Articles

UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (21567) 21567
Book Chapter (252) 252
Book / eBook (9) 9
Newsletter (9) 9
Dissertation (4) 4
Publication (2) 2
Government Document (1) 1
Newspaper Article (1) 1
Web Resource (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (19250) 19250
life sciences & biomedicine (16996) 16996
humans (13645) 13645
animals (10590) 10590
histones - metabolism (7103) 7103
histone deacetylases - metabolism (6002) 6002
biochemistry & molecular biology (5655) 5655
cell biology (5413) 5413
mice (5201) 5201
gene expression (5140) 5140
acetylation (5000) 5000
chromatin (4196) 4196
proteins (3980) 3980
epigenetics (3897) 3897
histones (3579) 3579
histone deacetylase (3526) 3526
oncology (3484) 3484
cell line, tumor (3483) 3483
dna methylation (3422) 3422
male (3375) 3375
histone deacetylase inhibitors - pharmacology (3311) 3311
female (3245) 3245
research (3039) 3039
methylation (2817) 2817
cancer (2688) 2688
biological and medical sciences (2587) 2587
hydroxamic acids - pharmacology (2562) 2562
epigenesis, genetic (2404) 2404
genetic aspects (2363) 2363
histone deacetylase inhibitors (2274) 2274
histone deacetylases - genetics (2264) 2264
apoptosis (2254) 2254
science & technology - other topics (2191) 2191
multidisciplinary sciences (2175) 2175
genes (2108) 2108
genetics & heredity (2102) 2102
analysis (2066) 2066
cell line (2001) 2001
physiological aspects (1923) 1923
research article (1908) 1908
protein binding (1883) 1883
promoter regions, genetic (1844) 1844
chromatin - metabolism (1832) 1832
transcription, genetic (1795) 1795
repressor proteins - metabolism (1783) 1783
transcription factors - metabolism (1761) 1761
medical sciences (1746) 1746
deoxyribonucleic acid--dna (1737) 1737
signal transduction (1710) 1710
cells, cultured (1673) 1673
mutation (1662) 1662
gene expression regulation (1650) 1650
biology (1649) 1649
enzymes (1594) 1594
epigenetic inheritance (1579) 1579
tumors (1570) 1570
genetics (1530) 1530
apoptosis - drug effects (1506) 1506
cell cycle (1504) 1504
transcription (1499) 1499
enzyme inhibitors - pharmacology (1472) 1472
medicine (1410) 1410
histones - genetics (1409) 1409
dna (1399) 1399
phosphorylation (1377) 1377
dna-binding proteins - metabolism (1359) 1359
rats (1336) 1336
pharmacology & pharmacy (1330) 1330
neurosciences (1310) 1310
health aspects (1287) 1287
gene silencing (1247) 1247
antineoplastic agents - pharmacology (1246) 1246
kinases (1239) 1239
science (1236) 1236
neurosciences & neurology (1216) 1216
cell proliferation - drug effects (1194) 1194
transcription factors (1171) 1171
mice, inbred c57bl (1147) 1147
molecular sequence data (1123) 1123
cell proliferation (1114) 1114
fundamental and applied biological sciences. psychology (1110) 1110
acetylation - drug effects (1106) 1106
repressor proteins - genetics (1105) 1105
blotting, western (1103) 1103
transcription factors - genetics (1090) 1090
gene expression regulation, neoplastic (1069) 1069
binding sites (1049) 1049
molecular biology (1045) 1045
genomes (1043) 1043
lysine (1042) 1042
protein processing, post-translational (1032) 1032
stem cells (1031) 1031
histone acetylation (1029) 1029
genetic transcription (1022) 1022
nuclear proteins - metabolism (1010) 1010
life sciences (1009) 1009
rna, messenger - metabolism (991) 991
histone modification (990) 990
amino acid sequence (947) 947
cell differentiation (908) 908
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (21810) 21810
Japanese (88) 88
Chinese (53) 53
German (23) 23
French (11) 11
Russian (9) 9
Portuguese (5) 5
Polish (3) 3
Spanish (2) 2
Croatian (1) 1
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase–mediated suppression of histone deacetylase 2
by Kim, Richard Y., PhD and Horvat, Jay C., PhD and Pinkerton, James W., B Biomed Sci and Starkey, Malcolm R., PhD and Essilfie, Ama T., PhD and Mayall, Jemma R., B Biomed Sci and Nair, Prema M., B Biomed Sci and Hansbro, Nicole G., PhD and Jones, Bernadette, BSc and Haw, Tatt Jhong, B Biomed Sci and Sunkara, Krishna P., MSc and Nguyen, Thi Hiep, MSc and Jarnicki, Andrew G., PhD and Keely, Simon, PhD and Mattes, Joerg, MD, PhD and Adcock, Ian M., PhD and Foster, Paul S., DSc and Hansbro, Philip M., PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2016, Volume 139, Issue 2, pp. 519 - 532
