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1. Full Text Genital Shedding of Herpes Simplex Virus Among Symptomatic and Asymptomatic Persons With HSV-2 Infection
by Tronstein, Elizabeth and Johnston, Christine and Huang, Meei-Li and Selke, Stacy and Magaret, Amalia and Warren, Terri and Corey, Lawrence and Wald, Anna
JAMA, ISSN 0098-7484, 04/2011, Volume 305, Issue 14, pp. 1441 - 1449
CONTEXT Since herpes simplex virus type 2 (HSV-2) antibody tests have become commercially available, an increasing number of persons have learned that they... 
UNITED-STATES | WOMEN | DIAGNOSIS | MEDICINE, GENERAL & INTERNAL | TYPE-2 INFECTION | TRANSMISSION | ACYCLOVIR | REACTIVATION | DNA | PREVENTION | PREVALENCE | Mucous Membrane - virology | Humans | Middle Aged | DNA, Viral - analysis | Male | Virus Shedding | Herpesvirus 2, Human | Herpes Genitalis - pathology | Herpes Genitalis - virology | Polymerase Chain Reaction | Adult | Female | Cohort Studies | Causes of | Herpes genitalis | Care and treatment | Usage | Diagnosis | Serodiagnosis | Medical tests | Urogenital system | Herpes viruses | Index Medicus | Abridged Index Medicus
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2. Full Text Lambda Interferon (IFN-λ), a Type III IFN, Is Induced by Viruses and IFNs and Displays Potent Antiviral Activity against Select Virus Infections In Vivo
by Nina Ank and Hans West and Christina Bartholdy and Kristina Eriksson and Allan R. Thomsen and Søren R. Paludan and Sahlgrenska akademin and Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning and Institute of Medicine, Department of Rheumatology and Inflammation Research and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
Journal of Virology, ISSN 0022-538X, 05/2006, Volume 80, Issue 9, pp. 4501 - 4509
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
CYTOKINES | VIROLOGY | DENDRITIC CELLS | ALPHA/BETA | CLONAL EXPANSION | GAMMA-INTERFERON | GENE-EXPRESSION | LYMPHOCYTIC CHORIOMENINGITIS VIRUS | HEPATITIS-C | VIRAL-INFECTION | CD8 T-CELLS | Lymphocytic choriomeningitis virus - immunology | Interferons - biosynthesis | Cardiovirus Infections - virology | Arenaviridae Infections - virology | Antiviral Agents - immunology | Humans | Interferons - immunology | Arenaviridae Infections - prevention & control | Herpes Genitalis - prevention & control | Herpes Genitalis - pathology | Female | Lymphocytic choriomeningitis virus - physiology | Interferons - genetics | Vagina - pathology | Encephalomyocarditis virus - physiology | Mice, Inbred C57BL | Encephalomyocarditis virus - immunology | Cardiovirus Infections - prevention & control | Disease Progression | Interferons - deficiency | Mice, Knockout | Animals | Herpesvirus 2, Human - immunology | Gene Expression Regulation, Viral | Herpes Genitalis - virology | Vagina - virology | Cell Line, Tumor | Mice | Index Medicus | Cellular Response to Infection | pathology | Interferons | Cardiovirus Infections | Viral | Mikrobiologi inom det medicinska området | genetics | Encephalomyocarditis virus | biosynthesis | Tumor | Arenaviridae Infections | immunology | Human | Cell Line | Gene Expression Regulation | physiology | Vagina | Antiviral Agents | prevention & control | Inbred C57BL | Knockout | Herpes Genitalis | Lymphocytic choriomeningitis virus | Microbiology in the medical area | deficiency | virology | Herpesvirus 2
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3. Full Text Efficacy Results of a Trial of a Herpes Simplex Vaccine
by Belshe, Robert B and Leone, Peter A and Bernstein, David I and Wald, Anna and Levin, Myron J and Stapleton, Jack T and Gorfinkel, Iris and Morrow, Rhoda L. Ashley and Ewell, Marian G and Stokes-Riner, Abbie and Dubin, Gary and Heineman, Thomas C and Schulte, Joann M and Deal, Carolyn D and Herpevac Trial Women and Herpevac Trial for Women
The New England Journal of Medicine, ISSN 0028-4793, 01/2012, Volume 366, Issue 1, pp. 34 - 43
There is no vaccine to prevent herpes simplex virus (HSV) infection. In this trial in 8323 women, a candidate HSV vaccine containing glycoprotein D was found... 
