X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (97) 97
animals (81) 81
humans (69) 69
hedgehog proteins - metabolism (56) 56
signal transduction (48) 48
cell biology (41) 41
mice (39) 39
hh signaling (37) 37
expression (33) 33
hedgehog (32) 32
biochemistry & molecular biology (30) 30
sonic hedgehog (29) 29
developmental biology (26) 26
activation (25) 25
cancer (25) 25
sonic-hedgehog (24) 24
proteins (23) 23
growth (22) 22
hedgehog proteins - genetics (22) 22
oncology (22) 22
signal transduction - physiology (22) 22
article (20) 20
drosophila (20) 20
hedgehog protein (19) 19
stem cells (19) 19
analysis (18) 18
hedgehog gene (18) 18
male (18) 18
female (17) 17
gene expression (17) 17
pathway (17) 17
research (17) 17
zinc finger protein gli1 (17) 17
hedgehog proteins (16) 16
signal transduction - drug effects (16) 16
tumors (16) 16
cell line, tumor (15) 15
signal transduction - genetics (15) 15
apoptosis (14) 14
mutations (14) 14
pharmacology & pharmacy (14) 14
proliferation (14) 14
transcription factors - metabolism (14) 14
biology (13) 13
cell proliferation (13) 13
gene-expression (13) 13
hedgehog proteins - antagonists & inhibitors (13) 13
hh pathway (13) 13
mutation (13) 13
review (13) 13
gene (12) 12
hh, hedgehog (12) 12
immunohistochemistry (12) 12
stem-cells (12) 12
differentiation (11) 11
gene expression regulation, developmental (11) 11
genetic aspects (11) 11
hedgehog pathway (11) 11
hedgehog signaling pathway (11) 11
medicine (11) 11
signaling pathway (11) 11
transcription factors - genetics (11) 11
biophysics (10) 10
cells (10) 10
gli (10) 10
gli1 (10) 10
hh signaling pathway (10) 10
morphogenesis (10) 10
protein binding (10) 10
smoothened (10) 10
transcription (10) 10
tumorigenesis (10) 10
antineoplastic agents - pharmacology (9) 9
cell line (9) 9
genes (9) 9
hh (9) 9
inhibition (9) 9
medicine, research & experimental (9) 9
molecular biology (9) 9
transcription factors (9) 9
adult (8) 8
animal structures (8) 8
basal cell carcinoma (8) 8
chemotherapy (8) 8
genetics & heredity (8) 8
gli2 (8) 8
health aspects (8) 8
identification (8) 8
kinases (8) 8
life sciences (8) 8
medicine & public health (8) 8
mouse (8) 8
research article (8) 8
rna (8) 8
self-renewal (8) 8
shh (8) 8
wingless gene (8) 8
cell differentiation (7) 7
development (7) 7
endocrinology & metabolism (7) 7
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Bone, ISSN 8756-3282, 2016, Volume 109, pp. 43 - 48
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 4/2014, Volume 73, Issue 4, pp. 711 - 719
The pancreatic cancer has extremely low overall 5-year survival, and gemcitabine is the only approved single agent for pancreatic cancer treatment.In the... 
Medicine & Public Health | Gemcitabine | Perifosine | The pancreatic cancer | Oncology | Cancer Research | Hh–Gli signaling | Akt–mTOR | Pharmacology/Toxicology | Hh-Gli signaling | Akt-mTOR | APOPTOSIS | STEM-CELLS | AKT ACTIVATION | PROLIFERATION | HEDGEHOG | CHEMOTHERAPY | TRIAL | THERAPY | ONCOLOGY | PATHWAY | PHARMACOLOGY & PHARMACY | MTOR INHIBITORS | RNA, Small Interfering - genetics | Pancreatic Neoplasms - metabolism | Humans | Deoxycytidine - pharmacology | Male | Phosphorylcholine - analogs & derivatives | Phosphorylcholine - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Gene Knockdown Techniques | Dose-Response Relationship, Drug | Pancreatic Neoplasms - drug therapy | Phosphorylcholine - pharmacology | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Ribosomal Protein S6 Kinases, 70-kDa - antagonists & inhibitors | Deoxycytidine - administration & dosage | Pancreatic Neoplasms - pathology | Ribosomal Protein S6 Kinases, 70-kDa - genetics | Transcription Factors - antagonists & inhibitors | Random Allocation | Mice, SCID | Disease Progression | Drug Synergism | Transcription Factors - metabolism | Xenograft Model Antitumor Assays | Animals | Signal Transduction - drug effects | Survival Analysis | Cell Line, Tumor | Mice | Zinc Finger Protein GLI1 | RNA, Small Interfering - administration & dosage | Deoxycytidine - analogs & derivatives | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Antimitotic agents | Antineoplastic agents | Gliomas | Mitogens | Pancreatic cancer | Immunodeficiency
Journal Article
Cancer Research, ISSN 0008-5472, 04/2013, Volume 73, Issue 8, pp. 2650 - 2658
Journal Article
Autophagy, ISSN 1554-8627, 02/2015, Volume 11, Issue 2, pp. 355 - 372
The frontline tyrosine kinase inhibitor (TKI) imatinib has revolutionized the treatment of patients with chronic myeloid leukemia (CML). However, drug... 
