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1. Full Text Helminth infection reactivates latent γ-herpesvirus via cytokine competition at a viral promoter
by Reese, T.A and Wakeman, B.S and Choi, H.S and Hufford, M.M and Huang, S.C and Zhang, X and Buck, M.D and Jezewski, A and Kambal, A and Liu, C.Y and Goel, G and Murray, P.J and Xavier, R.J and Kaplan, M.H and Renne, R and Speck, S.H and Artyomov, M.N and Pearce, E.J and Virgin, H.W
Science, ISSN 0036-8075, 08/2014, Volume 345, Issue 6196, pp. 573 - 577
Mammals are coinfected by multiple pathogens that interact through unknown mechanisms. We found that helminth infection, characterized by the induction of the... 
B-CELLS | INTERFERON | VIRUS | TRANSACTIVATOR | MACROPHAGES | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | MURINE GAMMAHERPESVIRUS 68 | SWITCH GENE 50 | PROLIFERATION | ESTABLISHMENT | Virus Activation - physiology | Schistosomiasis mansoni - immunology | Humans | Nematospiroides dubius - immunology | Virus Latency - physiology | Interleukin-4 - pharmacology | Gammaherpesvirinae - genetics | Strongylida Infections - immunology | Ovum - immunology | Herpesvirus 8, Human - physiology | Macrophages - immunology | Promoter Regions, Genetic | Interleukin-4 - metabolism | Mice, Inbred C57BL | Herpesvirus 8, Human - genetics | Schistosoma mansoni - immunology | Virus Activation - genetics | STAT6 Transcription Factor - metabolism | Animals | Virus Activation - drug effects | Gene Expression Regulation, Viral | Interferon-gamma - immunology | Mice | Gammaherpesvirinae - physiology | Virus Replication - physiology | Interferon-gamma - pharmacology | Index Medicus | Immune systems | Pathogens | Viruses | Parasites | Worms | Flavours | Containment
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2. Full Text Construction and Manipulation of a New Kaposi's Sarcoma-Associated Herpesvirus Bacterial Artificial Chromosome Clone
by Kevin F. Brulois and Heesoon Chang and Amy Si-Ying Lee and Armin Ensser and Lai-Yee Wong and Zsolt Toth and Sun Hwa Lee and Hye-Ra Lee and Jinjong Myoung and Don Ganem and Tae-Kwang Oh and Jihyun F. Kim and Shou-Jiang Gao and Jae U. Jung
Journal of Virology, ISSN 0022-538X, 09/2012, Volume 86, Issue 18, pp. 9708 - 9720
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
VIROLOGY | LYTIC GENE-EXPRESSION | COMPLEX CLASS-I | ENDOTHELIAL-CELLS | ESCHERICHIA-COLI | DOWN-REGULATION | K5 PROTEINS | CLASS-I MOLECULES | T-CELLS | E3 UBIQUITIN LIGASE | IMMUNE EVASION | Humans | Cercopithecus aethiops | Molecular Sequence Data | Lymphoma, Primary Effusion - virology | Chromosomes, Artificial, Bacterial - genetics | Histocompatibility Antigens Class I - metabolism | Herpesvirus 8, Human - pathogenicity | Base Sequence | Gene Deletion | Cloning, Molecular | Plasmids - genetics | Viral Proteins - physiology | Vero Cells | Herpesvirus 8, Human - physiology | Genome, Viral | Immediate-Early Proteins - physiology | Viral Proteins - genetics | Herpesvirus 8, Human - genetics | Host-Pathogen Interactions | Animals | Immediate-Early Proteins - genetics | Escherichia coli - genetics | Gene Expression Regulation, Viral | Cell Line, Tumor | Mutation | DNA, Viral - genetics | Index Medicus | Genome and Regulation of Viral Gene Expression
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3. Full Text Kaposi's sarcoma-associated herpesvirus LANA recruits the DNA polymerase clamp loader to mediate efficient replication and virus persistence
by Qiming Sun and Toshiki Tsurimoto and Franceline Juillard and Lin Li and Shijun Li and Erika De León Vázquez and She Chen and Kenneth Kaye
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2014, Volume 111, Issue 32, pp. 11816 - 11821
Kaposi's sarcoma-associated herpesvirus (KSHV) latently infects tumor cells and persists as a multiple-copy, extrachromosomal, circular episome. To persist,... 
