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Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 06/2013, Volume 169, Issue 3, pp. 632 - 644
Background and Purpose Pitolisant, a histamine H3 receptor inverse agonist/antagonist is currently under Phase III clinical trials for treatment of excessive... 
H3 receptor | monkeys | histamine | drug abuse | self‐administration | conditioned place preference | discrimination | sensitization | Pitolisant | rodents | receptor | self-administration | H-3 RECEPTOR | DOPAMINE RELEASE | RHESUS-MONKEYS | ARRIVE GUIDELINES | NUCLEUS-ACCUMBENS | DISCRIMINATIVE-STIMULUS | PHARMACOLOGY & PHARMACY | ANTAGONIST THIOPERAMIDE | LOCOMOTOR SENSITIZATION | PHARMACOLOGICAL-PROPERTIES | Dopamine - chemistry | Receptors, Histamine H3 - chemistry | Drugs, Investigational - adverse effects | Nucleus Accumbens - metabolism | Drugs, Investigational - therapeutic use | Motor Activity - drug effects | Male | Macaca mulatta | Histamine Antagonists - therapeutic use | Histamine Agonists - administration & dosage | Histamine Antagonists - adverse effects | Behavior, Addictive - prevention & control | Dose-Response Relationship, Drug | Benzhydryl Compounds - adverse effects | Central Nervous System Stimulants - adverse effects | Dopaminergic Neurons - metabolism | Dopaminergic Neurons - drug effects | Behavior, Animal - drug effects | Histamine Agonists - adverse effects | Drug Evaluation, Preclinical | Receptors, Histamine H3 - metabolism | Dopamine - metabolism | Histamine Agonists - therapeutic use | Wakefulness-Promoting Agents - administration & dosage | Wakefulness-Promoting Agents - therapeutic use | Piperidines - administration & dosage | Histamine Antagonists - administration & dosage | Rats | Animals | Behavior, Addictive - chemically induced | Drug Antagonism | Modafinil | Piperidines - therapeutic use | Drug Inverse Agonism | Piperidines - adverse effects | Drugs, Investigational - administration & dosage | Mice | Wakefulness-Promoting Agents - adverse effects | Nucleus Accumbens - drug effects | Histamine | Drug abuse | Cocaine | Narcolepsy | Comparative analysis | Dopamine | Rodents | Research Papers
Journal Article
Psychopharmacology, ISSN 0033-3158, 4/2013, Volume 226, Issue 3, pp. 615 - 622
Combination treatment with reboxetine, a selective norepinephrine reuptake inhibitor, and betahistine, a histamine H1 receptor agonist/H3 antagonist, was... 
Antipsychotics | Reboxetine | Body mass index | Neurosciences | Biomedicine | Olanzapine | Pharmacology/Toxicology | Psychiatry | Betahistine | Weight gain | DEPRESSION | PSYCHIATRY | HISTAMINE H-1 | FOOD-INTAKE | BEHAVIOR | RATS | NEUROSCIENCES | PHARMACOLOGY & PHARMACY | RATING-SCALE | RECEPTORS | APPETITE | Antipsychotic Agents - adverse effects | Humans | Middle Aged | Betahistine - administration & dosage | Male | Histamine Agonists - administration & dosage | Young Adult | Antipsychotic Agents - therapeutic use | Adult | Female | Histamine Agonists - adverse effects | Weight Gain - drug effects | Histamine Agonists - therapeutic use | Morpholines - adverse effects | Morpholines - therapeutic use | Adrenergic Uptake Inhibitors - adverse effects | Adrenergic Uptake Inhibitors - therapeutic use | Double-Blind Method | Morpholines - administration & dosage | Betahistine - adverse effects | Treatment Outcome | Antipsychotic Agents - administration & dosage | Betahistine - therapeutic use | Adrenergic Uptake Inhibitors - administration & dosage | Benzodiazepines - administration & dosage | Benzodiazepines - adverse effects | Schizophrenia - drug therapy | Benzodiazepines - therapeutic use | Antipsychotic drugs | Schizophrenia | Dosage and administration | Research | Drug therapy | Appetite | olanzapine | Neuroleptics | Statistical analysis | Mental disorders | Body weight | Central nervous system | Clinical trials | Histamine H1 receptors | Norepinephrine | reboxetine
Journal Article
Journal of Psychopharmacology, ISSN 0269-8811, 9/2012, Volume 26, Issue 9, pp. 1271 - 1279
Olanzapine is effective at treating multiple domains of schizophrenia symptoms. However, it induces serious metabolic side effects. Antipsychotic drug’s... 
olanzapine | Antipsychotic | locomotor activity | betahistine | weight gain | food intake | PSYCHIATRY | FOOD-INTAKE | BEHAVIOR | SCHIZOPHRENIA | NEUROSCIENCES | ANTIPSYCHOTIC-DRUG TREATMENT | CLINICAL NEUROLOGY | BODY-WEIGHT | 2ND-GENERATION ANTIPSYCHOTICS | FEMALE RATS | PHARMACOLOGY & PHARMACY | ANIMAL-MODEL | PLACEBO-CONTROLLED TRIAL | RECEPTORS | Histamine H3 Antagonists - adverse effects | Appetite Depressants - adverse effects | Antipsychotic Agents - adverse effects | Motor Activity - drug effects | Hyperphagia - chemically induced | Appetite Depressants - therapeutic use | Drug Interactions | Exploratory Behavior - drug effects | Behavior, Animal - drug effects | Female | Histamine Agonists - adverse effects | Weight Gain - drug effects | Histamine H3 Antagonists - therapeutic use | Receptors, Histamine H1 - chemistry | Histamine Agonists - therapeutic use | Disease Models, Animal | Betahistine - adverse effects | Rats | Random Allocation | Rats, Sprague-Dawley | Feeding Behavior - drug effects | Animals | Hyperphagia - prevention & control | Betahistine - therapeutic use | Benzodiazepines - adverse effects | Complications and side effects | Care and treatment | Olanzapine | Analysis | Rattus | Physiological aspects | Weight gain | Obesity | Neuroleptics | Mental disorders | Clinical trials | Schizophrenia | Body weight gain | Feeding | Histamine H3 receptors | Histamine | Side effects | Food intake | Histamine H1 receptors | Locomotor activity
Journal Article
Journal Article
Thorax, ISSN 0040-6376, 09/2009, Volume 64, Issue 9, pp. 763 - 769
Journal Article
Addiction, ISSN 0965-2140, 02/2012, Volume 107, Issue 2, pp. 361 - 369
Journal Article