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1. Full Text Terlipressin plus albumin versus midodrine and octreotide plus albumin in the treatment of hepatorenal syndrome: A randomized trial
by Cavallin, Marta and Kamath, Patrick S and Merli, Manuela and Fasolato, Silvano and Toniutto, Pierluigi and Salerno, Francesco and Bernardi, Mauro and Romanelli, Roberto Giulio and Colletta, Cosimo and Salinas, Freddy and Di Giacomo, Antonio and Ridola, Lorenzo and Fornasiere, Ezio and Caraceni, Paolo and Morando, Filippo and Piano, Salvatore and Gatta, Angelo and Angeli, Paolo and Italian Assoc Study Liver Study and Italian Association for the Study of the Liver Study Group on Hepatorenal Syndrome
Hepatology, ISSN 0270-9139, 08/2015, Volume 62, Issue 2, pp. 567 - 574
Hepatorenal syndrome (HRS), a serious complication of cirrhosis, is associated with high mortality without treatment. Terlipressin with albumin is effective in... 
SURVIVAL | PILOT | THERAPY | ASCITES | CIRRHOSIS | PREDICTORS | VASOCONSTRICTORS | TYPE-1 | NORADRENALINE | GASTROENTEROLOGY & HEPATOLOGY | TRANSPLANTATION | Liver Function Tests | Predictive Value of Tests | Lypressin - administration & dosage | Follow-Up Studies | Midodrine - administration & dosage | Humans | Middle Aged | Kaplan-Meier Estimate | Albumins - administration & dosage | Male | Treatment Outcome | Hepatorenal Syndrome - diagnosis | Lypressin - analogs & derivatives | Hepatorenal Syndrome - mortality | Kidney Function Tests | Analysis of Variance | Hepatorenal Syndrome - drug therapy | Survival Analysis | Female | Aged | Infusions, Intravenous | Octreotide - administration & dosage | Drug Therapy, Combination
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2. Full Text Systematic review of randomized trials on vasoconstrictor drugs for hepatorenal syndrome
by Gluud, Lise L and Christensen, Kurt and Christensen, Erik and Krag, Aleksander
Hepatology, ISSN 0270-9139, 02/2010, Volume 51, Issue 2, pp. 576 - 584
Vasoconstrictor drugs may improve renal function in hepatorenal syndrome (HRS), but the effect on mortality has not been established. We therefore performed a... 
PILOT | NONINFERIORITY | TERLIPRESSIN | CIRRHOSIS | BIAS | ORNIPRESSIN | EMPIRICAL-EVIDENCE | DOUBLE-BLIND | ALBUMIN | NORADRENALINE | GASTROENTEROLOGY & HEPATOLOGY | Vasoconstrictor Agents - therapeutic use | Randomized Controlled Trials as Topic - statistics & numerical data | Hepatorenal Syndrome - drug therapy | Humans | Confidence intervals | Drug therapy | Mortality | Hepatology
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3. Full Text Terlipressin and Albumin vs Albumin in Patients With Cirrhosis and Hepatorenal Syndrome: A Randomized Study
by Martín–Llahí, Marta and Pépin, Marie–Noëlle and Guevara, Mónica and Díaz, Fernando and Torre, Aldo and Monescillo, Alberto and Soriano, Germán and Terra, Carlos and Fábrega, Emilio and Arroyo, Vicente and Rodés, Juan and Ginès, Pere and TAHRS Investigators
Gastroenterology, ISSN 0016-5085, 2008, Volume 134, Issue 5, pp. 1352 - 1359
Background & Aims: Hepatorenal syndrome is common in patients with advanced cirrhosis and constitutes a major problem in liver transplantation. There is no... 
