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Nature neuroscience, ISSN 1546-1726, 2012, Volume 15, Issue 11, pp. 1488 - 1497
FUS/TLS (fused in sarcoma/translocated in liposarcoma) and TDP-43 are integrally involved in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia.... 
NEURODEGENERATIVE DISEASE | GENE | AMYOTROPHIC-LATERAL-SCLEROSIS | FAMILY PROTEINS | FUS PATHOLOGY | MUTATIONS | FRONTOTEMPORAL LOBAR DEGENERATION | BINDING | NEUROSCIENCES | BRAIN | NASCENT TRANSCRIPTION | RNA, Small Interfering - genetics | Protein Binding - genetics | Oligonucleotide Array Sequence Analysis | Humans | tau Proteins - metabolism | Gene Expression Profiling | RNA, Messenger - metabolism | Kv Channel-Interacting Proteins - metabolism | Brain - metabolism | Frontotemporal Dementia - metabolism | RNA Splicing - genetics | Frontotemporal Dementia - genetics | RNA-Binding Protein FUS - deficiency | Amyotrophic Lateral Sclerosis - genetics | Cell Cycle Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | RNA-Binding Protein FUS - genetics | Mice, Knockout | Motor Neurons - metabolism | Amyotrophic Lateral Sclerosis - pathology | Shal Potassium Channels - metabolism | Brain - pathology | Mice | Neurofilament Proteins - metabolism | RNA, Small Interfering - metabolism | Immunoprecipitation | Spinal Cord - metabolism | DNA-Binding Proteins - deficiency | DNA-Binding Proteins - metabolism | tau Proteins - genetics | Cell Cycle Proteins - genetics | Female | RNA Precursors - metabolism | Excitatory Amino Acid Transporter 2 - genetics | Membrane Proteins - metabolism | Frontotemporal Dementia - pathology | Gene Expression Regulation - genetics | Mice, Inbred C57BL | RNA, Messenger - genetics | RNA Precursors - genetics | Protein Structure, Tertiary - genetics | RNA-Binding Protein FUS - metabolism | DNA-Binding Proteins - genetics | Excitatory Amino Acid Transporter 2 - metabolism | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Histone-Lysine N-Methyltransferase - metabolism | Amyotrophic Lateral Sclerosis - metabolism | Neural Cell Adhesion Molecules - metabolism | Neural Stem Cells - metabolism | Cell Line, Transformed | Amyotrophic lateral sclerosis | Development and progression | Genetic aspects | Messenger RNA | Health aspects
Journal Article
Nature structural & molecular biology, ISSN 1545-9985, 2014, Volume 21, Issue 7, pp. 617 - 625
Nucleosomes are the fundamental unit of chromatin, but analysis of transcription-independent nucleosome functions has been complicated by the gene-expression... 
MITOSIS | XENOPUS EGG EXTRACTS | DNA INTERACTIONS | BIOPHYSICS | MITOTIC CHROMOSOME | KINASE AURORA-B | BIOCHEMISTRY & MOLECULAR BIOLOGY | RAN GTPASE | ENVELOPE | AUTOINTEGRATION FACTOR BAF | CHROMOSOMAL PASSENGER COMPLEX | CELL BIOLOGY | Guanine Nucleotide Exchange Factors - physiology | Xenopus Proteins - genetics | DNA-Binding Proteins - metabolism | Spindle Apparatus - metabolism | Guanine Nucleotide Exchange Factors - metabolism | Cell Cycle Proteins - genetics | Nuclear Proteins - genetics | DNA-Binding Proteins - physiology | Guanine Nucleotide Exchange Factors - genetics | Transcription Factors - physiology | Xenopus laevis | Cell Cycle Proteins - metabolism | Chromatin Assembly and Disassembly | Nucleosomes - metabolism | Nuclear Proteins - metabolism | Nucleosomes - physiology | DNA - metabolism | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Nuclear Pore - metabolism | Transcription Factors - metabolism | Nuclear Envelope - metabolism | Animals | Proteomics | Xenopus Proteins - physiology | Xenopus Proteins - metabolism | Models, Genetic | Nuclear Proteins - physiology | Histones - metabolism | Cell Cycle Proteins - physiology | Chromatin | DNA replication | DNA damage | Physiological aspects | Genetic aspects | Research | Amphibians | Gene expression | Molecular biology | Deoxyribonucleic acid--DNA
Journal Article
Cancer cell, ISSN 1535-6108, 2011, Volume 19, Issue 1, pp. 17 - 30
IDH1 and IDH2 mutations occur frequently in gliomas and acute myeloid leukemia, leading to simultaneous loss and gain of activities in the production of... 
