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1. Full Text TLR3 Deficiency in Patients with Herpes Simplex Encephalitis
by Shen-Ying Zhang and Emmanuelle Jouanguy and Sophie Ugolini and Asma Smahi and Gaëlle Elain and Pedro Romero and David Segal and Vanessa Sancho-Shimizu and Lazaro Lorenzo and Anne Puel and Capucine Picard and Ariane Chapgier and Sabine Plancoulaine and Matthias Titeux and Céline Cognet and Horst von Bernuth and Cheng-Lung Ku and Armanda Casrouge and Xin-Xin Zhang and Luis Barreiro and Joshua Leonard and Claire Hamilton and Pierre Lebon and Bénédicte Héron and Louis Vallée and Lluis Quintana-Murci and Alain Hovnanian and Flore Rozenberd and Eric Vivier and Frédéric Geissmann and Marc Tardieu and Laurent Abel and Jean-Laurent Casanova
Science (American Association for the Advancement of Science), ISSN 0036-8075, 9/2007, Volume 317, Issue 5844, pp. 1522 - 1527
T lymphocytes | Double stranded RNA | Memory interference | Cell lines | Central nervous system | Fibroblasts | Human herpesvirus 1 | Viruses | Infections | Research Articles | Genetic mutation | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Biological and medical sciences | Infectious diseases | Medical sciences | Human viral diseases | Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye | Viral diseases | Interferons - biosynthesis | Encephalitis, Herpes Simplex - immunology | Dendritic Cells - immunology | Humans | Child, Preschool | Infant | Herpesvirus 1, Human - physiology | Genes, Dominant | Toll-Like Receptor 3 - deficiency | Leukocytes, Mononuclear - immunology | Killer Cells, Natural - immunology | Encephalitis, Herpes Simplex - genetics | Female | Toll-Like Receptor 3 - genetics | Fibroblasts - metabolism | Fibroblasts - virology | Cell Line | Poly I-C - pharmacology | Immunity, Innate | Keratinocytes - immunology | Toll-Like Receptor 3 - physiology | Alleles | Fibroblasts - immunology | Heterozygote | Toll-Like Receptor 3 - chemistry | Mutation | CD8-Positive T-Lymphocytes - immunology | Receptors | Research | Immunity | Health aspects | Herpes simplex encephalitis | Encephalitis | Immunology | Gene expression | Herpes viruses | Index Medicus | Encephalitis, Herpes Simplex | Toll-Like Receptor 3 | Killer Cells, Natural | Dendritic Cells | Interferons | Keratinocytes | Leukocytes, Mononuclear | Immunity, Natural | Herpesvirus 1, Human | CD8-Positive T-Lymphocytes | Life Sciences | Poly I-C
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2. Full Text S6K-STING interaction regulates cytosolic DNA-mediated activation of the transcription factor IRF3
by Wang, Fuan and Alain, Tommy and Szretter, Kristy J and Stephenson, Kyle and Pol, Jonathan G and Atherton, Matthew J and Hoang, Huy-Dung and Fonseca, Bruno D and Zakaria, Chadi and Chen, Lan and Rangwala, Zainab and Hesch, Adam and Chan, Eva Sin Yan and Tuinman, Carly and Suthar, Mehul S and Jiang, Zhaozhao and Ashkar, Ali A and Thomas, George and Kozma, Sara C and Gale, Michael and Fitzgerald, Katherine A and Diamond, Michael S and Mossman, Karen and Sonenberg, Nahum and Wan, Yonghong and Lichty, Brian D
Nature immunology, ISSN 1529-2908, 05/2016, Volume 17, Issue 5, pp. 514 - 522
Life Sciences & Biomedicine | Immunology | Science & Technology | Ovalbumin - immunology | Cytosol - immunology | Dendritic Cells - immunology | Humans | Immunoblotting | Interferon Regulatory Factor-3 - genetics | Herpesvirus 1, Human - physiology | Ribosomal Protein S6 Kinases, 90-kDa - metabolism | Bone Marrow Cells - immunology | HEK293 Cells | Adenoviridae - genetics | Herpesvirus 1, Human - immunology | Membrane Proteins - metabolism | Nucleotidyltransferases - metabolism | Adenoviridae - immunology | Dendritic Cells - metabolism | Protein-Serine-Threonine Kinases - metabolism | Interferon Regulatory Factor-3 - immunology | Ovalbumin - genetics | DNA - immunology | Immunization - methods | Membrane Proteins - genetics | Mice, Inbred C57BL | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Membrane Proteins - immunology | DNA - metabolism | Cytosol - virology | Ribosomal Protein S6 Kinases, 90-kDa - immunology | Herpes Simplex - immunology | Mice, Knockout | DNA - genetics | Herpes Simplex - virology | Animals | Ribosomal Protein S6 Kinases, 90-kDa - genetics | Interferon Regulatory Factor-3 - metabolism | Nucleotidyltransferases - genetics | Protein Binding | Cytosol - metabolism | Protein-Serine-Threonine Kinases - immunology | Nucleotidyltransferases - immunology | Bone Marrow Cells - metabolism | Transcription factors | Genetic aspects | Regulation | Immune response | Properties | Cellular control mechanisms | Index Medicus | Factors de transcripció | Gene expression | Expressió gènica
