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1. Full Text PD-L1 expression is characteristic of a subset of aggressive B-cell lymphomas and virus-associated malignancies
by Chen, Benjamin J and Chapuy, Bjoern and Ouyang, Jing and Sun, Heather H and Roemer, Margaretha G. M and Xu, Mina L and Yu, Hongbo and Fletcher, Christopher D. M and Freeman, Gordon J and Shipp, Margaret A and Rodig, Scott J
Clinical Cancer Research, ISSN 1078-0432, 07/2013, Volume 19, Issue 13, pp. 3462 - 3473
Purpose: Programmed cell death ligand 1 (PD-L1) is an immunomodulatory molecule expressed by antigen-presenting cells and select tumors that engages receptors... 
DISTINCT ENTITY | IMMUNITY | ONCOLOGY | POSTTRANSPLANT LYMPHOPROLIFERATIVE DISORDERS | PROTEIN EXPRESSION | EBV | TUMOR-ASSOCIATED MACROPHAGES | B7-H1 | CLASSICAL HODGKIN LYMPHOMA | EPSTEIN-BARR-VIRUS | STERNBERG CELLS | Hodgkin Disease - virology | Immunohistochemistry | Gene Expression | Lymphoma, B-Cell - metabolism | Hodgkin Disease - metabolism | Hodgkin Disease - genetics | Humans | Lymphoma - immunology | Lymphoma - genetics | Lymphoma, B-Cell - genetics | B7-H1 Antigen - genetics | Lymphoma - metabolism | B7-H1 Antigen - metabolism | Herpesvirus 8, Human - pathogenicity | Lymphoma, B-Cell - immunology | Hodgkin Disease - immunology | Lymphoma, B-Cell - virology | Herpesvirus 4, Human - pathogenicity | Lymphoma - virology
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2. Full Text Cancer risk in people infected with human immunodeficiency virus in the United States
by Engels, Eric A and Biggar, Robert J and Hall, H. Irene and Cross, Helene and Crutchfield, Allison and Finch, Jack L and Grigg, Rebecca and Hylton, Tara and Pawlish, Karen S and McNeel, Timothy S and Goedert, James J
International Journal of Cancer, ISSN 0020-7136, 07/2008, Volume 123, Issue 1, pp. 187 - 194
Data are limited regarding cancer risk in human immunodeficiency virus (HIV)‐infected persons with modest immunosuppression, before the onset of acquired... 
HIV/AIDS | lung cancer | epidemiology | Kaposi sarcoma | non‐Hodgkin lymphoma | liver cancer | Hodgkin lymphoma | Non-Hodgkin lymphoma | Liver cancer | Lung cancer | Epidemiology | SQUAMOUS INTRAEPITHELIAL LESIONS | non-Hodgkin lymphoma | HUMAN-PAPILLOMAVIRUS | HODGKIN-LYMPHOMA | PREVALENCE | LUNG-CANCER | HEPATOCELLULAR-CARCINOMA | HIV-INFECTION | ONCOLOGY | ACTIVE ANTIRETROVIRAL THERAPY | COHORT | AIDS-DEFINING CANCERS | Hodgkin Disease - virology | Follow-Up Studies | HIV Infections - epidemiology | Humans | Middle Aged | Uterine Cervical Neoplasms - epidemiology | Child, Preschool | Infant | Male | Incidence | HIV Infections - immunology | Liver Neoplasms - epidemiology | Neoplasms - virology | Neoplasms - ethnology | Adult | Female | HIV Infections - transmission | Registries | Medical Record Linkage | Child | Colorado - epidemiology | Sarcoma, Kaposi - epidemiology | Infant, Newborn | Liver Neoplasms - virology | New Jersey - epidemiology | Florida - epidemiology | Lymphoma, Non-Hodgkin - virology | CD4 Lymphocyte Count | Hodgkin Disease - epidemiology | Sarcoma, Kaposi - virology | Lung Neoplasms - virology | Lymphoma, Non-Hodgkin - epidemiology | Antiretroviral Therapy, Highly Active | Lung Neoplasms - epidemiology | Adolescent | HIV Infections - complications | Uterine Cervical Neoplasms - virology | HIV Infections - drug therapy | Poisson Distribution | HIV Infections - ethnology | Neoplasms - epidemiology
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3. Full Text EBV positive mucocutaneous ulcer-A study of 26 cases associated with various sources of immunosuppression
by Dojcinov, Stefan D and Venkataraman, Girish and Raffeld, Mark and Pittaluga, Stefania and Jaffe, Elaine S
American Journal of Surgical Pathology, ISSN 0147-5185, 03/2010, Volume 34, Issue 3, pp. 405 - 417
We describe a series of Epstein Barr virus (EBV)-positive circumscribed, ulcerative lesions associated with various types of immunosuppression (IS). The study... 
