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Microvascular Research, ISSN 0026-2862, 05/2013, Volume 87, pp. 65 - 74
The purpose of the study was to evaluate the effects of hesperetin (Hsp) on diabetes-induced retinal oxidative stress, neuroinflammation and apoptosis in rats.... 
INDUCED ACTIVATION | TUMOR-NECROSIS-FACTOR | OPTIC-NERVE | EXPERIMENTAL GALACTOSEMIA | RETINOPATHY | PERIPHERAL VASCULAR DISEASE | CENTRAL-NERVOUS-SYSTEM | INFLAMMATORY RESPONSE | MULLER CELLS | CELL-DEATH | BASEMENT-MEMBRANE | Immunohistochemistry | Retina - drug effects | Tumor Necrosis Factor-alpha - metabolism | Diabetic Retinopathy - drug therapy | Inflammation - pathology | Diabetes Mellitus, Experimental - drug therapy | Retina - metabolism | Rats, Wistar | Apoptosis - drug effects | Glutathione - metabolism | Streptozocin | Caspase 3 - metabolism | Body Weight - drug effects | Male | Retina - immunology | Diabetic Retinopathy - pathology | Glial Fibrillary Acidic Protein - metabolism | Inflammation - metabolism | Retina - ultrastructure | Time Factors | Inflammation - drug therapy | Interleukin-1beta - metabolism | Inflammation Mediators - metabolism | Female | Diabetes Mellitus, Experimental - chemically induced | Diabetes Mellitus, Experimental - metabolism | Superoxide Dismutase - metabolism | Microscopy, Electron, Transmission | Diabetic Retinopathy - immunology | Anti-Inflammatory Agents - pharmacology | Rats | Inflammation - immunology | Antioxidants - pharmacology | Diabetic Retinopathy - metabolism | Blood Glucose - drug effects | Catalase - metabolism | Diabetes Mellitus, Experimental - immunology | Animals | Aquaporin 4 - metabolism | Diabetes Mellitus, Experimental - pathology | Hesperidin - pharmacology | Oxidative Stress - drug effects | Blood Glucose - metabolism | Diabetic retinopathy | Oxidative stress | Enzymes | Aquaporins | Heat shock proteins | Superoxide | Intermediate filament proteins | Restaurants | Apoptosis
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 01/2017, Volume 439, Issue C, pp. 369 - 378
Excessive bone resorption by osteoclasts plays an important role in osteoporosis. Bone loss occurs in ovariectomised (OVX) mice in a similar manner to that in... 
Osteoporosis | Osteoclasts | Inhibition | Neohesperidin | SURVIVAL | SIGNALING PATHWAYS | ACTIVATION | ACID | CELL-DERIVED OSTEOCLASTS | CATHEPSIN K | ALPHA | CELL BIOLOGY | ENDOCRINOLOGY & METABOLISM | ESTROGEN | POSTMENOPAUSAL WOMEN | NF-KAPPA-B | Ovariectomy - adverse effects | Luciferases - metabolism | Apoptosis - drug effects | Calcium - metabolism | NF-kappa B - metabolism | RNA, Messenger - metabolism | Osteoporosis - etiology | Proteolysis - drug effects | RANK Ligand - pharmacology | Osteoporosis - metabolism | Bone Resorption - metabolism | Female | Real-Time Polymerase Chain Reaction | Genes, Reporter | Osteoclasts - pathology | Bone Marrow Cells - cytology | Mice, Inbred C57BL | NFATC Transcription Factors - metabolism | RNA, Messenger - genetics | Cells, Cultured | Bone Resorption - complications | Osteoclasts - metabolism | Blotting, Western | Macrophages - metabolism | Animals | Cathepsin K - metabolism | Osteoporosis - pathology | Cell Differentiation - drug effects | NF-KappaB Inhibitor alpha - metabolism | Osteoporosis - complications | Tartrate-Resistant Acid Phosphatase - metabolism | Bone Resorption - pathology | Hesperidin - chemistry | Hesperidin - pharmacology | Hesperidin - analogs & derivatives | Macrophages - drug effects | Tartrate-Resistant Acid Phosphatase - genetics | Osteoclasts - drug effects | Citrus fruits | Medical colleges | Phosphatases | Flavones | Bioflavonoids | Cathepsins | T cells | Citrus | Bone resorption | Flavonoids | Analysis | Health aspects | Yuan (China)
Journal Article
Tumor Biology, ISSN 1010-4283, 1/2016, Volume 37, Issue 1, pp. 227 - 237
Journal Article
The Journal of Nutritional Biochemistry, ISSN 0955-2863, 01/2017, Volume 39, pp. 156 - 168
Dietary fiber-derived short-chain fatty acids (SCFA) and phenolics produced by the gut microbiome have multiple effects on health. We have tested the... 