BREAST-CANCER | TRANSCRIPTIONAL ACTIVITY | IDH2 MUTATIONS | ONCOLOGY | PROLYL HYDROXYLATION | INTEGRATED GENOMIC ANALYSIS | 2-OXOGLUTARATE OXYGENASES | ACUTE MYELOID-LEUKEMIA | HIF-ALPHA | HISTONE DEMETHYLATION | FAMILY | CELL BIOLOGY | Dioxygenases - metabolism | Histone Demethylases - antagonists & inhibitors | Gene Expression - genetics | Caenorhabditis elegans Proteins - chemistry | Humans | Ketoglutaric Acids - chemistry | Glioma - genetics | F-Box Proteins | Oxidoreductases, N-Demethylating - antagonists & inhibitors | Ketoglutaric Acids - pharmacology | Cytosine - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Glutarates - chemistry | Oxidoreductases, N-Demethylating - metabolism | DNA-Binding Proteins - antagonists & inhibitors | Glioma - enzymology | Endostatins - metabolism | Models, Molecular | Isocitrate Dehydrogenase - genetics | Histone Demethylases - metabolism | Dioxygenases - antagonists & inhibitors | Amino Acid Substitution - physiology | Procollagen-Proline Dioxygenase - genetics | Cell Line, Tumor | Isocitrate Dehydrogenase - metabolism | Glutarates - pharmacology | Histones - metabolism | Jumonji Domain-Containing Histone Demethylases - metabolism | Caenorhabditis elegans - enzymology | Cytosine - analogs & derivatives | Gene Expression - drug effects | Caenorhabditis elegans Proteins - metabolism | Isocitrate Dehydrogenase - antagonists & inhibitors | Glioma - metabolism | Procollagen-Proline Dioxygenase - metabolism | DNA-Binding Proteins - metabolism | Mixed Function Oxygenases | Biocatalysis - drug effects | Jumonji Domain-Containing Histone Demethylases - antagonists & inhibitors | Jumonji Domain-Containing Histone Demethylases - chemistry | Procollagen-Proline Dioxygenase - antagonists & inhibitors | Ketoglutaric Acids - metabolism | Oxalates - pharmacology | Binding, Competitive | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Catalytic Domain | Proto-Oncogene Proteins - genetics | Hypoxia-Inducible Factor-Proline Dioxygenases | DNA-Binding Proteins - genetics | Homeodomain Proteins - genetics | Animals | 5-Methylcytosine - metabolism | Caenorhabditis elegans Proteins - antagonists & inhibitors | Glutarates - metabolism
Journal Article
by Wang, Q and Zhang, Y and Yang, C and Xiong, H and Lin, Y and Yao, J and Li, H and Xie, L and Zhao, W and Yao, Y and Ning, Z.-B and Zeng, R and Xiong, Y and Guan, K.-L and Zhao, S and Zhao, G.-P
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2010, Volume 327, Issue 5968, pp. 1004 - 1007
Journal Article
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2012, Volume 339, Issue 6116, pp. 222 - 226
Journal Article
Cell metabolism, ISSN 1550-4131, 2012, Volume 15, Issue 6, pp. 838 - 847
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2010, Volume 331, Issue 6013, pp. 76 - 79
Vernalization is an environmentally-induced epigenetic switch in which winter cold triggers epigenetic silencing of floral repressors and thus provides... 
Chromatin | Cold regions | RNA | Reverse transcriptase polymerase chain reaction | Vernalization | REPORTS | Epigenetics | Genetic loci | Promoter regions | Repression | Plants | ARABIDOPSIS-THALIANA | COMPLEX | X-CHROMOSOME | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | GENES | REQUIRES | FLC | POLYCOMB | Chromatin - metabolism | Arabidopsis - physiology | RNA, Untranslated - metabolism | Arabidopsis - growth & development | Genes, Plant | Epigenesis, Genetic | Homeodomain Proteins - metabolism | RNA Polymerase II - metabolism | RNA, Plant - metabolism | RNA, Untranslated - genetics | Arabidopsis Proteins - metabolism | DNA-Binding Proteins - metabolism | RNA Interference | Plants, Genetically Modified | Gene Expression Regulation, Plant | Transcription, Genetic | Repressor Proteins - metabolism | Recombinant Proteins - metabolism | Promoter Regions, Genetic | Arabidopsis Proteins - genetics | Cold Temperature | Response Elements | Introns | MADS Domain Proteins - genetics | Gene Silencing | Nuclear Proteins - metabolism | Polycomb-Group Proteins | RNA, Plant - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Flowers - growth & development | Arabidopsis - genetics | MADS Domain Proteins - metabolism | Transcription Factors - metabolism | Carrier Proteins - metabolism | RNA, Antisense - metabolism | Histones - metabolism | RNA, Antisense - genetics | Epigenetic inheritance | Genetic aspects | Research | Plant biology | Plant reproduction | Flowers & plants | Gene expression
Journal Article
Nature (London), ISSN 1476-4687, 2013, Volume 505, Issue 7484, pp. 564 - 568
Journal Article