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research article (11) 11
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hexahistidine tag (2) 2
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integral membrane protein folding (2) 2
mbp (2) 2
membrane-protein (2) 2
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protein structure, tertiary (2) 2
quaternary ammonium compounds (2) 2
quaternary cation compounds (2) 2
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small multidrug resistance protein (2) 2
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article (1) 1
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bc-peptide, amino acid residues 179gpevs... to ...ppqek277 of the calpastatin domain 1 fragment (1) 1
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Biochemical Journal, ISSN 0264-6021, 12/2007, Volume 408, Issue 3, pp. 297 - 315
The specificities of 65 compounds reported to be relatively specific inhibitors of protein kinases have been profiled against a panel of 70-80 protein kinases.... 
Drug discovery | Kinase profiling | Protein kinase | Anti-cancer drugs | Inhibitor specificity | RHO-ASSOCIATED KINASE | TUMOR PROGRESSION | FAMILY-MEMBERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-PROLIFERATION | protein kinase | P38 MAP KINASE | CYCLIN-DEPENDENT KINASES | RECEPTOR TYROSINE KINASES | drug discovery | kinase profiling | SB 203580 | anti-cancer drugs | ISOFORMS IN-VITRO | P90 RSK | inhibitor specificity | Amino Acid Sequence | Cell Line | Phosphorylation | Recombinant Proteins - antagonists & inhibitors | Animals | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Humans | Drug Design | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Mitogen-Activated Protein Kinases - metabolism | Spodoptera | Index Medicus | Yes1, Yamaguchi sarcoma viral oncogene homologue 1 | CSK, C-terminal Src kinase | Lck, lymphocyte cell-specific protein-tyrosine kinase | EGF, epidermal growth factor | FGF-R, fibroblast-growth-factor receptor | PAK, p21-activated protein kinase | PDK, 3-phosphoinositide-dependent protein kinase | PI3K, phosphatidylinositol (phosphoinositide) 3-kinase | NEK, NIMA (never in mitosis in Aspergillus nidulans)-related kinase | RSK, p90 ribosomal S6 kinase | HEK-293 cells, human embryonic kidney-293 cells | VEGF, vascular endothelial growth factor (vasoendothelial growth factor) | EF2K, elongation-factor-2 kinase | CK, casein kinase | PTEN, phosphatase and tensin homologue deleted on chromosome 10 | ERK, extracellular-signal-regulated kinase | ATM, ataxia telangiectasia mutated | SRPK, serine-arginine protein kinase | IL-1, interleukin 1 | MNK, MAPK-integrating protein kinase | ROCK, Rho-dependent protein kinase | CaMKK, CaMK kinase | GST, glutathione transferase | MKK1, MAPK kinase-1 (also called MEK1, MAPK or ERK kinase 1) | GAK, cyclin G-associated kinase | FMK, fluoromethylketone | MST, mammalian homologue Ste20-like kinase | PKA, cAMP-dependent protein kinase | FKBP, FK506-binding protein | PPAR, peroxisome-proliferator-activated receptor | IKK, inhibitory κB kinase | PH, pleckstrin homology | MBP, myelin basic protein | AICAR, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside | MAPKAP-K, MAPK-activated protein kinase | Sf21, Spodoptera frugiperda (fall armyworm) 21 | MARK, microtubule-affinity-regulating kinase | PIM, provirus integration site for Moloney murine leukaemia virus | LPS, lipopolysaccharide | MSK, mitogen- and stress-activated protein kinase | MAPK, mitogen-activated protein kinase | MELK, maternal embryonic leucine-zipper kinase | His6, hexahistidine | CAK, cyclin-dependent kinase-activating kinase | Eph-A2, Ephrin A2 receptor | PLK, polo-like kinase | ATF2, activating transcription factor 2 | PKD, protein kinase D | Src, sarcoma kinase | AMPK, AMP-activated protein kinase | MMS, methyl methanesulfonate | CHK, checkpoint kinase | JNK, c-Jun N-terminal kinase | TORC1, mTOR (mammalian target of rapamycin)–raptor (regulatory associated protein of mTOR) complex | BRSK, brain-specific kinase | RIP2, receptor-interacting protein 2 | IGF-1, insulin-like growth factor-1 | S6K1, S6 kinase 1 | DYRK, dual-specificity tyrosine-phosphorylated and -regulated kinase | HIPK, homeodomain-interacting protein kinase | ZMP, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside monophosphate | PRAK, p38-regulated activated kinase | PKC, protein kinase C | Src-I1, Src inhibitor 1 | TANK, TRAF (tumour-necrosis-factor-receptor-associated factor)-family-member-associated nuclear factor κB activator | NFAT, nuclear factor for activated T-cells | PHK, phosphorylase kinase | GSK3, glycogen synthase kinase 3 | PKB, protein kinase B (also called Akt) | CaMK, calmodulin-dependent kinase | CDK, cyclin-dependent protein kinase | NDRG, N-myc downstream-regulated gene | SmMLCK, smooth-muscle myosin light-chain kinase | TBK1, TANK-binding kinase 1 | PRK, protein kinase C-related kinase | SGK, serum- and glucocorticoid-induced kinase
Journal Article
Journal Article
Biochemistry and Biophysics Reports, ISSN 2405-5808, 05/2015, Volume 1, Issue 1, pp. 22 - 32
EmrE is a member of the small multidrug resistance (SMR) protein family in . EmrE confers resistance to a wide variety of quaternary cation compounds (QCCs) as... 
