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Endocrinology, ISSN 0013-7227, 04/2017, Volume 158, Issue 4, pp. 903 - 919
...; inhibited renal Nrf2 and angiotensinogen (Agt) gene expression; and upregulated heterogeneous nuclear ribonucleoprotein F and K (hnRNP F and hnRNP K... 
CATALASE | OVEREXPRESSION | ELEMENT | ANGIOTENSINOGEN GENE | CONVERTING ENZYME-2 EXPRESSION | PREVENTS HYPERTENSION | BARDOXOLONE METHYL | KIDNEY INJURY | ENDOCRINOLOGY & METABOLISM | CELL-LINE | TUBULAR APOPTOSIS | Transcription, Genetic - drug effects | Gene Expression - drug effects | Diabetes Mellitus, Type 1 - metabolism | Diabetic Nephropathies - drug therapy | Male | Promoter Regions, Genetic - drug effects | Kidney - metabolism | NF-E2-Related Factor 2 - genetics | Insulin - pharmacology | Kidney - drug effects | Diabetic Nephropathies - metabolism | Diabetes Mellitus, Type 1 - genetics | Angiotensinogen - metabolism | Diabetic Nephropathies - genetics | Mice, Transgenic | Heterogeneous-Nuclear Ribonucleoprotein Group F-H - genetics | Heterogeneous-Nuclear Ribonucleoprotein K - genetics | Diabetes Mellitus, Type 1 - drug therapy | Heterogeneous-Nuclear Ribonucleoprotein Group F-H - metabolism | Angiotensinogen - genetics | Heterogeneous-Nuclear Ribonucleoprotein K - metabolism | Animals | Signal Transduction - drug effects | NF-E2-Related Factor 2 - metabolism | Mice | Insulin - therapeutic use | Mitogen-Activated Protein Kinases - metabolism | Oxidative stress | Transcription | Regulatory sequences | Kinases | Antioxidants | Hyperglycemia | Transfection | Rodents | AGT gene | Angiotensinogen | Inhibition | NRF2 protein | Deoxyribonucleic acid--DNA | Hypertension | Kidneys | K gene | Diabetes mellitus | MAP kinase | Gene expression | Insulin | Signaling | Injury prevention | Nephropathy | Protein kinase | Diabetes
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 31, pp. 12801 - 12812
.... Our analysis revealed that two protein spots typically present on 2D-PAGE gels and containing heterogeneous nuclear ribonucleoprotein K (hnRNP K... 
post-translational modification (PTM) | ACTIVATION | redox regulation | PROTEIN | proteomics | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | IDENTIFICATION | Heat shock factor protein 1 (HSF1) | HNRNP-K | heat shock protein (HSP) | DNA | ARGININE METHYLATION | hnRNP K | STRESS | BINDING | mass spectrometry (MS) | C-SRC | HSP70 Heat-Shock Proteins - antagonists & inhibitors | Humans | Gene Expression Profiling | RNA, Messenger - metabolism | Recombinant Fusion Proteins - metabolism | Heat Shock Transcription Factors | DNA-Binding Proteins - metabolism | HSP27 Heat-Shock Proteins - genetics | Heterogeneous-Nuclear Ribonucleoprotein K - antagonists & inhibitors | RNA Interference | HEK293 Cells | Ribonucleoproteins - genetics | HSP27 Heat-Shock Proteins - antagonists & inhibitors | DNA-Binding Proteins - antagonists & inhibitors | Hot Temperature - adverse effects | Oxidation-Reduction | Response Elements | Gene Expression Regulation | HSP70 Heat-Shock Proteins - genetics | Transcription Factors - antagonists & inhibitors | Ribonucleoproteins - metabolism | Recombinant Fusion Proteins - chemistry | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Heterogeneous-Nuclear Ribonucleoprotein K - genetics | HSP70 Heat-Shock Proteins - metabolism | Ribonucleoproteins - antagonists & inhibitors | Transcription Factors - metabolism | Heterogeneous-Nuclear Ribonucleoprotein K - metabolism | Animals | Cystine - metabolism | Cell Line, Tumor | HSP27 Heat-Shock Proteins - metabolism | Recombinant Fusion Proteins - genetics | Mice | Protein Processing, Post-Translational | Mutation | Amino Acid Substitution | Protein Synthesis and Degradation
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2407 - 12
Journal Article
Cell, ISSN 0092-8674, 2005, Volume 123, Issue 6, pp. 1065 - 1078
.... Through differential proteomics, we identify heterogeneous nuclear ribonucleoprotein K (hnRNP K) as being rapidly induced by DNA damage in a manner that requires the DNA-damage signaling kinases ATM or ATR... 
