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Developmental Cell, ISSN 1534-5807, 03/2012, Volume 22, Issue 3, pp. 501 - 514
Gradients of vascular endothelial growth factor (VEGF) induce single endothelial cells to become leading tip cells of emerging angiogenic sprouts. Tip cells... 
DEFECTS | TIP CELLS | ANGIOGENESIS | VEGF | ENDOTHELIAL-CELLS | ID PROTEINS | HES1 | DEVELOPMENTAL BIOLOGY | DIFFERENTIATION | EXPRESSION | INHIBITS TUMOR-GROWTH | CELL BIOLOGY | Transcription Factor HES-1 | Humans | Intercellular Signaling Peptides and Proteins - biosynthesis | Intracellular Signaling Peptides and Proteins - metabolism | Inhibitor of Differentiation Proteins - biosynthesis | Inhibitor of Differentiation Protein 1 - biosynthesis | Serrate-Jagged Proteins | Smad5 Protein - metabolism | Basic Helix-Loop-Helix Transcription Factors - biosynthesis | Smad1 Protein - genetics | Membrane Proteins - metabolism | Smad5 Protein - genetics | Intracellular Signaling Peptides and Proteins - genetics | Jagged-1 Protein | Calcium-Binding Proteins - biosynthesis | Homeodomain Proteins - biosynthesis | Signal Transduction | Inhibitor of Differentiation Protein 2 - biosynthesis | Membrane Proteins - genetics | Down-Regulation | Cells, Cultured | Mice, Transgenic | Cell Cycle Proteins - biosynthesis | Vascular Endothelial Growth Factor Receptor-1 - biosynthesis | Mice, Knockout | Membrane Proteins - biosynthesis | Phenotype | Animals | Smad1 Protein - metabolism | Mice | Neovascularization, Physiologic | Proteins | Endothelial growth factors | Genes | Genetic aspects | Transforming growth factors | Vascular endothelial growth factor | Endothelium | Index Medicus | Dll4 | tip cell | lateral inhibition | sprouting angiogenesis | BMP | directed migration | Notch | stalk cell | mouse embryo | Smad | polarity
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 2006, Volume 341, Issue 4, pp. 1135 - 1140
Mesenchymal stem cells (MSC) from mouse bone marrow were shown to adopt a pancreatic endocrine phenotype in vitro and to reverse diabetes in an animal model.... 
Human | Nestin | Adipose tissue | Glucagon | Isl-1 | Differentiation | Insulin | Mesenchymal stem cells | ABCG2 | PROGENITOR CELLS | VITRO | differentiation | TRANSPORTER | insulin | RAT | BIOCHEMISTRY & MOLECULAR BIOLOGY | nestin | ENDOCRINE | adipose tissue | BIOPHYSICS | HUMAN BONE-MARROW | mesenchymal stem cells | IN-VIVO | glucagon | PANCREATIC BETA-CELLS | STROMAL CELLS | human | BRAIN | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Glucagon - biosynthesis | Homeodomain Proteins - biosynthesis | Neoplasm Proteins - biosynthesis | Humans | Cells, Cultured | Adipose Tissue - cytology | Intermediate Filament Proteins - biosynthesis | Mesenchymal Stromal Cells - metabolism | Proto-Oncogene Proteins c-kit - biosynthesis | Insulin - biosynthesis | Somatostatin - biosynthesis | ATP-Binding Cassette Transporters - biosynthesis | Mesenchymal Stromal Cells - cytology | Stem Cell Factor - biosynthesis | Nerve Tissue Proteins - biosynthesis | Thy-1 Antigens - biosynthesis | LIM-Homeodomain Proteins | Cell Differentiation | Transcription Factors | Stem cell research | Analysis | Stem cells | Somatostatin | Diabetes | Hormones | Intermediate filament proteins | Index Medicus | TRANSCRIPTION FACTORS | PANCREAS | PHENOTYPE | BONE MARROW | CELL PROLIFERATION | 60 APPLIED LIFE SCIENCES | INSULIN | POLYMERASE CHAIN REACTION | IN VITRO | SOMATOSTATIN | MICE | STEM CELLS | ADIPOSE TISSUE | GLUCAGON
Journal Article
Prostate, ISSN 0270-4137, 2009, Volume 69, Issue 15, pp. 1683 - 1693
BACKGROUND: According to the cancer stem cell hypothesis, tumor growth is sustained by a subpopulation of cancer stem/progenitor-like cells. Self-renewal and... 
