X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (3517) 3517
histone-lysine n-methyltransferase - metabolism (2258) 2258
animals (2242) 2242
histone-lysine n-methyltransferase - genetics (2181) 2181
methylation (1941) 1941
histone-lysine n-methyltransferase (1573) 1573
histones - metabolism (1562) 1562
mice (1321) 1321
biochemistry & molecular biology (1250) 1250
cell biology (1196) 1196
female (1191) 1191
male (1177) 1177
chromatin (1112) 1112
dna-binding proteins - genetics (965) 965
oncology (965) 965
gene expression (898) 898
dna methylation (861) 861
genetics & heredity (839) 839
myeloid-lymphoid leukemia protein - genetics (820) 820
research (813) 813
proteins (772) 772
genetic aspects (764) 764
cancer (683) 683
expression (676) 676
histones (673) 673
hematology (671) 671
mutation (639) 639
transcription factors (632) 632
genes (630) 630
epigenetics (626) 626
cell line, tumor (599) 599
myeloid-lymphoid leukemia protein (582) 582
transcription (559) 559
transcription factors - genetics (558) 558
molecular sequence data (546) 546
methyltransferases (531) 531
epigenesis, genetic (528) 528
gene-expression (527) 527
gene (523) 523
nuclear proteins - genetics (518) 518
lysine - metabolism (517) 517
leukemia (497) 497
proto-oncogenes (493) 493
dna-binding proteins - metabolism (488) 488
histones - genetics (488) 488
protein binding (483) 483
lysine (472) 472
physiological aspects (461) 461
amino acid sequence (457) 457
multidisciplinary sciences (452) 452
transcription factors - metabolism (452) 452
adult (444) 444
translocation, genetic (440) 440
histone methyltransferase (438) 438
transcription, genetic (436) 436
analysis (418) 418
acute myeloid-leukemia (415) 415
methyltransferase (412) 412
protein (409) 409
chromatin - metabolism (393) 393
histone h3 (391) 391
middle aged (386) 386
nuclear proteins - metabolism (383) 383
cell line (382) 382
dna (373) 373
genetics (368) 368
gene silencing (361) 361
infant (359) 359
gene expression regulation (358) 358
myeloid-lymphoid leukemia protein - metabolism (349) 349
research article (349) 349
histone-lysine n-methyltransferase - chemistry (347) 347
base sequence (344) 344
gene expression regulation, neoplastic (339) 339
repressor proteins - metabolism (334) 334
promoter regions, genetic (333) 333
mll (331) 331
gene rearrangement (325) 325
biology (323) 323
protein methyltransferases (321) 321
leukemia, myeloid, acute - genetics (320) 320
repressor proteins - genetics (310) 310
developmental biology (309) 309
histone methylation (308) 308
molecular biology (303) 303
aged (302) 302
histone-lysine n-methyltransferase - antagonists & inhibitors (296) 296
genomics (294) 294
child (292) 292
epigenetic inheritance (287) 287
acute lymphoblastic-leukemia (286) 286
acetylation (285) 285
cell proliferation (283) 283
cells, cultured (280) 280
precursor cell lymphoblastic leukemia-lymphoma - genetics (279) 279
complex (278) 278
histones - chemistry (275) 275
cells (272) 272
mice, inbred c57bl (272) 272
oncogene proteins, fusion - genetics (271) 271
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (4922) 4922
Chinese (40) 40
Japanese (33) 33
French (16) 16
Russian (5) 5
Korean (4) 4
Czech (2) 2
German (1) 1
Hungarian (1) 1
Polish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Nature (London), ISSN 1476-4687, 2010, Volume 464, Issue 7290, pp. 927 - 931
Journal Article
Molecular Oncology, ISSN 1574-7891, 12/2016, Volume 10, Issue 10, pp. 1497 - 1515
.... There is accumulating evidence that genetic alterations of several HMTs impinge on oncogenic or tumor-suppressor functions and influence both cancer initiation and progression... 
