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Nature Immunology, ISSN 1529-2908, 05/2012, Volume 13, Issue 5, pp. 499 - 510
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2013, Volume 110, Issue 32, pp. 13097 - 13102
Skin homeostasis is critical to preserve animal integrity. Although the skin of most vertebrates is known to contain a skin-associated lymphoid tissue (SALT),... 
Immunoglobulins | Microbiota | B lymphocytes | Antibodies | Bacteria | Skin | Mucus | Infections | Parasites | Mammals | Evolution | Ichthyophthirius multifiliis | Cutaneous | Mucosal immunoglobulin | cutaneous | COLLECTION | IGA | RAINBOW-TROUT | DENDRITIC CELLS | MULTIDISCIPLINARY SCIENCES | mucosal immunoglobulin | evolution | IDENTIFICATION | DERMATOLOGY | B-CELLS | IMMUNOGLOBULIN-A | LYMPHOID-TISSUE | FISH | Immunity, Mucosal - immunology | Skin - microbiology | Immunoglobulins - immunology | Mucous Membrane - parasitology | Immunoglobulin M - immunology | Fish Diseases - parasitology | Host-Pathogen Interactions - immunology | Lymphoid Tissue - immunology | Hymenostomatida - immunology | Epidermis - parasitology | Gastrointestinal Tract - immunology | Bacteria - immunology | Flow Cytometry | Oncorhynchus mykiss - microbiology | Epidermis - microbiology | Immunoglobulins - blood | Fish Diseases - immunology | B-Lymphocyte Subsets - immunology | Oncorhynchus mykiss - immunology | Oncorhynchus mykiss - parasitology | Skin - immunology | Fish Diseases - microbiology | Skin - parasitology | Host-Parasite Interactions - immunology | Blotting, Western | Animals | B-Lymphocytes - immunology | Immunoglobulin M - blood | Epidermis - immunology | Mucous Membrane - immunology | Hymenostomatida - physiology | Microscopy, Fluorescence | Mucous Membrane - microbiology | Physiological aspects | Homeostasis | Immune response | Research | Teleostei | Tissue | Vertebrates | Fish | Immune system | Index Medicus | Biological Sciences
Journal Article
Immunity, ISSN 1074-7613, 03/2013, Volume 38, Issue 3, pp. 514 - 527
Interleukin-21 (IL-21) has broad actions on T and B cells, but its actions in innate immunity are poorly understood. Here we show that IL-21 induced apoptosis... 
NKT CELLS | HOMEOSTASIS | FOLLICULAR-HELPER-CELLS | HUMAN B-CELLS | STEADY-STATE | INTERLEUKIN-21 | DIFFERENTIATION | IMMUNOLOGY | IMMUNE TOLERANCE | T-CELLS | NEGATIVE REGULATOR | Natural Killer T-Cells - drug effects | Oligonucleotide Array Sequence Analysis | Apoptosis - drug effects | Dendritic Cells - immunology | STAT5 Transcription Factor - immunology | Receptors, Interleukin-21 - genetics | Interferon-gamma - metabolism | CD4-Positive T-Lymphocytes - immunology | Interleukins - genetics | Gene Expression - immunology | STAT3 Transcription Factor - genetics | Apoptosis Regulatory Proteins - immunology | DNA-Binding Proteins - immunology | Membrane Proteins - genetics | CD4-Positive T-Lymphocytes - metabolism | Mice, Transgenic | DNA, Intergenic - genetics | Protein Binding - immunology | Blotting, Western | Apoptosis Regulatory Proteins - metabolism | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Mice, Knockout | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Galactosylceramides - immunology | Mice | STAT3 Transcription Factor - immunology | Gene Expression - drug effects | Galactosylceramides - pharmacology | DNA-Binding Proteins - deficiency | STAT5 