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Advanced Science, ISSN 2198-3844, 12/2019, Volume 6, Issue 23, pp. 1901829 - n/a
Cancer immunotherapy based on the engineering of chimeric antigen receptors (CAR) on T cells has emerged as one of the most promising new therapies for... 
high‐content screening technology | CAR T cells | micropatterned cell array | cancer immunotherapy
Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 1223 - 9
Combining and multiplexing microscopy approaches is crucial to understand cellular events, but requires elaborate workflows. Here, we present a robust,... 
IMAGE | SUPERRESOLUTION MICROSCOPY | MULTIDISCIPLINARY SCIENCES | ARCHITECTURE | PAINT | BINDING | REVEALS | PROBES | Multiplexing | Freeware | Automation | Microscopy | Reproducibility | Automatic control | Labelling | Source code | Deoxyribonucleic acid--DNA | Fluidics | Life Sciences | Neurons and Cognition | Neurobiology
Journal Article
BMC BIOTECHNOLOGY, ISSN 1472-6750, 10/2019, Volume 19, Issue 1, pp. 1 - 10
Background Developmental biology relies to a large extent on the observation and comparison of phenotypic traits through time using high resolution... 
Automation | RECONSTRUCTION | Standardization | Zebrafish | 3D printed stamp | MICROSCOPY | GUIDE | Multidimensional imaging | Reproducibility | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | Quantitative imaging | CELL | High content imaging | Usage | Developmental biology | Zebra fish | Fluorescent proteins | Genetic aspects | Research | 3D printing
Journal Article
STEM CELLS Translational Medicine, ISSN 2157-6564, 11/2019, Volume 8, Issue 11, pp. 1180 - 1191
Journal Article
Journal of Applied Toxicology, ISSN 0260-437X, 11/2019, Volume 39, Issue 11, pp. 1532 - 1540
Journal Article
Micron, ISSN 0968-4328, 11/2019, Volume 126, p. 102718
The morphology of tumor cells is highly related to their phenotype and activity. To verify the drug response of a brain tumor patient, fluorescence microscope... 
High-content screening | Fluorescence microscope images | Brain tumor cell | Tile scan | Image stitching | MICROSCOPY
Journal Article
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, ISSN 1940-087X, 10/2019, Issue 152
C. elegans is the premier system for the systematic analysis of cell fate specification and morphogenetic events during embryonic development. One challenge is... 
image processing | C. elegans | development | embryogenesis | high-content imaging | embryonic development | MULTIDISCIPLINARY SCIENCES | embryo | Issue 152 | data visualization | Developmental Biology | semi-high-throughput
Journal Article
Methods and Protocols, ISSN 2409-9279, 10/2019, Volume 2, Issue 4, p. 83
Hypertrophic cardiomyopathy (HCM) is a prevalent and complex cardiovascular disease characterised by multifarious hallmarks, a heterogeneous set of clinical... 
cardiomyocytes | disease modelling | hypertrophy | drug screening | high-content imaging | high-throughput | hypertrophic cardiomyopathy | cellular models | phenotyping | mitochondrial respiration
Journal Article
Cell, ISSN 0092-8674, 10/2019, Volume 179, Issue 3, pp. 787 - 799.e17
Genetic screens are critical for the systematic identification of genes underlying cellular phenotypes. Pooling gene perturbations greatly improves scalability... 
pooled screen | CRISPR | optical pooled screen | in situ sequencing | functional genomics | high-content screening | CIRCUITS | ACTIVATION | SYSTEMATIC DISSECTION | WIDE SIRNA SCREEN | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENES | TRANSCRIPTION | NF-KAPPA-B | TNF | GENOME | FAMILY | CELL BIOLOGY | Research | Oncology, Experimental | Genomics | Cells | Cancer
Journal Article