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Journal Article
Science, ISSN 0036-8075, 9/2007, Volume 317, Issue 5844, pp. 1522 - 1527
Some Toll and Toll-like receptors (TLRs) provide immunity to experimental infections in animal models, but their contribution to host defense in natural... 
T lymphocytes | Double stranded RNA | Memory interference | Cell lines | Central nervous system | Fibroblasts | Human herpesvirus 1 | Viruses | Infections | Research Articles | Genetic mutation | TOLL-LIKE RECEPTOR-3 | DOUBLE-STRANDED-RNA | INTERFERON | VIRUS-INFECTION | NK CELLS | GENE | RECOGNITION | IMMUNE-RESPONSES | MULTIDISCIPLINARY SCIENCES | EXPRESSION | T-LYMPHOCYTES | Interferons - biosynthesis | Encephalitis, Herpes Simplex - immunology | Dendritic Cells - immunology | Humans | Child, Preschool | Infant | Herpesvirus 1, Human - physiology | Genes, Dominant | Toll-Like Receptor 3 - deficiency | Leukocytes, Mononuclear - immunology | Killer Cells, Natural - immunology | Encephalitis, Herpes Simplex - genetics | Female | Toll-Like Receptor 3 - genetics | Fibroblasts - metabolism | Fibroblasts - virology | Cell Line | Poly I-C - pharmacology | Immunity, Innate | Keratinocytes - immunology | Toll-Like Receptor 3 - physiology | Alleles | Fibroblasts - immunology | Heterozygote | Toll-Like Receptor 3 - chemistry | Mutation | CD8-Positive T-Lymphocytes - immunology | Receptors | Research | Immunity | Health aspects | Herpes simplex encephalitis | Encephalitis | Infectious diseases | Immunology | Gene expression | Herpes viruses | Encephalitis, Herpes Simplex | Toll-Like Receptor 3 | Killer Cells, Natural | Dendritic Cells | Interferons | Keratinocytes | Leukocytes, Mononuclear | Immunity, Natural | Herpesvirus 1, Human | CD8-Positive T-Lymphocytes | Life Sciences | Poly I-C
Journal Article
Journal Article
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 2015, Volume 61, Issue 5, pp. 683 - 691
Background. Despite the proven efficacy of acyclovir (ACV) therapy, herpes simplex encephalitis (HSE) continues to cause substantial morbidity and mortality.... 
Encephalitis | Antiviral therapy | Valacyclovir | Acyclovir | Herpes simplex virus | ADULT PATIENTS | DIAGNOSIS | INFECTIOUS DISEASES | MULTICENTER | MANAGEMENT | COMBINATION THERAPY | MICROBIOLOGY | IMMUNOLOGY | CEREBROSPINAL-FLUID | herpes simplex virus | ACYCLOVIR THERAPY | POLYMERASE-CHAIN-REACTION | encephalitis | VIRUS-ENCEPHALITIS | acyclovir | CENTRAL-NERVOUS-SYSTEM | antiviral therapy | valacyclovir | Acyclovir - therapeutic use | Follow-Up Studies | Acyclovir - analogs & derivatives | Antiviral Agents - therapeutic use | Humans | Middle Aged | Valine - analogs & derivatives | Male | Encephalitis, Herpes Simplex - epidemiology | Valine - administration & dosage | Antiviral Agents - administration & dosage | Young Adult | Encephalitis, Herpes Simplex - physiopathology | Cognition Disorders | Adolescent | Aged, 80 and over | Encephalitis, Herpes Simplex - drug therapy | Quality of Life | Adult | Female | Valine - therapeutic use | Aged | Acyclovir - administration & dosage | Treatment outcome | Dosage and administration | Drug therapy | Analysis | and Commentaries | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Infektionsmedicin | Immunologi inom det medicinska området | Klinisk medicin | Mikrobiologi inom det medicinska området | Clinical Medicine | Microbiology in the medical area | Medicinska och farmaceutiska grundvetenskaper | Infectious Medicine | Immunology in the medical area
Journal Article
The Lancet Neurology, ISSN 1474-4422, 09/2018, Volume 17, Issue 9, pp. 733 - 735
There have been substantial advances in the recognition and treatment of autoimmune causes of encephalitis, particularly encephalitis associated with... 