Transcription Factor - genetics | STAT5 Transcription Factor - metabolism | Receptors, Interleukin-21 - deficiency | Flow Cytometry | Bcl-2-Like Protein 11 | Natural Killer T-Cells - metabolism | DNA, Intergenic - metabolism | Interleukins - immunology | Proto-Oncogene Proteins - immunology | Apoptosis Regulatory Proteins - genetics | Dendritic Cells - drug effects | Membrane Proteins - metabolism | Interleukins - pharmacology | Dendritic Cells - metabolism | STAT3 Transcription Factor - metabolism | Proto-Oncogene Proteins - metabolism | Receptors, Interleukin-21 - immunology | Mice, Inbred C57BL | Cells, Cultured | Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology | Membrane Proteins - immunology | Proto-Oncogene Proteins - genetics | DNA-Binding Proteins - genetics | Animals | Apoptosis - immunology | Interferon-gamma - immunology | CD4-Positive T-Lymphocytes - drug effects | DNA, Intergenic - immunology | Natural Killer T-Cells - immunology | Interleukins | Dendritic cells | Analysis | Genomics | Macrophage colony stimulating factor | Biological response modifiers | T cells | Apoptosis | Cytokines | Genes | Genomes | Kinases | Binding sites | Deoxyribonucleic acid--DNA | Index Medicus | apoptosis | dendritic cells | GM-CSF | IL-21
Journal Article
Immunity, ISSN 1074-7613, 04/2015, Volume 42, Issue 4, pp. 665 - 678
Journal Article
Journal of Immunology, ISSN 0022-1767, 02/2014, Volume 192, Issue 3, pp. 919 - 928
The Lyn tyrosine kinase regulates inhibitory signaling in B and myeloid cells: loss of Lyn results in a lupus-like autoimmune disease with hyperactive B cells... 
SYSTEMIC-LUPUS-ERYTHEMATOSUS | ACTIVATION | PROTEIN | DENDRITIC CELLS | DISEASE | GERMINAL CENTER | DEFICIENT MICE | IMMUNOLOGY | MATURATION | AUTOANTIBODY PRODUCTION | T-CELLS | T-Lymphocyte Subsets - immunology | Antibody Specificity | Antibodies, Antinuclear - biosynthesis | Myeloproliferative Disorders - enzymology | Immune Complex Diseases - immunology | Spleen - immunology | Kidney - pathology | Antibodies, Antinuclear - immunology | Cell Count | Germinal Center - immunology | Kidney - immunology | Homeostasis | Myeloproliferative Disorders - immunology | Immunoglobulin M - immunology | Myeloproliferative Disorders - genetics | src-Family Kinases - deficiency | Lupus Nephritis - etiology | Immunoglobulin G - biosynthesis | Autoimmunity - immunology | Immunoglobulin G - immunology | Myeloid Differentiation Factor 88 - immunology | Calcium Signaling - immunology | Spleen - pathology | Immunoglobulin Class Switching | Disease Models, Animal | B-Lymphocytes - enzymology | Lymphocyte Activation | Mice, Inbred C57BL | Mice, Transgenic | Lupus Nephritis - immunology | Germinal Center - pathology | Organ Specificity | src-Family Kinases - immunology | Immune Complex Diseases - pathology | Antibodies, Antinuclear - genetics | Lupus Nephritis - enzymology | Animals | B-Lymphocytes - immunology | Myeloid Differentiation Factor 88 - deficiency | Lymphopoiesis - immunology | Mice | src-Family Kinases - genetics | Immunoglobulin M - biosynthesis | Plasma Cells - immunology | Index Medicus | Abridged Index Medicus
Journal Article
Immunity, ISSN 1074-7613, 09/2015, Volume 43, Issue 3, pp. 566 - 578
Three subsets of invariant natural killer T (iNKT) cells have been identified, NKT1, NKT2, and NKT17, which produce distinct cytokines when stimulated, but... 
