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Chemical Research in Toxicology, ISSN 0893-228X, 09/2008, Volume 21, Issue 9, pp. 1814 - 1822
In vitro covalent binding assessments of drugs have been useful in providing retrospective insights into the association between drug metabolism and a... 
ACYL GLUCURONIDES | CHEMISTRY, MEDICINAL | PROTEIN | RAT | REACTIVE METABOLITES | TIENILIC ACID | HEPATIC-NECROSIS | BIOACTIVATION | IDENTIFICATION | CHEMISTRY, MULTIDISCIPLINARY | MASS-SPECTROMETRY | TOXICOLOGY | HUMAN URINE | Buspirone - chemistry | Raloxifene Hydrochloride - pharmacology | Thiazoles - metabolism | Acetaminophen - metabolism | Humans | Microsomes, Liver - metabolism | Indomethacin - metabolism | Simvastatin - pharmacology | Diclofenac - chemistry | Thiazines - metabolism | Propranolol - pharmacology | Toxicity Tests - methods | Binding Sites | Simvastatin - metabolism | Microsomes, Liver - chemistry | Indomethacin - pharmacology | Paroxetine - metabolism | Raloxifene Hydrochloride - metabolism | Triazoles - metabolism | Ticrynafen - metabolism | Paroxetine - pharmacology | Diclofenac - metabolism | Paroxetine - chemistry | Diphenhydramine - pharmacology | Diclofenac - pharmacology | Triazoles - chemistry | Buspirone - metabolism | Ticrynafen - pharmacology | Structure-Activity Relationship | Buspirone - pharmacology | Hepatocytes - metabolism | Dose-Response Relationship, Drug | Carbamazepine - chemistry | Diphenhydramine - metabolism | Acetaminophen - pharmacology | Microsomes, Liver - drug effects | Propranolol - metabolism | Carbamazepine - metabolism | Thiazines - pharmacology | Molecular Structure | Drug Evaluation, Preclinical | Hepatocytes - drug effects | Carbamazepine - pharmacology | Simvastatin - chemistry | Acetaminophen - chemistry | Ticrynafen - chemistry | Propranolol - chemistry | Diphenhydramine - chemistry | Thiazines - chemistry | Triazoles - pharmacology | Indomethacin - chemistry | Thiazoles - chemistry | Thiazoles - pharmacology | Raloxifene Hydrochloride - chemistry | Index Medicus
Journal Article
Carbohydrate Research, ISSN 0008-6215, 02/2017, Volume 439, pp. 16 - 22
Glycoprotein N-linked oligosaccharides in the endoplasmic reticulum function as tags to regulate glycoprotein folding, sorting, secretion and degradation.... 
Calreticulin | Glucosidase | Glucosyl transferase | Mannosidase | High-mannose glycan | Aglycone specificity | GLUCOSE-GLYCOPROTEIN-GLUCOSYLTRANSFERASE | UDP-GLUCOSE | SOLUBLE BODIPY DERIVATIVES | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | ER-ASSOCIATED DEGRADATION | QUALITY-CONTROL | SUBSTRATE RECOGNITION | PROTEIN-FOLDING SENSOR | BIOSYNTHESIS | CHEMISTRY, APPLIED | MANNOSE TRIMMING STEP | Mannosidases - chemistry | Cell Fractionation | Glucosidases - metabolism | Glycoproteins - metabolism | Endoplasmic Reticulum - metabolism | Fluorescent Dyes - metabolism | Male | Mannosidases - metabolism | Hepatocytes - metabolism | Acetylglucosamine - metabolism | Glucosidases - chemistry | Glucosyltransferases - metabolism | Mannose - metabolism | Endoplasmic Reticulum - chemistry | Calreticulin - metabolism | Glycoproteins - chemistry | Mannose - chemistry | Boron Compounds - chemistry | Carbohydrate Sequence | Fluorescent Dyes - chemistry | Boron Compounds - metabolism | Liver - metabolism | Mice, Inbred C57BL | Glycosylation | Acetylglucosamine - chemistry | Liver - chemistry | Calreticulin - chemistry | Animals | Glucose - chemistry | Glucosyltransferases - chemistry | Glucose - metabolism | Hydrophobic and Hydrophilic Interactions | Protein Conformation | Hepatocytes - chemistry | Mice | Glycoproteins | Dextrose | Glucose
Journal Article
Nature Methods, ISSN 1548-7091, 02/2006, Volume 3, Issue 2, pp. 123 - 127
Journal Article
eLife, ISSN 2050-084X, 11/2012, Volume 2012, Issue 1, p. e00049
Human hepatitis B virus (HBV) infection and HBV-related diseases remain a major public health problem. Individuals coinfected with its satellite hepatitis D... 