UNITED-STATES | MEDICINE, GENERAL & INTERNAL | SAFETY | GENITAL HERPES | INFECTION | SEROPREVALENCE | VIRUS TYPE-1 | EPIDEMIOLOGY | Double-Blind Method | Humans | Risk Factors | Viral Envelope Proteins | Genitalia, Female - virology | Male | Treatment Outcome | Virus Shedding | Herpes Simplex Virus Vaccines - immunology | Herpesvirus 2, Human | Herpesvirus 1, Human | Young Adult | Herpes Genitalis - prevention & control | Herpes Genitalis - virology | Adolescent | Herpes Simplex Virus Vaccines - adverse effects | Adult | Female | Prevention | Drugs | Control | Viral vaccines | Herpes simplex | Dosage and administration | Product/Service Evaluations | Drug therapy | Herpes simplex virus | Glycoprotein D | Hypersensitivity | Aluminum sulfate | Antibodies | Population studies | Infections | Vaccines | Lipid A | Hepatitis | Infectious diseases | Womens health | Monophosphoryl lipid A | Hepatitis A | Enzyme-linked immunosorbent assay | Index Medicus | Abridged Index Medicus
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4. Full Text Prevalence of Genital Human Papillomavirus Among Females in the United States, the National Health and Nutrition Examination Survey, 2003-2006
by Susan Hariri and Elizabeth R. Unger and Maya Sternberg and Eileen F. Dunne and David Swan and Sonya Patel and Lauri E. Markowitz
The Journal of Infectious Diseases, ISSN 0022-1899, 8/2011, Volume 204, Issue 4, pp. 566 - 573
Background. Genital human papillomaviruses (HPV) include >40 sexually transmitted viruses. Most HPV infections do not progress to disease, but infection with... 
Genitalia | Vaccination | Humans | Specimens | Infections | Preventive medicine | Epidemiology | Patient assessment | Health surveys | Age | VIRUSES | SQUAMOUS-CELL | INFECTIOUS DISEASES | MICROBIOLOGY | IMMUNOLOGY | CANCER | PNEUMOCOCCAL CONJUGATE VACCINE | WORLDWIDE | WOMEN | POLYMERASE-CHAIN-REACTION | DNA | DISEASE | INFECTION | HPV TYPES | United States - epidemiology | Prevalence | Nutrition Surveys | Middle Aged | Alphapapillomavirus - classification | Young Adult | Alphapapillomavirus - pathogenicity | Herpes Genitalis - virology | Adolescent | Uterine Cervical Neoplasms - virology | Adult | Female | Herpes Genitalis - epidemiology | Papillomaviruses | Surveys | Demographic aspects | Distribution | Index Medicus | Abridged Index Medicus
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5. Full Text Immune surveillance by CD8αα+ skin-resident T cells in human herpes virus infection
by Zhu, Jia and Peng, Tao and Johnston, Christine and Phasouk, Khamsone and Kask, Angela S and Klock, Alexis and Jin, Lei and Diem, Kurt and Koelle, David M and Wald, Anna and Robins, Harlan and Corey, Lawrence
Nature, ISSN 0028-0836, 2013, Volume 497, Issue 7450, pp. 494 - 497
Most herpes simplex virus 2 (HSV-2) reactivations in humans are subclinical and associated with rapid expansion and containment of virus. Previous studies have... 