RELAPSE | CLINICAL NEUROLOGY | ASPARTATE RECEPTOR ANTIBODIES | Encephalitis, Herpes Simplex | Encephalitis | Prospective Studies | Hashimoto Disease | Humans | Risk Factors | Retrospective Studies | Antigens | Immunoglobulins | Laboratories | Pathogenesis | Herpes viruses | Herpes simplex | Autoimmune diseases | Patients
Journal Article
by Armangue, Thaís and Spatola, Marianna and Vlagea, Alexandru and Mattozzi, Simone and Cárceles-Cordon, Marc and Martinez-Heras, Eloy and Llufriu, Sara and Muchart, Jordi and Erro, María Elena and Abraira, Laura and Moris, German and Monros-Giménez, Luis and Corral-Corral, Íñigo and Montejo, Carmen and Toledo, Manuel and Bataller, Luis and Secondi, Gabriela and Ariño, Helena and Martínez-Hernández, Eugenia and Juan, Manel and Marcos, Maria Angeles and Alsina, Laia and Saiz, Albert and Rosenfeld, Myrna R and Graus, Francesc and Dalmau, Josep and Aguilera-Albesa, Sergio and Amado-Puentes, Alfonso and Arjona-Padillo, Antonio and Arrabal, Luisa and Arratibel, Izascun and Aznar-Laín, Gemma and Bellas-Lamas, Paula and Bermejo, Teresa and Boyero-Durán, Sabas and Camacho, Ana and Campo, Andrea and Campos, Dulce and Cantarín-Extremera, Verónica and Carnero, Cristóbal and Conejo-Moreno, David and Dapena, Marta and Dacruz-Álvarez, David and Delgadillo-Chilavert, Verónica and Deyà, Angela and Estela-Herrero, Jordi and Felipe, Anna and Fernández-Cooke, Elisa and Fernández-Ramos, Joaquín and Fortuny, Claudia and García-Monco, Juan C and Gili, Teresa and González-Álvarez, Verónica and Guerri, Robert and Guillén, Sara and Hedrera-Fernández, Antonio and López, María and López-Laso, Eduardo and Lorenzo-Ruiz, María and Madruga, Marcos and Málaga-Diéguez, Ignacio and Martí-Carrera, Itxaso and Martínez-Lacasa, Xavier and Martín-Viota, Lucía and Martín Gil, Leticia and Martínez-González, María-Jesús and Moreira, Antia and Miranda-Herrero, María C and Monge, Lorena and Muñoz-Cabello, Beatriz and Navarro-Morón, Juan and Neth, Olaf and Noguera-Julian, Antoni and Nuñez-Enamorado, Noemí and Pomar, Virginia and Portillo-Cuenca, Juan C and Poyato, María and Prieto, Luis and Querol, Luis and Rodríguez-Rodríguez, Eloy and Sarria-Estrada, Silvana and Sierra, Concepción and Soler-Palacín, Pere and Soto-Insuga, Víctor and Toledo-Bravo, Laura and Tomás, Miguel and Torres-Torres, Carmen and Turón, Eulàlia and Zabalza, Ana and Spanish Herpes Simplex and Spanish Herpes Simplex Encephalitis Study Group
The Lancet Neurology, ISSN 1474-4422, 09/2018, Volume 17, Issue 9, pp. 760 - 772
Herpes simplex encephalitis can trigger autoimmune encephalitis that leads to neurological worsening. We aimed to assess the frequency, symptoms, risk factors,... 
ANTIBODIES | STROKE | RELAPSE | VIRUS ENCEPHALITIS | SERIES | ADULTS | D-ASPARTATE RECEPTOR | CLINICAL NEUROLOGY | CHILDREN | Autoantibodies - metabolism | Encephalitis, Herpes Simplex - diagnostic imaging | Encephalitis - diagnostic imaging | Humans | Middle Aged | Child, Preschool | Male | Encephalitis, Herpes Simplex - epidemiology | Encephalitis, Herpes Simplex - complications | Young Adult | Hashimoto Disease - epidemiology | Statistics, Nonparametric | Adult | Female | Child | Receptors, N-Methyl-D-Aspartate - immunology | Hashimoto Disease - etiology | Encephalitis - epidemiology | Encephalitis, Herpes Simplex - cerebrospinal fluid | Risk Factors | Rats | Hippocampus - pathology | Hashimoto Disease - diagnostic imaging | Hippocampus - metabolism | Magnetic Resonance Imaging | Animals | Adolescent | Encephalitis - cerebrospinal fluid | Glutamate Decarboxylase - metabolism | Aged | Hashimoto Disease - cerebrospinal fluid | Cohort Studies | Encephalitis - etiology | Demography | Glutamic acid receptors (ionotropic) | Epilepsy | Herpes simplex | Antibodies | Glutamic acid receptors | Risk factors | Apathy | Psychosis | Immunotherapy | Dysphagia | Amnesia | Children | Age | Seizures | Encephalitis | Antigens | Immunoglobulins | Consciousness | N-Methyl-D-aspartic acid receptors | Regression analysis | Patients | Choreoathetosis | Infectious diseases | Insomnia | Herpes viruses | Autoimmune diseases | Viral infections
Journal Article