Gastroenterology and Hepatology | CONTROLLED CLINICAL-TRIAL | SURVIVAL | MULTICENTER | LIVER-TRANSPLANTATION | THERAPY | ASCITES | MANAGEMENT | ORNIPRESSIN | RENAL-FUNCTION | GASTROENTEROLOGY & HEPATOLOGY | FAILURE | United States - epidemiology | Injections, Intravenous | Follow-Up Studies | Humans | Middle Aged | Liver Cirrhosis - mortality | Male | Lypressin - analogs & derivatives | Kidney Function Tests | Dose-Response Relationship, Drug | Time Factors | Adult | Female | Retrospective Studies | Drug Therapy, Combination | Liver Cirrhosis - drug therapy | Lypressin - administration & dosage | Vasoconstrictor Agents - administration & dosage | Survival Rate - trends | Liver Cirrhosis - complications | Hepatorenal Syndrome - etiology | Albumins - administration & dosage | Treatment Outcome | Hepatorenal Syndrome - mortality | Shock, Septic | Hepatorenal Syndrome - drug therapy | Adolescent | Aged | Albumin | Medicine, Experimental | Medical research | Care and treatment | Liver cirrhosis | Analysis
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4. Full Text Terlipressin for hepatorenal syndrome
by Gluud, Lise Lotte and Christensen, Kurt and Christensen, Erik and Krag, Aleksander
Cochrane database of systematic reviews (Online), ISSN 1469-493X, 2012, Volume 9, Issue 9, p. CD005162
Background Clinical trials suggest that terlipressin improves renal function in hepatorenal syndrome, but the evidence concerning mortality is equivocal.... 
METAANALYSIS | Humans | PREVENTION | Lypressin [analogs & derivatives; therapeutic use] | RANDOMIZED CONTROLLED-TRIAL | SYNDROME HRS | Randomized Controlled Trials as Topic | Hepatorenal Syndrome [drug therapy] | MEDICINE, GENERAL & INTERNAL | Vasoconstrictor Agents [therapeutic use] | CIRRHOSIS | DOUBLE-BLIND | VASOPRESSIN | PLACEBO-CONTROLLED TRIAL | ALBUMIN | NORADRENALINE | Vasoconstrictor Agents - therapeutic use | Albumins - therapeutic use | Terlipressin | Hepatorenal Syndrome - drug therapy | Lypressin - therapeutic use | Hepatorenal Syndrome - classification | Lypressin - analogs & derivatives
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5. Full Text Predictors of response to therapy with terlipressin and albumin in patients with cirrhosis and type 1 hepatorenal syndrome
by Nazar, André and Pereira, Gustavo Henrique and Guevara, Mónica and Martín‐Llahi, Marta and Pepin, Marie‐Noëlle and Marinelli, Marcella and Solá, Elsa and Baccaro, María Eugenia and Terra, Carlos and Arroyo, Vicente and Ginès, Pere
Hepatology, ISSN 0270-9139, 01/2010, Volume 51, Issue 1, pp. 219 - 226
Terlipressin plus albumin is an effective treatment for type 1 hepatorenal syndrome (HRS), but approximately only half of the patients respond to this therapy.... 
SERUM CREATININE | PATHOGENESIS | SURVIVAL | CONTROLLED-TRIAL | PILOT | PRETRANSPLANT RENAL-FUNCTION | LIVER-TRANSPLANTATION | MANAGEMENT | NORADRENALINE | KIDNEY | GASTROENTEROLOGY & HEPATOLOGY | Liver Cirrhosis - drug therapy | Predictive Value of Tests | Humans | Middle Aged | Male | Antihypertensive Agents - therapeutic use | Lypressin - analogs & derivatives | Albumins - therapeutic use | Hepatorenal Syndrome - drug therapy | Lypressin - therapeutic use | Creatinine - blood | Female | Aged | Blood Pressure - drug effects | Liver cirrhosis
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6. Full Text Terlipressin given by continuous intravenous infusion versus intravenous boluses in the treatment of hepatorenal syndrome: A randomized controlled study
by Cavallin, Marta and Piano, Salvatore and Romano, Antonietta and Fasolato, Silvano and Frigo, Anna Chiara and Benetti, Gianpiero and Gola, Elisabetta and Morando, Filippo and Stanco, Marialuisa and Rosi, Silvia and Sticca, Antonietta and Cillo, Umberto and Angeli, Paolo
Hepatology, ISSN 0270-9139, 03/2016, Volume 63, Issue 3, pp. 983 - 992
In patients with cirrhosis and hepatorenal syndrome (HRS), terlipressin has been used either as continuous intravenous infusion or as intravenous boluses. To... 
