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Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 05/2019, Volume 119, Issue 5, pp. 834 - 843
Abstract The kallikrein/kinin system, an intravascular biochemical pathway that includes several proteins involved in the contact activation system of... 
Stroke, Systemic or Venous Thromboembolism | ACTIVATION | DESIGN | THROMBOSIS | ATHEROSCLEROSIS RISK | pulmonary embolus | FACTOR-XI | prospective study | INFLAMMATION | high molecular weight kininogen | COAGULATION | PERIPHERAL VASCULAR DISEASE | COHORT | MICE | prekallikrein | HEMATOLOGY | venous thrombosis
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2005, Volume 280, Issue 41, pp. 34832 - 34839
Antimicrobial peptides are important effectors of the innate immune system. These peptides belong to a multifunctional group of molecules that apart from their... 
VASCULAR-PERMEABILITY ENHANCEMENT | ACTIVATION | INHIBITS ANGIOGENESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOTHELIAL-CELLS | LIGHT-CHAIN | ANTIMICROBIAL PEPTIDE LL-37 | NEUTROPHIL ELASTASE | CYSTEINE PROTEINASE | BINDING | INNATE IMMUNITY | L-Lactate Dehydrogenase - metabolism | Glycosaminoglycans | Anti-Infective Agents - pharmacology | Humans | Neovascularization, Pathologic | Molecular Sequence Data | Kininogen, High-Molecular-Weight - chemistry | Time Factors | Pseudomonas aeruginosa - metabolism | Escherichia coli - metabolism | Cell Membrane - metabolism | Diffusion | Neutrophils - metabolism | Kininogens - chemistry | Hemolysis | Protein Structure, Tertiary | Amino Acid Sequence | Peptides - chemistry | Gram-Negative Bacteria | Antimicrobial Cationic Peptides - pharmacology | Models, Molecular | Tetrazolium Salts - pharmacology | Microscopy, Electron | Chemotaxis | Peptides - pharmacology | Sequence Homology, Amino Acid | Enterococcus faecalis - metabolism | Protein Conformation | Epitopes - chemistry | Thiazoles - pharmacology | Kinetics | Heparin - chemistry | Microscopy, Fluorescence | Apoptosis | Clinical Medicine | Other Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Dermatologi och venereologi | Dermatology and Venereal Diseases | Infektionsmedicin | Infectious Medicine | Annan klinisk medicin | Klinisk medicin
Journal Article
Thrombosis Research, ISSN 0049-3848, 2019, Volume 182, pp. 89 - 94
AbstractIntroductionHigh molecular weight kininogen (HK) and prekallikrein (PK) are proteins in the kallikrein/kinin system of the coagulation cascade. They... 
Hematology, Oncology, and Palliative Medicine | Heart failure | Cardiovascular disease | Ischemic stroke | Prekallikrein | Prospective study | High molecular weight kininogen
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 140, Issue 1, pp. 170 - 176
Background When the prekallikrein-high molecular weight kininogen complex is bound to endothelial cells, prekallikrein is stoichiometrically converted to... 
Allergy and Immunology | C1 inhibitor | bradykinin | Hereditary angioedema | heat shock protein 90 | HUMAN-PLASMA | CONTACT SYSTEM | COLLAGEN | PROTEIN | HUMAN FACTOR-XII | IMMUNOLOGY | HEPARIN | ALLERGY | CHRONIC URTICARIA | HAGEMAN-FACTOR | INHIBITOR | ORAL-CONTRACEPTIVES | Estrogens - pharmacology | Human Umbilical Vein Endothelial Cells - drug effects | Angioedemas, Hereditary - metabolism | Human Umbilical Vein Endothelial Cells - metabolism | Tissue Plasminogen Activator - metabolism | Humans | Cells, Cultured | Kininogen, High-Molecular-Weight - metabolism | Interleukin-1 - pharmacology | Tumor Necrosis Factor-alpha - pharmacology | Prekallikrein - metabolism | Urokinase-Type Plasminogen Activator - metabolism | Factor XII - metabolism | HSP90 Heat-Shock Proteins - metabolism | Estradiol - pharmacology | Cytokines | Bradykinin | Estrogen | Kallikrein | Heat shock proteins | Molecular biology | Endothelium | Enzymes | Angioneurotic edema | Phenols | Blood coagulation factors | Estradiol | Plasma | Cell culture | Hsp90 protein | Laboratories | Estrogens | Thrombin | Stimulation | Activation | Infections | Phosphatase | Plasmin | t-Plasminogen activator | Molecular weight | Proteins | Urokinase | Kininogen | Interleukin 1 | Kininogens | Enzyme-linked immunosorbent assay | Immunoglobulins | Statistical analysis | Secretion | Angioedema | Endothelial cells | U-Plasminogen activator | Complement component C1 | Coagulation factors | Sex hormones | Tumor necrosis factor | Collagen | Mutation | Heat shock
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 2015, Volume 113, Issue 3, pp. 603 - 613
Summary Cleaved high-molecular-weight kininogen (HKa) or its peptide domain 5 (D5) alone exert anti-adhesive properties in vitro related to impeding... 
Blood Cells, Inflammation and Infection | Cleaved high-molecular-weight kininogen (HKa) | Inflammation | Neointimal formation | Smooth muscle cells | Cell adhesion | PROGENITOR CELLS | LEUKOCYTE RECRUITMENT | neointimal formation | MECHANISMS | INTEGRIN MAC-1 | IDENTIFICATION | smooth muscle cells | inflammation | cell adhesion | RESTENOSIS | UROKINASE RECEPTOR | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | DIFFERENTIATION | HEMATOLOGY | EXPRESSION | Femoral Artery - pathology | Muscle, Smooth, Vascular - metabolism | Humans | Myocytes, Smooth Muscle - pathology | Male | Peptide Fragments - pharmacology | Green Fluorescent Proteins - genetics | Integrins - metabolism | Vascular System Injuries - pathology | Femoral Artery - injuries | Neointima | Chemotaxis, Leukocyte - drug effects | Time Factors | Kininogen, High-Molecular-Weight - pharmacology | U937 Cells | Bone Marrow Transplantation | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Peptide Fragments - genetics | Genes, Reporter | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Protein Structure, Tertiary | Peptide Fragments - metabolism | Mice, Inbred C57BL | Mice, Transgenic | Kininogen, High-Molecular-Weight - metabolism | Vascular System Injuries - prevention & control | Femoral Artery - drug effects | Vitronectin - metabolism | Kininogen, High-Molecular-Weight - genetics | Vascular System Injuries - metabolism | Muscle, Smooth, Vascular - injuries | Muscle, Smooth, Vascular - pathology | Animals | Green Fluorescent Proteins - biosynthesis | Femoral Artery - metabolism | Cell Proliferation - drug effects
Journal Article
Peptides, ISSN 0196-9781, 2011, Volume 32, Issue 12, pp. 2488 - 2496
Journal Article