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1. Full Text MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs
by Umbach, Jennifer Lin and Cullen, Bryan R and Karnowski, Heather W and Kramer, Martha F and Coen, Donald M and Jurak, Igor
Nature, ISSN 0028-0836, 08/2008, Volume 454, Issue 7205, pp. 780 - 783
Herpesviruses are characterized by their ability to maintain life-long latent infections in their animal hosts. However, the mechanisms that allow... 
CELLS | HERPES-SIMPLEX-VIRUS | NEURONAL SURVIVAL | REACTIVATION | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | ICP0 | TRANSCRIPT | READING-FRAME-P | TYPE-1 LATENCY | SENSORY NEURONS | Cell Line | RNA Processing, Post-Transcriptional | Down-Regulation | Genome, Viral - genetics | Humans | Immediate-Early Proteins - biosynthesis | RNA, Messenger - genetics | Male | MicroRNAs - metabolism | RNA, Messenger - metabolism | Ubiquitin-Protein Ligases - biosynthesis | Virus Latency - physiology | Herpesvirus 1, Human - physiology | Animals | Immediate-Early Proteins - genetics | RNA, Viral - genetics | Gene Expression Regulation, Viral | Base Sequence | Herpesvirus 1, Human - genetics | Mice | MicroRNAs - genetics | RNA, Viral - metabolism | Ubiquitin-Protein Ligases - genetics | Virus Latency - genetics | Messenger RNA | Herpesvirus diseases | Herpes | Genetic aspects | Properties | Health aspects | Herpes simplex virus | Gene expression
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2. Full Text Replication of ICP0-Null Mutant Herpes Simplex Virus Type 1 Is Restricted by both PML and Sp100
by Roger D. Everett and Carlos Parada and Philippe Gripon and Hüseyin Sirma and Anne Orr
Journal of Virology, ISSN 0022-538X, 03/2008, Volume 82, Issue 6, pp. 2661 - 2672
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
PROMOTER ACTIVITY | HISTONE DEACETYLATION | NUCLEAR-BODIES | LATENT INFECTION | VIROLOGY | EARLY GENE-EXPRESSION | REGULATORY PROTEIN | HUMAN FIBROBLASTS | NEURONAL CELLS | IMMEDIATE-EARLY GENE-1 | MEDIATED REPRESSION | Cell Line | Gene Expression | Transcription Factors - physiology | Immediate-Early Proteins - physiology | Humans | Neoplasm Proteins - physiology | Antigens, Nuclear - physiology | Viral Plaque Assay | DNA Primers | Ubiquitin-Protein Ligases - physiology | Autoantigens - physiology | Microscopy, Confocal | Tumor Suppressor Proteins - physiology | Herpesvirus 1, Human - physiology | Immediate-Early Proteins - genetics | Virus Replication | Base Sequence | Fluorescent Antibody Technique | Herpesvirus 1, Human - genetics | Nuclear Proteins - physiology | Mutation | Ubiquitin-Protein Ligases - genetics | Promyelocytic Leukemia Protein | Splenomegaly | Middle Aged | Male | Immediate-Early Proteins | Life Sciences | Leukemia, T-Cell | Antigens, Nuclear | Neoplasm Proteins | Receptors, Antigen, T-Cell, alpha-beta | Aged, 80 and over | Adult | Female | Clone Cells | Leukopenia | Autoantigens | Immunophenotyping | Herpesvirus 1, Human | Nuclear Proteins | Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor | Virology | Ubiquitin-Protein Ligases | Microbiology and Parasitology | Autoimmune Diseases | Receptors, Antigen, T-Cell, gamma-delta | Aged | Transcription Factors | Tumor Suppressor Proteins | Virus-Cell Interactions
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3. Full Text Herpes Simplex Virus Suppresses Necroptosis in Human Cells
by Guo, Hongyan and Omoto, Shinya and Harris, Philip A and Finger, Joshua N and Bertin, John and Gough, Peter J and Kaiser, William J and Mocarski, Edward S
Cell Host & Microbe, ISSN 1931-3128, 02/2015, Volume 17, Issue 2, pp. 243 - 251
Herpes simplex virus (HSV)-1 and HSV-2 are significant human pathogens causing recurrent disease. During infection, HSV modulates cell death pathways using the... 