Cancer stem/progenitor-like cells | Self-renewal | PSCA | Prostaspheres | CD49f | PROGENITOR CELLS | POPULATION | PROSPECTIVE IDENTIFICATION | prostaspheres | self-renewal | TUMOR-INITIATING CELLS | MURINE | EPITHELIAL STEM-CELLS | ENDOCRINOLOGY & METABOLISM | UROLOGY & NEPHROLOGY | cancer stem/progenitor-like cells | DIFFERENTIATION | PROGRESSION | CD133 | Immunohistochemistry | Prostatic Neoplasms - metabolism | Nestin | Proto-Oncogene Proteins c-met - biosynthesis | Antigens, CD - biosynthesis | Humans | Membrane Glycoproteins - biosynthesis | GPI-Linked Proteins | Octamer Transcription Factor-3 - biosynthesis | Cell Growth Processes - physiology | Intercellular Signaling Peptides and Proteins - biosynthesis | Male | Gene Expression Profiling | Proto-Oncogene Proteins - biosynthesis | Antigens, CD - genetics | Octamer Transcription Factor-3 - genetics | RNA, Messenger - biosynthesis | Prostatic Neoplasms - genetics | Neoplastic Stem Cells - metabolism | Serrate-Jagged Proteins | Intermediate Filament Proteins - genetics | Nerve Tissue Proteins - biosynthesis | Neoplastic Stem Cells - pathology | Retrospective Studies | Neoplasm Proteins - genetics | Jagged-1 Protein | Prostatic Neoplasms - pathology | Antigens, Neoplasm | Calcium-Binding Proteins - biosynthesis | Homeodomain Proteins - biosynthesis | Nanog Homeobox Protein | Keratin-14 - biosynthesis | Membrane Proteins - genetics | Neoplasm Proteins - biosynthesis | RNA, Messenger - genetics | Intercellular Signaling Peptides and Proteins - genetics | Intermediate Filament Proteins - biosynthesis | Proto-Oncogene Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Keratin-14 - genetics | Nerve Tissue Proteins - genetics | Homeodomain Proteins - genetics | Membrane Glycoproteins - genetics | Proto-Oncogene Proteins c-met - genetics | Membrane Proteins - biosynthesis | Clone Cells - pathology | Calcium-Binding Proteins - genetics | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 07/2011, Volume 71, Issue 13, pp. 4640 - 4652
Journal Article
Journal Article
Cancer Science, ISSN 1347-9032, 01/2016, Volume 107, Issue 1, pp. 18 - 27
Numerous studies suggest that several long non‐coding RNA s (lnc RNA s) play critical roles in bladder cancer development and progression. Long non‐coding RNA... 
1 | UCA | RNA | Hsa‐miR‐145 | epithelial to mesenchymal transition | long non‐coding | Bladder cancer | Epithelial to mesenchymal transition | UCA1 | Hsa-miR-145 | Long non-coding RNA | METASTASIS | MIR-145 | TO-MESENCHYMAL TRANSITION | ONCOLOGY | PROSTATE-CANCER | TUMOR-SUPPRESSOR | long non-coding RNA | DIFFERENTIATION | CARCINOMA | CONTRIBUTES | ABERRANT EXPRESSION | Humans | Middle Aged | Male | Epithelial-Mesenchymal Transition - genetics | Zinc Finger E-box Binding Homeobox 2 | Urinary Bladder Neoplasms - genetics | Neoplasm Invasiveness - pathology | Polymerase Chain Reaction | Urinary Bladder Neoplasms - pathology | Female | Microfilament Proteins - genetics | Gene Expression Regulation, Neoplastic - genetics | Carcinoma, Transitional Cell - genetics | Homeodomain Proteins - biosynthesis | Carrier Proteins - biosynthesis | Repressor Proteins - genetics | MicroRNAs - biosynthesis | Transcription Factors - biosynthesis | RNA, Long Noncoding - genetics | Transcription Factors - genetics | Blotting, Western | Homeodomain Proteins - genetics | Carrier Proteins - genetics | Microfilament Proteins - biosynthesis | Repressor Proteins - biosynthesis | Carcinoma, Transitional Cell - pathology | Fluorescent Antibody Technique | Signal Transduction - physiology | Aged | MicroRNAs - genetics | Neoplasm Invasiveness - genetics | Zinc Finger E-box-Binding Homeobox 1 | Stem cells | Development and progression | Metastasis | Health savings accounts | Muscle proteins | Protein binding | Index Medicus | Original | long non‐coding RNA
Journal Article
Neuron, ISSN 0896-6273, 04/2008, Volume 58, Issue 1, pp. 52 - 64
Expression of the Notch effector gene is required for maintenance of neural progenitors in the embryonic brain, but persistent and high levels of expression... 