GEL-ELECTROPHORESIS | BOX-BINDING-PROTEIN | RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | GENE-EXPRESSION | SINGLE-STRANDED-DNA | CELL-CYCLE CHECKPOINTS | ATAXIA-TELANGIECTASIA | CANCER | NUCLEAR RIBONUCLEOPROTEIN-K | CELL BIOLOGY | Cell Cycle - genetics | RNA, Small Interfering - genetics | Proto-Oncogene Proteins c-mdm2 - genetics | Gene Expression - drug effects | Humans | Ribonucleoproteins - physiology | Ubiquitin - metabolism | Promoter Regions, Genetic - genetics | Pyrones - pharmacology | Tumor Suppressor Protein p53 - genetics | DNA-Binding Proteins - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Transfection | Ultraviolet Rays | DNA Damage - physiology | Tumor Suppressor Proteins - genetics | Cell Cycle Proteins - genetics | Ribonucleoproteins - genetics | Proto-Oncogene Proteins c-mdm2 - metabolism | Protein-Serine-Threonine Kinases - metabolism | Radiation, Ionizing | Cell Line | Tumor Suppressor Proteins - metabolism | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Tumor Suppressor Protein p53 - metabolism | Morpholines - pharmacology | Ribonucleoproteins - metabolism | Ataxia Telangiectasia Mutated Proteins | DNA-Binding Proteins - genetics | Gene Expression - radiation effects | Heterogeneous-Nuclear Ribonucleoprotein K - genetics | Heterogeneous-Nuclear Ribonucleoprotein K - physiology | Leupeptins - pharmacology | Heterogeneous-Nuclear Ribonucleoprotein K - metabolism | Animals | Phleomycins - pharmacology | Cysteine Proteinase Inhibitors - pharmacology | Cell Cycle - physiology | Cell Line, Tumor | Protein Binding | Protein Kinase Inhibitors - pharmacology | Proteasome Endopeptidase Complex - metabolism | Transcription, Genetic - genetics | Proteasome Inhibitors | RNA, Small Interfering - metabolism | DNA damage | Cell cycle | Genetic research | Genetic aspects | Research | Mammals | DNA repair | Ubiquitin | Ligases | Oncology, Experimental | DNA | Tumor proteins | Phosphotransferases | Cancer
Journal Article
Molecular Cell, ISSN 1097-2765, 10/2015, Volume 60, Issue 2, pp. 208 - 219
Eukaryotic cells possess numerous dynamic membrane-less organelles, RNP granules, enriched in RNA and RNA-binding proteins containing disordered regions. We... 
TRANSITION | EUKARYOTIC STRESS GRANULES | CELL-FREE FORMATION | PRION-LIKE DOMAINS | NUCLEOLI | BEHAVIOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | REGIONS | BODIES | P GRANULES | AGGREGATION | CELL BIOLOGY | Organelles - chemistry | Fluorescence Recovery After Photobleaching | Humans | Polyethylene Glycols - chemistry | Amyloid - chemistry | Cytoplasmic Granules - chemistry | Molecular Mimicry | Amyloid - metabolism | Protein Aggregation, Pathological - pathology | Solutions | Cytoplasmic Granules - metabolism | Escherichia coli - metabolism | Heterogeneous-Nuclear Ribonucleoprotein Group A-B - genetics | Protein Aggregation, Pathological - genetics | RNA - metabolism | Sodium Chloride - chemistry | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Amyloid - genetics | Gene Expression | Recombinant Proteins - chemistry | Heterogeneous-Nuclear Ribonucleoprotein Group A-B - metabolism | Recombinant Proteins - genetics | RNA - chemistry | Intrinsically Disordered Proteins - genetics | Heterogeneous Nuclear Ribonucleoprotein A1 | Heterogeneous-Nuclear Ribonucleoprotein Group A-B - chemistry | Escherichia coli - genetics | Intrinsically Disordered Proteins - chemistry | Protein Binding | Organelles - metabolism | Protein Aggregation, Pathological - metabolism | Intrinsically Disordered Proteins - metabolism | Fluorescence | Marine biology | Chemical properties | RNA | Binding proteins | Protein binding | Yuan (China)
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2012, Volume 7, Issue 8, p. e42106
...) and via the ADMA-RG-repeat to the NP9 protein of the human endogenous retrovirus K (HERV-K (HML-2) Type 1). The hypothesis of this work was that the methylated RG... 