Immunologic Surveillance | CD8-Positive T-Lymphocytes - cytology | Clone Cells - cytology | Skin - cytology | Humans | Receptors, Antigen, T-Cell, alpha-beta - immunology | Herpesvirus 2, Human - immunology | Herpes Genitalis - virology | Clone Cells - immunology | Adult | Receptors, Antigen, T-Cell, alpha-beta - metabolism | CD8-Positive T-Lymphocytes - immunology | Herpes Genitalis - immunology | Immunologic Memory - immunology | Skin - immunology | Index Medicus
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6. Full Text An estimate of the global prevalence and incidence of herpes simplex virus type 2 infection
by Looker, Katharine J and Garnett, Geoffrey P and Schmid, George P
Bulletin of the World Health Organization, ISSN 0042-9686, 10/2008, Volume 86, Issue 10, pp. 805 - 812
Objective To estimate the global prevalence and incidence of herpes simplex virus type 2 (HSV-2) infection in 2003. Methods A systematic review was undertaken... 
UNITED-STATES | TRANSMISSION | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | SEXUALLY-TRANSMITTED INFECTIONS | HIV-INFECTION | GENITAL-ULCER-DISEASE | HUMAN-IMMUNODEFICIENCY-VIRUS | SPREAD | HSV-2 INFECTION | DEVELOPING-COUNTRIES | AGE | Herpesvirus 2, Human - isolation & purification | Prevalence | Cross-Sectional Studies | Global Health | Humans | Middle Aged | Male | Incidence | Young Adult | Herpes Simplex - virology | Herpes Genitalis - virology | Adolescent | Adult | Female | Herpes Simplex - epidemiology | Herpes Genitalis - epidemiology | Index Medicus | Public Health Reviews
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7. Full Text Negative mucosal synergy between Herpes simplex type 2 and HIV in the female genital tract
by Rebbapragada, Anuradha and Wachihi, Charles and Pettengell, Christopher and Sunderji, Sherzana and Huibner, Sanja and Jaoko, Walter and Ball, Blake and Fowke, Keith and Mazzulli, Tony and Plummer, Francis A and Kaul, Rupert
AIDS, ISSN 0269-9370, 03/2007, Volume 21, Issue 5, pp. 589 - 598
Objective: There is substantial epidemiological evidence that infection by Herpes simplex virus type 2 (HSV2) enhances both HIV susceptibility and subsequent... 
Herpes simplex virus 2 | Mucosal immunity | Dendritic cells | Susceptibility | Transmission | AIDS/HIV | Genital mucosa | INFECTIOUS DISEASES | AFRICAN WOMEN | ACTIVATION | susceptibility | IMMUNOLOGY | HUMAN-IMMUNODEFICIENCY-VIRUS | CYTOMEGALOVIRUS | IMMATURE DENDRITIC CELLS | transmission | dendritic cells | VIROLOGY | DC-SIGN | REACTIVATION | genital mucosa | CHEMOKINE RECEPTOR | herpes simplex virus 2 | INFECTION | mucosal immunity | T-Lymphocyte Subsets - immunology | Herpes Genitalis - complications | Herpes Genitalis - transmission | Sex Work | Virus Shedding - immunology | Dendritic Cells - immunology | Humans | Middle Aged | Immunity, Mucosal | Vagina - immunology | Genitalia, Female - virology | HIV Infections - immunology | HIV-1 - isolation & purification | Adult | Female | HIV Infections - transmission | Herpes Genitalis - immunology | Cervix Uteri - virology | Cross-Sectional Studies | Genitalia, Female - immunology | HIV Infections - virology | Mucous Membrane - immunology | Herpes Genitalis - virology | Cervix Uteri - immunology | HIV Infections - complications | Vagina - virology | Chronic Disease | Index Medicus
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8. Full Text Virus-specific CD8+ T cells accumulate near sensory nerve endings in genital skin during subclinical HSV-2 reactivation
by Zhu, Jia and Koelle, David M and Cao, Jianhong and Vazquez, Julio and Meei, Li Huang and Hladik, Florian and Wald, Anna and Corey, Lawrence
Journal of Experimental Medicine, ISSN 0022-1007, 03/2007, Volume 204, Issue 3, pp. 595 - 603
Cytotoxic CD8(+) T cells play a critical role in controlling herpes simplex virus (HSV) infection and reactivation. However, little is known about the... 