STEMCELL | DEVBIO | MOLNEURO | STEM-CELLS | MAMMALIAN HAIRY | DELTA-HOMOLOG | LOOP-HELIX FACTORS | NEGATIVE AUTOREGULATION | HES1 EXPRESSION | CENTRAL-NERVOUS-SYSTEM | SOMITE SEGMENTATION | PRESOMITIC MESODERM | NEUROSCIENCES | FEEDBACK LOOP | Transcription Factor HES-1 | Intercellular Signaling Peptides and Proteins - biosynthesis | Neurons - cytology | Receptors, Notch - genetics | Stem Cells - cytology | Intercellular Signaling Peptides and Proteins - physiology | Receptors, Notch - biosynthesis | Basic Helix-Loop-Helix Transcription Factors - biosynthesis | Nerve Tissue Proteins - biosynthesis | Neurons - physiology | Female | Cell Differentiation - physiology | Basic Helix-Loop-Helix Transcription Factors - physiology | Nerve Tissue Proteins - physiology | Basic Helix-Loop-Helix Transcription Factors - genetics | Homeodomain Proteins - biosynthesis | Cells, Cultured | Intercellular Signaling Peptides and Proteins - genetics | Receptors, Notch - physiology | Mice, Transgenic | Nerve Tissue Proteins - genetics | Homeodomain Proteins - genetics | Pregnancy | Animals | Biological Clocks - physiology | Signal Transduction - physiology | Stem Cells - physiology | Mice | Homeodomain Proteins - physiology | Heparan sulfate | Proteins | Signal transduction | Rodents | Cell division | Ligands | Protein expression | Genomes | Gene expression | Index Medicus
Journal Article
Biology of Reproduction, ISSN 0006-3363, 2007, Volume 77, Issue 3, pp. 577 - 588
Abstract The amnion is the inner of two membranes surrounding the fetus. That it arises from embryonic epiblast cells prior to gastrulation suggests that it... 
stem cells | placenta | fetal membranes | developmental biology | amnion | Amnion | Fetal membranes | Placenta | Developmental biology | Stem cells | HUMAN PLACENTA | MARKERS | AMNIOTIC EPITHELIAL-CELLS | CARDIOMYOCYTES | CULTURE | LINES | TRANSPLANTATION | REPRODUCTIVE BIOLOGY | cells | FLUID | GENE | EXPRESSION | stem | Immunohistochemistry | Fetal Stem Cells - cytology | Fetal Stem Cells - metabolism | Humans | Multipotent Stem Cells - metabolism | Octamer Transcription Factor-3 - biosynthesis | Male | Glycosphingolipids - genetics | HMGB Proteins - biosynthesis | Octamer Transcription Factor-3 - genetics | Stem Cell Transplantation | RNA, Messenger - biosynthesis | Flow Cytometry | HMGB Proteins - genetics | Female | Histocompatibility Antigens Class I - biosynthesis | SOXB1 Transcription Factors | Cell Differentiation - physiology | Homeodomain Proteins - biosynthesis | Nanog Homeobox Protein | Glycosphingolipids - biosynthesis | RNA, Messenger - genetics | Histocompatibility Antigens Class II - biosynthesis | Transcription Factors - biosynthesis | Histocompatibility Antigens Class I - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mice, SCID | Reverse Transcriptase Polymerase Chain Reaction | Amnion - physiology | Homeodomain Proteins - genetics | Animals | Multipotent Stem Cells - cytology | Mice | Histocompatibility Antigens Class II - genetics | DNA-Binding Proteins - biosynthesis | Stage-Specific Embryonic Antigens | Index Medicus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 03/2006, Volume 26, Issue 11, pp. 3066 - 3076
The deep cerebellar nuclei (DCN) are the main output centers of the cerebellum, but little is known about their development. Using transcription factors as... 