viruses | receptor | Sodium taurocholate cotransporting polypeptide | hepatitis D virus | infectious disease | liver | hepatitis B virus | biochemistry | microbiology | virus infection | CLOSED CIRCULAR DNA | IN-VITRO | HEPATOCELLULAR-CARCINOMA | DELTA-VIRUS | TUPAIA HEPATOCYTES | RAT HEPATOCYTES | ADULT HUMAN HEPATOCYTES | BIOLOGY | PRE-S SEQUENCE | LARGE SURFACE PROTEIN | ENVELOPE PROTEINS | Liver - virology | Liver - pathology | Receptors, Virus - metabolism | Taurocholic Acid - metabolism | Humans | Hepatitis Delta Virus - metabolism | Molecular Sequence Data | Hepatocytes - pathology | Hepatocytes - metabolism | Receptors, Virus - genetics | Virus Internalization | Organic Anion Transporters, Sodium-Dependent - genetics | Photochemical Processes | Organic Anion Transporters, Sodium-Dependent - chemistry | Biological Transport | Hepatitis B virus - chemistry | Tupaia | Viral Envelope Proteins - metabolism | Hepatitis Delta Virus - genetics | Protein Structure, Tertiary | Amino Acid Sequence | Cell Line | Gene Expression | Viral Envelope Proteins - genetics | Peptides - chemistry | Liver - metabolism | Symporters - chemistry | Symporters - metabolism | Animals | Hepatitis Delta Virus - chemistry | Receptors, Virus - chemistry | Symporters - genetics | Viral Envelope Proteins - chemistry | Hepatitis B virus - genetics | Hepatocytes - virology | Protein Binding | Hepatitis B virus - metabolism | Primary Cell Culture | Organic Anion Transporters, Sodium-Dependent - metabolism | Antigens | Polypeptides | Liver | Envelope protein | Amino acids | Viruses | Infections | Genomes | Proteins | Hepatitis | Sodium | Rodents | Public health | Viral infections | Hepatitis B
Journal Article
Bioscience, Biotechnology, and Biochemistry, ISSN 0916-8451, 01/2015, Volume 79, Issue 1, pp. 138 - 146
A new flavanone, shisoflavanone A (1), and several flavonoids were purified from the ethyl acetate-soluble fraction of green perilla leaves (Perilla frutescens... 
flavanone | nitric oxide | chemokine | flavone | green perilla | Chemokine | Flavanone | Flavone | Nitric oxide | Green perilla | GLYCOSIDES | ACID | BIOCHEMISTRY & MOLECULAR BIOLOGY | FOOD SCIENCE & TECHNOLOGY | LEAVES | MONOTERPENE GLUCOSIDES | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CHEMISTRY, APPLIED | CONSTITUENTS | FRUTESCENS | Flavanones - isolation & purification | Plant Extracts - chemistry | Interleukin-1beta - pharmacology | Antioxidants - chemistry | Oxidative Stress | Rats, Wistar | Apigenin - isolation & purification | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Male | Anti-Inflammatory Agents, Non-Steroidal - isolation & purification | Flavones - chemistry | Hepatocytes - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Apigenin - chemistry | Hepatocytes - cytology | Flavanones - chemistry | Luteolin - chemistry | Flavonoids - pharmacology | Flavones - isolation & purification | Flavones - pharmacology | Hepatocytes - drug effects | Interleukin-1beta - antagonists & inhibitors | Plant Leaves - chemistry | Nitric Oxide - biosynthesis | Nitric Oxide - antagonists & inhibitors | Flavanones - pharmacology | Perilla frutescens - chemistry | Rats | Umbelliferones - chemistry | Antioxidants - pharmacology | Luteolin - pharmacology | Umbelliferones - isolation & purification | Umbelliferones - pharmacology | Luteolin - isolation & purification | Animals | Antioxidants - isolation & purification | Flavonoids - isolation & purification | Primary Cell Culture | Flavonoids - chemistry | Apigenin - pharmacology | Index Medicus
Journal Article
Journal Article
Journal of Food Science, ISSN 0022-1147, 08/2011, Volume 76, Issue 6, pp. C869 - C873
:  The biological activities of the mulberry (Morus alba L.) leaf have been attributed to its flavonoid content. The water extract of the mulberry leaf (WEML)... 