apoptosis-related cysteine peptidase | hedgehog pathway | MAP1LC3B, microtubule-associated protein 1 light chain 3 β | ATG, autophagy-related | ACTB, actin | PARP, poly (ADP-ribose) polymerase | TKI, tyrosine kinase inhibitor | PBMC, human peripheral blood mononuclear cell | Hh, Hedgehog | AKT/protein kinase B, v-akt murine thymoma viral oncogene homolog | Bafi A1, bafilomycin A1 | CML, chronic myeloid leukemia | EIF4EBP1, eukaryotic translation initiation factor 4E binding protein 1 | MTOR, mechanistic target of rapamycin | autophagy | CML | BCR-ABL | CQ, chloroquine | siRNA, small interfering RNA | β | SQSTM1, sequestosome 1 | BCC, basal cell carcinoma | CASP, caspase | RPS6KB, ribosomal protein S6 kinase, 70kDa | HCQ, hydroxychloroquine | PCR, polymerase chain reaction | drug resistance | BCR-ABL, breakpoint cluster region-ABL proto-oncogene, non-receptor tyrosine kinase | CHRONIC MYELOGENOUS LEUKEMIA | ADVANCED SOLID TUMORS | STEM-CELL FUNCTION | SONIC HEDGEHOG | REGULATES AUTOPHAGY | KINASE INHIBITOR | CELL BIOLOGY | HYDROXYCHLOROQUINE | PROMOTES AUTOPHAGY | HEPATOCELLULAR-CARCINOMA | PHASE-I TRIAL | Leukocytes, Mononuclear - metabolism | Apoptosis - drug effects | Imatinib Mesylate - pharmacology | Humans | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Hedgehog Proteins - metabolism | Autophagy - drug effects | Signal Transduction - drug effects | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | K562 Cells | Cell Line, Tumor | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - metabolism | Antineoplastic Agents - pharmacology | Fusion Proteins, bcr-abl - metabolism | Drug Resistance, Neoplasm - drug effects
Journal Article
Developmental Biology, ISSN 0012-1606, 01/2020, Volume 457, Issue 1, pp. 1 - 8
Journal Article
Genes and Development, ISSN 0890-9369, 11/2014, Volume 28, Issue 22, pp. 2547 - 2563
Journal Article
Journal of Hematology and Oncology, ISSN 1756-8722, 2013, Volume 6, Issue 1, pp. 77 - 77
Background: Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) benefit Non-small cell lung cancer (NSCLC) patients, and an EGFR-TKIi... 
GDC-0449 | miRNAs | NSCLC | EMT | Hh signaling | Erlotinib resistance | ACTIVATION | ADENOCARCINOMA | LUNG-CANCER CELLS | CHEMOTHERAPY | TO-MESENCHYMAL TRANSITION | ONCOLOGY | GROWTH | RESISTANCE | HEMATOLOGY | CARCINOMA | ERLOTINIB | PROGRESSION | Erlotinib Hydrochloride | Lung Neoplasms - drug therapy | RNA, Small Interfering - genetics | Humans | Lung Neoplasms - metabolism | Hedgehog Proteins - metabolism | Drug Resistance, Neoplasm | Epithelial-Mesenchymal Transition - drug effects | Lung Neoplasms - pathology | Epithelial-Mesenchymal Transition - genetics | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Cisplatin - administration & dosage | Gene Knockdown Techniques | Transfection | Hedgehog Proteins - genetics | Quinazolines - administration & dosage | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Pyridines - administration & dosage | Signal Transduction | Carcinoma, Non-Small-Cell Lung - genetics | RNA, Small Interfering - pharmacology | Carcinoma, Non-Small-Cell Lung - metabolism | Cisplatin - pharmacology | Hedgehog Proteins - antagonists & inhibitors | Anilides - administration & dosage | Anilides - pharmacology | Cell Line, Tumor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | MicroRNAs - genetics | Pyridines - pharmacology | Carcinoma, Non-Small-Cell Lung - drug therapy | Quinazolines - pharmacology | Tyrosine | MicroRNA | Drug resistance | Lung cancer, Non-small cell | Hedgehog proteins | Studies | Medical research | Genotype & phenotype | Cell growth | Lung cancer | MicroRNAs | Cytotoxicity | Experiments
Journal Article
Journal Article