TRIAL | CHRONIC LIVER-FAILURE | THERAPY | CIRRHOSIS | PREDICTORS | GASTROENTEROLOGY & HEPATOLOGY | PLUS ALBUMIN | Lypressin - administration & dosage | Vasoconstrictor Agents - administration & dosage | Vasoconstrictor Agents - adverse effects | Humans | Middle Aged | Male | Lypressin - analogs & derivatives | Hepatorenal Syndrome - mortality | Lypressin - adverse effects | Hepatorenal Syndrome - drug therapy | Female | Italy - epidemiology | Aged | Infusions, Intravenous | Antiretroviral drugs | Prescription drugs | Creatinine | Cirrhosis | Intravenous administration | Patients | Body weight
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7. Full Text Terlipressin and albumin for type-1 hepatorenal syndrome associated with sepsis
by Rodríguez, Ezequiel and Elia, Chiara and Solà, Elsa and Barreto, Rogelio and Graupera, Isabel and Andrealli, Alida and Pereira, Gustavo and Poca, Maria and Sánchez, Jordi and Guevara, Mónica and Soriano, Germán and Alessandria, Carlo and Fernández, Javier and Arroyo, Vicente and Ginès, Pere
Journal of Hepatology, ISSN 0168-8278, 2014, Volume 60, Issue 5, pp. 955 - 961
Background & Aims Terlipressin and albumin is the standard of care for classical type-1 hepatorenal syndrome (HRS) not associated with active infections.... 
Gastroenterology and Hepatology | Cirrhosis | Terlipressin | Acute-on-chronic liver failure | Hepatorenal syndrome | MANAGEMENT | METAANALYSIS | VASOCONSTRICTOR DRUGS | SPONTANEOUS BACTERIAL PERITONITIS | GELATINASE-ASSOCIATED LIPOCALIN | PATHOGENESIS | THERAPY | RENAL-FAILURE | GASTROENTEROLOGY & HEPATOLOGY | PLUS ALBUMIN | Blood Pressure | Heart Rate | Liver Failure - complications | Liver Failure - physiopathology | Prospective Studies | Liver Failure - drug therapy | Humans | Middle Aged | Male | Sepsis - complications | Treatment Outcome | Hepatorenal Syndrome - complications | Lypressin - analogs & derivatives | Hepatorenal Syndrome - physiopathology | Albumins - therapeutic use | Sepsis - drug therapy | Hepatorenal Syndrome - drug therapy | Lypressin - therapeutic use | Creatinine - blood | Female | Aged | Kidney - physiopathology | Albumin
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8. Full Text A Randomized, Prospective, Double-Blind, Placebo-Controlled Trial of Terlipressin for Type 1 Hepatorenal Syndrome
by Sanyal, Arun J and Boyer, Thomas and Garcia–Tsao, Guadalupe and Regenstein, Frederick and Rossaro, Lorenzo and Appenrodt, Beate and Blei, Andres and Gülberg, Veit and Sigal, Samuel and Teuber, Peter and Terlipressin Study Grp and Terlipressin Study Group
Gastroenterology, ISSN 0016-5085, 2008, Volume 134, Issue 5, pp. 1360 - 1368
Background & Aims: Hepatorenal syndrome (HRS) type 1 is a progressive functional renal failure in subjects with advanced liver disease. The aim of this study... 