RNA-POLYMERASE-II | SM PROTEINS | PROTEIN ARGININE METHYLTRANSFERASE | MESSENGER-RNA | MULTIDISCIPLINARY SCIENCES | C-MYC | GENE-EXPRESSION | DOWN-REGULATION | SPLICING FACTOR | MOTOR-NEURON PROTEIN | LIVING CELLS | Epstein-Barr Virus Nuclear Antigens - immunology | Viral Matrix Proteins - genetics | Herpesvirus 4, Human - genetics | Immunoprecipitation | Humans | Viral Proteins - immunology | Epstein-Barr Virus Nuclear Antigens - chemistry | Molecular Sequence Data | snRNP Core Proteins - metabolism | Promoter Regions, Genetic - genetics | Viral Proteins - metabolism | Arginine - analogs & derivatives | Multiprotein Complexes - metabolism | Repetitive Sequences, Amino Acid | Transfection | Antibody Specificity - immunology | Viral Matrix Proteins - metabolism | Epstein-Barr Virus Nuclear Antigens - metabolism | Antibodies, Monoclonal - immunology | Cell Line | Viral Proteins - chemistry | Herpesvirus 4, Human - physiology | Mutant Proteins - metabolism | DNA - metabolism | Protein Transport | Heterogeneous-Nuclear Ribonucleoprotein K - metabolism | Gene Expression Regulation, Viral | Protein Binding | Methylation | Epstein-Barr Virus Infections - metabolism | Arginine - metabolism | Cellular proteins | Arginine | Monoclonal antibodies | Epstein-Barr virus | Glycine | Antigenic determinants | Protein binding | Transformation | Intensive care | Transcription factors | Viruses | Homology | Biochemistry | Medical schools | Surface structure | Proteins | Conserved sequence | Immunology | E coli | Coding | Lymphocytes | DNA methylation | LMP2A protein | Deoxyribonucleic acid--DNA | Binding | Motor neurons | Antigens | Enzymes | Immunoglobulins | Cell survival | Environmental health | Gene expression | Membrane proteins | Virology | Ribonucleoprotein K | Lymphocytes B | Cellular structure | Deoxyribonucleic acid | DNA
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2011, Volume 6, Issue 11, p. e27045
...: We identified heterogeneous nuclear ribonucleoprotein K (hnRNPK), a 65 kDa ssDNA/RNA-binding-protein that is involved in multiple intracellular signaling cascades, as a binding partner of Abi-1 at postsynaptic sites... 
NERVOUS-SYSTEM | XENOPUS-LAEVIS | MESSENGER-RNA TRANSLATION | DOMAIN PROTEINS | STEM-CELLS | MULTIDISCIPLINARY SCIENCES | SYNAPSE FORMATION | CELL-PROLIFERATION | N-WASP | BINDING | HNRNP-K | NIH 3T3 Cells | RNA, Small Interfering - genetics | Immunoprecipitation | Actins - metabolism | Cercopithecus aethiops | Neurons - cytology | Immunoenzyme Techniques | Heterogeneous-Nuclear Ribonucleoprotein K - antagonists & inhibitors | Cell Nucleus - metabolism | In Situ Hybridization | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | Neurons - metabolism | Synapses - physiology | Cells, Cultured | Dendritic Spines - physiology | Rats | Hippocampus - cytology | Heterogeneous-Nuclear Ribonucleoprotein K - genetics | Blotting, Western | Hippocampus - metabolism | Two-Hybrid System Techniques | Heterogeneous-Nuclear Ribonucleoprotein K - metabolism | Phenotype | Animals | Pseudopodia - metabolism | Adaptor Proteins, Signal Transducing - genetics | Mice | Adaptor Proteins, Signal Transducing - metabolism | COS Cells | RNA | Muscle proteins | Actin | Neurons | Protein binding | Cerebellum | Brain | Neurosciences | Phosphorylation | Synaptogenesis | Spine | Central nervous system | Intracellular signalling | Nervous system | Biology | mRNA | Kinases | Proteins | Morphogenesis | Dendritic spines | Cell growth | Cascades | Binding | Neurochemistry | RNA-mediated interference | Granule cells | Polymerization | Pseudopodia | Gene expression | Ribonucleic acid--RNA | Ribonucleoprotein K | Morphology | Stem cells | Cytoskeleton | Ligands | Nuclei (cytology) | Postsynaptic density | Dendritic branching | Synapses | Hippocampus | Ribonucleic acid
Journal Article