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Journal Article
PLoS Biology, ISSN 1544-9173, 2004, Volume 2, Issue 5, pp. 587 - 599
The conserved histone variant H2A.Z functions in euchromatin to antagonize the spread of heterochromatin. The mechanism by which histone H2A is replaced by... 
CHROMATIN REMODELING ENZYMES | BUDDING YEAST | ACETYLATION | SANT DOMAIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOLOGY | GENE-EXPRESSION | GLOBAL ANALYSIS | IDENTIFICATION | SACCHAROMYCES-CEREVISIAE | MASS-SPECTROMETRY | DNA-REPLICATION | Fungal Proteins - chemistry | Oligonucleotides - chemistry | Euchromatin - chemistry | Oligonucleotide Array Sequence Analysis | Histones - chemistry | Nucleosomes - chemistry | Epigenesis, Genetic | Humans | Molecular Sequence Data | Heterochromatin - chemistry | DNA-Binding Proteins - metabolism | Saccharomyces cerevisiae - metabolism | Cell Nucleus - metabolism | Chromatin Immunoprecipitation | Genome, Fungal | Transcription, Genetic | Binding Sites | Chromatin - chemistry | Gene Expression Regulation, Fungal | Protein Structure, Tertiary | Peptides - chemistry | Cell Survival | Drosophila | Adenosine Triphosphatases - metabolism | Transcription Factors - metabolism | Animals | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Adenosine Triphosphatases - chemistry | Saccharomyces cerevisiae Proteins - physiology | Adenosine Triphosphate - chemistry | Adenosine Triphosphatases - physiology | Saccharomyces cerevisiae Proteins - chemistry | Index Medicus | Molecular Biology | Gene Therapy | Genomics | Structural Biology | Genetics | Saccharomyces | Cell Biology | Proteins | Enzymes | Chromatin | Yeast
Journal Article
Molecular Cell, ISSN 1097-2765, 01/2008, Volume 29, Issue 1, pp. 92 - 101
Transcriptional activators, several different coactivators, and general transcription factors are necessary to access specific loci in the dense chromatin... 
DNA | UBIQUITINATION | COMPLEX | ACTIVATION | UBP8 | CHROMATIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | UBIQUITYLATION | DEUBIQUITYLATION | MESSENGER-RNA EXPORT | SAGA | CELL BIOLOGY | Transcription Factors - chemistry | p300-CBP Transcription Factors - physiology | Histone Acetyltransferases - chemistry | Humans | Recombinant Fusion Proteins - physiology | Molecular Sequence Data | Trans-Activators - chemistry | Drosophila melanogaster - genetics | Promoter Regions, Genetic - genetics | Trans-Activators - physiology | Drosophila melanogaster - metabolism | Drosophila Proteins - physiology | Endopeptidases - chemistry | Conserved Sequence | Ubiquitination - physiology | p300-CBP Transcription Factors - chemistry | Amino Acid Sequence | Cell Line | Transcription Factors - physiology | Transcription Factors, General - chemistry | Animals, Genetically Modified | Gene Silencing | Thiolester Hydrolases - physiology | RNA Polymerase II - physiology | Drosophila Proteins - chemistry | Transcription Factors - genetics | Histone Acetyltransferases - physiology | Multiprotein Complexes - physiology | Protein Interaction Mapping | Sequence Homology, Amino Acid | Transcription Factors, General - physiology | Multiprotein Complexes - chemistry | Sequence Alignment | Animals | Endopeptidases - genetics | Heterochromatin - genetics | Receptors, Androgen - genetics | Drosophila Proteins - genetics | Thiolester Hydrolases - chemistry | Transcription, Genetic - genetics | Endopeptidases - physiology | Histones | Index Medicus | p300-CBP Transcription Factors | Histone Acetyltransferases | Multiprotein Complexes | Receptors, Androgen | Recombinant Fusion Proteins | Life Sciences | Ubiquitination | Heterochromatin | Transcription, Genetic | Promoter Regions (Genetics) | Drosophila Proteins | Transcription Factors, General | Trans-Activators | Biochemistry, Molecular Biology | Thiolester Hydrolases | Transcription Factors | RNA Polymerase II | Drosophila melanogaster | Endopeptidases
Journal Article
Molecular Cell, ISSN 1097-2765, 07/2012, Volume 47, Issue 2, pp. 203 - 214
Journal Article
Biochemical Journal, ISSN 0264-6021, 1760, Volume 459, Issue 3, pp. 505 - 512
The tandem PHD (plant homeodomain) fingers of the CHD4 (chromodomain helicase DNA-binding protein 4) ATPase are epigenetic readers that bind either unmodified... 