Gastroenterology and Hepatology | PATHOGENESIS | LIVER-TRANSPLANTATION | ASCITES | PROGNOSIS | SPONTANEOUS BACTERIAL PERITONITIS | SAFE THERAPY | CIRRHOTIC-PATIENTS | ALBUMIN | WATER-RETENTION | GASTROENTEROLOGY & HEPATOLOGY | PREDICTIVE FACTORS | Severity of Illness Index | United States - epidemiology | Lypressin - administration & dosage | Vasoconstrictor Agents - administration & dosage | Injections, Intravenous | Prospective Studies | Double-Blind Method | Follow-Up Studies | Humans | Middle Aged | Male | Survival Rate | Treatment Outcome | Lypressin - analogs & derivatives | Hepatorenal Syndrome - mortality | Hepatorenal Syndrome - physiopathology | Germany - epidemiology | Kidney Function Tests | Dose-Response Relationship, Drug | Shock, Septic | Hepatorenal Syndrome - drug therapy | Female | Russia - epidemiology | Clinical trials | Analysis | Liver diseases
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9. Full Text Predictors of response to terlipressin plus albumin in hepatorenal syndrome (HRS) type 1: Relationship of serum creatinine to hemodynamics
by Boyer, Thomas D and Sanyal, Arun J and Garcia-Tsao, Guadalupe and Blei, Andres and Carl, Daniel and Bexon, Alice S and Teuber, Peter and Terlipressin Study Grp and Terlipressin Study Group
Journal of Hepatology, ISSN 0168-8278, 2010, Volume 55, Issue 2, pp. 315 - 321
Background & Aims Administration of terlipressin plus albumin is effective in reversing type 1 HRS as compared to albumin alone. However, only about 1/3 of... 
Gastroenterology and Hepatology | PATHOGENESIS | SURVIVAL | CONTROLLED-TRIAL | THERAPY | PROGNOSIS | CIRRHOSIS | REFRACTORY ASCITES | GASTROENTEROLOGY & HEPATOLOGY | Hepatorenal Syndrome - blood | Lypressin - administration & dosage | Vasoconstrictor Agents - administration & dosage | Prospective Studies | Double-Blind Method | Humans | Albumins - administration & dosage | Male | Hepatorenal Syndrome - classification | Lypressin - analogs & derivatives | Hepatorenal Syndrome - physiopathology | Hepatorenal Syndrome - drug therapy | Creatinine - blood | Adult | Female | Blood Pressure - drug effects | Hemodynamics - drug effects | Albumin | Analysis | Gastrointestinal diseases
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10. Full Text Terlipressin Plus Albumin Is More Effective Than Albumin Alone in Improving Renal Function in Patients With Cirrhosis and Hepatorenal Syndrome Type 1
by Boyer, Thomas D and Sanyal, Arun J and Wong, Florence and Frederick, R. Todd and Lake, John R and O’Leary, Jacqueline G and Ganger, Daniel and Jamil, Khurram and Pappas, Stephen Chris and REVERSE Study Investigators
Gastroenterology, ISSN 0016-5085, 2016, Volume 150, Issue 7, pp. 1579 - 1589.e2
Background & Aims Hepatorenal syndrome type 1 (HRS-1) in patients with cirrhosis and ascites is a functional, potentially reversible, form of acute kidney... 
Gastroenterology and Hepatology | Large-Volume Paracentesis | Acute Kidney Injury | Clinical Trial | REVERSE Study | DIAGNOSIS | TRIALS | METAANALYSIS | MANAGEMENT | TRANSPLANTATION | HEMODYNAMICS | CHRONIC LIVER-FAILURE | CREATININE | GASTROENTEROLOGY & HEPATOLOGY | Lypressin - administration & dosage | Vasoconstrictor Agents - administration & dosage | Kidney - drug effects | Liver Cirrhosis - complications | Hepatorenal Syndrome - etiology | Humans | Middle Aged | Albumins - administration & dosage | Male | Treatment Outcome | Lypressin - analogs & derivatives | Hepatorenal Syndrome - physiopathology | Kidney Function Tests | Canada | Hepatorenal Syndrome - drug therapy | Adult | Female | Drug Therapy, Combination | Kidney - physiopathology | Albumin | Care and treatment | Pharmaceutical industry | Liver cirrhosis
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11. Full Text Noradrenaline vs. terlipressin in the treatment of hepatorenal syndrome: A randomized study
by Singh, Virendra and Ghosh, Souvik and Singh, Baljinder and Kumar, Pradeep and Sharma, Navneet and Bhalla, Ashish and Sharma, A.K and Choudhary, N.S and Chawla, Yogesh and Nain, C.K
Journal of Hepatology, ISSN 0168-8278, 2012, Volume 56, Issue 6, pp. 1293 - 1298
Background & Aims Various vasoconstrictors are useful in the management of hepatorenal syndrome (HRS). Terlipressin is the drug of choice; however, it is... 
