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American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 09/2016, Volume 311, Issue 3, pp. H676 - H688
The cardiac pacemaker sets the heart's primary rate, with pacemaker discharge controlled by the autonomic nervous system through intra-cardiac ganglia. A... 
Intracardiac nervous system | Parasympathetic | Atrioventricular node | Sinoatrial node | Sympathetic | DANIO-RERIO | NERVOUS-SYSTEM | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | intracardiac nervous system | CONDUCTION SYSTEM | sympathetic | MUSCARINIC RECEPTORS | POSTGANGLIONIC NEURONS | sinoatrial node | ADULT ZEBRAFISH | ADRENERGIC-RECEPTORS | NUCLEUS AMBIGUUS | parasympathetic | VAGAL PREGANGLIONIC NEURONS | atrioventricular node | PERIPHERAL VASCULAR DISEASE | Muscarinic Agonists - pharmacology | Sympathetic Nervous System - drug effects | Heart - physiology | Sympathomimetics - pharmacology | Nicotinic Antagonists - pharmacology | Sinoatrial Node - drug effects | Atrioventricular Node - physiology | Atrioventricular Node - drug effects | Nicotine - pharmacology | Vagus Nerve Stimulation | Adrenergic beta-Antagonists - pharmacology | Hexamethonium - pharmacology | Sympathetic Nervous System - physiology | Muscarinic Antagonists - pharmacology | Electrocardiography | Models, Animal | Parasympathetic Nervous System - physiology | Nicotinic Agonists - pharmacology | Heart - innervation | Heart - physiopathology | Heart Rate | Receptor, Muscarinic M2 - metabolism | Autonomic Nervous System - drug effects | Isolated Heart Preparation | Sinoatrial Node - physiology | Autonomic Nervous System - physiology | Sinoatrial Node - physiopathology | Bradycardia - physiopathology | Atropine - pharmacology | Timolol - pharmacology | Zebrafish | Atrioventricular Node - innervation | Sinoatrial Node - innervation | Tachycardia - physiopathology | Receptors, Adrenergic, beta-2 - metabolism | Animals | Isoproterenol - pharmacology | Parasympathetic Nervous System - drug effects | Heart - drug effects | Muscarine - pharmacology | Atrioventricular Node - physiopathology | Health aspects | Pacemaker, Artificial (Heart) | Heart beat | Integrative Cardiovascular Physiology and Pathophysiology
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 2001, Volume 79, Issue 3, pp. 489 - 498
We have investigated mechanisms of nicotine-induced phosphorylation of extracellular signal-regulated protein kinase (p42/44 MAP kinase, ERK) and cAMP response... 
Nicotinic | Mitogen-activated protein kinase | Acetylcholine receptor | PC12 cells | cAMP response element binding protein | Nicotine | nicotine | nicotinic | C-FOS | TYROSINE-HYDROXYLASE | MAP KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALPHA-BUNGAROTOXIN | NEUROSCIENCES | NERVE GROWTH-FACTOR | mitogen-activated protein kinase | acetylcholine receptor | TRANSMITTER RELEASE | ACETYLCHOLINE-RECEPTORS | MESSENGER-RNA | SYNAPTIC TRANSMISSION | IMMEDIATE-EARLY GENES | MAP Kinase Signaling System - physiology | Phosphorylation | Calcium - metabolism | ras Proteins - metabolism | Neurons - cytology | Nicotinic Antagonists - pharmacology | PC12 Cells | Nicotine - pharmacology | Hexamethonium - pharmacology | Tubocurarine - pharmacology | Neurons - metabolism | Bungarotoxins - metabolism | Nicotinic Agonists - pharmacology | Insecticides - pharmacology | Nifedipine - pharmacology | Receptors, Nicotinic - metabolism | Enzyme Inhibitors - pharmacology | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Nerve Growth Factor - pharmacology | Rats | Aconitine - analogs & derivatives | Aconitine - pharmacology | Calcium Channel Blockers - pharmacology | Calcium-Calmodulin-Dependent Protein Kinases - antagonists & inhibitors | Potassium - pharmacology | Sulfonamides - pharmacology | Animals | MAP Kinase Signaling System - drug effects | Cyclic AMP Response Element-Binding Protein - metabolism | Benzylamines - pharmacology | Calmodulin - antagonists & inhibitors | Bungarotoxins - pharmacology | Mitogen-Activated Protein Kinases - metabolism
Journal Article
Journal Article
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 2007, Volume 294, Issue 1, pp. G165 - G173
The reflex response to distension of the small intestine in vivo is complex and not well understood. The aim of this study was to characterize the neural... 
