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Molecules (Basel, Switzerland), ISSN 1420-3049, 03/2018, Volume 23, Issue 3, p. 566
.... These newly identified inhibitors were further tested against human histone deacetylases (hsHDAC1, 6 and 8), and were found also to be exerting interesting activity against... 
Epigenetics | Virtual screening | Histone deacetylase (HDAC) inhibitors | Schistosomiasis | Docking | Crystal structure | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Apoptosis - drug effects | Zinc - metabolism | Helminth Proteins - chemistry | Anthelmintics - chemical synthesis | Crystallography, X-Ray | Structure-Activity Relationship | Zinc - chemistry | Schistosoma mansoni - genetics | Pyrrolidines - pharmacology | Histone Deacetylase Inhibitors - chemical synthesis | Protein Interaction Domains and Motifs | Schistosoma mansoni - growth & development | Binding Sites | Helminth Proteins - metabolism | Hydroxamic Acids - pharmacology | Schistosoma mansoni - drug effects | Gene Expression | Histone Deacetylases - genetics | Protein Structure, Secondary | Schistosoma mansoni - enzymology | Histone Deacetylases - chemistry | Histone Deacetylases - metabolism | Helminth Proteins - genetics | Chelating Agents - pharmacology | Animals | Pyrrolidines - chemical synthesis | Anthelmintics - pharmacology | Protein Binding | Histone Deacetylase Inhibitors - pharmacology | Molecular Docking Simulation | Chelating Agents - chemical synthesis | Hydroxamic Acids - chemical synthesis | Helminth Proteins - antagonists & inhibitors | Histone deacetylase | Screening | Chromatin | Inhibitors | Catalysis | In vitro methods and tests | Chelates | Zinc | Index Medicus | Chelating Agents/pharmacology | Helminth Proteins/antagonists & inhibitors | Schistosoma mansoni/enzymology | Pyrrolidines/pharmacology | Life Sciences | Histone Deacetylases/genetics | Anthelmintics/chemical synthesis | Schistosoma mansoni/genetics | Helminth Proteins/genetics | Biomolecules | Histone Deacetylase Inhibitors/chemical synthesis | Chelating Agents/chemical synthesis | Pyrrolidines/chemical synthesis | Schistosoma mansoni/growth & development | Hydroxamic Acids/chemical synthesis | Zinc/chemistry | Biochemistry, Molecular Biology | Apoptosis/drug effects | Helminth Proteins/metabolism | Histone Deacetylases/chemistry | Hydroxamic Acids/pharmacology | Anthelmintics/pharmacology | Schistosoma mansoni/drug effects | Histone Deacetylases/metabolism | Helminth Proteins/chemistry | Histone Deacetylase Inhibitors/pharmacology | Zinc/metabolism | crystal structure | docking | virtual screening | histone deacetylase (HDAC) inhibitors | schistosomiasis | epigenetics
Journal Article
2019, ISBN 981138018X, 101
...) and histone deacetylases (HDACs). It chiefly focuses on the emerging targets of HDACs and their implications for various neurological disorders, while also discussing the drawbacks of current therapeutic strategies... 
Histone deacetylase-Inhibitors-Therapeutic use | Protein Science | Neurosciences | Biomedicine | Genetics and Genomics | Biomedical and Life Sciences | Pharmacology/Toxicology | Posttranslational Modification
eBook
Journal of cellular biochemistry, ISSN 1097-4644, 07/2009, Volume 107, Issue 4, pp. 600 - 608
Journal Article
ChemMedChem, ISSN 1860-7179, 01/2016, Volume 11, Issue 1, pp. 15 - 21
Hydroxamate‐based histone deacetylase inhibitors (HDACIs) have been approved as therapeutic agents by the US Food and Drug Administration for use in oncology applications... 
mutagenicity | Lossen rearrangement | hydroxamate | histone deacetylase inhibitors | Humans | Hydroxamic Acids - chemistry | Histone Deacetylase Inhibitors - pharmacology | Histone Deacetylases - metabolism | Molecular Structure | Histone Deacetylase Inhibitors - chemistry | Drug Discovery | Hydroxamic Acids - pharmacology | Pharmaceutical industry | Genes | Index Medicus
Journal Article