MEDICINE, RESEARCH & EXPERIMENTAL | RESPONSES | HERPES-SIMPLEX-VIRUS | ACYCLOVIR | HIV | LATENCY | IMMUNOLOGY | PROTEINS | TYPE-2 | LESIONS | AUTOFLUORESCENCE | LYMPHOCYTES | Genitalia, Male - innervation | CD8-Positive T-Lymphocytes - pathology | Nerve Endings - immunology | Humans | Middle Aged | Male | Skin Diseases, Viral - virology | Genitalia, Female - innervation | Skin Diseases, Viral - immunology | Cell Movement - immunology | Herpesvirus 2, Human - immunology | Herpes Genitalis - pathology | Nerve Endings - virology | CD8-Positive T-Lymphocytes - virology | Herpes Genitalis - virology | Skin Diseases, Viral - pathology | Adult | Female | CD8-Positive T-Lymphocytes - immunology | Herpes Genitalis - immunology | Virus Activation - immunology | Nerve Endings - pathology | Index Medicus
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9. Full Text Reduction of HIV-1 RNA Levels with Therapy to Suppress Herpes Simplex Virus
by Nagot, Nicolas and Ouédraogo, Abdoulaye and Foulongne, Vincent and Konaté, Issouf and Weiss, Helen A and Vergne, Laurence and Defer, Marie-Christine and Djagbaré, Didier and Sanon, Anselme and Andonaba, Jean-Baptiste and Becquart, Pierre and Segondy, Michel and Vallo, Roselyne and Sawadogo, Adrien and Van de Perre, Philippe and Mayaud, Philippe and ANRS 1285 Study Grp and ANRS 1285 Study Group
The New England Journal of Medicine, ISSN 0028-4793, 02/2007, Volume 356, Issue 8, pp. 790 - 799
Coinfection with herpes simplex virus type 2 (HSV-2) in women with HIV-1 infection is associated with increased genital shedding of HIV-1 RNA. In this... 
CONTROLLED-TRIAL | MEDICINE, GENERAL & INTERNAL | AFRICAN WOMEN | TRANSMISSION | ACQUISITION | MEN | COMPARTMENTALIZATION | SEX WORKERS | HUMAN-IMMUNODEFICIENCY-VIRUS | TYPE-1 INFECTION | GENITAL-TRACT | Herpesvirus 2, Human - isolation & purification | Herpes Genitalis - complications | Acyclovir - therapeutic use | Virus Shedding - drug effects | Humans | RNA, Viral - blood | Herpes Genitalis - drug therapy | Viral Load | HIV-1 - physiology | HIV-1 - isolation & purification | Adult | Female | Virus Replication - drug effects | Antiviral Agents - pharmacology | Cervix Uteri - virology | Acyclovir - analogs & derivatives | Antiviral Agents - therapeutic use | HIV-1 - drug effects | HIV Infections - virology | Valine - analogs & derivatives | Acyclovir - pharmacology | RNA, Viral - analysis | Herpes Genitalis - virology | Adolescent | HIV Infections - complications | Valine - therapeutic use | Herpesvirus 2, Human - physiology | Valine - pharmacology | Care and treatment | Genetic aspects | HIV (Viruses) | Herpes simplex virus | Acquired immune deficiency syndrome--AIDS | Drug therapy | Womens health | Human immunodeficiency virus--HIV | Index Medicus | Abridged Index Medicus
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10. Full Text Rapid host immune response and viral dynamics in herpes simplex virus-2 infection
by Schiffer, Joshua T and Corey, Lawrence
Nature Medicine, ISSN 1078-8956, 03/2013, Volume 19, Issue 3, pp. 280 - 290
Herpes simplex virus-2 (HSV-2) is periodically shed throughout the human genital tract. Although a high viral load correlates with the development of genital... 
