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1. Full Text MicroRNA-375 is induced in cisplatin nephrotoxicity to repress hepatocyte nuclear factor 1-β
by Hao, Jielu and Lou, Qiang and Wei, Qingqing and Mei, Shuqin and Li, Lin and Wu, Guangyu and Mi, Qing-Sheng and Mei, Changlin and Dong, Zheng
The Journal of biological chemistry, ISSN 0021-9258, 03/2017, Volume 292, Issue 11, pp. 4571 - 4582
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Gene Expression Regulation - drug effects | Kidney - metabolism | Animals | Cisplatin - toxicity | Kidney - drug effects | Ribonuclease III - genetics | Apoptosis - drug effects | Mice | MicroRNAs - genetics | Hepatocyte Nuclear Factor 1-beta - genetics | Antineoplastic Agents - toxicity | Mice, Knockout | Index Medicus | Molecular Bases of Disease | kidney | NF-κB | microRNA (miRNA) | nephrotoxicity | gene regulation | apoptosis | cisplatin | P53
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2. Full Text Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b
by Kornfeld, Jan-Wilhelm and Baitzel, Catherina and Könner, A. Christine and Nicholls, Hayley T and Vogt, Merly C and Herrmanns, Karolin and Scheja, Ludger and Haumaitre, Cécile and Wolf, Anna M and Knippschild, Uwe and Seibler, Jost and Cereghini, Silvia and Heeren, Joerg and Stoffel, Markus and Brüning, Jens C
Nature (London), ISSN 0028-0836, 02/2013, Volume 494, Issue 7435, pp. 111 - 115
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Glucose Intolerance - metabolism | Glucose Intolerance - genetics | Signal Transduction | Humans | Liver - metabolism | Gene Expression Regulation | Gene Silencing | Hepatocyte Nuclear Factor 1-beta - deficiency | MicroRNAs - biosynthesis | Glucose - biosynthesis | Obesity - genetics | Insulin - metabolism | Animals | Insulin Resistance - genetics | Glucose - metabolism | Mice | MicroRNAs - genetics | Hepatocyte Nuclear Factor 1-beta - genetics | Gluconeogenesis | Hepatocyte Nuclear Factor 1-beta - metabolism | Glucose metabolism | Obesity | Gene silencing | MicroRNA | Physiological aspects | Development and progression | Genetic aspects | Research | Gene expression | Health aspects | Rodents | Insulin resistance | Diabetes | Glucose | Metabolism | Insulin | Index Medicus | Life Sciences | Development Biology
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3. Full Text Transcription factor hepatocyte nuclear factor-1β (HNF-1β) regulates microRNA-200 expression through a long noncoding RNA
by Hajarnis, Sachin S and Patel, Vishal and Aboudehen, Karam and Attanasio, Massimo and Cobo-Stark, Patricia and Pontoglio, Marco and Igarashi, Peter
The Journal of biological chemistry, ISSN 0021-9258, 10/2015, Volume 290, Issue 41, pp. 24793 - 24805
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Epithelial Cells - metabolism | Genomics | Humans | Gene Expression Regulation | Repressor Proteins - genetics | Hepatocyte Nuclear Factor 1-beta - deficiency | Kidney - cytology | RNA, Long Noncoding - genetics | Gene Knockout Techniques | Zinc Finger E-box Binding Homeobox 2 | Homeodomain Proteins - genetics | TRPP Cation Channels - genetics | Animals | Base Sequence | Mice | MicroRNAs - genetics | HeLa Cells | Mutation | Hepatocyte Nuclear Factor 1-beta - genetics | Hepatocyte Nuclear Factor 1-beta - metabolism | Index Medicus | Molecular Bases of Disease | epithelial-mesenchymal transition (EMT) | kidney | transcription regulation | long noncoding RNA (long ncRNA, lncRNA) | microRNA (miRNA) | hepatocyte nuclear factor 1 (HNF-1) | ChIP-sequencing (ChIP-seq)
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4. Full Text Diabetes, associated clinical spectrum, long-term prognosis, and genotype/phenotype correlations in 201 adult patients with hepatocyte nuclear factor 1B (HNF1B) molecular defects
by Dubois-Laforgue, Danièle and Cornu, Erika and Saint-Martin, Cécile and Coste, Joël and Bellanné-Chantelot, Christine and Timsit, José and Soc Francophone Diabet and Monogenic Diabetes Study Group of the Société Francophone du Diabète
Diabetes care, ISSN 0149-5992, 11/2017, Volume 40, Issue 11, pp. 1436 - 1443
