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Journal Article
Cancer, ISSN 0008-543X, 05/2017, Volume 123, Issue 10, pp. 1721 - 1730
BACKGROUND As panel testing becomes more common in clinical practice, it is important to understand the prevalence and trends associated with the pathogenic... 
breast cancer type 1 (BRCA1) | panel testing | hereditary breast and ovarian cancer | BRCA2 | triple‐negative breast cancer | triple-negative breast cancer | POPULATION | BRCA2 MUTATIONS | METAANALYSIS | VARIANTS | RISK | PREVALENCE | FAMILY-HISTORY | SUSCEPTIBILITY GENES | COWDEN-SYNDROME | ONCOLOGY | DIFFUSE GASTRIC-CANCER | Genetic Testing | Age Factors | Humans | Middle Aged | Young Adult | Checkpoint Kinase 2 - genetics | Tumor Suppressor Proteins - genetics | Aged, 80 and over | Genes, BRCA2 | Adult | Female | RNA Helicases - genetics | Lynch Syndrome II - genetics | Neoplastic Syndromes, Hereditary - genetics | Genes, BRCA1 | Nuclear Proteins - genetics | Fanconi Anemia Complementation Group N Protein | Hereditary Breast and Ovarian Cancer Syndrome - genetics | DNA-Binding Proteins - genetics | Fanconi Anemia Complementation Group Proteins | Breast Neoplasms - genetics | Triple Negative Breast Neoplasms - genetics | Aged | Ataxia Telangiectasia Mutated Proteins - genetics | Ubiquitin-Protein Ligases - genetics | Women | Breast cancer | Genetic aspects | Diagnosis | Research | Health aspects | Oncogenes | BRCA2 protein | CHK2 protein | Threonine | BRCA1 protein | Genes | Health risks | Protein C | Genetic screening | DNA helicase | Men | Breast | Ataxia | Ataxia telangiectasia mutated protein | Protein-serine/threonine kinase | Mutation | Health risk assessment | Age | Cancer
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 12/2016, Volume 160, Issue 3, pp. 393 - 410
Genetic evaluation is increasingly becoming an integral part of the management of women with newly diagnosed breast and ovarian cancer (OC), and of individuals... 
BRCA | Breast and ovarian cancer | Medicine & Public Health | Surveillance | Multiple-gene panel testing | Oncology | Cancer genetic counseling | Genetic counselors | LYNCH-SYNDROME | PEUTZ-JEGHERS-SYNDROME | REVISED BETHESDA GUIDELINES | CLINICAL CHARACTERISTICS | HEREDITARY COLORECTAL-CANCER | ONCOLOGY | INCREASED RISK | SOCIETY TASK-FORCE | ATM GENE | DIFFUSE GASTRIC-CANCER | BRCA2 MUTATION | Breast Neoplasms, Male - genetics | Hereditary Breast and Ovarian Cancer Syndrome - diagnosis | Humans | Male | Biomarkers, Tumor | Genetic Testing - methods | Breast Neoplasms - therapy | Ovarian Neoplasms - genetics | Hereditary Breast and Ovarian Cancer Syndrome - therapy | Genes, BRCA2 | Germ-Line Mutation | Female | Genes, BRCA1 | Stomach Neoplasms - genetics | Breast Neoplasms, Male - diagnosis | Hereditary Breast and Ovarian Cancer Syndrome - genetics | Genetic Predisposition to Disease | Stomach Neoplasms - diagnosis | Ovarian Neoplasms - prevention & control | Fanconi Anemia Complementation Group N Protein - genetics | Ovarian Neoplasms - diagnosis | Stomach Neoplasms - therapy | Penetrance | Breast Neoplasms - prevention & control | Breast Neoplasms - genetics | Breast Neoplasms, Male - therapy | Stomach Neoplasms - prevention & control | Ovarian Neoplasms - therapy | Breast Neoplasms - diagnosis | Disease Management | Mutation | Medical research | Care and treatment | Breast cancer | Disease susceptibility | Patients | Genetic screening | Ovarian cancer | Cancer patients | Risk assessment | Medicine, Experimental | Genetic aspects | Tumor proteins | Cancer
Journal Article
Nature, ISSN 0028-0836, 10/2018, Volume 562, Issue 7726, pp. 217 - 222
Journal Article
Cancer, ISSN 0008-543X, 07/2017, Volume 123, Issue 13, pp. 2497 - 2505
BACKGROUND Breast cancer (BC) disparities may widen with genomic advances. The authors compared non‐Hispanic white (NHW), black, and Hispanic BC survivors for... 