cellular antioxidant capacity | mulberry leaf | flavonol | oxygen radical absorbance capacity (ORAC) | Oxygen radical absorbance capacity (ORAC) | Mulberry leaf | Flavonol | Cellular antioxidant capacity | FRUITS | TEA | FOOD SCIENCE & TECHNOLOGY | LEAVES | ASSAYS | MICE | VEGETABLES | STRESS | Free Radical Scavengers - pharmacology | Plant Extracts - chemistry | Antioxidants - chemistry | Free Radical Scavengers - chemistry | Humans | Rutin - pharmacology | Acetates - chemistry | Chromatography, High Pressure Liquid | Copper - chemistry | Acetates - analysis | Reducing Agents - analysis | Water - chemistry | Free Radical Scavengers - analysis | Antioxidants - analysis | Glycosides - chemistry | Reducing Agents - chemistry | Hepatocytes - drug effects | Chelating Agents - analysis | Plant Leaves - chemistry | Quercetin - analogs & derivatives | Glycosides - analysis | Quercetin - chemistry | Flavonols - analysis | Quercetin - analysis | Chelating Agents - chemistry | Plant Extracts - isolation & purification | Rutin - analysis | Antioxidants - pharmacology | Chelating Agents - pharmacology | Flavonols - chemistry | Glycosides - pharmacology | Reducing Agents - pharmacology | Hep G2 Cells | Quercetin - pharmacology | Rutin - chemistry | Acetates - pharmacology | Flavonols - pharmacology | Oxidative Stress - drug effects | Food, Formulated - analysis | Morus - chemistry | Antioxidants | Mulberry | Flavonoids | Composition | Flavones | Bioflavonoids | Chemical properties | Materia medica, Vegetable | Plant extracts | Flavonols | Cellular | Functional foods | Glycosides | Foods | Radicals
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 09/2016, Volume 116, pp. 130 - 139
The P2X7 receptor (P2X7R) plays an important role in diverse conditions associated with tissue damage and inflammation, meaning that the human P2X7R (hP2X7R)... 
YO-PRO-1 dye uptake | Virtual screening | hP2X7R antagonists | Patch-clamp recording | Ca2+ imaging | imaging | ACTIVATION | RAT | EFFICACY | SAFETY | DOCKING | CELL-DEATH | P2X RECEPTOR | CHEMISTRY | PHARMACOLOGY & PHARMACY | INHIBITORS | Humans | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Purinergic P2X Receptor Antagonists - pharmacology | Thiophenes - metabolism | Structure-Activity Relationship | Hepatocytes - metabolism | Receptors, Purinergic P2X3 - genetics | Receptors, Purinergic P2X7 - genetics | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Adenosine Triphosphate - pharmacology | Hepatocytes - cytology | Indoles - metabolism | Adenosine Triphosphate - metabolism | HEK293 Cells | Amides - metabolism | Indoles - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Single-Cell Analysis | Binding Sites | Hepatocytes - drug effects | Amides - pharmacology | Recombinant Proteins - metabolism | Models, Molecular | Rats | Recombinant Proteins - chemistry | Thiophenes - pharmacology | Adenosine Triphosphate - analogs & derivatives | Patch-Clamp Techniques | Animals | Receptors, Purinergic P2X3 - chemistry | Image Processing, Computer-Assisted | Calcium Signaling - drug effects | Purinergic P2X Receptor Antagonists - chemistry | Receptors, Purinergic P2X3 - metabolism | Small Molecule Libraries | Receptors, Purinergic P2X4 - chemistry | Amides - chemistry | Purinergic P2X Receptor Antagonists - metabolism | Receptors, Purinergic P2X7 - metabolism | Ligands | Receptors, Purinergic P2X7 - chemistry | Adenosine Triphosphate - chemistry | Receptors, Purinergic P2X4 - metabolism | Thiophenes - chemistry | Indoles - chemistry | Microscopy, Fluorescence | Receptors, Purinergic P2X4 - genetics | PI, propidium iodide | zfP2X4R, zebrafish P2X4 receptor | HEK293 cells, human embryonic kidney 293 cells | TNP-ATP, trinitrophenyl-ATP | BzATP, 2,3-O-(4-benzoylbenzoyl)-ATP | BBG, brilliant blue G | rP2X7R, rat P2X7R | P2X7R, P2X7 receptor | hP2X7R, human P2X7R
Journal Article
Journal Article