Immunosuppression | Lymphoprolifeative | Epstein Barr virus | Mucocutaneous | SURGERY | CELL LYMPHOPROLIFERATIVE DISORDERS | OPTIMAL PRIMER SELECTION | NON-HODGKINS-LYMPHOMAS | immunosuppression | lymphoproliferative | PERIPHERAL-BLOOD | PATHOLOGY | CD8(+) T-CELLS | LYMPHOCYTE SUBPOPULATIONS | mucocutaneous | CYTOMEGALOVIRUS SEROPOSITIVITY | CHAIN-REACTION ANALYSIS | ELDERLY-PATIENTS | EPSTEIN-BARR-VIRUS | Immunohistochemistry | Recurrence | Humans | Middle Aged | Lymphoproliferative Disorders - chemically induced | Male | Skin Ulcer - immunology | Gastrointestinal Diseases - virology | T-Lymphocytes - virology | Epstein-Barr Virus Infections - etiology | Epstein-Barr Virus Infections - therapy | T-Lymphocytes - drug effects | Aged, 80 and over | B-Lymphocytes - virology | Gastrointestinal Diseases - pathology | Skin Diseases, Infectious - virology | Skin Diseases, Infectious - pathology | Mouth Mucosa - immunology | Immune Tolerance | Gastrointestinal Diseases - therapy | Lymphoproliferative Disorders - pathology | Epstein-Barr Virus Infections - pathology | B-Lymphocytes - immunology | Mouth Mucosa - virology | Remission, Spontaneous | T-Lymphocytes - immunology | Oral Ulcer - pathology | Skin Diseases, Infectious - immunology | Age Factors | Oral Ulcer - immunology | Lymphoproliferative Disorders - immunology | Lymphoproliferative Disorders - therapy | Oral Ulcer - chemically induced | Mouth Mucosa - drug effects | In Situ Hybridization | Epstein-Barr Virus Infections - chemically induced | Polymerase Chain Reaction | Adult | Female | Skin Ulcer - virology | Skin Diseases, Infectious - therapy | Gastrointestinal Diseases - immunology | Skin Ulcer - therapy | Epstein-Barr Virus Infections - immunology | Gene Rearrangement, T-Lymphocyte | Lymphoproliferative Disorders - virology | Skin Diseases, Infectious - chemically induced | Treatment Outcome | Skin Ulcer - chemically induced | Genes, Immunoglobulin | B-Lymphocytes - drug effects | Oral Ulcer - therapy | Skin Ulcer - pathology | Immunosuppressive Agents - adverse effects | Aged | Oral Ulcer - virology | Gastrointestinal Diseases - chemically induced | Muco-cutaneous | Lymphoproliferative
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4. Full Text Spectrum of Epstein-Barr virus-associated diseases
by Kutok, J.L and Wang, F
Annual Review of Pathology, ISSN 0066-4286, 2006, Volume 1, Issue 1, pp. 375 - 404
The association between Epstein-Barr virus (EBV) and a large number of benign and malignant diseases is unique among DNA viruses. Within infected tissues,... 