Chromodomain helicase DNA-binding protein 4 (CHD4) | Plant homeodomain (PHD) | Inhibitor | Calixarene | Histone | Methylation | COMPLEX | PROTEIN | DEACETYLASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | HP1 CHROMO DOMAIN | SELECTIVE RECOGNITION | METHYLATED LYSINE | chromodomain helicase DNA-binding protein 4 (CHD4) | plant homeodomain (PHD) | DISCOVERY | FLUORESCENT | inhibitor | methylation | HETEROCHROMATIN | histone | calixarene | Indicators and Reagents - chemical synthesis | Hypoxia-Inducible Factor-Proline Dioxygenases - chemistry | Autoantigens - metabolism | Homeodomain Proteins - metabolism | Humans | Mi-2 Nucleosome Remodeling and Deacetylase Complex - genetics | Mi-2 Nucleosome Remodeling and Deacetylase Complex - metabolism | Hypoxia-Inducible Factor-Proline Dioxygenases - antagonists & inhibitors | Autoantigens - genetics | Chromatin Assembly and Disassembly - drug effects | Protein Subunits - metabolism | Chromosomal Proteins, Non-Histone - antagonists & inhibitors | Mi-2 Nucleosome Remodeling and Deacetylase Complex - antagonists & inhibitors | Calixarenes - chemistry | Drug Design | HEK293 Cells | Indicators and Reagents - pharmacology | Epigenesis, Genetic - drug effects | Lysine - metabolism | Indicators and Reagents - chemistry | Histones - antagonists & inhibitors | Peptide Fragments - genetics | Protein Subunits - genetics | Recombinant Proteins - metabolism | Lysine - analogs & derivatives | Peptide Fragments - metabolism | Chromosomal Proteins, Non-Histone - metabolism | Protein Interaction Domains and Motifs - drug effects | Calixarenes - pharmacology | Hypoxia-Inducible Factor-Proline Dioxygenases - genetics | Models, Molecular | Recombinant Proteins - chemistry | Calixarenes - chemical synthesis | Autoantigens - chemistry | Homeodomain Proteins - chemistry | Homeodomain Proteins - genetics | Chromosomal Proteins, Non-Histone - genetics | Peptide Fragments - chemistry | Hypoxia-Inducible Factor-Proline Dioxygenases - metabolism | Peptide Fragments - antagonists & inhibitors | Homeodomain Proteins - antagonists & inhibitors | Mi-2 Nucleosome Remodeling and Deacetylase Complex - chemistry | Protein Processing, Post-Translational | Protein Subunits - antagonists & inhibitors | Protein Subunits - chemistry | Histones - metabolism | Chromosomal Proteins, Non-Histone - chemistry | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2006, Volume 103, Issue 11, pp. 4186 - 4191
Human centromeres are specialized chromatin domains containing the centromeric histone H3 variant CENP-A. CENP-A nucleosomes are interspersed with nucleosomes... 
Chromatin | Heterochromatin | DNA | Genes | Centromeres | Cell lines | Histones | Antibodies | Artificial chromosomes | Chromosomes | Centromere | Histone | CENP-A | α-satellite | centromere | DE-NOVO CENTROMERES | TOPOISOMERASE-II | KINETOCHORE | MULTIDISCIPLINARY SCIENCES | ACTIVE GENES | alpha-satellite | heterochromatin | ALPHA-SATELLITE DNA | HISTONE H3 | FUNCTIONAL HUMAN CENTROMERE | histone | HUMAN ARTIFICIAL CHROMOSOMES | EUCHROMATIN | Chromatin - metabolism | Autoantigens - metabolism | Immunoprecipitation | Humans | Centromere - metabolism | Heterochromatin - chemistry | Centromere - chemistry | Centromere Protein A | Heterochromatin - metabolism | Polymerase Chain Reaction | Transcription, Genetic | Chromosomes, Artificial, Human - genetics | Chromosomes, Artificial, Human - chemistry | Chromatin - chemistry | DNA, Satellite - chemistry | DNA, Satellite - metabolism | Cell Line | Chromosomal Proteins, Non-Histone - metabolism | Chromosomes, Human - genetics | In Situ Hybridization, Fluorescence | Autoantigens - chemistry | Chromosomes, Human - metabolism | DNA - metabolism | Chromosomes, Human - chemistry | DNA - genetics | DNA - chemistry | Centromere - genetics | Chromosomes, Artificial, Human - metabolism | DNA, Satellite - genetics | Chromosomal Proteins, Non-Histone - chemistry | Research | Genetics | Deoxyribonucleic acid | Index Medicus | Biological Sciences
Journal Article
EMBO reports, ISSN 1469-221X, 10/2018, Volume 19, Issue 10, pp. e44445 - n/a
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2011, Volume 286, Issue 27, pp. 24300 - 24311
Histone modifications and DNA methylation represent two layers of heritable epigenetic information that regulate eukaryotic chromatin structure and gene... 
RESIDUAL DIPOLAR COUPLINGS | 3-WAY DECOMPOSITION | DNA METHYLATION | STRUCTURAL BASIS | MULTIDOMAIN PROTEIN | LYSINE METHYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | EMBRYONIC STEM-CELLS | BINDING-PROTEIN | MAMMALIAN-CELLS | PERICENTROMERIC HETEROCHROMATIN | CCAAT-Enhancer-Binding Proteins - metabolism | Protein Structure, Tertiary | Histones - chemistry | Humans | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Gene Expression Regulation - physiology | Crystallography, X-Ray | CpG Islands - physiology | Heterochromatin - chemistry | Protein Processing, Post-Translational - physiology | Mice, Knockout | Animals | Cyclin-Dependent Kinase Inhibitor p16 - chemistry | Heterochromatin - genetics | Histones - genetics | Heterochromatin - metabolism | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Nuclear Magnetic Resonance, Biomolecular | CCAAT-Enhancer-Binding Proteins - chemistry | Mice | CCAAT-Enhancer-Binding Proteins - genetics | Histones - metabolism | DNA Methylation - physiology | Binding Sites | Index Medicus | Life Sciences | Cellular Biology | Biochemistry, Molecular Biology | METHYLATION | PROTEIN STRUCTURE | CHROMATIN | BASIC BIOLOGICAL SCIENCES | LYSINE | CRYSTALLOGRAPHY | HISTONES | MAINTENANCE | MODIFICATIONS | MUTANTS | PEPTIDES | DNA | GENES | HETEROCHROMATIN | GENERAL AND MISCELLANEOUS//MATHEMATICS, COMPUTING, AND INFORMATION SCIENCE | TARGETS | AROMATICS | REGULATIONS | PROTEINS | NMR | Histone PTMs | Molecular Biophysics | X-ray Crystallography | Gene Silencing | Epigenetics | Protein Structure | Tudor Domain
Journal Article