reeler | Tbr2 | Pax6 | Tbr1 | Fastigial nucleus | Brn2 | EXPRESSION DEFINES | EMBRYONIC-DEVELOPMENT | MURINE CEREBELLUM | BRAIN-DEVELOPMENT | NEUROSCIENCES | MUTANT MICE | RAT CEREBELLUM | VESICULAR GLUTAMATE TRANSPORTERS | fastigial nucleus | GABAERGIC INTERNEURONS | GRANULE CELLS | MOUSE CEREBELLUM | Paired Box Transcription Factors - biosynthesis | Paired Box Transcription Factors - genetics | Cerebellar Nuclei - embryology | Axonal Transport | Cerebellar Nuclei - cytology | Extracellular Matrix Proteins - biosynthesis | Efferent Pathways - physiology | Red Nucleus - embryology | T-Box Domain Proteins - biosynthesis | Efferent Pathways - embryology | Neurons - cytology | Mice, Neurologic Mutants | Morphogenesis | Rhombencephalon - cytology | Cerebellar Nuclei - abnormalities | Nerve Tissue Proteins - biosynthesis | Serine Endopeptidases - genetics | Neurons - metabolism | Eye Proteins - genetics | Rhombencephalon - embryology | Homeodomain Proteins - biosynthesis | Serine Endopeptidases - biosynthesis | Extracellular Matrix Proteins - genetics | Mice, Inbred C57BL | Glutamic Acid - physiology | Repressor Proteins - genetics | Transcription Factors - biosynthesis | PAX6 Transcription Factor | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Gestational Age | Nerve Tissue Proteins - genetics | T-Box Domain Proteins - genetics | Cell Adhesion Molecules, Neuronal - genetics | Homeodomain Proteins - genetics | Red Nucleus - cytology | Cell Lineage | Animals | Repressor Proteins - biosynthesis | Cell Adhesion Molecules, Neuronal - biosynthesis | Biomarkers | Rhombencephalon - metabolism | Mice | DNA-Binding Proteins - biosynthesis | Microscopy, Fluorescence | Cell Movement | Eye Proteins - biosynthesis | Index Medicus
Journal Article
Journal Article
Nature, ISSN 0028-0836, 08/2010, Volume 466, Issue 7307, pp. 765 - 768
Chronic myelogenous leukaemia (CML) can progress from a slow growing chronic phase to an aggressive blast crisis phase, but the molecular basis of this... 
CHRONIC MYELOGENOUS LEUKEMIA | MURINE MODEL | STEM-CELLS | TRANSLATIONAL REPRESSION | RNA | BINDING PROTEIN MUSASHI-1 | MULTIDISCIPLINARY SCIENCES | BCR-ABL | GENE-EXPRESSION | NUMB | CML BLAST CRISIS | RNA-Binding Proteins - genetics | Up-Regulation | Oncogene Proteins, Fusion - metabolism | Prognosis | Homeodomain Proteins - metabolism | Humans | Gene Expression Regulation, Neoplastic | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics | Nuclear Pore Complex Proteins - genetics | Cell Differentiation - genetics | RNA-Binding Proteins - biosynthesis | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | Nerve Tissue Proteins - biosynthesis | Membrane Proteins - metabolism | Blast Crisis - pathology | Signal Transduction | Membrane Proteins - genetics | Nuclear Pore Complex Proteins - metabolism | Mice, Inbred C57BL | Tumor Suppressor Protein p53 - metabolism | Receptor, Notch1 - metabolism | Nerve Tissue Proteins - genetics | Disease Progression | Homeodomain Proteins - genetics | Nerve Tissue Proteins - metabolism | Fusion Proteins, bcr-abl - genetics | Membrane Proteins - biosynthesis | Animals | Oncogene Proteins, Fusion - genetics | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - metabolism | Blast Crisis - genetics | Mice | Blast Crisis - metabolism | Fusion Proteins, bcr-abl - metabolism | RNA-Binding Proteins - metabolism | Myelocytic leukemia | Molecular genetics | Physiological aspects | Development and progression | Nonlymphoid leukemia | Cellular signal transduction | Genetic aspects | Research | Genetic regulation | Gene expression | Medical research | Stem cells | Chronic illnesses | Index Medicus
Journal Article