APOPTOSIS | KAPPA-B ACTIVATION | MIXED LINEAGE KINASE | PROGRAMMED NECROSIS | DOMAIN-LIKE | MICROBIOLOGY | DEATH | MURINE CYTOMEGALOVIRUS | RIBONUCLEOTIDE REDUCTASE | VIROLOGY | RECEPTOR-INTERACTING PROTEIN | RIP3 | PARASITOLOGY | Humans | Caspase 8 - metabolism | Viral Proteins - metabolism | Host-Pathogen Interactions | Herpesvirus 1, Human - physiology | Herpesvirus 2, Human - immunology | Immune Evasion | Virus Replication | Cell Death | Ribonucleotide Reductases - metabolism | Herpesvirus 1, Human - immunology | Herpesvirus 2, Human - physiology | Receptor-Interacting Protein Serine-Threonine Kinases - antagonists & inhibitors | Nuclear Pore Complex Proteins - antagonists & inhibitors | RNA-Binding Proteins - antagonists & inhibitors | Proteins | Herpes simplex | Health aspects | Cells | Herpes simplex virus | ripoptosome | necrosome | herpesvirus | cell extrinsic death | host defense
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4. Full Text Cells infected with herpes simplex virus 1 export to uninfected cells exosomes containing STING, viral mRNAs, and microRNAs
by Maria Kalamvoki and Te Du and Bernard Roizman
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 11/2014, Volume 111, Issue 46, pp. E4991 - E4996
STING (stimulator of IFN genes) activates the IFN-dependent innate immune response to infection on sensing the presence of DNA in cytosol. The quantity of... 
microRNAs | IMMUNE-RESPONSE | VIRIONS | VESICLES | MULTIDISCIPLINARY SCIENCES | STABILIZES | ESTABLISHES | tetraspanins | ENDOSOMES | TRANSMISSION | INTERCELLULAR COMMUNICATION | exosomes | GENE-EXPRESSION | ICP0 | STING | herpes simplex viruses | Exosomes - metabolism | Tetraspanin 29 - analysis | Immunoprecipitation | Humans | Virulence | Cercopithecus aethiops | Cell Communication - physiology | MicroRNAs - metabolism | RNA, Messenger - metabolism | Membrane Proteins - deficiency | Herpesvirus 1, Human - physiology | Biological Transport | Viral Proteins - physiology | Membrane Proteins - metabolism | RNA, Viral - metabolism | Vero Cells | Virus Activation | Fibroblasts - metabolism | Fibroblasts - virology | Cellular Microenvironment | Viral Proteins - genetics | Herpes Simplex - virology | Animals | Virion - isolation & purification | Virus Replication | Cell Line, Tumor | Herpes Simplex - transmission | Herpesvirus 1, Human - genetics | Exosomes - chemistry | Cell Line, Transformed | Herpesvirus 1, Human - pathogenicity | Host-Pathogen Interactions - physiology | Biological Sciences | PNAS Plus
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5. Full Text TLR3 Deficiency in Patients with Herpes Simplex Encephalitis
by Shen-Ying Zhang and Emmanuelle Jouanguy and Sophie Ugolini and Asma Smahi and Gaëlle Elain and Pedro Romero and David Segal and Vanessa Sancho-Shimizu and Lazaro Lorenzo and Anne Puel and Capucine Picard and Ariane Chapgier and Sabine Plancoulaine and Matthias Titeux and Céline Cognet and Horst von Bernuth and Cheng-Lung Ku and Armanda Casrouge and Xin-Xin Zhang and Luis Barreiro and Joshua Leonard and Claire Hamilton and Pierre Lebon and Bénédicte Héron and Louis Vallée and Lluis Quintana-Murci and Alain Hovnanian and Flore Rozenberd and Eric Vivier and Frédéric Geissmann and Marc Tardieu and Laurent Abel and Jean-Laurent Casanova
Science, ISSN 0036-8075, 9/2007, Volume 317, Issue 5844, pp. 1522 - 1527
Some Toll and Toll-like receptors (TLRs) provide immunity to experimental infections in animal models, but their contribution to host defense in natural... 
