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Blood, ISSN 0006-4971, 07/2017, Volume 130, Issue 2, pp. 167 - 175
Langerhans cell histiocytosis (LCH) and Erdheim-Chester disease (ECD) are rare histiocytic disorders induced by somatic mutation of MAPK pathway genes.... 
MANAGEMENT | DENDRITIC CELLS | NEOPLASMS | DISTINCT | MONOCYTES | SUBSETS | NOTCH | MUTATIONS | MATURATION | HEMATOLOGY | BLOOD | Antigens, CD - immunology | Dendritic Cells - immunology | Histiocytosis, Langerhans-Cell - diagnosis | Histiocytosis, Langerhans-Cell - genetics | Humans | Lectins, C-Type - immunology | Dendritic Cells - pathology | Hematopoietic Stem Cells - pathology | Erdheim-Chester Disease - immunology | Male | Receptors, Notch - genetics | Monocytes - immunology | Lectins, C-Type - genetics | Antigens, CD - genetics | Hematopoietic Stem Cells - immunology | Histiocytosis, Langerhans-Cell - pathology | Bone Marrow Cells - immunology | Monocytes - pathology | Adult | Female | Cell Differentiation | Foam Cells - pathology | Glycoproteins - genetics | Transforming Growth Factor beta - immunology | Antigens, CD1 - immunology | Diagnosis, Differential | Erdheim-Chester Disease - genetics | Gene Expression | Bone Marrow Cells - pathology | Immunophenotyping | Lipopolysaccharide Receptors - immunology | Histiocytosis, Langerhans-Cell - immunology | Erdheim-Chester Disease - pathology | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Glycoproteins - immunology | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Mannose-Binding Lectins - genetics | Mannose-Binding Lectins - immunology | Transforming Growth Factor beta - genetics | Proto-Oncogene Proteins B-raf - genetics | Proto-Oncogene Proteins B-raf - immunology | Alleles | Erdheim-Chester Disease - diagnosis | Lipopolysaccharide Receptors - genetics | Foam Cells - immunology | Antigens, CD1 - genetics | Mutation | Receptors, Notch - immunology | Myeloid Neoplasia
Journal Article
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 04/2018, Volume 141, Issue 4, pp. 1439 - 1449
Journal Article
Journal of Histochemistry and Cytochemistry, ISSN 0022-1554, 07/2006, Volume 54, Issue 7, pp. 763 - 771
CD163 is a member of the scavenger receptor cysteine-rich superfamily restricted to the monocyte/macrophage lineage and is thought to be a useful marker for... 
CD163 | NITRIC-OXIDE SYNTHASE | GIANT-CELL TUMOR | atherosclerotic lesions | MONOCLONAL-ANTIBODY | GLUCOCORTICOID-INDUCIBLE MEMBER | HUMAN MONOCYTES | CYSTEINE-RICH FAMILY | CELL BIOLOGY | macrophage heterogeneity | TUMOR-NECROSIS-FACTOR | DIFFERENTIATION ANTIGEN | MEMBRANE-PROTEIN RM3/1 | macrophage markers | granulomatous diseases | HEMOGLOBIN SCAVENGER RECEPTOR | Immunohistochemistry | Antigens, CD - immunology | Tuberculosis, Pulmonary - metabolism | Histiocytosis, Non-Langerhans-Cell - metabolism | Giant Cell Tumors - immunology | Antigens, CD - biosynthesis | Humans | Synovial Membrane - pathology | Histiocytosis, Sinus - metabolism | Giant Cell Tumors - metabolism | Antigens, CD - metabolism | Bone Neoplasms - metabolism | Paraffin Embedding | Soft Tissue Neoplasms - immunology | Histiocytosis, Sinus - immunology | Foreign-Body Reaction - immunology | Mass Spectrometry | Sarcoidosis - immunology | Cell Differentiation | Receptors, Cell Surface - biosynthesis | Antigens, Differentiation, Myelomonocytic - immunology | Histiocytosis, Non-Langerhans-Cell - immunology | Macrophages - immunology | Antigens, Differentiation, Myelomonocytic - biosynthesis | Atherosclerosis - immunology | Gaucher Disease - metabolism | Electrophoresis, Polyacrylamide Gel | Soft Tissue Neoplasms - metabolism | Foreign-Body Reaction - metabolism | Gaucher Disease - immunology | Receptors, Cell Surface - metabolism | Bone Neoplasms - immunology | Macrophages - cytology | Receptors, Cell Surface - immunology | Atherosclerosis - metabolism | Macrophage Activation | Macrophages - metabolism | Phenotype | Tuberculosis, Pulmonary - immunology | Antigens, Differentiation, Myelomonocytic - metabolism | Sarcoidosis - metabolism | Macrophage heterogeneity | Macrophage markers | Atherosclerotic lesions | Granulomatous diseases
Journal Article
Blood, ISSN 0006-4971, 07/2017, Volume 130, Issue 2, pp. 176 - 180
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2013, Volume 8, Issue 10, p. e76711
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening, virus-triggered immune disease. Hypersensitivity to mosquito bite (HMB), a presentation of... 