Hexahistidine (His6) tag | EmrE | Quaternary ammonium compounds (QAC) | Quaternary cation compounds (QCC) | Small multidrug resistance (SMR) protein | Integral membrane protein folding | Hexahistidine (His | tag
Journal Article
Biochemical Journal, ISSN 0264-6021, 07/2007, Volume 405, Issue 1, pp. 11 - 19
During apoptosis, the initiator caspase 9 is activated at the apoptosome after which it activates the executioner caspases 3 and 7 by proteolysis. During this... 
Caspase 3 | Feedback loop | Caspase 9 | Second mitochondrial activator of caspases (Smac) | X-linked inhibitor of apoptosis protein (XIAP) | Apoptosis | SMAC/DIABLO | ACTIVATION | second mitochondrial activator of caspases (Smac) | PROTEIN | MITOCHONDRIAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | apoptosis | DEATH | caspase 3 | CLEAVAGE | feedback loop | CYTOCHROME-C | caspase 9 | APAF-1 APOPTOSOME | BINDING | GRANZYME-B | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Amino Acid Sequence | Cell Line | Caspase 9 - genetics | Caspase 9 - metabolism | Humans | Caspase 3 - metabolism | Peptides - genetics | Cysteine Proteinase Inhibitors - metabolism | Molecular Sequence Data | Intracellular Signaling Peptides and Proteins - metabolism | Mitochondrial Proteins - genetics | Recombinant Proteins - genetics | Caspase Inhibitors | Thermodynamics | Peptides - metabolism | Mitochondrial Proteins - metabolism | X-Linked Inhibitor of Apoptosis Protein - metabolism | Amino Acid Chloromethyl Ketones - metabolism | Aspartic Acid - metabolism | Apoptosis - physiology | Enzyme Activation | Intracellular Signaling Peptides and Proteins - genetics | Index Medicus | CARD, caspase recruitment domain | ITC, isothermal titration calorimetry | MVPI, Met-Val-Pro-Ile | bEVD-aomk, biotinylhexanoyl-Asp-Glu-Val-acyloxymethane | Afc, 7-amido-4-fluoromethylcoumarin | DTT, dithiothreitol | IAP, inhibitor of apoptosis protein | HRP, horseradish peroxidase | Z-VAD-fmk, benzyloxycarbonyl-Val-Ala-Asp-fluoromethane | AVPI, Ala-Val-Pro-Ile | BIR, baculoviral inhibitory repeat | Smac, second mitochondrial activator of caspases | ICAD, inhibitor-of-caspase-activated DNAse | ABP, affinity-based probe | Apaf-1, apoptotic protease activating factor 1 | pNA, p-nitroanilide | cyt c, cytochrome c | XIAP, X-linked IAP | IBM, IAP-binding motif | His6, hexahistidine
Journal Article
Biochemical Journal, ISSN 0264-6021, 09/2005, Volume 390, Issue 2, pp. 513 - 520
NDH (NADH-quinone oxidoreductase)-1 complexes in cyanobacteria have specific functions in respiration and cyclic electron flow as well as in active CO, uptake.... 
Thylakoid membrane | NDH-1 complex | uptake | NAD(P)H dehydrogenase | Affinity purification | Cyanobacteria | RESPIRATORY-CHAIN | UBIQUINONE OXIDOREDUCTASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | MEMBRANE-PROTEIN | affinity purification | SYNECHOCYSTIS SP PCC-6803 | PROTON-TRANSLOCATING NADH | 3-DIMENSIONAL STRUCTURE | thylakoid membrane | THERMOPHILIC CYANOBACTERIUM | cyanobacteria | INORGANIC CARBON TRANSPORT | CO2 uptake | CYCLIC ELECTRON FLOW | Cyanobacteria - genetics | Amino Acid Sequence | Genes, Bacterial - genetics | Cyanobacteria - metabolism | Molecular Sequence Data | Cyanobacteria - enzymology | Electron Transport Complex I - metabolism | Protein Subunits - metabolism | Thylakoids - metabolism | Sequence Homology, Amino Acid | Multiprotein Complexes - metabolism | Electron Transport Complex I - chemistry | Electron Transport Complex I - isolation & purification | Multiprotein Complexes - chemistry | Sequence Alignment | Chromatography, Affinity | Cyanobacteria - cytology | Protein Subunits - isolation & purification | Protein Subunits - chemistry | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Nickel - metabolism | Index Medicus | WT, wild-type | PSI, Photosystem I | Cm, chloramphenicol | MS, electrospray ionization tandem MS | MALDI-TOF, matrix-assisted laser-desorption–ionization time-of-flight | BN, blue-native | β-DM, n-dodecyl β-D-maltoside | His-tag, histidine tag | ESI MS | Synechocystis 6803, Synechocystis sp. PCC 6803 | T. elongatus, Thermosynechococcus elongatus BP-1 | His6, hexahistidine
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 01/2006, Volume 393, Issue 1, pp. 107 - 115
The LOX-1 (lectin-like oxidized low-density lipoprotein receptor-1) scavenger receptor regulates vascular responses to oxidized-low-density-lipoprotein... 