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3. Full Text Peptide-MHC class i tetramers can fail to detect relevant functional T cell clonotypes and underestimate antigen-reactive T cell populations
by Rius, Cristina and Attaf, Meriem and Tungatt, Katie and Bianchi, Valentina and Legut, Mateusz and Bovay, Amandine and Donia, Marco and Straten, Per Thor and Peakman, Mark and Svane, Inge Marie and Ott, Sascha and Connor, Tom and Szomolay, Barbara and Dolton, Garry and Sewell, Andrew K
The Journal of immunology (1950), ISSN 0022-1767, 04/2018, Volume 200, Issue 7, pp. 2263 - 2279
Life Sciences & Biomedicine | Immunology | Science & Technology | Staining and Labeling - methods | HLA-A2 Antigen - immunology | Humans | RNA-Binding Proteins - immunology | Herpesvirus 4, Human - immunology | Protein Binding - immunology | Orthomyxoviridae - immunology | Cytomegalovirus - immunology | Lymphocyte Activation - immunology | Melanoma - immunology | Receptors, Antigen, T-Cell - immunology | Tumor Cells, Cultured | CD8-Positive T-Lymphocytes - immunology | Lymphocytes, Tumor-Infiltrating - immunology | Protein Kinase Inhibitors - metabolism | Antigens | Populations | Enumeration | Staining | Autoantigens | Crosslinking | Lymphocytes T | Protein kinase inhibitors | Kinases | T-cell receptor | Cell activation | Major histocompatibility complex | Lymphocytes | Reagents | Phenotyping | Streptavidin | Affinity | Index Medicus | Abridged Index Medicus | Antigen Recognition and Responses
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4. Full Text Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells
by Lafaille, Fabien G and Pessach, Itai M and Zhang, Shen-Ying and Ciancanelli, Michael J and Herman, Melina and Abhyankar, Avinash and Ying, Shui-Wang and Keros, Sotirios and Goldstein, Peter A and Mostoslavsky, Gustavo and Ordovas-Montanes, Jose and Jouanguy, Emmanuelle and Plancoulaine, Sabine and Tu, Edmund and Elkabetz, Yechiel and Al-Muhsen, Saleh and Tardieu, Marc and Schlaeger, Thorsten M and Daley, George Q and Abel, Laurent and Casanova, Jean-Laurent and Studer, Lorenz and Notarangelo, Luigi D
Nature (London), ISSN 0028-0836, 11/2012, Volume 491, Issue 7426, pp. 769 - 773
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Biological and medical sciences | Infectious diseases | Medical sciences | Viral diseases | Neurons - pathology | Encephalitis, Herpes Simplex - immunology | Humans | Central Nervous System - pathology | Interferons - immunology | Central Nervous System - immunology | Membrane Transport Proteins - deficiency | Neural Stem Cells - immunology | Oligodendroglia - immunology | Astrocytes - immunology | Membrane Transport Proteins - genetics | Toll-Like Receptor 3 - deficiency | Herpesvirus 1, Human - immunology | Cell Differentiation | Toll-Like Receptor 3 - genetics | Induced Pluripotent Stem Cells - cytology | Child | Astrocytes - virology | Central Nervous System - virology | Neurons - virology | Disease Susceptibility | Cell Separation | Induced Pluripotent Stem Cells - virology | Neural Stem Cells - virology | Cells, Cultured | Neurons - immunology | Oligodendroglia - virology | Immunity, Innate | Encephalitis, Herpes Simplex - pathology | Oligodendroglia - pathology | Cell Lineage | Central Nervous System - cytology | Encephalitis, Herpes Simplex - virology | Encephalitis, Herpes Simplex - metabolism | Biomarkers | Herpesvirus 1, Human - pathogenicity | Neurons | Stem cells | Physiological aspects | Toll-like receptors | Virulence (Microbiology) | Research | Health aspects | Herpes simplex virus | Proteins | Epidermal growth factor | Patients | Index Medicus
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5. Full Text Cutting Edge: miR-223 and EBV miR-BART15 Regulate the NLRP3 Inflammasome and IL-1 beta Production
by Haneklaus, Moritz and Gerlic, Motti and Kurowska-Stolarska, Mariola and Rainey, Ashleigh-Ann and Pich, Dagmar and McInnes, Iain B and Hammerschmidt, Wolfgang and O'Neill, Luke A. J and Masters, Seth L
The Journal of immunology (1950), ISSN 0022-1767, 10/2012, Volume 189, Issue 8, pp. 3795 - 3799
