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PLoS genetics, ISSN 1553-7404, 04/2019, Volume 15, Issue 4, pp. e1007739 - e1007739
Sleep disordered breathing (SDB)-related overnight hypoxemia is associated with cardiometabolic disease and other comorbidities. Understanding the genetic... 
INTERMITTENT HYPOXIA | OXYGEN DESATURATION | HEART-FAILURE | GENETICS & HEREDITY | OSTEOPOROTIC FRACTURES | COGNITIVE IMPAIRMENT | APNEA-HYPOPNEA | NLRP3 INFLAMMASOME | SEX-DIFFERENCES | PULMONARY-FIBROSIS | GENOME-WIDE ASSOCIATION | Humans | Middle Aged | Male | Gene Regulatory Networks | Genetic Variation | NLR Family, Pyrin Domain-Containing 3 Protein - genetics | Young Adult | Interleukin-18 Receptor alpha Subunit - genetics | Serine Endopeptidases - genetics | Aged, 80 and over | Adult | Female | Hexokinase - genetics | Genome-Wide Association Study | Oxyhemoglobins - metabolism | Extracellular Matrix Proteins - genetics | Computational Biology | Sleep Apnea Syndromes - blood | Sleep Apnea Syndromes - genetics | Sleep - genetics | Nerve Tissue Proteins - genetics | Cell Adhesion Molecules, Neuronal - genetics | Oxygen - blood | Hypoxia - blood | Hypoxia - genetics | Adolescent | Aged | Polymorphism, Single Nucleotide | Quantitative Trait Loci | Physiological aspects | Sleep disorders | Genetic aspects | Oxyhemoglobin | Interleukins | Genomics | Mortality | Genomes | Health aspects | Funding | Critical care | Single-nucleotide polymorphism | Epidemiology | Population genetics | Reelin protein | Consortia | Hypoxemia | Interleukin 1 | Bioinformatics | Public health | Phenotypes | Inflammation | Genetic diversity | Gene expression | Hexokinase | Interleukin 18 | Medicine | Nutrition research | Genetic variance | Sleep | Hospitals | Womens health | Replication | Respiration | Oxygenation | Index Medicus
Journal Article
BioMed Research International, ISSN 2314-6133, 2018, Volume 2018, pp. 8480762 - 15
The glycolytic enzyme Hexokinase (HKII) participates in tumor glycolysis and the progression of various cancers, but its clinicopathological effect on the... 
MEDICINE, RESEARCH & EXPERIMENTAL | INVASION | METASTASIS | METABOLISM | MECHANISM | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PROLIFERATION | WARBURG | TUMOR-GROWTH | CANCER | EXPRESSION | PROGRESSION | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Male | Epithelial-Mesenchymal Transition - genetics | Cell Movement - genetics | Glycolysis - genetics | Cell Differentiation - genetics | Squamous Cell Carcinoma of Head and Neck | Neoplasm Invasiveness - pathology | Lymphatic Metastasis - pathology | Female | Autophagy - genetics | Hexokinase - genetics | Gene Expression Regulation, Neoplastic - genetics | Tongue Neoplasms - genetics | Up-Regulation - genetics | Signal Transduction - genetics | Tongue Neoplasms - pathology | Down-Regulation - genetics | Head and Neck Neoplasms - pathology | Hypoxia - genetics | Lymphatic Metastasis - genetics | Cell Line, Tumor | Head and Neck Neoplasms - genetics | Neoplasm Invasiveness - genetics | Tongue | Deregulation | Mesenchyme | Metastasis | Glucose | Kinases | Tissues | Cancer therapies | Autophagy | Lymph nodes | Metastases | Proteins | Enzymes | Squamous cell carcinoma | Invasiveness | Metabolism | Gene expression | Hexokinase | Chemotherapy | Medical prognosis | Glycolysis | Hypoxia | Lactic acid | Cell migration | Phagocytosis | Apoptosis | Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 2015, Volume 6, Issue 1, pp. 6053 - 6053
Manganese superoxide dismutase (MnSOD/SOD2) is a mitochondria-resident enzyme that governs the types of reactive oxygen species egressing from the organelle to... 
