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Journal Article
Nature, ISSN 0028-0836, 07/2011, Volume 475, Issue 7356, pp. 386 - 391
The generation of functional hepatocytes independent of donor liver organs is of great therapeutic interest with regard to regenerative medicine and possible... 
MURINE MODEL | HEPATIC-DYSFUNCTION | PANCREAS PROGENITORS | TYROSINEMIA TYPE-I | LIVER-FUNCTION | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | FACTOR NETWORK | DIRECT CONVERSION | GENE-EXPRESSION | ENRICHED TRANSCRIPTION FACTORS | Hydrolases - genetics | Liver - enzymology | Hepatocyte Nuclear Factor 1-alpha - genetics | Tail - cytology | Liver Diseases - pathology | Gene Expression Profiling | Hepatocyte Nuclear Factor 3-gamma - genetics | Hepatocytes - metabolism | Hepatocyte Nuclear Factor 1-alpha - metabolism | Liver - physiopathology | Regenerative Medicine - methods | DNA-Binding Proteins - deficiency | Cell Differentiation - genetics | Hepatocytes - cytology | Hepatocyte Nuclear Factor 3-gamma - metabolism | Liver Diseases - enzymology | Hepatocytes - transplantation | Hepatocytes - physiology | Fibroblasts - metabolism | Cyclin-Dependent Kinase Inhibitor p16 - deficiency | GATA4 Transcription Factor - metabolism | Tissue Engineering - methods | Transduction, Genetic | Cells, Cultured | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Liver Diseases - therapy | GATA4 Transcription Factor - genetics | Survival Rate | Hydrolases - deficiency | Mice, SCID | Cell Lineage | Animals | Liver - physiology | Mice, Inbred NOD | Fibroblasts - cytology | Liver - cytology | Mice | Liver Diseases - physiopathology | Physiological aspects | Fibroblasts | Transcription factors | Research | Embryonic stem cells | Liver cells | Proteins | Gene expression | Tissue engineering | Cell adhesion & migration | Index Medicus
Journal Article
Shui sheng sheng wu xue bao, ISSN 1000-3207, 01/2017, Volume 41, Issue 6, pp. 1301 - 1316
The objective of this study was to explore the mechanism and effect of silymarin on hepatocytes lipid accumulation of grass carp(Ctenopharyngodon idellus)... 
Hepatocytes
Journal Article
eLife, ISSN 2050-084X, 11/2012, Volume 2012, Issue 1, pp. e00049 - e00049
Human hepatitis B virus (HBV) infection and HBV-related diseases remain a major public health problem. Individuals coinfected with its satellite hepatitis D... 
viruses | receptor | Sodium taurocholate cotransporting polypeptide | hepatitis D virus | infectious disease | liver | hepatitis B virus | biochemistry | microbiology | virus infection | CLOSED CIRCULAR DNA | IN-VITRO | HEPATOCELLULAR-CARCINOMA | DELTA-VIRUS | TUPAIA HEPATOCYTES | RAT HEPATOCYTES | ADULT HUMAN HEPATOCYTES | BIOLOGY | PRE-S SEQUENCE | LARGE SURFACE PROTEIN | ENVELOPE PROTEINS | Liver - virology | Liver - pathology | Receptors, Virus - metabolism | Taurocholic Acid - metabolism | Humans | Hepatitis Delta Virus - metabolism | Molecular Sequence Data | Hepatocytes - pathology | Hepatocytes - metabolism | Receptors, Virus - genetics | Virus Internalization | Organic Anion Transporters, Sodium-Dependent - genetics | Photochemical Processes | Organic Anion Transporters, Sodium-Dependent - chemistry | Biological Transport | Hepatitis B virus - chemistry | Tupaia | Viral Envelope Proteins - metabolism | Hepatitis Delta Virus - genetics | Protein Structure, Tertiary | Amino Acid Sequence | Cell Line | Gene Expression | Viral Envelope Proteins - genetics | Peptides - chemistry | Liver - metabolism | Symporters - chemistry | Symporters - metabolism | Animals | Hepatitis Delta Virus - chemistry | Receptors, Virus - chemistry | Symporters - genetics | Viral Envelope Proteins - chemistry | Hepatitis B virus - genetics | Hepatocytes - virology | Protein Binding | Hepatitis B virus - metabolism | Primary Cell Culture | Organic Anion Transporters, Sodium-Dependent - metabolism | Antigens | Polypeptides | Liver | Envelope protein | Amino acids | Viruses | Infections | Genomes | Proteins | Hepatitis | Sodium | Rodents | Public health | Viral infections | Hepatitis B | Index Medicus
Journal Article
Journal Article
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 513, Issue 7516, pp. 110 - 114
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2015, Volume 63, Issue 4, pp. 934 - 942
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 01/2006, Volume 34, Issue 1, pp. 75 - 83
Most human hepatocyte cell lines lack a substantial set of liver-specific functions, especially major cytochrome P450 (P450)-related enzyme activities, making... 