breast cancer | hereditary cancer | cancer risk management genetic testing | cancer disparities | MUTATION CARRIERS | HEREDITARY BREAST | OVARIAN-CANCER | FAMILY-HISTORY | AWARENESS | CARE | LATINAS | WOMEN | ONCOLOGY | NEW-YORK-CITY | HEALTH | Multivariate Analysis | Salpingectomy - statistics & numerical data | Hereditary Breast and Ovarian Cancer Syndrome - diagnosis | Humans | Middle Aged | Healthcare Disparities - ethnology | Hispanic Americans - statistics & numerical data | Ovarian Neoplasms - genetics | Hereditary Breast and Ovarian Cancer Syndrome - therapy | Ovariectomy - statistics & numerical data | Genes, BRCA2 | Adult | Female | Genes, BRCA1 | Prophylactic Surgical Procedures - statistics & numerical data | Ethnic Groups - statistics & numerical data | Hereditary Breast and Ovarian Cancer Syndrome - genetics | Ovarian Neoplasms - prevention & control | Risk Assessment | Genetic Testing - statistics & numerical data | Survivors | European Continental Ancestry Group - statistics & numerical data | Logistic Models | Breast Neoplasms - prevention & control | African Americans - statistics & numerical data | Prophylactic Mastectomy - statistics & numerical data | Breast Neoplasms - genetics | Heterozygote | Young women | Breast cancer | Genetic aspects | Health care disparities | Diagnosis | Management | Health aspects | Risk factors | Ovariectomy | Invasiveness | Test procedures | Health risks | Risk reduction | Risk | Population genetics | Genetic screening | Demographic variables | Current carriers | Demographics | Multilevel | Breast | Sampling methods | Mutation | Widening | Risk management | Health risk assessment | Hispanics | Cancer
Journal Article
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 7/2012, Volume 134, Issue 1, pp. 353 - 362
In spite the close association of the triple-negative breast cancer immunophenotype with hereditary breast cancers and the BRCA1 pathway, there is a lack of... 
Oncology | Hereditary breast–ovarian cancer | BRCA1 | Genetic testing | Medicine & Public Health | Triple-negative breast cancer | Hereditary breast-ovarian cancer | GENOMIC REARRANGEMENTS | FOUNDER MUTATIONS | ESTROGEN-RECEPTOR | PACLITAXEL | EPIRUBICIN | ONCOLOGY | RANDOMIZED PHASE-III | GERMLINE MUTATIONS | DENSE SEQUENTIAL CHEMOTHERAPY | YOUNG-WOMEN | CMF | Carcinoma, Ductal, Breast - genetics | Receptors, Estrogen - metabolism | Carcinoma, Ductal, Breast - epidemiology | Genetic Testing | Prevalence | Hereditary Breast and Ovarian Cancer Syndrome - diagnosis | Humans | Middle Aged | Receptor, ErbB-2 - metabolism | Carcinoma, Lobular - epidemiology | Hereditary Breast and Ovarian Cancer Syndrome - metabolism | Patient Selection | Receptors, Progesterone - metabolism | Young Adult | Carcinoma, Lobular - genetics | DNA Mutational Analysis | Aged, 80 and over | Adult | Female | Carcinoma, Ductal, Breast - metabolism | Hereditary Breast and Ovarian Cancer Syndrome - genetics | Carcinoma, Lobular - diagnosis | Carcinoma, Ductal, Breast - diagnosis | BRCA1 Protein - genetics | Heterozygote | Aged | Carcinoma, Lobular - metabolism | Hereditary Breast and Ovarian Cancer Syndrome - epidemiology | Mutation | BRCA mutations | Oncology, Experimental | Breast cancer | Research | Toy industry | Genetic screening | Prevalence studies (Epidemiology) | Ovarian cancer | Analysis | DNA | Genetic aspects | Diagnosis | Cancer
Journal Article
American Journal of Obstetrics and Gynecology, ISSN 0002-9378, 2017, Volume 217, Issue 5, pp. 512 - 521
The world of hereditary cancers has seen exponential growth in recent years. While hereditary breast and ovarian cancer and Lynch syndrome account for the... 
Obstetrics and Gynecology | BRCA | risk reduction | screening | ovarian cancer | high risk | endometrial cancer | hereditary cancer | cervical cancer | Lynch syndrome | BRCA2 MUTATION CARRIERS | LI-FRAUMENI SYNDROME | LYNCH-SYNDROME | COLORECTAL-CANCER SYNDROME | PEUTZ-JEGHERS-SYNDROME | RANDOMIZED-TRIAL | REDUCING SALPINGO-OOPHORECTOMY | FAMILIAL OVARIAN-CANCER | OBSTETRICS & GYNECOLOGY | GERMLINE MUTATIONS | Genetic Testing | DNA Polymerase III - genetics | Hereditary Breast and Ovarian Cancer Syndrome - diagnosis | Humans | Li-Fraumeni Syndrome - diagnosis | DNA Mismatch Repair - genetics | Tumor Suppressor Protein p53 - genetics | Genital Neoplasms, Female - diagnosis | Li-Fraumeni Syndrome - genetics | Epithelial Cell Adhesion Molecule - genetics | Genes, BRCA2 | Female | RNA Helicases - genetics | Lynch Syndrome II - genetics | Neoplastic Syndromes, Hereditary - genetics | Genes, BRCA1 | Genital Neoplasms, Female - genetics | Hereditary Breast and Ovarian Cancer Syndrome - genetics | PTEN Phosphohydrolase - genetics | Genetic Predisposition to Disease | Hamartoma Syndrome, Multiple - genetics | Fanconi Anemia Complementation Group Proteins - genetics | Protein-Serine-Threonine Kinases - genetics | Neoplastic Syndromes, Hereditary - diagnosis | MutS Homolog 2 Protein - genetics | DNA-Binding Proteins - genetics | Peutz-Jeghers Syndrome - genetics | Hamartoma Syndrome, Multiple - diagnosis | MutL Protein Homolog 1 - genetics | Peutz-Jeghers Syndrome - diagnosis | Lynch Syndrome II - diagnosis | Mismatch Repair Endonuclease PMS2 - genetics | Gene mutations | Endometrial cancer | Diagnosis | Cervical cancer | Genetic screening | Cancer | Ovarian cancer
Journal Article