Histone methyltransferase | Chromatin | Breast cancer | Inhibitors | Transcription | SELECTIVE-INHIBITION | DNA METHYLATION | TUMOR-SUPPRESSOR GENE | TRANSCRIPTIONAL REPRESSION | CELL-PROLIFERATION | MESENCHYMAL TRANSITION | POTENT ANTITUMOR-ACTIVITY | LYSINE METHYLTRANSFERASE | ONCOLOGY | POOR-PROGNOSIS | PROTEIN ARGININE METHYLTRANSFERASES | Humans | Transcriptional Activation - drug effects | Protein-Arginine N-Methyltransferases - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Histone-Lysine N-Methyltransferase - analysis | Molecular Targeted Therapy | Breast Neoplasms - metabolism | Histone-Lysine N-Methyltransferase - antagonists & inhibitors | Histone Code - drug effects | Female | Antineoplastic Agents - pharmacology | Epigenesis, Genetic - drug effects | Protein-Arginine N-Methyltransferases - genetics | Gene Expression Regulation, Neoplastic - drug effects | Breast - pathology | Histone-Lysine N-Methyltransferase - genetics | Protein-Arginine N-Methyltransferases - analysis | Enzyme Inhibitors - pharmacology | Breast Neoplasms - drug therapy | Drug Discovery | Enzyme Inhibitors - therapeutic use | Protein-Arginine N-Methyltransferases - metabolism | Animals | Breast Neoplasms - genetics | Histone-Lysine N-Methyltransferase - metabolism | Breast - drug effects | Breast Neoplasms - pathology | Care and treatment | Methyltransferases | Lysine | Stem cells | Genetic transcription | Methylation | Cancer | CRISPR | Medical research | Genomes | Gene expression | Arginine | DNA methylation | Tumorigenesis | Binding sites | Deoxyribonucleic acid--DNA | Tumors | Review
Journal Article
Journal Article
Nature (London), ISSN 1476-4687, 2015, Volume 520, Issue 7546, pp. 243 - 247
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 2012, Volume 122, Issue 4, pp. 1469 - 1486
Breast cancers are highly heterogeneous but can be grouped into subtypes based on several criteria, including level of expression of certain markers.... 
EPITHELIAL-MESENCHYMAL TRANSITION | MEDICINE, RESEARCH & EXPERIMENTAL | BASAL-LIKE | STEM-CELLS | DNA METHYLATION | CLAUDIN-LOW | TRANSCRIPTION FACTOR SNAIL | GENE-EXPRESSION | PHENOTYPE | TUMOR-CELLS | HISTONE METHYLATION | Histocompatibility Antigens - genetics | Neoplasm Transplantation | Adenocarcinoma - pathology | Humans | Middle Aged | Neoplasm Proteins - physiology | Recombinant Fusion Proteins - physiology | Neoplasm Proteins - antagonists & inhibitors | Cell Line, Tumor - transplantation | Gene Expression Profiling | Cadherins - biosynthesis | Breast Neoplasms - metabolism | Gene Knockdown Techniques | DNA (Cytosine-5-)-Methyltransferases - metabolism | DNA Methylation | Histone-Lysine N-Methyltransferase - antagonists & inhibitors | Adenocarcinoma - metabolism | Adult | Female | Cadherins - genetics | Neoplasm Proteins - genetics | Cell Line, Tumor - metabolism | Snail Family Transcription Factors | Gene Expression Regulation, Neoplastic - genetics | Histone-Lysine N-Methyltransferase - genetics | Transcription Factors - physiology | DNA (Cytosine-5-)-Methyltransferase 1 | Neoplasm Invasiveness | Histocompatibility Antigens - physiology | Transcription Factors - genetics | Mice, Inbred ICR | Animals | Histone-Lysine N-Methyltransferase - metabolism | Breast Neoplasms - pathology | Aged | Mice | Protein Processing, Post-Translational | Histones - metabolism | Methylation | Histone-Lysine N-Methyltransferase - physiology | Physiological aspects | Cadherins | Breast cancer | Genetic aspects | Research | Transforming growth factors
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2013, Volume 110, Issue 42, pp. 16778 - 16783
Protein methyltransferase (PMT)-mediated posttranslational modification of histone and nonhistone substrates modulates stability, localization, and interacting... 
Proteins | Enzymes | DNA | Proteomics | Reagents | Histones | Biochemistry | Predetermined motion time systems | Methylation | Chemicals | Bump-hole | Posttranslation | Epigenetic | AZIDES | proteomics | SPECIFICITY | epigenetic | MULTIDISCIPLINARY SCIENCES | GLP | ALKYNES | HISTONES | G9A | ADENOSYL-L-METHIONINE | LYSINE METHYLTRANSFERASE | BIOLOGY | bump-hole | posttranslation | BINDING | Histocompatibility Antigens - genetics | Neoplasms - metabolism | Humans | Histocompatibility Antigens - chemistry | Substrate Specificity | Intracellular Signaling Peptides and Proteins - metabolism | S-Adenosylmethionine - chemistry | Neoplasm Proteins - metabolism | Neoplasms - chemistry | Neoplasms - genetics | HEK293 Cells | Protein-Arginine N-Methyltransferases - genetics | S-Adenosylmethionine - genetics | Histocompatibility Antigens - metabolism | Neoplasm Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Protein-Arginine N-Methyltransferases - chemistry | Histone-Lysine N-Methyltransferase - genetics | Neoplasm Proteins - chemistry | Protein-Arginine N-Methyltransferases - metabolism | Histone-Lysine N-Methyltransferase - chemistry | Histone-Lysine N-Methyltransferase - metabolism | Intracellular Signaling Peptides and Proteins - chemistry | Hydrophobic and Hydrophilic Interactions | S-Adenosylmethionine - metabolism | Post-translational modification | Physiological aspects | Protein biosynthesis | Research | Biological Sciences | Physical Sciences
Journal Article