Allergy and Immunology | influenza | airway hyperresponsiveness | corticosteroids | PI3 kinase | Chlamydia species | histone deacetylase 2 | miR-21 | Severe asthma | respiratory syncytial virus | Haemophilus influenzae | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Influenza A Virus, H1N1 Subtype - immunology | Phosphorylation | Humans | Respiratory Syncytial Viruses - immunology | MicroRNAs - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Respiratory Tract Infections - genetics | Chlamydia muridarum - immunology | Asthma - immunology | Pneumonia - immunology | Proto-Oncogene Proteins c-akt - metabolism | Drug Resistance | Disease Models, Animal | Pneumonia - genetics | Histone Deacetylase 2 - genetics | PTEN Phosphohydrolase - genetics | Gene Expression Regulation | PTEN Phosphohydrolase - metabolism | Respiratory Tract Infections - drug therapy | Asthma - drug therapy | Asthma - genetics | Dexamethasone - therapeutic use | Animals | Pneumonia - drug therapy | Haemophilus influenzae - immunology | Respiratory Tract Infections - immunology | Mice | Mice, Inbred BALB C | MicroRNAs - genetics | Histone Deacetylase 2 - metabolism | Antagomirs - genetics | MicroRNA | Research institutes | Analysis | Asthma | Therapeutics | Health aspects | Homeopathy | Materia medica and therapeutics | Respiratory syncytial virus | Pathogenesis | Rodents | Influenza | Tumor necrosis factor-TNF | Chronic obstructive pulmonary disease | Infections | Inflammation | Viral infections | Steroids | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text S -nitrosylation of histone deacetylase 2 induces chromatin remodelling in neurons
by Watson, P. Marc and Robinson, James D and Crepaldi, Luca and Nott, Alexi and Riccio, Antonella
Nature (London), ISSN 0028-0836, 09/2008, Volume 455, Issue 7211, pp. 411 - 415
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Vertebrates: nervous system and sense organs | Biological and medical sciences | General aspects. Models. Methods | Chromatin - metabolism | Dendrites - metabolism | Nitric Oxide - biosynthesis | Histone Deacetylases - genetics | Chromatin Assembly and Disassembly | Rats | Repressor Proteins - genetics | Cytoplasm - metabolism | Histone Deacetylase 2 | Histone Deacetylases - metabolism | Male | Neurons - cytology | Nuclear Proteins - metabolism | Nerve Growth Factors - metabolism | Brain-Derived Neurotrophic Factor - pharmacology | Animals | Neurons - enzymology | Female | Cysteine - metabolism | Mice | Neurons - metabolism | Nitric Oxide - metabolism | Repressor Proteins - metabolism | Histones | Physiological aspects | Chromatin | Research | Neurons | Proteins | Changes | Nervous system | Influence | Genetic engineering | Gene expression | Cells | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text The NAD(+)-dependent Histone Deacetylase SIRT6 Promotes Cytokine Production and Migration in Pancreatic Cancer Cells by Regulating Ca2+ Responses
by Bauer, Inga and Grozio, Alessia and Lasiglie, Denise and Basile, Giovanna and Sturla, Laura and Magnone, Mirko and Sociali, Giovanna and Soncini, Debora and Caffa, Irene and Poggi, Alessandro and Zoppoli, Gabriele and Cea, Michele and Feldmann, Georg and Mostoslavsky, Raul and Ballestrero, Alberto and Patrone, Franco and Bruzzone, Santina and Nencioni, Alessio
The Journal of biological chemistry, ISSN 0021-9258, 11/2012, Volume 287, Issue 49, pp. 40924 - 40937
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Pancreatic Neoplasms - metabolism | Cytokines - metabolism | Signal Transduction | Calcium - metabolism | Humans | Gene Expression Regulation, Neoplastic | Histone Deacetylases - metabolism | NF-kappa B - metabolism | Inflammation | Gene Expression Regulation, Enzymologic | Animals | Retroviridae - metabolism | Cell Line, Tumor | Mice | Interleukin-8 - metabolism | Sirtuins - metabolism | NAD - metabolism | Cell Movement | RNA, Small Interfering - metabolism | Index Medicus | NAD | Sirtuins | Signaling | Cytokines | Cancer
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6
by Zhang, Qian and Zhao, Kai and Shen, Qicong and Han, Yanmei and Gu, Yan and Li, Xia and Zhao, Dezhi and Liu, Yiqi and Wang, Chunmei and Zhang, Xiang and Su, Xiaoping and Liu, Juan and Ge, Wei and Levine, Ross L and Li, Nan and Cao, Xuetao
Nature (London), ISSN 0028-0836, 09/2015, Volume 525, Issue 7569, pp. 389 - 393