Tachykinin receptors | Mouse | Nitric oxide | VPAC receptors | VIP | Intestinal mucosa | Chloride secretion | GUINEA-PIG ILEUM | nitric oxide | EXCITATORY SYNAPTIC INPUTS | SUBMUCOSAL NEURONS | PHYSIOLOGY | MOTOR-ACTIVITY | GASTROINTESTINAL-TRACT | intestinal mucosa | chloride secretion | mouse | DISTAL COLON | MYENTERIC NEURONS | tachykinin receptors | RECEPTORS MEDIATE | GASTROENTEROLOGY & HEPATOLOGY | CHOLERA-TOXIN | Duodenum - innervation | Lidocaine - pharmacology | Injections, Intravenous | Mechanotransduction, Cellular - drug effects | Colon - drug effects | Nitric Oxide Synthase - antagonists & inhibitors | Colon - innervation | Male | Ganglionic Blockers - pharmacology | Anesthetics, Local - pharmacology | Quinolines - pharmacology | Peripheral Nervous System Agents - administration & dosage | Receptors, Vasoactive Intestinal Peptide - metabolism | Hexamethonium - pharmacology | Piperidines - pharmacology | Time Factors | Vasoactive Intestinal Peptide - pharmacology | Muscarinic Antagonists - pharmacology | Chlorides - metabolism | Duodenum - metabolism | Receptors, Neurokinin-3 - metabolism | Receptors, Neurokinin-1 - metabolism | Tetrodotoxin - pharmacology | Granisetron - pharmacology | Neurokinin-1 Receptor Antagonists | Receptors, Neurokinin-3 - antagonists & inhibitors | Membrane Potentials - drug effects | Mice, Inbred C57BL | Quinuclidines - pharmacology | Enzyme Inhibitors - pharmacology | Rats | Atropine - pharmacology | Serotonin 5-HT3 Receptor Antagonists | Peripheral Nervous System Agents - pharmacology | Serotonin Antagonists - pharmacology | Pressure | Rats, Sprague-Dawley | Colon - metabolism | Hormone Antagonists - pharmacology | Nitroarginine - pharmacology | Animals | Intestinal Secretions - drug effects | Receptors, Serotonin, 5-HT3 - metabolism | Mice | Nitric Oxide Synthase - metabolism | Receptors, Vasoactive Intestinal Peptide - antagonists & inhibitors | Duodenum - drug effects | Vasoactive Intestinal Peptide | Duodenum | Gastroenterologi | pharmacology | Mechanotransduction | Muscarinic Antagonists | Gastroenterology and Hepatology
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 01/2006, Volume 290, Issue 1, pp. 357 - 364
Journal Article
Journal Article
Clinical and Experimental Pharmacology and Physiology, ISSN 0305-1870, 07/2007, Volume 34, Issue 7, pp. 574 - 580
SUMMARY • High-sodium intake may increase blood pressure and diabetes is a salt-sensitive condition. In the present study, we evaluated cardiovascular changes... 