Protein-lipid overlay | Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) | Liposomes | Recombinant protein | Phosphatidylserine | PHAGOCYTOSIS | ARTERY ENDOTHELIAL-CELLS | LIGAND-BINDING | liposomes | recombinant protein | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | LOW-DENSITY-LIPOPROTEIN | BINDING DOMAIN | protein-lipid overlay | phosphatidylserine | lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) | OXIDIZED LDL RECEPTOR-1 | Ca2 | SMOOTH-MUSCLE-CELLS | HUMAN LECTIN-LIKE | EXPRESSION | Cell Line | Scavenger Receptors, Class E - metabolism | Animals | Calcium - pharmacology | Calcium - metabolism | Humans | Phosphatidylserines - metabolism | Gene Expression Regulation | Protein Binding | Apoptosis | Index Medicus | hLOX-1, human LOX-1 | bv-LOX-1, baculovirus | TBS, Tris-buffered saline | IL-1β, interleukin-1β | HRP, horseradish peroxidase | PNGase F, N-glycosidase F | ec-LOX-1, bacterially expressed LOX-1 | PI, phosphatidylinositol | PC, phosphatidylcholine | GST, glutathione S-transferase | TNF-α, tumour necrosis factor-α | PE, phosphatidylethanolamine | PS, phosphatidylserine | ApoB-100, apolipoprotein B-100 | sTGN46, soluble His6-tagged trans-Golgi-network protein 46 | insect cell-expressed lectin-like oxidized low-density lipoprotein receptor-1 | Ni-NTA, Ni2+-nitrilotriacetate | MOI, multiplicity of infection | NK, natural killer | IPTG, isopropyl β-D-thiogalactoside | OxLDL, oxidized low-density lipoprotein | His6, hexahistidine
Journal Article
Biochemical Journal, ISSN 0264-6021, 08/2007, Volume 405, Issue 3, pp. 481 - 488
The ETS transcription factor Ets-1 (E26 transformation-specific-1) plays a critical role in many physiological processes including angiogenesis, haematopoietic... 
Small ubiquitin-like modifier (SUMO) | E26 transformation-specific-1 (Ets-1) | Ubiquitin (Ub) | Protein inhibitor of activated STAT (protein inhibitor of activated STAT) Y (PIASy) | ANDROGEN RECEPTOR | CELLS | DOMAIN | ACTIVATION | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | C-MYB | protein inhibitor of activated STAT (protein inhibitor of activated STAT) Y (PIASy) | SUMOYLATION | FAMILY | BREAST-CANCER | small ubiquitin-like modifier (SUMO) | ubiquitin (Ub) | TRANSCRIPTION FACTOR | Proto-Oncogene Protein c-ets-1 - metabolism | Humans | Gene Expression Regulation | Cercopithecus aethiops | Protein Inhibitors of Activated STAT - metabolism | Poly-ADP-Ribose Binding Proteins | Animals | Osteosarcoma | Protein Inhibitors of Activated STAT - genetics | Cell Line, Tumor | Proteasome Endopeptidase Complex - metabolism | COS Cells | Ubiquitins - metabolism | Index Medicus | RNAi, RNA interference | WT, wild-type | Ets-1, E26 transformation-specific-1 | CHX, cycloheximide | (E)GFP, (enhanced) green fluorescent protein | NLS, nuclear localization signal | RT, reverse transcription | siRNA, small interfering RNA | Sox9, sex-determining-region-Y-related high-mobility-group box 9 | TAD, transcriptional activation domain | NIH, National Insttiutes of Health | Ni-NTA, Ni2+ -nitrilotriacetate | IκBα, inhibitory κBα (also called inhibitor of nuclear factor κBα) | AR, androgen receptor | His6, hexahistidine | PIAS, protein inhibitor of activated STAT (signal transducer and activator of transcription) | SUMO, small ubiquitin-like modifier
Journal Article
Biochemistry and Biophysics Reports, ISSN 2405-5808, 03/2018, Volume 13, pp. 129 - 140
EmrE is a member of the small multidrug resistance (SMR) protein family in . It confers resistance to a wide variety of quaternary cation compounds (QCCs) as... 
Ligand binding | Hexahistidine (His6) tag | Structural plasticity | Quaternary cation compounds (QCC) | Dynamic light scattering | Integral membrane protein folding | EmrE | Quaternary ammonium compounds (QAC) | Small multidrug resistance (SMR) protein | Hexahistidine (His | tag
Journal Article
Biochemical Journal, ISSN 0264-6021, 08/2004, Volume 382, Issue 1, pp. 223 - 230
Journal Article
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