Short-chain fatty acids | Polyphenol | Phase II metabolism | Transporter | Gut metabolism | SULFOTRANSFERASES | HYDROXYCINNAMIC ACIDS | BIOCHEMISTRY & MOLECULAR BIOLOGY | HESPERETIN | NUTRITION & DIETETICS | UDP-GLUCURONOSYLTRANSFERASES | FERULIC ACID | GENE-EXPRESSION | BUTYRATE | HEALTH | PHASE-II METABOLISM | CACO-2 CELLS | Fatty Acids, Volatile - pharmacology | Propionates - pharmacology | Butyrates - pharmacology | Humans | Hesperidin - metabolism | Neoplasm Proteins - metabolism | ATP Binding Cassette Transporter, Sub-Family G, Member 2 - metabolism | Intestinal Mucosa - drug effects | Polyphenols - metabolism | Intestinal Mucosa - cytology | Glucuronosyltransferase - genetics | Monocarboxylic Acid Transporters - metabolism | Biological Transport | Muscle Proteins - metabolism | Neoplasm Proteins - genetics | Caco-2 Cells | Lactates - pharmacology | Coumaric Acids - metabolism | Intestinal Mucosa - microbiology | Symporters - metabolism | Muscle Proteins - genetics | ATP Binding Cassette Transporter, Sub-Family G, Member 2 - genetics | Gastrointestinal Microbiome - drug effects | Glucuronosyltransferase - metabolism | Symporters - genetics | Acetates - pharmacology | Monocarboxylic Acid Transporters - genetics | Lactates | Enzymes | Metabolites | Microbiota (Symbiotic organisms) | RNA | Analysis | Physiological aspects | Phenols | Esters | Sulfates | Fatty acids | Resveratrol | HT-3′-glu, Hesperetin-3′-O-glucuronide | DMCA, 3,4-dimethoxycinnamic acid | ABCG2, ATP-binding cassette sub-family G member 2 (BCRP) | FA, Ferulic acid | FA-sul, Ferulic acid-4-O-sulfate | HT-7-sul, Hesperetin-7-O-sulfate | HT, Hesperetin | HT-7-glu, Hesperetin-7-O-glucuronide | HT-3′-sul, Hesperetin-3′-O-sulfate | ABCC, ATP-binding cassette sub-family C | SULT, Sulfotransferase | DHFA, Dihydroferulic acid | FA-glu, Ferulic acid-4-O-glucuronide | SA, Salicylic acid | UGT, Uridine diphosphate-glucuronosyl transferase | SCFA, Short-chain fatty acids
Journal Article
Life Sciences, ISSN 0024-3205, 2007, Volume 80, Issue 20, pp. 1821 - 1831
Journal Article
Gastroenterology, ISSN 0016-5085, 2008, Volume 134, Issue 7, pp. 2004 - 2013
Background & Aims: Chemotherapy with an anticancer agent generally causes gastrointestinal tract disorders such as vomiting and anorexia, but the mechanism... 