T lymphocytes | Double stranded RNA | Memory interference | Cell lines | Central nervous system | Fibroblasts | Human herpesvirus 1 | Viruses | Infections | Research Articles | Genetic mutation | TOLL-LIKE RECEPTOR-3 | DOUBLE-STRANDED-RNA | INTERFERON | VIRUS-INFECTION | NK CELLS | GENE | RECOGNITION | IMMUNE-RESPONSES | MULTIDISCIPLINARY SCIENCES | EXPRESSION | T-LYMPHOCYTES | Interferons - biosynthesis | Encephalitis, Herpes Simplex - immunology | Dendritic Cells - immunology | Humans | Child, Preschool | Infant | Herpesvirus 1, Human - physiology | Genes, Dominant | Toll-Like Receptor 3 - deficiency | Leukocytes, Mononuclear - immunology | Killer Cells, Natural - immunology | Encephalitis, Herpes Simplex - genetics | Female | Toll-Like Receptor 3 - genetics | Fibroblasts - metabolism | Fibroblasts - virology | Cell Line | Poly I-C - pharmacology | Immunity, Innate | Keratinocytes - immunology | Toll-Like Receptor 3 - physiology | Alleles | Fibroblasts - immunology | Heterozygote | Toll-Like Receptor 3 - chemistry | Mutation | CD8-Positive T-Lymphocytes - immunology | Receptors | Research | Immunity | Health aspects | Herpes simplex encephalitis | Encephalitis | Infectious diseases | Immunology | Gene expression | Herpes viruses | Encephalitis, Herpes Simplex | Toll-Like Receptor 3 | Killer Cells, Natural | Dendritic Cells | Interferons | Keratinocytes | Leukocytes, Mononuclear | Immunity, Natural | Herpesvirus 1, Human | CD8-Positive T-Lymphocytes | Life Sciences | Poly I-C
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6. Full Text Herpes Simplex Virus 1 Infection Induces Activation and Subsequent Inhibition of the IFI16 and NLRP3 Inflammasomes
by Karen E. Johnson and Leela Chikoti and Bala Chandran
Journal of Virology, ISSN 0022-538X, 05/2013, Volume 87, Issue 9, pp. 5005 - 5018
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
AIM2 INFLAMMASOME | INTERFERON-INDUCIBLE PROTEIN | VIROLOGY | SIGNALING PATHWAY | GENE-EXPRESSION | HOST-DEFENSE | HIN-200 FAMILY | ICP0 PROTEIN | TYPE-1 INFECTION | UBIQUITIN LIGASES | VIRAL-INFECTION | Phosphoproteins - immunology | Cell Line | NLR Family, Pyrin Domain-Containing 3 Protein | Down-Regulation | Humans | Interleukin-1beta - immunology | Interleukin-1beta - genetics | Phosphoproteins - genetics | Nuclear Proteins - immunology | Herpes Simplex - genetics | Inflammasomes - genetics | Herpes Simplex - immunology | Carrier Proteins - genetics | Herpes Simplex - virology | Herpesvirus 1, Human - physiology | Inflammasomes - immunology | Herpesvirus 1, Human - genetics | Nuclear Proteins - genetics | Carrier Proteins - immunology | Virus-Cell Interactions
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7. Full Text Advances in viral transneuronal tracing
by Ugolini, Gabriella
Journal of Neuroscience Methods, ISSN 0165-0270, 12/2010, Volume 194, Issue 1, pp. 2 - 20
Powerful transneuronal tracing technologies exploit the ability of some neurotropic viruses to travel across neuronal pathways and to function as... 
Herpes Simplex | Transneuronal | Receptors | Pseudorabies | Rabies | Primates | Chemical synapses | Axonal transport | RETROGRADE AXONAL-TRANSPORT | RAT VISUAL-SYSTEM | STREET RABIES VIRUS | BIOCHEMICAL RESEARCH METHODS | TO-CELL SPREAD | NEUROSCIENCES | SYMPATHETIC PREGANGLIONIC NEURONS | PRIMARY MOTOR CORTEX | HERPES-SIMPLEX-VIRUS | DYNEIN LIGHT-CHAIN | CENTRAL-NERVOUS-SYSTEM | STRAND RNA VIRUSES | Neurons - virology | Rabies virus - physiology | Humans | Herpesvirus 1, Suid - physiology | Neuroanatomy - methods | Viruses | Nerve Net - physiology | Herpesvirus 1, Human - physiology | Rabies virus - genetics | Animals | Herpesviridae - physiology | Herpesviridae - genetics | Nerve Net - virology | Neurons - physiology | Herpesvirus 1, Human - genetics | Herpesvirus 1, Suid - genetics | Life Sciences | Neurons and Cognition
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8. Full Text Analysis of Human Alphaherpesvirus MicroRNA Expression in Latently Infected Human Trigeminal Ganglia
by Jennifer L. Umbach and Maria A. Nagel and Randall J. Cohrs and Donald H. Gilden and Bryan R. Cullen
Journal of Virology, ISSN 0022-538X, 10/2009, Volume 83, Issue 20, pp. 10677 - 10683
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MESSENGER-RNAS | TRANSCRIPTS | HERPES-SIMPLEX-VIRUS | CAENORHABDITIS-ELEGANS | VIROLOGY | STABLE INTRON | HUMAN-CELLS | GENE-EXPRESSION | HERPESVIRUSES | TYPE-1 | IDENTIFICATION | Virus Latency | Humans | Middle Aged | Alphaherpesvirinae - classification | Cercopithecus aethiops | Male | MicroRNAs - metabolism | Herpesvirus 1, Human - physiology | RNA, Viral - genetics | Herpesvirus 3, Human - metabolism | RNA, Viral - metabolism | Vero Cells | Alphaherpesvirinae - genetics | Herpesvirus 3, Human - physiology | Herpesvirus 1, Human - metabolism | Alphaherpesvirinae - metabolism | Herpesvirus 3, Human - genetics | Animals | RNA, Viral - chemistry | Gene Expression Regulation, Viral | Herpesvirus 1, Human - genetics | Aged | MicroRNAs - genetics | Alphaherpesvirinae - physiology | HeLa Cells | Trigeminal Ganglion - virology | MicroRNAs - chemistry | Virus-Cell Interactions
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9. Full Text Viral entry mechanisms: cellular and viral mediators of herpes simplex virus entry
by Akhtar, Jihan and Shukla, Deepak
The FEBS Journal, ISSN 1742-464X, 12/2009, Volume 276, Issue 24, pp. 7228 - 7236
Herpes simplex virus type‐1 and type‐2 are highly prevalent human pathogens causing life‐long infections. The process of infection begins when the virions bind... 