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Chromatin - metabolism | Interleukin-6 - antagonists & inhibitors | Histones - chemistry | Epigenesis, Genetic | Humans | Male | I-kappa B Proteins - metabolism | Promoter Regions, Genetic - genetics | DNA-Binding Proteins - deficiency | DNA-Binding Proteins - metabolism | DNA Methylation | Inflammation - metabolism | HEK293 Cells | Female | Transcription, Genetic | Acetylation | Colitis - immunology | Dendritic Cells - metabolism | Chromatin - chemistry | Proto-Oncogene Proteins - metabolism | Interleukin-6 - genetics | Mice, Inbred C57BL | Inflammation - immunology | Proto-Oncogene Proteins - deficiency | Down-Regulation - genetics | Macrophages - metabolism | Animals | Colitis - enzymology | Colitis - metabolism | Interleukin-6 - immunology | Interleukin-6 - biosynthesis | Dendritic Cells - cytology | Mice | Histone Deacetylase 2 - metabolism | Histones - metabolism | Chromatin - genetics | Inflammation - enzymology | Enzymes | Genetic aspects | Inflammation | Health aspects | Interleukin-6 | Proteins | Cytokines | Dendritic cells | Pathogenesis | Rodents | DNA methylation | Epigenetics | Gene expression | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor
by Tadahiro Shimazu and Matthew D. Hirschey and John Newman and Wenjuan He and Kotaro Shirakawa and Natacha Le Moan and Carrie A. Grueter and Hyungwook Lim and Laura R. Saunders and Robert D. Stevens and Christopher B. Newgard and Robert V. Farese and Rafael de Cabo and Scott Ulrich and Katerina Akassoglou and Eric Verdin
Science (American Association for the Advancement of Science), ISSN 0036-8075, 1/2013, Volume 339, Issue 6116, pp. 211 - 214
Oxidative stress | Kidneys | Fasting | HEK293 cells | Pumps | Genes | REPORTS | Histones | Immunoblotting | Acetylation | T tests | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Metallothionein - metabolism | Caloric Restriction | Humans | Transcriptional Activation | Histone Deacetylase Inhibitors - blood | Kidney - metabolism | HEK293 Cells | Transcription, Genetic | Superoxide Dismutase - metabolism | Promoter Regions, Genetic | Kidney - drug effects | Histone Deacetylases - genetics | 3-Hydroxybutyric Acid - blood | Mice, Inbred C57BL | Oxidative Stress - genetics | Histone Deacetylases - metabolism | Forkhead Transcription Factors - genetics | Catalase - metabolism | Animals | Metallothionein - genetics | 3-Hydroxybutyric Acid - metabolism | Histone Deacetylase Inhibitors - pharmacology | Mice | RNA, Small Interfering | Histones - metabolism | 3-Hydroxybutyric Acid - pharmacology | Forkhead Box Protein O3 | Histone Deacetylase Inhibitors - metabolism | Lipid Peroxidation | Index Medicus | Stresses | Stress concentration | Poisons | Fatty acids
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text The histone deacetylase SIRT2 stabilizes Myc oncoproteins
by Liu, P.Y and Xu, N and Malyukova, A and Scarlett, C.J and Sun, Y.T and Zhang, X.D and Ling, D and Su, S.-P and Nelson, C and Chang, D.K and Koach, J and Tee, A.E and Haber, M and Norris, M.D and Toon, C and Rooman, I and Xue, C and Cheung, B.B and Kumar, S and Marshall, G.M and Biankin, A.V and Liu, T
Cell death and differentiation, ISSN 1350-9047, 2013, Volume 20, Issue 3, pp. 503 - 514
N-Myc | neuroblastoma | pancreatic cancer | histone deacetylase | NEDD4 | SIRT2 | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Phosphorylation | Cell Proliferation | Humans | RNA, Messenger - metabolism | Sirtuin 2 - metabolism | Ubiquitination | RNA Interference | Nedd4 Ubiquitin Protein Ligases | Sirtuin 2 - antagonists & inhibitors | Protein Stability | Protein-Serine-Threonine Kinases - metabolism | Gene Expression | Endosomal Sorting Complexes Required for Transport | Naphthols - pharmacology | Protein-Serine-Threonine Kinases - genetics | Aurora Kinases | Proto-Oncogene Proteins c-myc - metabolism | Ubiquitin-Protein Ligases | Up-Regulation - drug effects | Phenylpropionates - pharmacology | Sirtuin 2 - genetics | Proto-Oncogene Proteins c-myc - antagonists & inhibitors | Cell Line, Tumor | Protein Binding | Proto-Oncogene Proteins c-myc - genetics | RNA, Small Interfering - metabolism | Index Medicus | Original Paper | Medicin och hälsovetenskap
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Antidepressant Actions of Histone Deacetylase Inhibitors