LINKED LYMPHOPROLIFERATIVE SYNDROME | NATURAL-KILLER-CELLS | EBV INFECTION | VIRAL-DNA | MULTIDISCIPLINARY SCIENCES | VIROLOGICAL CHARACTERISTICS | NK-CELLS | T-CELLS | DEFICIENCY | LYMPHOCYTES | CHILDREN | Immunoglobulins - immunology | Granzymes - metabolism | Humans | Hypersensitivity - immunology | Intracellular Signaling Peptides and Proteins - immunology | Male | CD4-Positive T-Lymphocytes - immunology | Insect Bites and Stings - genetics | Lymphocyte Activation - immunology | Flow Cytometry | Hypersensitivity - metabolism | Immunoglobulins - blood | CD8-Positive T-Lymphocytes - metabolism | Epstein-Barr Virus Infections - genetics | Killer Cells, Natural - immunology | Female | Hypersensitivity - genetics | Granzymes - immunology | Perforin - immunology | Lymphohistiocytosis, Hemophagocytic - genetics | Intracellular Signaling Peptides and Proteins - genetics | Lymphohistiocytosis, Hemophagocytic - immunology | Insect Bites and Stings - immunology | Membrane Proteins - genetics | Epstein-Barr Virus Infections - immunology | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Herpesvirus 4, Human - immunology | Membrane Proteins - immunology | Sequence Analysis, DNA | Animals | Culicidae - immunology | Signaling Lymphocytic Activation Molecule Associated Protein | Lymphohistiocytosis, Hemophagocytic - metabolism | Insect Bites and Stings - metabolism | K562 Cells | Perforin - metabolism | Killer Cells, Natural - metabolism | CD8-Positive T-Lymphocytes - immunology | Cytotoxicity, Immunologic - immunology | Epstein-Barr Virus Infections - metabolism | Infection | Medical research | Allergy | Mosquitoes | Killer cells | Bites and stings | Immunoglobulin E | Medicine, Experimental | Epstein-Barr virus | B cells | Health aspects | Allergic reaction | Pediatrics | Toxicity | CD8 antigen | Chronic infection | Cytotoxicity | Viruses | Oncology | Infections | Aquatic insects | Immunology | Lymphocytes | Gangrene | Perforin | Immunoglobulins | Immunological memory | Hematology | Hypersensitivity | Rheumatology | CD3 antigen | Histiocytosis | Patients | CD4 antigen | Asthma | Medicine | Convalescence | Ulcers | Histocompatibility antigen HLA | Mutation | Lymphocytosis
Journal Article
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 1/2012, Volume 69, Issue 1, pp. 29 - 40
Cytotoxic T lymphocytes, natural killer cells, and NKT cells are effector cells able to kill infected cells. In some inherited human disorders, a defect in... 
