007, Volume 212, Issue 3, pp. 702 - 709
Adipose tissue serves as a source of adipokines and cytokines with both local and systemic actions in health and disease. In this study, we examine the... 
BREAST-CANCER | TUMOR-NECROSIS-FACTOR | IN-VITRO | PHYSIOLOGY | TEMPORAL-CHANGES | MURINE BONE-MARROW | INSULIN-RESISTANCE | HEPATOCYTE GROWTH-FACTOR | ENDOTHELIAL-CELLS | TISSUE | STROMAL CELLS | CELL BIOLOGY | Tumor Necrosis Factor-alpha - metabolism | Angiogenic Proteins - genetics | Cell Proliferation | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Coculture Techniques | Humans | Middle Aged | Multipotent Stem Cells - metabolism | Adipose Tissue - cytology | RNA, Messenger - metabolism | Hematopoiesis - drug effects | Adipose Tissue - metabolism | Multipotent Stem Cells - drug effects | Time Factors | Inflammation Mediators - metabolism | Fibroblast Growth Factor 2 - metabolism | Adult | Female | Cell Differentiation | Interleukin-8 - metabolism | Cytokines - genetics | Interleukin-6 - metabolism | Granulocyte Colony-Stimulating Factor - metabolism | Interleukin-7 - metabolism | Adult Stem Cells - drug effects | Adult Stem Cells - cytology | Cytokines - metabolism | Paracrine Communication | Endothelial Cells - metabolism | Ascorbic Acid - analogs & derivatives | Cells, Cultured | Epidermal Growth Factor - metabolism | Interleukin-11 - metabolism | Hematopoietic Stem Cells - metabolism | Hepatocyte Growth Factor - metabolism | Adult Stem Cells - metabolism | Adipocytes - metabolism | Ascorbic Acid - pharmacology | Lipopolysaccharides - pharmacology | Adipose Tissue - drug effects | Angiogenic Proteins - metabolism | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 07/2012, Volume 487, Issue 7408, pp. 505 - 509
Mutationally activated kinases define a clinically validated class of targets for cancer drug therapy(1). However, the efficacy of kinase inhibitors in... 
CELL LUNG-CANCER | SURVIVAL | HETEROGENEITY | ACTIVATION | RECEPTOR TYROSINE KINASES | THERAPY | MET AMPLIFICATION | MULTIDISCIPLINARY SCIENCES | ACQUIRED-RESISTANCE | SENSITIVITY | TUMOR-CELLS | Receptor, ErbB-2 - genetics | Humans | Receptor, ErbB-2 - metabolism | Melanoma - enzymology | Phosphatidylinositol 3-Kinases - metabolism | Hepatocyte Growth Factor - pharmacology | Breast Neoplasms - metabolism | Melanoma - genetics | Female | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Cell Survival - drug effects | Melanoma - pathology | Receptor Protein-Tyrosine Kinases - metabolism | Sulfonamides - pharmacology | Breast Neoplasms - drug therapy | Hepatocyte Growth Factor - metabolism | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Breast Neoplasms - genetics | Signal Transduction - drug effects | Breast Neoplasms - pathology | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Cell Line, Tumor | Ligands | Protein Kinase Inhibitors - pharmacology | Quinazolines - pharmacology | Drug Resistance, Neoplasm - drug effects | Mitogen-Activated Protein Kinases - metabolism | Antimitotic agents | Physiological aspects | Antineoplastic agents | Growth factors | Health aspects | Phosphotransferases | Substance abuse treatment | Epidermal growth factor | Rodents | Biomarkers | Breast cancer | Insulin-like growth factors | Kinases | Drug resistance | Tumors | Index Medicus
Journal Article
Nature Neuroscience, ISSN 1097-6256, 06/2012, Volume 15, Issue 6, pp. 862 - 870
Journal Article
Cancer Cell, ISSN 1535-6108, 2008, Volume 14, Issue 5, pp. 382 - 393
A key step in angiogenesis is the upregulation of growth factor receptors on endothelial cells. Here, we demonstrate that a small regulatory microRNA, miR-296,... 