Gastroenterology and Hepatology | Splanchnic vasodilatation | Vasopressor | Ascites | Renal dysfunction | CONTROLLED-TRIAL | INDUCED CIRCULATORY DYSFUNCTION | PREVENTION | MIDODRINE | PILOT | PARACENTESIS | CIRRHOTIC-PATIENTS | GASTROENTEROLOGY & HEPATOLOGY | PREDICTIVE FACTORS | PLUS ALBUMIN | Norepinephrine - therapeutic use | Hepatorenal Syndrome - blood | Humans | Middle Aged | Male | Lypressin - analogs & derivatives | Hepatorenal Syndrome - physiopathology | Hepatorenal Syndrome - drug therapy | Lypressin - therapeutic use | Adult | Female | Aged | Blood Pressure - drug effects | Phenols | Medicine, Experimental | Medical research | Noradrenaline
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12. Full Text Review article: potential mechanisms of action of rifaximin in the management of hepatic encephalopathy and other complications of cirrhosis
by Bajaj, J. S
Alimentary Pharmacology & Therapeutics, ISSN 0269-2813, 01/2016, Volume 43, Issue S1, pp. 11 - 26
Summary Background Progressive gut milieu (microbiota) changes occur in patients with cirrhosis and are associated with complications [e.g. hepatic... 
HUMAN GUT MICROBIOME | LIVER-CIRRHOSIS | BILE-ACID | PROPHYLAXIS | BACTERIAL-INFECTIONS | LACTULOSE | DOUBLE-BLIND | RANDOMIZED-TRIAL | IMPROVES | PHARMACOLOGY & PHARMACY | PORTAL-SYSTEMIC ENCEPHALOPATHY | GASTROENTEROLOGY & HEPATOLOGY | Recurrence | Hypertension, Portal - complications | Liver Cirrhosis - complications | Humans | Peritonitis - complications | Esophageal and Gastric Varices - complications | Hepatic Encephalopathy - complications | Hepatic Encephalopathy - drug therapy | Hepatorenal Syndrome - complications | Hypertension, Portal - drug therapy | Ascites - drug therapy | Gastrointestinal Hemorrhage - complications | Gastrointestinal Microbiome - drug effects | Rifamycins - pharmacology | Rifamycins - therapeutic use | Hepatorenal Syndrome - drug therapy | Ascites - complications | Liver Diseases - complications | Disease Management | Liver Diseases - drug therapy | Peritonitis - drug therapy | Gastrointestinal Hemorrhage - drug therapy | Esophageal and Gastric Varices - drug therapy | Hypertension | Complications and side effects | Microbiota (Symbiotic organisms) | Physiological aspects | Carbohydrate metabolism | Fatty acids | Liver cirrhosis | Hepatic encephalopathy
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13. Full Text Terlipressin therapy with and without albumin for patients with hepatorenal syndrome: Results of a prospective, nonrandomized study
by Ortega, Rolando and Ginès, Pere and Uriz, Juan and Cárdenas, Andrés and Calahorra, Blas and De Las Heras, Dara and Guevara, Mónica and Bataller, Ramón and Jiménez, Wladimiro and Arroyo, Vicente and Rodés, Juan
Hepatology, ISSN 0270-9139, 10/2002, Volume 36, Issue 4 I, pp. 941 - 948
Vasopressin analogues associated with albumin improve renal function in hepatorenal syndrome (HRS). The current study was aimed at assessing the efficacy of... 
Recurrence | Lypressin - administration & dosage | Prospective Studies | Liver Cirrhosis - complications | Humans | Middle Aged | Antihypertensive Agents - administration & dosage | Albumins - administration & dosage | Male | Lypressin - analogs & derivatives | Hepatorenal Syndrome - mortality | Antihypertensive Agents - adverse effects | Lypressin - adverse effects | Hepatorenal Syndrome - drug therapy | Survival Analysis | Adult | Female | Aged | Drug Therapy, Combination
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