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animals (112) 112
hepatocyte nuclear factor 3-gamma (69) 69
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index medicus (54) 54
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hepatocyte nuclear factor 3-gamma - metabolism (45) 45
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base sequence (42) 42
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Journal Article
Nature, ISSN 0028-0836, 07/2011, Volume 475, Issue 7356, pp. 386 - 391
The generation of functional hepatocytes independent of donor liver organs is of great therapeutic interest with regard to regenerative medicine and possible... 
MURINE MODEL | HEPATIC-DYSFUNCTION | PANCREAS PROGENITORS | TYROSINEMIA TYPE-I | LIVER-FUNCTION | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | FACTOR NETWORK | DIRECT CONVERSION | GENE-EXPRESSION | ENRICHED TRANSCRIPTION FACTORS | Hydrolases - genetics | Liver - enzymology | Hepatocyte Nuclear Factor 1-alpha - genetics | Tail - cytology | Liver Diseases - pathology | Gene Expression Profiling | Hepatocyte Nuclear Factor 3-gamma - genetics | Hepatocytes - metabolism | Hepatocyte Nuclear Factor 1-alpha - metabolism | Liver - physiopathology | Regenerative Medicine - methods | DNA-Binding Proteins - deficiency | Cell Differentiation - genetics | Hepatocytes - cytology | Hepatocyte Nuclear Factor 3-gamma - metabolism | Liver Diseases - enzymology | Hepatocytes - transplantation | Hepatocytes - physiology | Fibroblasts - metabolism | Cyclin-Dependent Kinase Inhibitor p16 - deficiency | GATA4 Transcription Factor - metabolism | Tissue Engineering - methods | Transduction, Genetic | Cells, Cultured | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Liver Diseases - therapy | GATA4 Transcription Factor - genetics | Survival Rate | Hydrolases - deficiency | Mice, SCID | Cell Lineage | Animals | Liver - physiology | Mice, Inbred NOD | Fibroblasts - cytology | Liver - cytology | Mice | Liver Diseases - physiopathology | Physiological aspects | Fibroblasts | Transcription factors | Research | Embryonic stem cells | Liver cells | Proteins | Gene expression | Tissue engineering | Cell adhesion & migration
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2014, Volume 111, Issue 39, pp. 14289 - 14294
Aging is associated with increased adiposity and diminished thermogenesis, but the critical transcription factors influencing these metabolic changes late in... 
Adipose tissues | Obesity | Messenger RNA | White adipose tissue | Developmental biology | Brown adipose tissue | Brown adipocytes | Insulin resistance | Adipocytes | Lipid metabolism | Diabetes | PGC-1-ALPHA | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | BROWN ADIPOSE-TISSUE | GLUCOSE-HOMEOSTASIS | ENERGY-EXPENDITURE | INSULIN-RESISTANCE | FAT | NUCLEAR FACTOR 3-GAMMA | ADIPOCYTE DIFFERENTIATION | MICE | diabetes | obesity | Thermogenesis - genetics | Up-Regulation | Adipose Tissue, White - metabolism | Male | Hepatocyte Nuclear Factor 3-gamma - genetics | RNA, Messenger - metabolism | Obesity - genetics | Thermogenesis - physiology | Aging - genetics | Hepatocyte Nuclear Factor 3-gamma - metabolism | Insulin Resistance - physiology | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Hepatocyte Nuclear Factor 3-gamma - deficiency | Energy Metabolism - genetics | Energy Metabolism - physiology | Promoter Regions, Genetic | RNA, Messenger - genetics | Longevity - genetics | Transcription Factors - genetics | Adiposity - genetics | Mice, Knockout | Obesity - metabolism | Transcription Factors - metabolism | Animals | Cyclic AMP Response Element-Binding Protein - metabolism | Insulin Resistance - genetics | Adipose Tissue, Brown - metabolism | Adiposity - physiology | Mice | Longevity - physiology | Aging - metabolism | Transcription factors | Analysis | Physiological aspects | Aging | Physiological research | Research | Metabolism | Protein binding | Biological Sciences
Journal Article
Journal Article
Developmental Cell, ISSN 1534-5807, 05/2012, Volume 22, Issue 5, pp. 927 - 939
During endochondral ossification, small, immature chondrocytes enlarge to form hypertrophic chondrocytes, which express collagen X. In this work, we... 
TRANSCRIPTION FACTORS | TARGETED DISRUPTION | CBFA1-DEFICIENT MICE | BONE-FORMATION | X COLLAGEN GENE | ALKALINE-PHOSPHATASE | ENHANCER | CBFA1 | NUCLEAR FACTOR 3-GAMMA | DEVELOPMENTAL BIOLOGY | EXPRESSION | CELL BIOLOGY | Chondrocytes - cytology | Hepatocyte Nuclear Factor 3-beta - genetics | Chondrogenesis - genetics | Alkaline Phosphatase - metabolism | Hepatocyte Nuclear Factor 3-gamma - genetics | Core Binding Factor Alpha 1 Subunit - metabolism | Embryo, Mammalian - metabolism | Cell Differentiation - genetics | Collagen Type X - metabolism | Hepatocyte Nuclear Factor 3-gamma - metabolism | Mice, Mutant Strains | Hepatocyte Nuclear Factor 3-gamma - deficiency | Binding Sites | Chondrocytes - metabolism | Genes, Reporter | Fibroblasts - metabolism | Hepatocyte Nuclear Factor 3-beta - metabolism | Dwarfism - embryology | Matrix Metalloproteinase 13 - genetics | Cells, Cultured | Metatarsal Bones - cytology | Myogenic Regulatory Factors - metabolism | Collagen Type X - genetics | Metatarsal Bones - metabolism | Cell Enlargement | Growth Plate - metabolism | Chick Embryo | Matrix Metalloproteinase 13 - metabolism | Dwarfism - genetics | Animals | Embryo, Mammalian - cytology | Smad1 Protein - metabolism | Fibroblasts - cytology | Mice | Hepatocyte Nuclear Factor 3-beta - deficiency | Physiological aspects | Phosphatases | Collagen | Genes | Alkaline phosphatase | Collagenase 3 | Ossification | Dwarfism | Growth plate | Enhancers | Collagen (type X) | Mineralization | Chondrocytes | Fibroblasts | Chondrogenesis | Bone (endochondral) | Hypertrophy
Journal Article
Cell Reports, ISSN 2211-1247, 01/2015, Volume 10, Issue 2, pp. 239 - 252
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 02/2014, Volume 189, Issue 3, pp. 301 - 313
Journal Article