MAINTENANCE | RAT HEPATOCYTES | ADULT HUMAN HEPATOCYTES | LIVER | LINE | CULTURED HUMAN HEPATOCYTES | PHARMACOLOGY & PHARMACY | AFLATOXIN B-1 | DIMETHYL-SULFOXIDE | INDUCTION | DRUG-METABOLIZING-ENZYMES | Aflatoxin B1 - pharmacology | Cell Survival - drug effects | Gene Expression - drug effects | Isoenzymes - genetics | Humans | RNA, Messenger - genetics | RNA, Messenger - analysis | Chlorpromazine - pharmacology | Dimethyl Sulfoxide - pharmacology | Gene Expression Profiling | Receptors, Cytoplasmic and Nuclear - genetics | Hepatocytes - metabolism | Xenobiotics - pharmacology | Glucuronosyltransferase - genetics | Hepatocytes - cytology | Acetaminophen - pharmacology | Carcinoma, Hepatocellular - genetics | Reverse Transcriptase Polymerase Chain Reaction - methods | Carcinoma, Hepatocellular - pathology | Cell Line, Tumor | Cytochrome P-450 Enzyme System - genetics | Inhibitory Concentration 50 | Hepatocytes - drug effects | Amiodarone - pharmacology | Index Medicus | Gene Expression | Isoenzymes | Cell Survival | Amiodarone | Reverse Transcriptase Polymerase Chain Reaction | Receptors, Cytoplasmic and Nuclear | Chlorpromazine | Cytochrome P-450 Enzyme System | Life Sciences | Microbiology and Parasitology | Hepatocytes | Acetaminophen | Aflatoxin B1 | Dimethyl Sulfoxide | Carcinoma, Hepatocellular | Xenobiotics | RNA, Messenger | Glucuronosyltransferase
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2015, Volume 125, Issue 4, pp. 1533 - 1544
The cause of organ failure is enigmatic for many degenerative diseases, including end-stage liver disease. Here, using a CCl4-induced rat model of irreversible... 
LONG-TERM | PATHOGENESIS | MEDICINE, RESEARCH & EXPERIMENTAL | NUCLEAR | MECHANISM | CHRONIC LIVER-DISEASE | CIRRHOSIS | RATS | HEPATOCYTE | EXPRESSION | TRANSPLANTATION | Liver Cirrhosis, Experimental - therapy | Liver Failure - etiology | Dependovirus - genetics | Genetic Therapy | Hepatocyte Nuclear Factor 1-alpha - genetics | Hepatocyte Nuclear Factor 3-beta - genetics | Rats, Inbred Lew | Transcriptome | Hepatocyte Nuclear Factor 1-alpha - biosynthesis | Liver Failure - pathology | Hepatocytes - pathology | Male | Gene Expression Profiling | Genetic Vectors - therapeutic use | Hepatocytes - metabolism | Gene Regulatory Networks | Hepatocyte Nuclear Factor 4 - physiology | Recombinant Fusion Proteins - metabolism | CCAAT-Enhancer-Binding Protein-alpha - biosynthesis | Hepatocyte Nuclear Factor 4 - biosynthesis | Liver Cirrhosis, Experimental - pathology | Liver Cirrhosis, Experimental - complications | Hepatocyte Nuclear Factor 3-beta - biosynthesis | Transcription Factors - physiology | Transduction, Genetic | PPAR alpha - biosynthesis | Down-Regulation | Cells, Cultured | Gene Expression Regulation | Rats | PPAR alpha - genetics | Hepatocyte Nuclear Factor 4 - genetics | Liver Cirrhosis, Experimental - genetics | Liver Failure - genetics | Disease Progression | Animals | Carbon Tetrachloride Poisoning - therapy | Liver Failure - therapy | CCAAT-Enhancer-Binding Protein-alpha - genetics | Carbon Tetrachloride Poisoning - genetics | Cell Dedifferentiation - genetics | Transcription factors | Liver diseases | Genetic research | Development and progression | Genetic aspects | Genetic transcription | Research | Properties | Hypertension | Cytochrome | Transplants & implants | Rodents | Stem cells | Metabolism | Laboratory animals | Liver cirrhosis | Index Medicus | Abridged Index Medicus | Hepatology | Gastroenterology
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 12/2017, Volume 232, Issue 12, pp. 3296 - 3308
Journal Article
12.