herpes simplex virus | entry | phagocytosis | endocytosis | glycoproteins | cell‐to‐cell spread | viral surfing | filopodia | herpes viruses | Endocytosis | Entry | Herpes viruses | Cell-to-cell spread | Glycoproteins | Viral surfing | Filopodia | Herpes simplex virus | Phagocytosis | HERPES-SIMPLEX-VIRUS-1 ENTRY | PILR-ALPHA | FUSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | cell-to-cell spread | RECEPTOR | NECTIN-1 | PIGMENT EPITHELIAL-CELLS | TYPE-1 ENTRY | SPREAD | GLYCOPROTEIN-B | 3-O-SULFATED HEPARAN-SULFATE | Viral Envelope Proteins - physiology | Herpesvirus 1, Human - physiology | Membrane Glycoproteins - physiology | Receptors, Immunologic - physiology | Pseudopodia - metabolism | Heparan Sulfate Proteoglycans - metabolism | Humans | Cell Communication - physiology | Herpesvirus 2, Human - physiology | Membrane Fusion - physiology | Virus Internalization | Herpes simplex | Cell research | Sulfates | Health aspects | Biochemistry | Cellular biology | Molecular biology | Binding sites
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10. Full Text Herpes simplex virus 1 ubiquitin-specific protease UL36 abrogates NF-κB activation in DNA sensing signal pathway
by Ye, Ruijie and Su, Chenhe and Xu, Haiyan and Zheng, Chunfu
Journal of Virology, ISSN 0022-538X, 2017, Volume 91, Issue 5
The DNA sensing pathway triggers innate immune responses against DNA virus infection, and NF-kappa B signaling plays a critical role in establishing innate... 
NF-κB | HSV-1 | DNA sensor | UL36 | IκBα | CYCLIC GMP-AMP | PHOSPHORYLATION | KINASE | BETA INTERFERON-PRODUCTION | ALPHA | REGULATORY FACTOR-3 | TEGUMENT PROTEIN | NF-kappa B | VIROLOGY | P65/RELA | I kappa B alpha | CYTOSOLIC-DNA | INNATE IMMUNITY | Herpesvirus 1, Human - physiology | Ubiquitination | Animals | Signal Transduction | Proteolysis | Humans | HEK293 Cells | Viral Proteins - physiology | Cercopithecus aethiops | NF-kappa B - metabolism | Interferon-beta - physiology | Vero Cells
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11. Full Text A comparison of herpes simplex virus type 1 and varicella-zoster virus latency and reactivation
by Kennedy, Peter G. E and Rovnak, Joel and Badani, Hussain and Cohrs, Randall J
Journal of General Virology, ISSN 0022-1317, 07/2015, Volume 96, Issue 7, pp. 1581 - 1602
Herpes simplex virus type 1 (HSV-1; human herpesvirus 1) and varicella-zoster virus (VZV; human herpesvirus 3) are human neurotropic alphaherpesviruses that... 
RNA-POLYMERASE-II | IN-VIVO REACTIVATION | VIROLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | EMBRYONIC STEM-CELLS | HUMAN-MELANOMA CELLS | IMMEDIATE-EARLY PROTEIN | COMPLETE DNA-SEQUENCE | HSV-1 GENE-EXPRESSION | DORSAL-ROOT GANGLIA | HUMAN TRIGEMINAL GANGLIA | PRIMARY SENSORY NEURONS | Neurons - virology | Herpesvirus 1, Human - physiology | Ganglia - virology | Gene Expression Regulation, Viral | Virus Latency | Epigenesis, Genetic | Humans | Transcription, Genetic | Virus Activation | Herpesvirus 3, Human - physiology | Review
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