Gastroenterology and Hepatology | SEROTONIN RECEPTOR | GHRELIN LEVELS | SYMPTOMS | MICE | EMESIS | GASTROENTEROLOGY & HEPATOLOGY | STOMACH | Receptor, Serotonin, 5-HT2B - metabolism | Receptor, Serotonin, 5-HT2C - metabolism | Body Weight - drug effects | Drugs, Chinese Herbal - pharmacology | Male | Stomach - metabolism | Drugs, Chinese Herbal - metabolism | Anorexia - physiopathology | Quinolines - pharmacology | Serotonin Receptor Agonists - pharmacology | Dose-Response Relationship, Drug | Serotonin 5-HT2 Receptor Antagonists | Chalcones - pharmacology | Dopamine Antagonists - metabolism | Receptors, Ghrelin - metabolism | Indoles - pharmacology | Stomach - innervation | Stomach - drug effects | Drugs, Chinese Herbal - therapeutic use | Flavones - pharmacology | Acylation | Disease Models, Animal | Antineoplastic Agents | Rats | Thiophenes - pharmacology | Anorexia - metabolism | Dopamine Antagonists - therapeutic use | Receptors, Ghrelin - drug effects | Piperazines - pharmacology | Rats, Sprague-Dawley | Vagotomy | Cisplatin | Ghrelin - metabolism | Eating - drug effects | Gastrointestinal Agents - pharmacology | Ghrelin - blood | Animals | Dopamine Antagonists - pharmacology | Aminopyridines - pharmacology | Serotonin - metabolism | Gastrointestinal Agents - therapeutic use | Anorexia - prevention & control | Hesperidin - pharmacology | Protein Binding | Anorexia - chemically induced | Oligopeptides - pharmacology | Gastrointestinal Agents - metabolism | Medicine, Botanic | Medicine, Herbal
Journal Article
Brain Research, ISSN 0006-8993, 2011, Volume 1420, pp. 93 - 105
Abstract Incidence of stroke is considered to be a major cause of death throughout the world. The middle cerebral artery occlusion (MCAO) for 2 h followed by... 
Neurology | Neurobehavior | Inflammation | Middle cerebral artery occlusion | Hesperidin | GFAP | OXIDATIVE STRESS | VITAMIN-E | OXYGEN RADICALS | INFLAMMATORY RESPONSES | TRANSIENT FOCAL ISCHEMIA | NEUROSCIENCES | CELL-DEATH | BRAIN MITOCHONDRIA | IN-VITRO | CEREBRAL-ARTERY OCCLUSION | RAT-BRAIN | Hesperidin - therapeutic use | Reactive Oxygen Species - metabolism | Glutathione - metabolism | Glutathione Reductase - metabolism | Motor Activity - drug effects | Male | Nitric Oxide Synthase Type II | Dose-Response Relationship, Drug | Glial Fibrillary Acidic Protein | Encephalitis - drug therapy | Infarction, Middle Cerebral Artery - complications | Encephalitis - metabolism | Anti-Inflammatory Agents - therapeutic use | Superoxide Dismutase - metabolism | Disease Models, Animal | Glutathione Peroxidase - metabolism | Cytokines - metabolism | Anti-Inflammatory Agents - pharmacology | Encephalitis - pathology | Rats | Thiobarbituric Acid Reactive Substances - metabolism | Mitochondria - metabolism | Psychomotor Performance - drug effects | Mitochondria - drug effects | Catalase - metabolism | Brain Infarction - etiology | Animals | Hesperidin - pharmacology | Muscle Strength - drug effects | Encephalitis - etiology | Stroke (Disease) | Antioxidants | Animal behavior | Analysis | Brain damage | Superoxide | Intermediate filament proteins
Journal Article
Journal Article
Journal Article
Biological Trace Element Research, ISSN 0163-4984, 12/2015, Volume 168, Issue 2, pp. 462 - 471
Journal Article
Applied Microbiology and Biotechnology, ISSN 0175-7598, 4/2016, Volume 100, Issue 7, pp. 3061 - 3070
Journal Article