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Journal of Clinical Oncology, ISSN 0732-183X, 11/2009, Volume 27, Issue 32, pp. 5410 - 5417
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 08/2015, Volume 33, Issue 23, pp. 2492 - 2499
Journal Article
Journal Article
Circulation, ISSN 0009-7322, 03/2014, Volume 129, Issue 10, pp. 1139 - 1151
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2016, Volume 113, Issue 46, pp. 13162 - 13167
Multiple myeloma (MM) has proven clinically susceptible to modulation of pathways of protein homeostasis. Blockade of proteasomal degradation of... 
Bortezomib-resistance | Histone deacetylase 6 | Proteasome inhibitor | Multiple myeloma | WT161 | PRECLINICAL ACTIVITY | CANCER-CELLS | APOPTOSIS | multiple myeloma | DEXAMETHASONE | MULTICENTER | histone deacetylase 6 | ER STRESS | MULTIDISCIPLINARY SCIENCES | KINASE | BORTEZOMIB | ANTITUMOR-ACTIVITY | proteasome inhibitor | bortezomib-resistance | HISTONE DEACETYLASE INHIBITORS | Anilides - therapeutic use | Terphenyl Compounds - therapeutic use | Humans | Drug Resistance, Neoplasm | Male | Antineoplastic Agents - therapeutic use | Bortezomib - pharmacology | Terphenyl Compounds - pharmacology | Histone Deacetylase 6 - metabolism | Multiple Myeloma - drug therapy | Tubulin - metabolism | Antineoplastic Agents - pharmacology | Tumor Cells, Cultured | Hydroxamic Acids - pharmacology | Cell Survival - drug effects | Proteasome Inhibitors - pharmacology | Histone Deacetylase 6 - antagonists & inhibitors | Multiple Myeloma - metabolism | Proteasome Inhibitors - therapeutic use | Animals | Bortezomib - therapeutic use | Anilides - pharmacology | Cell Line, Tumor | Histone Deacetylase Inhibitors - pharmacology | Hydroxamic Acids - therapeutic use | Histone Deacetylase Inhibitors - therapeutic use | Mice | Protein folding | Homeostasis | Clinical trials | Cytotoxicity | Pharmacology | Drug resistance | Index Medicus | Biological Sciences
Journal Article
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 01/2012, Volume 18, Issue 2, pp. 408 - 416
Journal Article
Circulation, ISSN 0009-7322, 07/2012, Volume 126, Issue 4, pp. 455 - 467
Background-Epigenetic programming, dynamically regulated by histone acetylation, is a key mechanism regulating cell proliferation and survival. Little is known... 
genetic | epigenesis | vorinostat | histone deacetylation | pulmonary | valproic acid | hypertension | TARGET | CELLS | APOPTOSIS | CARDIAC & CARDIOVASCULAR SYSTEMS | ACETYLATION | hypertension, pulmonary | epigenesis, genetic | PROLIFERATION | EMERGENCE | ARTERIAL-HYPERTENSION | PROSTATE-CANCER | IN-VIVO | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | EXPRESSION | Muscle, Smooth, Vascular - metabolism | Humans | Male | Valproic Acid - pharmacology | Pulmonary Artery - metabolism | Histone Deacetylase 1 - antagonists & inhibitors | Valproic Acid - therapeutic use | Hypertension, Pulmonary - drug therapy | Lung - metabolism | Hydroxamic Acids - pharmacology | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Lung - pathology | Cells, Cultured | Rats | Histone Deacetylases - metabolism | Hypertension, Pulmonary - metabolism | Hypoxia - complications | Platelet-Derived Growth Factor - pharmacology | Pulmonary Artery - drug effects | Rats, Sprague-Dawley | Muscle, Smooth, Vascular - pathology | Animals | Lung - drug effects | Histone Deacetylase Inhibitors - pharmacology | Histone Deacetylases - drug effects | Hydroxamic Acids - therapeutic use | Cell Proliferation - drug effects | Histone Deacetylase Inhibitors - therapeutic use | Hypertension, Pulmonary - etiology | Pulmonary Artery - pathology | Histone Deacetylase 1 - metabolism | Cell proliferation | Divalproex | Care and treatment | Usage | Enzyme inhibitors | Physiological aspects | Research | Valproic acid | Health aspects | Pulmonary hypertension | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
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