Nuclear antigens | Human herpesvirus 8 | DNA replication | Gels | Plasmids | DNA | Herpesviridae | Cell nucleus | Cell lines | Infections | CELLS | MITOTIC CHROMOSOMES | HOST CHROMOSOMES | NUCLEAR ANTIGEN | MULTIDISCIPLINARY SCIENCES | EPISOME PERSISTENCE | VIRAL GENOME | LATENCY | CHROMOSOME ASSOCIATION | BINDING | TERMINAL REPEATS | DNA, Viral - biosynthesis | Replication Protein C - antagonists & inhibitors | Humans | Herpesvirus 8, Human - genetics | Sarcoma, Kaposi - virology | Sarcoma, Kaposi - physiopathology | Virus Latency - physiology | Gene Knockdown Techniques | Host-Pathogen Interactions | Proliferating Cell Nuclear Antigen - physiology | DNA Replication - physiology | Herpesvirus 8, Human - pathogenicity | Antigens, Viral - physiology | Replication Protein C - genetics | Cell Line, Tumor | DNA-Directed DNA Polymerase - physiology | Nuclear Proteins - physiology | DNA, Viral - genetics | Replication Protein C - physiology | Virus Replication - physiology | Herpesvirus 8, Human - physiology | DNA polymerases | Host-parasite relationships | Research | Virus research | Health aspects | Antigens | DNA polymerase | Herpes viruses | Deoxyribonucleic acid--DNA | Cells | Tumors | Index Medicus | Biological Sciences
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4. Full Text Human herpesvirus 8 interferon regulatory factors 1 and 3 mediate replication and latency activities via interactions with USP7 deubiquitinase
by Xiang, Qiwang and Ju, Hyunwoo and Li, Qian and Mei, Szu-Chieh and Chen, Daming and Choi, Young Bong and Nicholas, John
Journal of Virology, ISSN 0022-538X, 04/2018, Volume 92, Issue 7
Human herpesvirus 8 (HHV-8) encodes four viral interferon regulatory factors (vIRF-1 to -4) that likely function to suppress innate immune and cellular stress... 
Human herpesvirus 8 | Lytic replication | USP7 | Viral interferon regulatory factors | Latency | UBIQUITIN-SPECIFIC PROTEASE | TRANSCRIPTIONAL ACTIVITY | BCL-2 HOMOLOG | lytic replication | NUCLEAR ANTIGEN | latency | SARCOMA-ASSOCIATED HERPESVIRUS | viral interferon regulatory factors | CELL-SURVIVAL | human herpesvirus 8 | INHIBITION | VIROLOGY | KAPOSIS-SARCOMA | MACAQUE RHADINOVIRUS INFECTION | P53 TUMOR-SUPPRESSOR | Gene Expression Regulation, Viral - physiology | Humans | Interferon Regulatory Factors - metabolism | Ubiquitin-Specific Peptidase 7 - genetics | Interferon Regulatory Factors - genetics | Viral Proteins - genetics | Ubiquitin-Specific Peptidase 7 - metabolism | Viral Proteins - metabolism | Virus Latency - physiology | Amino Acid Motifs | Herpesviridae Infections - pathology | HEK293 Cells | Cell Line, Tumor | Herpesviridae Infections - metabolism | Herpesviridae Infections - genetics | Herpesvirus 8, Human - physiology | Index Medicus
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5. Full Text Clinicopathologic analysis of TAFRO syndrome demonstrates a distinct subtype of HHV‐8‐negative multicentric Castleman disease
by Iwaki, Noriko and Fajgenbaum, David C and Nabel, Christopher S and Gion, Yuka and Kondo, Eisei and Kawano, Mitsuhiro and Masunari, Taro and Yoshida, Isao and Moro, Hiroshi and Nikkuni, Koji and Takai, Kazue and Matsue, Kosei and Kurosawa, Mitsutoshi and Hagihara, Masao and Saito, Akio and Okamoto, Masataka and Yokota, Kenji and Hiraiwa, Shinichiro and Nakamura, Naoya and Nakao, Shinji and Yoshino, Tadashi and Sato, Yasuharu
American Journal of Hematology, ISSN 0361-8609, 02/2016, Volume 91, Issue 2, pp. 220 - 226
Multicentric Castleman disease (MCD) describes a heterogeneous group of disorders involving systemic inflammation, characteristic lymph node histopathology,... 