diabetes mellitus | salt | streptozotocin | cardiovascular | hypertension | Hypertension | Salt | Cardiovascular | Streptozotocin | Diabetes mellitus | PHYSIOLOGY | AUTONOMIC DYSFUNCTION | ANGIOTENSIN-II | MELLITUS | RENAL HEMODYNAMICS | BLOOD-PRESSURE | DENERVATED RATS | CONSCIOUS RATS | DIETARY-SODIUM | ARTERIAL-PRESSURE | NITRIC-OXIDE | PHARMACOLOGY & PHARMACY | Vasopressins - antagonists & inhibitors | Body Weight | Kidney - pathology | Rats, Wistar | Sympathetic Nervous System - drug effects | Kidney - enzymology | Hematocrit | Male | Vasopressins - metabolism | Ganglionic Blockers - pharmacology | Nitroprusside - pharmacology | Sympathetic Nervous System - physiopathology | Angiotensin II Type 1 Receptor Blockers - pharmacology | Sympathetic Nervous System - metabolism | Diabetes Mellitus, Experimental - blood | Hypertension - blood | Heart Rate - drug effects | Hexamethonium - pharmacology | Phenylephrine - pharmacology | Peptidyl-Dipeptidase A - blood | Hypertension - chemically induced | Peptidyl-Dipeptidase A - metabolism | Blood Pressure - drug effects | Diabetes Mellitus, Experimental - metabolism | Hypertension - urine | Diabetes Mellitus, Experimental - physiopathology | Vasoconstrictor Agents - pharmacology | Vasodilator Agents - pharmacology | Losartan - pharmacology | Organ Size | Rats | Arginine Vasopressin - pharmacology | Renin - blood | Sodium Chloride, Dietary | Hypertension - physiopathology | Hormone Antagonists - pharmacology | Hypertension - metabolism | Baroreflex - drug effects | Arginine Vasopressin - analogs & derivatives | Animals | Diabetes Mellitus, Experimental - urine | Renin-Angiotensin System - drug effects | Blood Glucose - metabolism | Blood Pressure | Arginine Vasopressin, analogs and derivatives | Arginine Vasopressin, pharmacology | Hypertension, blood | Baroreflex, drug effects | Diabetes Mellitus, Experimental, urine | Sympathetic Nervous System, drug effects | Vasodilator Agents, pharmacology | Ganglionic Blockers, pharmacology | Hypertension, physiopathology | Hexamethonium, pharmacology | Hormone Antagonists, pharmacology | Renin-Angiotensin System | Sympathetic Nervous System, physiopathology | Blood Pressure, drug effects | Peptidyl-Dipeptidase A, blood | Vasoconstrictor Agents, pharmacology | Hypertension, metabolism | Peptidyl-Dipeptidase A, metabolism | Heart Rate | Renin, blood | Renin-Angiotensin System, drug effects | Diabetes Mellitus, Experimental, blood | Kidney, enzymology | Diabetes Mellitus, Experimental, physiopathology | Angiotensin II Type 1 Receptor Blockers, pharmacology | Heart Rate, drug effects | Sympathetic Nervous System, metabolism | Diabetes Mellitus, Experimental, metabolism | Nitroprusside, pharmacology | Vasopressins, antagonists and inhibitors | Vasopressins, metabolism | Blood Glucose, metabolism | Kidney, pathology | Phenylephrine, pharmacology | Baroreflex | Hypertension, chemically induced | Hypertension, urine | Losartan, pharmacology | Diabetes
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 11/2001, Volume 134, Issue 5, pp. 945 - 950
We have studied the effect of palmitoylethanolamide (PEA, 2.5 – 30 mg kg −1 , i.p.) on upper gastrointestinal transit in control mice and in mice with chronic... 