by Covington, Herbert E., III and Maze, Ian and LaPlant, Quincey C and Vialou, Vincent F and Ohnishi, Yoshinori N and Berton, Olivier and Fass, Dan M and Renthal, William and Rush, Augustus J., III and Wu, Emma Y and Ghose, Subroto and Krishnan, Vaishnav and Russo, Scott J and Tamminga, Carol and Haggarty, Stephen J and Nestler, Eric J
The Journal of neuroscience, ISSN 0270-6474, 09/2009, Volume 29, Issue 37, pp. 11451 - 11460
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Gene Expression Regulation, Enzymologic - drug effects | Depression - pathology | Humans | Sucrose - pharmacology | Male | Gene Expression Regulation, Enzymologic - physiology | RNA, Messenger - metabolism | Repressor Proteins - antagonists & inhibitors | Dose-Response Relationship, Drug | Depression - drug therapy | Dominance-Subordination | Nucleus Accumbens - enzymology | Behavior, Animal - drug effects | Antidepressive Agents - pharmacology | Benzamides - pharmacology | Interpersonal Relations | Repressor Proteins - metabolism | Disease Models, Animal | Fluoxetine - pharmacology | Histone Deacetylases - genetics | Sweetening Agents - pharmacology | Food Preferences - drug effects | Oligonucleotide Array Sequence Analysis - methods | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Repressor Proteins - genetics | Gene Expression Profiling - methods | Histone Deacetylase 2 | Histone Deacetylases - metabolism | Depression - enzymology | Hydroxamic Acids | Animals | Histones - genetics | Analysis of Variance | Models, Biological | Vorinostat | Histone Deacetylase Inhibitors | Mice | Pyridines - pharmacology | Histones - metabolism | Nucleus Accumbens - drug effects | Postmortem Changes | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Activation of the protein deacetylase SIRT6 by long-chain fatty acids and widespread deacylation by Mammalian Sirtuins
by Feldman, Jessica L and Baeza, Josue and Denu, John M
The Journal of biological chemistry, ISSN 0021-9258, 10/2013, Volume 288, Issue 43, pp. 31350 - 31356
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Sirtuin 1 - metabolism | Lipoylation - physiology | Sirtuin 3 - genetics | Sirtuin 3 - metabolism | Humans | Sirtuin 1 - genetics | Sirtuin 2 - metabolism | Hydrolysis | Sirtuin 2 - genetics | Histones - genetics | Acylation - physiology | Histones - metabolism | Sirtuins - genetics | Enzyme Activation - physiology | Fatty Acids - metabolism | Sirtuins - metabolism | Index Medicus | Gene Regulation | Sirtuins | Fatty Acids | coA | Post-translational Modification | Reports | Metabolism | Polyunsaturated Fatty Acids | Enzymology | Histone Deacetylase
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Selective inhibition of class I but not class IIb histone deacetylases exerts cardiac protection from ischemia reperfusion
by Aune, Sverre E and Herr, Daniel J and Mani, Santhosh K and Menick, Donald R
Journal of molecular and cellular cardiology, ISSN 0022-2828, 2014, Volume 72, pp. 138 - 145
Cardiovascular | Histone deacetylase | FOXO | Superoxide dismutase | Isolated heart | Catalase | Ischemia reperfusion | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Cell Biology | Superoxide Dismutase - genetics | Myocardial Contraction - drug effects | Male | Myocardial Reperfusion Injury - enzymology | Forkhead Transcription Factors - metabolism | Histone Deacetylase 1 - antagonists & inhibitors | Indoles - pharmacology | Benzamides - pharmacology | Histone Deacetylase 1 - genetics | Hydroxamic Acids - pharmacology | Myocardial Reperfusion Injury - genetics | Organ Culture Techniques | Superoxide Dismutase - metabolism | Heart - physiopathology | Histone Deacetylase 2 - genetics | Histone Deacetylases - genetics | Catalase - genetics | Histone Deacetylase 2 - antagonists & inhibitors | Histone Deacetylase 6 | Gene Expression Regulation | Rats | Histone Deacetylases - metabolism | Forkhead Transcription Factors - genetics | Rats, Sprague-Dawley | Myocardial Reperfusion Injury - physiopathology | Catalase - metabolism | Animals | Heart - drug effects | Histone Deacetylase Inhibitors - pharmacology | Pyridines - pharmacology | Histone Deacetylase 2 - metabolism | Forkhead Box Protein O3 | Myocardial Reperfusion Injury - prevention & control | Histone Deacetylase 1 - metabolism | Antioxidants | Ischemia | Superoxide | Index Medicus | ischemia reperfusion | isolated heart | histone deacetylase | superoxide dismutase | catalase
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Sequential treatment with 5‐aza‐2