BONE-MARROW FINDINGS | SYSTEMIC LYMPHOPROLIFERATIVE DISORDER | ANASARCA | KAPOSIS-SARCOMA | HIV | SARCOMA-ASSOCIATED HERPESVIRUS | THROMBOCYTOPENIA | LYMPH-NODE HYPERPLASIA | HEMATOLOGY | T-CELLS | MORPHOLOGIC FEATURES | Lymph Nodes - pathology | Thrombocytopenia - etiology | Humans | Middle Aged | Male | Thrombocytopenia - pathology | Syndrome | Plasma Cells - pathology | Young Adult | Castleman Disease - pathology | Platelet Count | Adult | Female | Aged | Herpesvirus 8, Human - physiology | Index Medicus
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6. Full Text The ephrin receptor tyrosine kinase A2 is a cellular receptor for Kaposi's sarcoma-associated herpesvirus
by Hahn, Alexander S and Kaufmann, Johanna K and Wies, Effi and Naschberger, Elisabeth and Panteleev-Ivlev, Julia and Schmidt, Katharina and Holzer, Angela and Schmidt, Martin and Chen, Jin and König, Simone and Ensser, Armin and Myoung, Jinjong and Brockmeyer, Norbert H and Stürzl, Michael and Fleckenstein, Bernhard and Neipel, Frank
Nature Medicine, ISSN 1078-8956, 06/2012, Volume 18, Issue 6, pp. 961 - 966
Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi's sarcoma(1), a highly vascularized tumor originating from lymphatic... 
ENTRY RECEPTOR | MEDICINE, RESEARCH & EXPERIMENTAL | DNA-SEQUENCES | TARGET-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | IN-VITRO | HUMAN-HERPESVIRUS-8 | EPITHELIAL-CELLS | GENE-EXPRESSION | SIMPLEX-VIRUS | HEPARAN-SULFATE | GLYCOPROTEIN-B | Cell Line | Viral Envelope Proteins - physiology | Endocytosis | Phosphorylation | Animals | Humans | Viral Proteins - physiology | Receptor, EphA2 - physiology | Mice | Herpesvirus 8, Human - physiology | Receptors, Virus - physiology | Cell receptors | Research | Herpesviruses | Identification and classification | Kaposi's sarcoma | Inhibitor drugs | Kinases | Herpes viruses | Kaposis sarcoma | Endothelium | Index Medicus
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7. Full Text Valganciclovir for Suppression of Human Herpesvirus-8 Replication: A Randomized, Double- Blind, Placebo-Controlled, Crossover Trial
by Casper, Corey and Krantz, Elizabeth M and Corey, Lawrence and Kuntz, Steven R and Wang, Jie and Selke, Stacy and Hamilton, Shannon and Huang, Meei-Li and Wald, Anna
The Journal of Infectious Diseases, ISSN 0022-1899, 7/2008, Volume 198, Issue 1, pp. 23 - 30
Background . Human herpesvirus-8 (HHV-8) replication is critical in the induction and maintenance of Kaposi sarcoma, primary effusion lymphoma, and some cases... 
REAL-TIME PCR | INFECTIOUS DISEASES | KAPOSIS-SARCOMA | SARCOMA-ASSOCIATED HERPESVIRUS | ACTIVE ANTIRETROVIRAL THERAPY | PRIMARY EFFUSION LYMPHOMA | MULTICENTRIC CASTLEMAN-DISEASE | INFECTED PATIENTS | PERIPHERAL-BLOOD | HUMAN-IMMUNODEFICIENCY-VIRUS | LYTIC REPLICATION | Herpesvirus 8, Human - drug effects | Virus Replication - drug effects | Double-Blind Method | Virus Shedding - drug effects | Antiviral Agents - therapeutic use | Ganciclovir - adverse effects | Humans | Middle Aged | Ganciclovir - analogs & derivatives | Male | Sarcoma, Kaposi - prevention & control | Cross-Over Studies | Oropharynx - virology | Antiviral Agents - adverse effects | HIV Infections - complications | Ganciclovir - therapeutic use | Adult | Aged | Patient Compliance | Herpesvirus 8, Human - physiology | Herpes | Care and treatment | Dosage and administration | Valganciclovir | Research | Herpesvirus diseases | Index Medicus | Abridged Index Medicus
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8. Full Text Modulation of mitochondrial antiviral signaling by human herpesvirus 8 interferon regulatory factor 1
by Hwang, Keun Young and Choi, Young Bong
Journal of Virology, ISSN 0022-538X, 2016, Volume 90, Issue 1, pp. 506 - 520
Mitochondrial lipid raft-like microdomains, experimentally also termed mitochondrial detergent-resistant membrane fractions (mDRM), play a role as platforms... 