MEDICINE, RESEARCH & EXPERIMENTAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | GUINEA-PIGS | CD8(+) T-CELLS | LASER-CAPTURE MICRODISSECTION | CELL BIOLOGY | PLASMACYTOID DENDRITIC CELLS | TYPE-2 INFECTION | LYMPHOCYTE-ASSOCIATED ANTIGEN | LATENCY-ASSOCIATED TRANSCRIPT | HUMAN TRIGEMINAL GANGLIA | NF-KAPPA-B | RECURRENT GENITAL HERPES | Herpes Genitalis - transmission | Ganglia - virology | Mucous Membrane - virology | Antiviral Agents - therapeutic use | Herpesvirus Vaccines - immunology | Virus Latency | Humans | Seroepidemiologic Studies | Virus Shedding | Herpes Genitalis - drug therapy | Viral Load | Herpesvirus 2, Human - immunology | Mucous Membrane - immunology | Virus Replication | Herpes Genitalis - virology | Immunotherapy | Reproductive Tract Infections - immunology | Reproductive Tract Infections - virology | Herpesvirus 2, Human - physiology | Herpes Genitalis - immunology | Virus Activation | Prevention | Immune response | Distribution | Peptic ulcer | Genetic aspects | Research | Health aspects | Herpes simplex virus | Risk factors | Medical research | Sexually transmitted diseases--STD | Herpes viruses | Index Medicus
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11. Full Text Therapeutic Vaccine for Genital Herpes Simplex Virus-2 Infection: Findings From a Randomized Trial
by Bernstein, David I and Wald, Anna and Warren, Terri and Fife, Kenneth and Tyring, Stephen and Lee, Patricia and Van Wagoner, Nick and Magaret, Amalia and Flechtner, Jessica B and Tasker, Sybil and Chan, Jason and Morris, Amy and Hetherington, Seth
The Journal of Infectious Diseases, ISSN 0022-1899, 03/2017, Volume 215, Issue 6, pp. 856 - 864
Abstract Background. Genital herpes simplex virus type 2 (HSV-2) infection causes recurrent lesions and frequent viral shedding. GEN-003 is a candidate... 
Herpes simplex virus type 2 infection | Genital herpes | Therapeutic vaccine | Immunotherapy | GEN-003 | therapeutic vaccine | INFECTIOUS DISEASES | herpes simplex virus type 2 infection | TRANSMISSION | immunotherapy | RISK | MICROBIOLOGY | IMMUNOLOGY | TYPE-2 | Viral Vaccines - therapeutic use | Immunoglobulin G - blood | Humans | Middle Aged | Male | Virus Shedding | Viral Vaccines - adverse effects | Antibodies, Viral - blood | Herpes Genitalis - drug therapy | Young Adult | Herpes Genitalis - prevention & control | Herpesvirus 2, Human - immunology | Herpes Genitalis - virology | Adolescent | Adult | Female | Herpes Genitalis - immunology | Viral Vaccines - immunology | Index Medicus | Abridged Index Medicus
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12. Full Text Development of disease and immunity at the genital epithelium following intrarectal inoculation of male guinea pigs with herpes simplex virus type 2
by Bourne, Nigel and Banasik, Brianne N and Perry, Clarice L and Miller, Aaron L and White, Mellodee and Pyles, Richard B and Milligan, Gregg N
Virology, ISSN 0042-6822, 01/2019, Volume 526, pp. 180 - 188
Most analyses of genital immunity to herpes simplex virus type 2 (HSV-2) have been performed in females, consequently immune protection of the male genital... 
IFNγ | Male guinea pig | Foreskin | Perineum | Gene expression | Microarray | HSV-2 | NEGATIVE MEN | ACQUISITION | VACCINE | SEX | IFN gamma | RISK | CD8(+) T-CELLS | VIROLOGY | INFECTION | MICE | SENSORY GANGLIA | LYMPHOCYTES | Perineum - pathology | Foreskin - virology | Gene Expression | Guinea Pigs | Male | Foreskin - pathology | Genitalia, Male - pathology | Virus Shedding | Perineum - virology | T-Lymphocytes - virology | Animals | Foreskin - immunology | Herpesvirus 2, Human - immunology | Herpes Genitalis - pathology | Genitalia, Male - immunology | Herpes Genitalis - virology | Antibodies, Viral - immunology | T-Lymphocytes - immunology | Herpesvirus 2, Human - physiology | Genitalia, Male - virology | Herpes Genitalis - immunology | Cytokines - genetics | Disease Models, Animal | Viral antibodies | Microbiology | Analysis | Genes | Antibodies | Herpes simplex | T cells | Epithelium | Herpes simplex virus | Index Medicus
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