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Prognosis | Follow-Up Studies | Diabetes Mellitus, Type 2 - genetics | Humans | Kidney Diseases - diagnosis | Male | Cardiovascular Diseases - genetics | Kidney Diseases - genetics | Diabetic Retinopathy - complications | Young Adult | Diabetic Retinopathy - diagnosis | Gene Deletion | Kidney Diseases - epidemiology | Cardiovascular Diseases - epidemiology | Adult | Female | Kidney Diseases - complications | Retrospective Studies | Child | Diabetes Mellitus, Type 2 - complications | Hepatocyte Nuclear Factor 1-beta - genetics | Hepatocyte Nuclear Factor 1-beta - metabolism | Body Mass Index | Cardiovascular Diseases - etiology | Genetic Association Studies | Risk Factors | Diabetic Retinopathy - genetics | Diabetes Mellitus, Type 2 - diagnosis | Diabetic Retinopathy - epidemiology | Adolescent | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Insulin - therapeutic use | Kidneys | Diabetes | Diagnosis | Research | Liver cells | Health aspects | Causes and theories of causation | Diseases | End-stage renal disease | Correlation | Retinopathy | Cardiovascular disease | Neuropathy | Risk factors | Defects | Genotype & phenotype | Etiology | Complications | Abnormalities | Diabetes mellitus | Health risks | Risk analysis | Insulin | Patients | Cysts | Adults | Research design | Kidney diseases | Mutation | Cardiovascular diseases | Kidney transplantation | Index Medicus
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5. Full Text Pancreatic Exocrine Duct Cells Give Rise to Insulin-Producing β Cells during Embryogenesis but Not after Birth
by Solar, Myriam and Cardalda, Carina and Houbracken, Isabelle and Martín, Mercè and Maestro, Miguel Angel and De Medts, Nele and Xu, Xiaobo and Grau, Vanessa and Heimberg, Harry and Bouwens, Luc and Ferrer, Jorge
Developmental cell, ISSN 1534-5807, 2009, Volume 17, Issue 6, pp. 849 - 860
STEMCELL | HUMDISEASE | DEVBIO | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Cell physiology | Molecular and cellular biology | Cell differentiation, maturation, development, hematopoiesis | Animals | Mice, Inbred C57BL | Pancreas - cytology | Female | Male | Mice, Transgenic | Insulin-Secreting Cells - cytology | Mice | Pancreas, Exocrine - embryology | Pancreas - embryology | Hepatocyte Nuclear Factor 1-beta - genetics | Hepatocyte Nuclear Factor 1-beta - metabolism | Index Medicus
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6. Full Text Hepatocyte nuclear factor 1β controls nephron tubular development
by Massa, Filippo and Garbay, Serge and Bouvier, Raymonde and Sugitani, Yoshinobu and Noda, Tetsuo and Gubler, Marie-Claire and Heidet, Laurence and Pontoglio, Marco and Fischer, Evelyne
Development (Cambridge), ISSN 0950-1991, 02/2013, Volume 140, Issue 4, pp. 886 - 896
CAKUT | Notch pathway | HNF1β | MODY5 | Kidney development | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Immunohistochemistry | Nephrons - embryology | Homeodomain Proteins - metabolism | Gene Expression Regulation, Developmental - genetics | Nephrons - abnormalities | Microscopy, Electron | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Animals | In Situ Hybridization | Chromatin Immunoprecipitation | Nephrons - ultrastructure | Organogenesis - genetics | Mice | Organogenesis - physiology | Real-Time Polymerase Chain Reaction | Hepatocyte Nuclear Factor 1-beta - genetics | Gene Expression Regulation, Developmental - physiology | Hepatocyte Nuclear Factor 1-beta - metabolism | POU Domain Factors - metabolism | Index Medicus
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7. Full Text Prognostic relevance of molecular subtypes and master regulators in pancreatic ductal adenocarcinoma
by Janky, Rekin's and Binda, Maria Mercedes and Allemeersch, Joke and Van den broeck, Anke and Govaere, Olivier and Swinnen, Johannes V and Roskams, Tania and Aerts, Stein and Topal, Baki
BMC cancer, ISSN 1471-2407, 08/2016, Volume 16, Issue 1, pp. 632 - 632
Molecular subtypes | Pancreatic ductal adenocarcinoma | HNF1A/B | Master regulators | Life Sciences & Biomedicine | Oncology | Science & Technology | Prognosis | Hepatocyte Nuclear Factor 1-alpha - genetics | Oligonucleotide Array Sequence Analysis - methods | Humans | Gene Expression Regulation, Neoplastic | Gene Expression Profiling - methods | Male | Pancreatic Neoplasms - genetics | Gene Regulatory Networks | Hepatocyte Nuclear Factor 1-alpha - metabolism | Carcinoma, Pancreatic Ductal - genetics | Regression Analysis | Survival Analysis | Female | Hepatocyte Nuclear Factor 1-beta - genetics | Hepatocyte Nuclear Factor 1-beta - metabolism | Immunohistochemistry | Care and treatment | Pancreatic cancer | Diagnosis | DNA binding proteins | Research | Genetic transcription | Index Medicus