Life Sciences & Biomedicine | Immunology | Science & Technology | Myeloid Cells - cytology | Protein Binding - genetics | Viral Matrix Proteins - genetics | Herpesvirus 4, Human - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | 3' Untranslated Regions - genetics | Monocytes - metabolism | Monocytes - immunology | Interleukin-1beta - genetics | Viral Matrix Proteins - physiology | Inflammasomes - biosynthesis | Cell Differentiation - genetics | Macrophages - virology | Inflammasomes - antagonists & inhibitors | Myeloid Cells - immunology | HEK293 Cells | Interleukin-1beta - biosynthesis | Cell Lineage - genetics | Macrophages - immunology | Interleukin-1beta - antagonists & inhibitors | Carrier Proteins - biosynthesis | Cells, Cultured | Herpesvirus 4, Human - immunology | Myeloid Cells - virology | Macrophages - cytology | Protein Binding - immunology | Inflammasomes - genetics | Carrier Proteins - genetics | Cell Differentiation - immunology | Monocytes - virology | Cell Line, Tumor | RNA, Viral - immunology | MicroRNAs - genetics | MicroRNAs - physiology | Cell Lineage - immunology | Index Medicus | Abridged Index Medicus
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6. Full Text Exhaustion of tumor-specific CD8+ T cells in metastases from melanoma patients
by Baitsch, Lukas and Baumgaertner, Petra and Devêvre, Estelle and Raghav, Sunil K and Legat, Amandine and Barba, Leticia and Wieckowski, Sébastien and Bouzourene, Hanifa and Deplancke, Bart and Romero, Pedro and Rufer, Nathalie and Speiser, Daniel E
The Journal of clinical investigation, ISSN 0021-9738, 06/2011, Volume 121, Issue 6, pp. 2350 - 2360
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | T-Lymphocyte Subsets - immunology | CD8-Positive T-Lymphocytes - pathology | Humans | Vaccination | Molecular Sequence Data | Cytomegalovirus Infections - immunology | Gene Expression Profiling | Cancer Vaccines - therapeutic use | Receptors, Immunologic - biosynthesis | CD8-Positive T-Lymphocytes - metabolism | MART-1 Antigen - immunology | CpG Islands - immunology | Epstein-Barr Virus Infections - immunology | Herpesvirus 4, Human - immunology | Melanoma - secondary | Cancer Vaccines - immunology | Cytomegalovirus - immunology | T-Lymphocyte Subsets - pathology | Melanoma - immunology | T-Lymphocyte Subsets - metabolism | T-Cell Antigen Receptor Specificity | CD8-Positive T-Lymphocytes - immunology | Melanoma - therapy | Receptors, Immunologic - genetics | Virus Latency - immunology | Lymphocytes, Tumor-Infiltrating - immunology | Index Medicus | Abridged Index Medicus | Life Sciences | Human health and pathology
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7. Full Text IFI16 is an innate immune sensor for intracellular DNA
by Baran, Marcin and Unterholzner, Leonie and Fitzgerald, Katherine A and Xiao, T Sam and Latz, Eicke and Paludan, Søren R and Bowie, Andrew G and Horan, Kristy A and Sharma, Shruti and Sirois, Cherilyn M and Jin, Tengchuan and Jensen, Søren B and Keating, Sinead E
Nature immunology, ISSN 1529-2908, 11/2010, Volume 11, Issue 11, pp. 997 - 1004
Life Sciences & Biomedicine | Immunology | Science & Technology | Phosphoproteins - immunology | Cell Line | Interferon-beta - immunology | Intracellular Space - immunology | Signal Transduction | Humans | Membrane Proteins - immunology | Monocytes - immunology | Immunity, Innate | Nuclear Proteins - immunology | DNA, Viral - immunology | Animals | Interferon-beta - metabolism | Herpesvirus 1, Human - immunology | Mice | DNA-Binding Proteins | Physiological aspects | Interferon | Immune response | DNA binding proteins | Biological response modifiers | Health aspects | Index Medicus
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8. Full Text TLR3 immunity to infection in mice and humans
by Zhang, Shen-Ying and Herman, Melina and Ciancanelli, Michael J and Pérez de Diego, Rebeca and Sancho-Shimizu, Vanessa and Abel, Laurent and Casanova, Jean-Laurent
Current opinion in immunology, ISSN 0952-7915, 2012, Volume 25, Issue 1, pp. 19 - 33
Allergy and Immunology | Life Sciences & Biomedicine | Immunology | Science & Technology | Genetic Predisposition to Disease | Virus Diseases - immunology | Humans | Immunity, Innate - genetics | Encephalitis - immunology | Toll-Like Receptor 3 - immunology | Signal Transduction - genetics | Adaptor Proteins, Vesicular Transport - immunology | Virus Diseases - complications | Mice, Knockout | Polymorphism, Genetic | Animals | RNA, Double-Stranded - immunology | Herpesvirus 1, Human - immunology | Mice | Toll-Like Receptor 3 - genetics | Encephalitis - etiology | Index Medicus
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