Life Sciences | Biochemistry, general | Life Sciences, general | Natural killer | Cellular cytotoxicity | Hemophagocytosis | Mutation analysis | Biomedicine general | Cell Biology | NATURAL-KILLER-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BONE-MARROW | LINKED LYMPHOPROLIFERATIVE-DISEASE | HERMANSKY-PUDLAK-SYNDROME | CUTTING EDGE | CELL BIOLOGY | GRISCELLI SYNDROME TYPE-2 | JUVENILE RHEUMATOID-ARTHRITIS | PERFORIN GENE-MUTATIONS | GENOTYPE-PHENOTYPE | PARTIAL ALBINISM | Pore Forming Cytotoxic Proteins - genetics | Humans | Cytotoxicity, Immunologic - physiology | Lymphoproliferative Disorders - immunology | Macrophage Activation Syndrome - immunology | Munc18 Proteins - immunology | Lymphocyte Subsets - immunology | Cytoplasmic Granules - metabolism | Killer Cells, Natural - immunology | Qa-SNARE Proteins - genetics | Macrophage Activation Syndrome - genetics | Immunologic Deficiency Syndromes - immunology | Lymphohistiocytosis, Hemophagocytic - genetics | Perforin | Chediak-Higashi Syndrome - genetics | Lymphohistiocytosis, Hemophagocytic - immunology | T-Lymphocytes, Cytotoxic - immunology | Munc18 Proteins - genetics | Membrane Proteins - genetics | Piebaldism - genetics | Lymphohistiocytosis, Hemophagocytic - diagnosis | Membrane Proteins - immunology | Lymphoproliferative Disorders - genetics | Lymphohistiocytosis, Hemophagocytic - therapy | Qa-SNARE Proteins - immunology | Hermanski-Pudlak Syndrome - immunology | Hermanski-Pudlak Syndrome - genetics | Animals | Chediak-Higashi Syndrome - immunology | Piebaldism - immunology | Pore Forming Cytotoxic Proteins - immunology | Immunologic Deficiency Syndromes - genetics | Mice | Natural Killer T-Cells - immunology | Proteins | Genetic aspects | International cooperation | T cells | Immunodeficiency | Lymphocyte receptors | Cytotoxicity | Models | Cells | Clinical trials | Effector cells | Lymphocytes T | Natural killer cells | Histiocytosis | Lymphocytosis
Journal Article
Journal Article
Respiratory Medicine, ISSN 0954-6111, 2016, Volume 119, pp. 168 - 174
Abstract Background The histologic diagnosis of Pulmonary Langerhans cell histiocytosis (PLCH) is invasive and can cause complications. To confirm the... 
Pulmonary/Respiratory | Langerhans cells | Flow cytometry | Pulmonary Langerhans cell histiocytosis (PLCH) | Dendritic cells | Bronchoalveolar lavage | Smoking | LUNG | CARDIAC & CARDIOVASCULAR SYSTEMS | MONOCLONAL-ANTIBODY | PHENOTYPES | AIRWAY DENDRITIC CELLS | IMPACT | DISEASES | FLUID | RESPIRATORY SYSTEM | SMOKERS | CO-STIMULATION | SURFACE | Antigens, CD - immunology | Flow Cytometry - methods | Prospective Studies | Immunoglobulins - immunology | Dendritic Cells - immunology | Humans | Middle Aged | Bronchoalveolar Lavage Fluid - immunology | Histiocytosis, Langerhans-Cell - diagnostic imaging | Male | Tomography, X-Ray Computed | Bronchoalveolar Lavage - methods | Lung - diagnostic imaging | Lung Diseases - diagnostic imaging | Histiocytosis, Langerhans-Cell - pathology | Adult | Female | Bronchoalveolar Lavage Fluid - cytology | Membrane Glycoproteins - immunology | Antigens, CD1 - immunology | Lung - pathology | Forced Expiratory Volume - physiology | Respiratory Function Tests - methods | Histiocytosis, Langerhans-Cell - immunology | Germany - epidemiology | Lung Diseases - immunology | Smoking - epidemiology | Biomarkers | Lung Diseases - pathology | Lung - immunology | Histiocytosis, Langerhans-Cell - complications | Histiocytosis | Analysis | Diagnosis | Immunoglobulins | Statistical analysis | Cysts | Laboratories | Metastasis | Cigarettes | Age
Journal Article