APOPTOSIS | MAVS | PROTEIN | VIROLOGY | KAPOSIS-SARCOMA | MEMBRANE | LIPID RAFTS | HEPATITIS-C-VIRUS | RAFT-LIKE MICRODOMAINS | NF-KAPPA-B | INNATE IMMUNITY | Host-Pathogen Interactions | Cell Line | Immune Evasion | Signal Transduction | Humans | Interferon Regulatory Factors - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Viral Proteins - metabolism | Herpesvirus 8, Human - physiology | Herpesvirus 8, Human - immunology | Index Medicus
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9. Full Text miR-K12-7-5p encoded by Kaposi's sarcoma-associated herpesvirus stabilizes the latent state by targeting viral ORF50/RTA
by Lin, Xianzhi and Liang, Deguang and He, Zhiheng and Deng, Qiang and Robertson, Erle S and Lan, Ke
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 1, pp. e16224 - e16224
Seventeen miRNAs encoded by Kaposi's sarcoma-associated herpesvirus (KSHV) have been identified and their functions have begun to be characterized. Among these... 
REPLICATION | GENE | RNA | RBP-J-KAPPA | BIOLOGY | MICRORNAS | IDENTIFICATION | TRANSCRIPTIONAL REGULATION | EXPRESSION | RTA | LYTIC REACTIVATION | Cell Line | Immediate-Early Proteins - genetics | Virus Replication | Humans | Herpesvirus 8, Human - genetics | MicroRNAs - genetics | MicroRNAs - physiology | Trans-Activators - antagonists & inhibitors | RNA, Viral - physiology | Herpesvirus 8, Human - physiology | Immediate-Early Proteins - antagonists & inhibitors | Virus Latency - genetics | Sarcoma | Genes | MicroRNA | Antigens | Transcription | Laboratories | MiRNA | Viruses | Gene expression | Latency | Virology | Progeny | Immunology | Transfection | Kaposi's sarcoma | MicroRNAs | Herpes viruses | Lymphomas | Inhibition | Inducers | Apoptosis | Index Medicus | Immediate-Early Proteins | Life Sciences | Microbiology and Parasitology | Virus Latency | RNA, Viral | Trans-Activators | Herpesvirus 8, Human
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10. Full Text Epigenetic Regulation of Kaposi's Sarcoma-Associated Herpesvirus Latency by Virus-Encoded MicroRNAs That Target Rta and the Cellular Rbl2-DNMT Pathway
by Fang Lu and William Stedman and Malik Yousef and Rolf Renne and Paul M. Lieberman
Journal of Virology, ISSN 0022-538X, 03/2010, Volume 84, Issue 6, pp. 2697 - 2706
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
CONTROL REGION | METHYLATION | ACTIVATION | VIROLOGY | DNA METHYLTRANSFERASE-1 | SEQUENCES | NUCLEAR ANTIGEN | X PROTEIN | GENE-EXPRESSION | DOWN-REGULATION | INFECTION | Epigenesis, Genetic | Humans | Open Reading Frames | Molecular Sequence Data | MicroRNAs - metabolism | DNA (Cytosine-5-)-Methyltransferases - metabolism | Immediate-Early Proteins - metabolism | RNA, Viral - genetics | Herpesvirus 8, Human - metabolism | Retinoblastoma-Like Protein p130 - metabolism | Base Sequence | Gene Deletion | Trans-Activators - genetics | RNA, Viral - metabolism | Herpesvirus 8, Human - physiology | Genome, Viral | DNA (Cytosine-5-)-Methyltransferase 1 | Herpesvirus 8, Human - genetics | DNA (Cytosine-5-)-Methyltransferases - genetics | Sequence Alignment | Immediate-Early Proteins - genetics | Gene Expression Regulation, Viral | Signal Transduction - physiology | Trans-Activators - metabolism | MicroRNAs - genetics | Retinoblastoma-Like Protein p130 - genetics | Virus Latency - genetics | Index Medicus | Virus-Cell Interactions
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11. Full Text Herpesviruses shape tumour microenvironment through exosomal transfer of viral microRNAs
by Yogev, Ohad and Henderson, Stephen and Hayes, Matthew John and Marelli, Sara Sofia and Ofir-Birin, Yifat and Regev-Rudzki, Neta and Herrero, Javier and Enver, Tariq
PLoS Pathogens, ISSN 1553-7366, 08/2017, Volume 13, Issue 8, pp. e1006524 - e1006524
Metabolic changes within the cell and its niche affect cell fate and are involved in many diseases and disorders including cancer and viral infections.... 