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8. Full Text HNF1B-associated renal and extra-renal disease - An expanding clinical spectrum
by Clissold, Rhian L and Hamilton, Alexander J and Hattersley, Andrew T and Ellard, Sian and Bingham, Coralie
Nature reviews. Nephrology, ISSN 1759-5061, 02/2015, Volume 11, Issue 2, pp. 102 - 112
Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Phenotype | Hepatocyte Nuclear Factor 1-beta - physiology | Humans | Kidney Diseases - etiology | Mutation | Hepatocyte Nuclear Factor 1-beta - genetics | Kidney Diseases - genetics | Physiological aspects | Development and progression | Transcription factors | Genetic aspects | Kidney diseases | Research | Index Medicus
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9. Full Text Genome-wide association study identifies a common variant associated with risk of endometrial cancer
by Spurdle, Amanda B and Thompson, Deborah J and Ahmed, Shahana and Ferguson, Kaltin and Healey, Catherine S and O'Mara, Tracy and Walker, Logan C and Montgomery, Stephen B and Dermitzakis, Emmanouil T and Fahey, Paul and Montgomery, Grant W and Webb, Penelope M and Fasching, Peter A and Beckmann, Matthias W and Ekici, Arif B and Hein, Alexander and Lambrechts, Diether and Coenegrachts, Lieve and Vergote, Ignace and Amant, Frederic and Salvesen, Helga B and Trovik, Jone and Njolstad, Tormund S and Helland, Harald and Scott, Rodney J and Ashton, Katie and Proietto, Tony and Otton, Geoffrey and Tomlinson, Ian and Gorman, Maggie and Howarth, Kimberley and Hodgson, Shirley and Garcia-Closas, Montserrat and Wentzensen, Nicolas and Yang, Hannah and Chanock, Stephen and Hall, Per and Czene, Kamila and Liu, Jianjun and Li, Jingmei and Shu, Xiao-Ou and Zheng, Wei and Long, Jirong and Xiang, Yong-Bing and Shah, Mitul and Morrison, Jonathan and Michailidou, Kyriaki and Pharoah, Paul D and Dunning, Alison M and Easton, Douglas F and Australian Natl Endometrial Canc and Natl Study Endometrial Canc Geneti and Australian National Endometrial Cancer Study Group and National Study of Endometrial Cancer Genetics Group and The Australian National Endometrial Cancer Study Group
Nature genetics, ISSN 1061-4036, 05/2011, Volume 43, Issue 5, pp. 451 - 455
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Gynecology. Andrology. Obstetrics | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Female genital diseases | Tumors | Genetic Predisposition to Disease | Genome-Wide Association Study | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Risk Factors | Male | Case-Control Studies | Genetic Variation | Young Adult | Prostatic Neoplasms - genetics | Endometrial Neoplasms - genetics | Adolescent | Aged, 80 and over | Adult | Female | Aged | Polymorphism, Single Nucleotide | Odds Ratio | Hepatocyte Nuclear Factor 1-beta - genetics | Disease susceptibility | Genetic aspects | Single nucleotide polymorphisms | Research | Endometrial cancer | Risk factors | Studies | Medical research | Genetics | Breast cancer | Index Medicus | Medicin och hälsovetenskap
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10. Full Text Regulation of HSulf-1 expression by variant hepatic nuclear factor 1 in ovarian cancer
by Liu, Peng and Khurana, Ashwani and Rattan, Ramandeep and He, Xiaoping and Kalloger, Steve and Dowdy, Sean and Gilks, Blake and Shridhar, Viji
Cancer research (Chicago, Ill.), ISSN 0008-5472, 06/2009, Volume 69, Issue 11, pp. 4843 - 4850
Life Sciences & Biomedicine | Oncology | Science & Technology | Gynecology. Andrology. Obstetrics | Pharmacology. Drug treatments | Biological and medical sciences | Medical sciences | Antineoplastic agents | Tumors | Female genital diseases | Sulfotransferases - genetics | Oligonucleotide Array Sequence Analysis | Response Elements | Hepatocyte Nuclear Factor 1-beta - physiology | Humans | RNA, Small Interfering - pharmacology | Hepatocyte Nuclear Factor 1-beta - antagonists & inhibitors | Ovarian Neoplasms - pathology | Gene Expression Profiling | Ovarian Neoplasms - genetics | Xenograft Model Antitumor Assays | Animals | Transfection | Mice, Nude | Cell Line, Tumor | Protein Binding | Carcinoma - genetics | Female | Mice | Gene Expression Regulation, Neoplastic - drug effects | Sulfotransferases - physiology | Carcinoma - pathology | Hepatocyte Nuclear Factor 1-beta - genetics | Hepatocyte Nuclear Factor 1-beta - metabolism | Index Medicus | ovarian cancer | HSulf-1 | vHNF1
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