HYPOXIA-INDUCIBLE FACTOR | LIFE-SPAN | OXIDATIVE STRESS | ACTIVATED PROTEIN-KINASE | EPITHELIAL-CELLS | MANGANESE SUPEROXIDE-DISMUTASE | MULTIDISCIPLINARY SCIENCES | INHIBIT APOPTOSIS | C-MYC | CELL-CYCLE PROGRESSION | BREAST | Mitochondria - enzymology | RNA, Small Interfering - genetics | AMP-Activated Protein Kinases - metabolism | Colonic Neoplasms - genetics | Superoxide Dismutase - genetics | Reactive Oxygen Species - metabolism | Humans | Transcriptional Activation | Gene Expression Regulation, Neoplastic | Phosphofructokinase-1 - genetics | Superoxide Dismutase - antagonists & inhibitors | Male | Glycolysis - genetics | Breast Neoplasms - enzymology | Prostatic Neoplasms - genetics | Mitochondria - genetics | Female | Hexokinase - genetics | Superoxide Dismutase - metabolism | Prostatic Neoplasms - pathology | Oxidation-Reduction | Pyruvate Kinase - metabolism | Signal Transduction | AMP-Activated Protein Kinases - antagonists & inhibitors | Hydrogen Peroxide - metabolism | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Colonic Neoplasms - pathology | Cell Line, Tumor | Prostatic Neoplasms - enzymology | Colonic Neoplasms - enzymology | Hexokinase - metabolism | Neoplasm Staging | Phosphofructokinase-1 - metabolism | Pyruvate Kinase - genetics | AMP-Activated Protein Kinases - genetics | RNA, Small Interfering - metabolism | Index Medicus
Journal Article
Metabolism, ISSN 0026-0495, 2005, Volume 54, Issue 8, pp. 1048 - 1055
In skeletal muscle of humans, transcription of several metabolic genes is transiently induced during recovery from exercise when no food is consumed. To... 
INSULIN | ACTIVATION | LIPID-METABOLISM | RAT | MESSENGER-RNA EXPRESSION | STIMULATED GLUCOSE-TRANSPORT | GLYCOGEN-CONTENT | KINASE | ENDOCRINOLOGY & METABOLISM | GLUT-4 PROTEIN EXPRESSION | SHORT-TERM | Carnitine O-Palmitoyltransferase - genetics | Protein Kinases - genetics | CD36 Antigens - genetics | Ion Channels | Physical Exertion - physiology | Humans | Male | Gene Expression Regulation, Enzymologic - physiology | Mitochondrial Proteins | RNA, Messenger - metabolism | Heat-Shock Proteins - genetics | Glycogen - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Adult | Energy Metabolism - genetics | Hexokinase - genetics | Monosaccharide Transport Proteins - genetics | Glycogen Synthase - genetics | Muscle, Skeletal - enzymology | Recovery of Function - genetics | Glucose Transporter Type 4 | Lipoprotein Lipase - genetics | PPAR alpha - genetics | Muscle, Skeletal - physiology | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Muscle Proteins - genetics | Carrier Proteins - genetics | Forkhead Box Protein O1 | Transcriptional Activation - physiology | Forkhead Transcription Factors | Uncoupling Protein 3 | Glycogen | Esterases | Lipoprotein lipase | Glucose | Blood lipoproteins | Fatty acids | Dextrose | Carnitine | Proteolipids | Lipoproteins | Exercise | Messenger RNA | Low carbohydrate foods | Nurses | Physiological aspects | Genetic research | Genetic aspects | Index Medicus
Journal Article
PLoS Genetics, ISSN 1553-7390, 2015, Volume 11, Issue 1, pp. e1004968 - e1004968
Journal Article
Oncology Reports, ISSN 1021-335X, 03/2017, Volume 38, Issue 3, pp. 1902 - 1908
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 1480 - 17
Glycolytic reprogramming is a typical feature of many cancers; however, key regulators of glucose metabolism reengineering are poorly understood, especially in... 
OXYGEN | LUNG-CANCER | APOPTOSIS | MIR-365 | HEXOKINASE 2 | PROTEIN | HYPOXIA-INDUCIBLE FACTOR-1-ALPHA | MULTIDISCIPLINARY SCIENCES | GROWTH | TRANSCRIPTION | GENE-EXPRESSION | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Homeodomain Proteins - metabolism | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Glucose Transporter Type 1 - metabolism | Male | MicroRNAs - metabolism | LIM Domain Proteins - metabolism | Case-Control Studies | Cellular Reprogramming | Glycolysis - genetics | Heterografts | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Female | Hexokinase - genetics | Protein-Serine-Threonine Kinases - metabolism | Skin Neoplasms - pathology | Promoter Regions, Genetic | Signal Transduction | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Protein-Serine-Threonine Kinases - genetics | Homeodomain Proteins - genetics | Skin Neoplasms - metabolism | Keratinocytes - pathology | Animals | Glucose Transporter Type 1 - genetics | Keratinocytes - metabolism | Mice, Nude | Skin Neoplasms - genetics | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Protein Binding | LIM Domain Proteins - genetics | Aged | MicroRNAs - genetics | Adaptor Proteins, Signal Transducing - metabolism | Hexokinase - metabolism | Repressing | Regulators | Squamous cell carcinoma | Target recognition | Reengineering | Gene expression | Metabolism | Homeobox | Glucose metabolism | Cell lines | Glycolysis | Tumor suppressor genes | Tumors | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, pp. e54115 - e54115
Journal Article