MECHANISM | MICROBIOLOGY | INDUCTION | HYPOXIA | VIROLOGY | KAPOSIS-SARCOMA | GLUCOSE-METABOLISM | AEROBIC GLYCOLYSIS | INFECTION | PROTEINS | CANCER-CELL METABOLISM | COMMUNICATION | PARASITOLOGY | Cell Line | Microscopy, Electron, Transmission | Sarcoma, Kaposi - metabolism | Humans | Sarcoma, Kaposi - virology | Tumor Microenvironment - physiology | Herpesviridae Infections - virology | Blotting, Western | RNA, Viral - genetics | Herpesvirus 8, Human - pathogenicity | Polymerase Chain Reaction | Exome - physiology | Herpesviridae Infections - metabolism | Virulence - physiology | MicroRNAs - genetics | Herpesvirus 8, Human - physiology | Infection | Glucose metabolism | Care and treatment | MicroRNA | Kaposi's sarcoma | Herpesviruses | Research | Health aspects | Crosstalk | Viruses | Biochemistry | Genomes | Biology | Exosomes | Cell fate | Metabolites | Etiology | Informatics | Supervision | University colleges | Immune system | Medical research | Sarcoma | MiRNA | Latent infection | Metabolism | Latency | Physical fitness | MicroRNAs | Glycolysis | Hypoxia | Viral infections | Cancer | Fitness | Tumors | Index Medicus
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12. Full Text Discovery of a Viral NLR Homolog that Inhibits the Inflammasome
by Sean M. Gregory and Beckley K. Davis and John A. West and Debra J. Taxman and Shu-ichi Matsuzawa and John C. Reed and Jenny P. Y. Ting and Blossom Damania
Science, ISSN 0036-8075, 1/2011, Volume 331, Issue 6015, pp. 330 - 334
The NLR (nucleotide binding and oligomerization, leucine-rich repeat) family of proteins senses microbial infections and activates the inflammasome, a... 
Human herpesvirus 8 | Monocytes | Plasmids | Cell death | REPORTS | Cell lines | Small interfering RNA | Cellular immunity | Infections | Grants | Vero cells | DNA-SEQUENCES | HUMAN-HERPESVIRUS-8 | KAPOSIS-SARCOMA | GENE | MURAMYL DIPEPTIDE | MULTIDISCIPLINARY SCIENCES | DISEASE | INFECTION | PATTERN-RECOGNITION RECEPTORS | CASPASE-1 ACTIVATION | SARCOMA-ASSOCIATED-HERPESVIRUS | Adaptor Proteins, Signal Transducing - chemistry | Inflammasomes - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Virus Latency | Humans | Molecular Sequence Data | Caspase 1 - metabolism | Viral Proteins - metabolism | Herpesvirus 8, Human - immunology | Transfection | Inflammasomes - antagonists & inhibitors | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | Interleukin-1beta - metabolism | Apoptosis Regulatory Proteins - genetics | Protein Interaction Domains and Motifs | Virus Activation | Herpesvirus 8, Human - physiology | Amino Acid Sequence | Cell Line | Viral Proteins - chemistry | Apoptosis Regulatory Proteins - chemistry | Viral Proteins - genetics | Herpesvirus 8, Human - genetics | Immunity, Innate | Caspase Inhibitors | Apoptosis Regulatory Proteins - metabolism | Monocytes - virology | Carrier Proteins - metabolism | Immune Evasion | Nod2 Signaling Adaptor Protein - metabolism | Virus Replication | Adaptor Proteins, Signal Transducing - genetics | Apoptosis Regulatory Proteins - antagonists & inhibitors | Cell Line, Tumor | Protein Binding | Adaptor Proteins, Signal Transducing - metabolism | Apoptosis | Discovery and exploration | Virus diseases | NOD-like receptors | Genetic aspects | Herpesviruses | Chemical properties | Cellular biology | Herpes viruses | Viral infections | Immune system | Cancer | Human | Binding | Progeny | Microorganisms | Modulation | Blocking | Activation | Inhibition | Nucleotides | Index Medicus | NLRP3 | Inflammasome | NLRP1 | NOD2 | KSHV | Innate Immunity
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