B lymphocyte | Latent infection | Gamma herpesvirus | Infectious mononucleosis | Burkitt lymphoma | REED-STERNBERG CELLS | NON-HODGKINS-LYMPHOMAS | KAPPA-B-ALPHA | ACUTE INFECTIOUS-MONONUCLEOSIS | latent infection | DENDRITIC CELL TUMOR | EBV NUCLEAR ANTIGEN-2 | gamma herpesvirus | POSTTRANSPLANTATION LYMPHOPROLIFERATIVE DISORDERS | NASOPHARYNGEAL CARCINOMA | LYMPHOEPITHELIOMA-LIKE CARCINOMA | LATENT MEMBRANE-PROTEIN | infectious mononucleosis | Hodgkin Disease - virology | Burkitt Lymphoma - virology | Hodgkin Disease - pathology | Infectious Mononucleosis - pathology | Virus Latency | Herpesvirus 4, Human - physiology | Humans | Epstein-Barr Virus Infections - pathology | Burkitt Lymphoma - pathology | Animals | Infectious Mononucleosis - virology | Virus Replication | B-Lymphocytes - virology | Epstein-Barr Virus Infections - complications | B-Lymphocytes - pathology | Cell Transformation, Viral
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5. Full Text The biology of Hodgkin's lymphoma
by Küppers, Ralf
Nature Reviews Cancer, ISSN 1474-175X, 01/2009, Volume 9, Issue 1, pp. 15 - 27
Hodgkin's lymphoma was first described in 1832. The aetiology of this lymphoma, however, remained enigmatic for along time. Only within the past 10 years has... 
REED-STERNBERG CELLS | CENTER B-CELLS | RECEPTOR TYROSINE KINASES | ONCOLOGY | REGULATORY T-CELLS | ANAPLASTIC LARGE-CELL | PERIPHERAL-BLOOD LYMPHOCYTES | COMPARATIVE GENOMIC HYBRIDIZATION | NF-KAPPA-B | EPSTEIN-BARR-VIRUS | FUNCTIONAL CD30 LIGAND | Hodgkin Disease - virology | Transcription Factors - physiology | Tumor Escape | Signal Transduction | Hodgkin Disease - genetics | Hodgkin Disease - pathology | Humans | Neoplasm Proteins - physiology | Gene Expression Regulation, Neoplastic | Inflammation | Germinal Center - pathology | Epstein-Barr Virus Infections - pathology | Intercellular Signaling Peptides and Proteins - physiology | Hodgkin Disease - etiology | Reed-Sternberg Cells - pathology | Viral Proteins - physiology | B-Lymphocytes - virology | Hodgkin Disease - immunology | Herpesvirus 4, Human - pathogenicity | B-Lymphocytes - pathology | Neoplasm Proteins - genetics | Cell Dedifferentiation - genetics | Cell Transformation, Viral | Development and progression | Care and treatment | Research | Health aspects | Hodgkin's disease | Cancer
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6. Full Text Persistence of the Epstein–Barr Virus and the Origins of Associated Lymphomas
by Thorley-Lawson, David A and Gross, Andrew
The New England Journal of Medicine, ISSN 0028-4793, 03/2004, Volume 350, Issue 13, pp. 1328 - 1337
This review of the life cycle of the Epstein–Barr virus (EBV) explains how EBV establishes lifelong infection in a host with protective immunity against the... 
Hodgkin Disease - virology | B-Lymphocytes - immunology | Herpesvirus 4, Human - physiology | Humans | Herpesvirus 4, Human - immunology | B-Lymphocytes - virology | Epstein-Barr Virus Infections - complications | T-Lymphocytes - immunology | Herpesvirus 4, Human - pathogenicity | Immunocompromised Host | Lymphoma - virology | Pathology | Lymphomas | Microbiology | Herpes viruses
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7. Full Text Epstein-Barr virus and oncogenesis: from latent genes to tumours
by Young, Lawrence S and Murray, Paul G
Oncogene, ISSN 0950-9232, 08/2003, Volume 22, Issue 33, pp. 5108 - 5121
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus associated with the development of both lymphoid and epithelial tumours. As a common virus... 
Epstein-Barr virus | Carcinoma | Latent genes | Lymphoma | latent genes | REED-STERNBERG CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | lymphoma | HERPES-TYPE VIRUS | CELL BIOLOGY | NASOPHARYNGEAL CARCINOMA | ONCOLOGY | carcinoma | ENCODED NUCLEAR ANTIGEN | MEMBRANE-PROTEIN 1 | GENETICS & HEREDITY | LYMPHOEPITHELIOMA-LIKE CARCINOMA | BURKITT-LYMPHOMA CELLS | RECEPTOR-ASSOCIATED FACTOR-1 | CLASSICAL HODGKINS-DISEASE | NF-KAPPA-B | Hodgkin Disease - virology | Genome, Viral | Neoplasms - virology | Herpesvirus 4, Human - genetics | Burkitt Lymphoma - virology | Stomach Neoplasms - virology | Humans | Nasopharyngeal Neoplasms - virology | Lymphoma, T-Cell - virology | Models, Genetic | Cell Line, Transformed
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8. Full Text Epstein-Barr virus–associated lymphoproliferative disorders
by Rezk, Sherif A., MD and Weiss, Lawrence M., MD
Human Pathology, ISSN 0046-8177, 2007, Volume 38, Issue 9, pp. 1293 - 1304
Summary Epstein-Barr virus (EBV) is a member of the human herpesvirus family that was initially isolated from a cultured Burkitt lymphoma cell line by Epstein... 