intestine | fatty acid amide hydrolase | palmitoylethanolamide | Intestinal motility | cannabinoid receptors | anandamide | inflammatory bowel disease | Inflammatory bowel disease | Intestine | Palmitoylethanolamide | Fatty acid amide hydrolase | Anandamide | Cannabinoid receptors | N-ACYLETHANOLAMINES | MACROPHAGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | INVOLVEMENT | PHENYLMETHYLSULFONYL FLUORIDE | CANNABINOID RECEPTOR | BIOSYNTHESIS | intestinal motility | PHARMACOLOGY & PHARMACY | Inflammation - chemically induced | Bornanes - pharmacology | Gastrointestinal Motility - drug effects | Nitric Oxide Synthase - antagonists & inhibitors | Male | Adrenergic alpha-Antagonists - pharmacology | Nicotinic Antagonists - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Yohimbine - pharmacology | Dose-Response Relationship, Drug | Hexamethonium - pharmacology | Piperidines - pharmacology | Phenylmethylsulfonyl Fluoride - pharmacology | Palmitic Acids - pharmacology | Endocannabinoids | Pyrazoles - pharmacology | NG-Nitroarginine Methyl Ester - pharmacology | Enzyme Inhibitors - pharmacology | Gastrointestinal Transit - drug effects | Ethanolamines | Intestine, Small - physiopathology | Mice, Inbred ICR | Croton Oil - administration & dosage | Animals | Naloxone - pharmacology | Intestine, Small - drug effects | Receptors, Cannabinoid | Mice | Intestine, Small - metabolism | Palmitic Acids - metabolism | Receptors, Drug - antagonists & inhibitors | Inflammation - physiopathology | Papers
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 12/2007, Volume 293, Issue 6, pp. 3246 - 3253
Acute intravenous Tempol reduces mean arterial pressure (MAP) and heart rate (HR) in spontaneously hypertensive rats. We investigated the hypothesis that the... 
Nitric oxide synthase | Superoxide dismutase | Adenosine 5′-triphosphate-activated potassium channels | Catalase | Sympathetic nervous system | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | POTASSIUM CHANNELS | sympathetic nervous system | SENSITIVE K+ CHANNELS | NITRIC-OXIDE SYNTHESIS | BLOOD-PRESSURE | adenosine 5 '-triphosphate-activated potassium channels | CALCIUM INFLUX | DOCA-SALT RATS | superoxide dismutase | ENDOTHELIAL-CELLS | SYMPATHETIC-NERVE ACTIVITY | PERIPHERAL VASCULAR DISEASE | HYDROGEN-PEROXIDE | nitric oxide synthase | catalase | Amitrole - pharmacology | Buthionine Sulfoximine - pharmacology | Antihypertensive Agents - pharmacology | Large-Conductance Calcium-Activated Potassium Channels - metabolism | Sympathetic Nervous System - drug effects | Catalase - antagonists & inhibitors | Glutathione Peroxidase - antagonists & inhibitors | Antihypertensive Agents - administration & dosage | Nitric Oxide Synthase - antagonists & inhibitors | Hypertension - drug therapy | Male | Large-Conductance Calcium-Activated Potassium Channels - antagonists & inhibitors | Cyclic N-Oxides - administration & dosage | Ganglionic Blockers - pharmacology | Spin Labels | Sympathetic Nervous System - physiopathology | Metalloporphyrins - pharmacology | Sympathetic Nervous System - metabolism | Dose-Response Relationship, Drug | Heart Rate - drug effects | Hexamethonium - pharmacology | KATP Channels - drug effects | Glyburide - pharmacology | Time Factors | Cyclic N-Oxides - pharmacology | Blood Pressure - drug effects | Heme Oxygenase (Decyclizing) - antagonists & inhibitors | Heme Oxygenase (Decyclizing) - metabolism | Potassium Channel Blockers - pharmacology | Disease Models, Animal | NG-Nitroarginine Methyl Ester - pharmacology | Rats, Inbred SHR | Glutathione Peroxidase - metabolism | Enzyme Inhibitors - pharmacology | Rats | Hypertension - physiopathology | Hypertension - metabolism | Peptides - pharmacology | Catalase - metabolism | KATP Channels - metabolism | Animals | Nitric Oxide Synthase - metabolism | Infusions, Intravenous | Cromakalim - pharmacology | Nitric Oxide - metabolism
Journal Article
Nature Neuroscience, ISSN 1097-6256, 10/2009, Volume 12, Issue 10, pp. 1293 - 1299
Journal Article
Cardiovascular Research, ISSN 0008-6363, 09/2010, Volume 87, Issue 4, pp. 760 - 768
The aim of the study is to investigate transient receptor potential ankyrin 1 (TRPA1)-induced responses in the vasculature and on blood pressure and heart rate... 
CGRP blood flow | Knockout mice | Blood pressure | TRP