CELLCYCLE | THERAPY | ONCOLOGY | VASCULAR INTEGRITY | IN-VIVO | GENE-EXPRESSION | DEGRADATION | TARGETS | OCULAR NEOVASCULARIZATION | TUMOR ANGIOGENESIS | MICRORNAS | CANCER | CELL BIOLOGY | Endothelium, Vascular - cytology | Luciferases - metabolism | MicroRNAs - antagonists & inhibitors | Humans | Neovascularization, Pathologic | Molecular Sequence Data | MicroRNAs - metabolism | Brain Neoplasms - blood supply | Phosphoproteins - antagonists & inhibitors | Phosphoproteins - metabolism | RNA, Messenger - metabolism | Receptor, Platelet-Derived Growth Factor beta - genetics | Brain Neoplasms - metabolism | Glioma - metabolism | Vascular Endothelial Growth Factor Receptor-2 - genetics | Vascular Endothelial Growth Factor Receptor-2 - antagonists & inhibitors | Kidney - metabolism | Receptor, Platelet-Derived Growth Factor beta - antagonists & inhibitors | Oligonucleotides - pharmacology | Base Sequence | RNA, Messenger - antagonists & inhibitors | Glioma - therapy | Umbilical Veins - cytology | Receptor, Platelet-Derived Growth Factor beta - metabolism | Signal Transduction | Endosomal Sorting Complexes Required for Transport | RNA, Messenger - genetics | RNA, Small Interfering - pharmacology | Cells, Cultured | Angiogenesis Inhibitors - pharmacology | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Kidney - cytology | Phosphoproteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Sequence Homology, Nucleic Acid | Blotting, Western | Hepatocyte Growth Factor - metabolism | Glioma - blood supply | Xenograft Model Antitumor Assays | Magnetic Resonance Imaging | Animals | Endothelium, Vascular - metabolism | Brain Neoplasms - therapy | Fluorescent Antibody Technique | Mice | MicroRNAs - genetics | Cell Movement | Umbilical Veins - metabolism | Tyrosine | Medical colleges | Neurosciences | Messenger RNA | Gliomas | Oncology, Experimental | Brain tumors | Research | Growth factors | Cancer | Endothelium | Index Medicus | PDGFR | VEGFR | miRNA | cancer | HGS | angiogenesis
Journal Article
Journal Article
BJU International, ISSN 1464-4096, 09/2013, Volume 112, Issue 5, pp. 686 - 696
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 03/2008, Volume 294, Issue 3, pp. 675 - 682
Understanding the mechanisms by which adult stem cells produce growth factors may represent an important way to optimize their beneficial paracrine and... 
Fibroblast growth factor 2 | Mitogen-activated protein kinase | Hepatocyte growth factor | Insulin-like growth factor 1 | Vascular endothelial growth factor | PROGENITOR CELLS | KINASE PATHWAY | PHYSIOLOGY | VENTRICULAR-FUNCTION | VEGF | BONE-MARROW | TRAUMA-HEMORRHAGE | INFARCTED MYOCARDIUM | CELL BIOLOGY | mitogen-activated protein kinase | IN-VITRO | vascular endothelial growth factor | fibroblast growth factor 2 | hepatocyte growth factor | CARDIAC-SURGERY | insulin-like growth factor 1 | STROMAL CELLS | Mesenchymal Stromal Cells - enzymology | Tumor Necrosis Factor-alpha - metabolism | Phosphorylation | Humans | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | JNK Mitogen-Activated Protein Kinases - metabolism | NF-kappa B - metabolism | Peptide Fragments - pharmacology | Vascular Endothelial Growth Factor A - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Cell Hypoxia | Intercellular Signaling Peptides and Proteins - metabolism | Cell Shape | Fibroblast Growth Factor 2 - metabolism | Mesenchymal Stromal Cells - drug effects | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Paracrine Communication | Cells, Cultured | Mesenchymal Stromal Cells - metabolism | Hepatocyte Growth Factor - metabolism | Signal Transduction - drug effects | Lipopolysaccharides - pharmacology | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Insulin-Like Growth Factor I - metabolism | Index Medicus
Journal Article
Circulation Research, ISSN 0009-7330, 03/2010, Volume 106, Issue 5, pp. 971 - 980
Journal Article
Journal Article
Journal Article