Pathology | T-cell lymphoproliferative disorders | HIV-associated lymphoproliferative disorders | Epstein-Barr virus | B-cell lymphoproliferative disorders | epstein-Barr virus | PRIMARY EFFUSION LYMPHOMA | NON-HODGKINS-LYMPHOMAS | LYMPHADENOPATHY-LIKE LYMPHOMA | T-CELL LYMPHOMA | PATHOLOGY | disorders | POLYMERASE-CHAIN-REACTION | T-cell lymphoproliferative | HIV-POSITIVE PATIENTS | AIDS-RELATED LYMPHOMAS | CENTRAL-NERVOUS-SYSTEM | ANGIOCENTRIC IMMUNOPROLIFERATIVE LESIONS | B-cell lymphoproliferative | REED-STERNBERG-CELLS | Hodgkin Disease - virology | Burkitt Lymphoma - virology | Killer Cells, Natural - virology | Epstein-Barr Virus Infections - immunology | Humans | Lymphoproliferative Disorders - virology | Lymphomatoid Granulomatosis - virology | Lymphoproliferative Disorders - immunology | Herpesvirus 4, Human - isolation & purification | Immunosuppression | B-Lymphocytes - immunology | HIV Infections - complications | B-Lymphocytes - virology | Killer Cells, Natural - immunology | Epstein-Barr Virus Infections - complications | Lymphoma - virology | Lymphomas | Proteins | Viruses | Tumors | Immune system
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9. Full Text Epstein–Barr virus in autoimmune diseases
by Toussirot, Éric, MD, PhD and Roudier, Jean, MD, PhD
Best Practice & Research: Clinical Rheumatology, ISSN 1521-6942, 2008, Volume 22, Issue 5, pp. 883 - 896
Autoimmune diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and primary Sjögren's syndrome (pSS) are complex disorders with a... 
Rheumatology | autoimmune diseases | molecular mimicry | Epstein–Barr virus | Epstein-Barr virus | RHEUMATOID-ARTHRITIS | SYSTEMIC-LUPUS-ERYTHEMATOSUS | MALIGNANT-LYMPHOMA | SJOGRENS-SYNDROME | SALIVARY-GLAND BIOPSIES | RHEUMATOLOGY | POLYMERASE-CHAIN-REACTION | HUMORAL AUTOIMMUNITY | NON-HODGKINS-LYMPHOMA | GLYCOPROTEIN GP110 | Autoimmune Diseases - physiopathology | Epstein-Barr Virus Infections - physiopathology | Herpesvirus 4, Human - genetics | Humans | Lupus Erythematosus, Systemic - virology | Herpesvirus 4, Human - immunology | Sjogren's Syndrome - physiopathology | RNA, Viral - analysis | DNA, Viral - analysis | Autoimmune Diseases - virology | Arthritis, Rheumatoid - virology | Sjogren's Syndrome - virology | Viral Load | Herpesvirus 4, Human - isolation & purification | Epstein-Barr Virus Infections - complications | Epstein-Barr Virus Infections - blood | Lupus Erythematosus, Systemic - physiopathology | Arthritis, Rheumatoid - physiopathology | Lymphoma - virology | Lupus | Virus diseases | Rheumatoid factor | Systemic lupus erythematosus | Health aspects | Rheumatoid arthritis | Sjogren's Syndrome | Lymphoma | Arthritis, Rheumatoid | Herpesvirus 4, Human | Virology | Life Sciences | Microbiology and Parasitology | Autoimmune Diseases | Lupus Erythematosus, Systemic | RNA, Viral | Epstein-Barr Virus Infections | DNA, Viral
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