ACTIVATION | HOMEOSTASIS | ALPHA-GALACTOSYLCERAMIDE | INVARIANT NKT CELLS | KILLER T-CELLS | ORPHAN RECEPTOR | IMMUNOLOGY | IDENTIFICATION | EXPRESSION | PROGRAM | CUTTING EDGE | Organ Specificity - drug effects | T-Lymphocyte Subsets - immunology | Spleen - immunology | T-Lymphocyte Subsets - cytology | Thymocytes - metabolism | Interferon-gamma - metabolism | Galactosylceramides - pharmacology | Lung - cytology | Organ Specificity - immunology | Liver - immunology | Lymphocyte Activation - immunology | Flow Cytometry | Natural Killer T-Cells - metabolism | Lung - metabolism | Thymus Gland - metabolism | Cytokines - immunology | Cytokines - metabolism | Interleukin-4 - metabolism | Liver - metabolism | Mice, Inbred C57BL | Cells, Cultured | Thymus Gland - cytology | Lymph Nodes - metabolism | Mice, Transgenic | Spleen - cytology | Lymph Nodes - immunology | Lymph Nodes - cytology | Natural Killer T-Cells - classification | Mice, Knockout | Thymocytes - immunology | Interleukin-4 - immunology | Animals | Galactosylceramides - immunology | Spleen - metabolism | Lymphocyte Activation - drug effects | T-Lymphocyte Subsets - metabolism | Interferon-gamma - immunology | Fluorescent Antibody Technique | Mice, Inbred NOD | Thymus Gland - immunology | Liver - cytology | Mice, Inbred BALB C | Lung - immunology | Natural Killer T-Cells - immunology | Cytokines | Biological response modifiers | T cells | Studies | Flow cytometry | Transcription factors | Statistical analysis | Lymphocytes | Rodents | Lipids | T cell receptors | Software | Experiments | Index Medicus
Journal Article
by Wang, J and Li, FQ and Wei, HM and Lian, ZX and Sun, R and Tian, ZG
JOURNAL OF EXPERIMENTAL MEDICINE, ISSN 0022-1007, 11/2014, Volume 211, Issue 12, pp. 2397 - 2410
Influenza in humans is often accompanied by gastroenteritis-like symptoms such as diarrhea, but the underlying mechanism is not yet understood. We explored the... 
MEDICINE, RESEARCH & EXPERIMENTAL | TRACT | HOMEOSTASIS | MUCOSAL IMMUNOLOGICAL SYSTEM | RECOGNITION | GUT | ESCHERICHIA-COLI INFECTION | IMMUNOLOGY | EXPRESSION | T-CELLS | BOWEL-DISEASE | LYMPHOCYTES | Influenza A Virus, H1N1 Subtype - immunology | Intestines - drug effects | Lung - microbiology | Epithelial Cells - metabolism | Receptors, CCR - metabolism | Humans | Influenza A Virus, H1N1 Subtype - physiology | Interleukin-17 - immunology | Male | Interleukin-15 - immunology | Intestines - immunology | Host-Pathogen Interactions - immunology | Orthomyxoviridae Infections - genetics | CD4-Positive T-Lymphocytes - immunology | Antibodies, Neutralizing - immunology | Flow Cytometry | Th17 Cells - metabolism | Chemokines, CC - immunology | Microbiota - immunology | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Interleukin-17 - genetics | Antibodies, Neutralizing - pharmacology | Inflammation - immunology | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Interleukin-17 - metabolism | Animals | Intestines - microbiology | Receptors, CCR - immunology | Epithelial Cells - immunology | Interleukin-15 - metabolism | Inflammation - genetics | Th17 Cells - immunology | Orthomyxoviridae Infections - virology | Lung - immunology | Orthomyxoviridae Infections - immunology | Chemokines, CC - metabolism | Index Medicus | 305
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 136, Issue 2, pp. 413 - 422
Background Thymic stromal lymphopoietin (TSLP) is a cytokine with pleiotropic functions in the immune system. It has been associated with allergic reactions in... 
Allergy and Immunology | Thymic stromal lymphopoietin | gut homeostasis | celiac disease | anti-inflammatory drugs | atopic dermatitis | ulcerative colitis | skin homeostasis | DENDRITIC CELLS | TSLP | INDUCE | RECEPTOR | IMMUNOLOGY | ATOPIC-DERMATITIS | POLYMORPHISMS | EPITHELIAL-CELLS | ALLERGY | ASTHMA | NF-KAPPA-B | EXPRESSION | Dermatitis, Atopic - genetics | Skin - microbiology | Dendritic Cells - immunology | Humans | Salmonella Infections - genetics | Colitis, Ulcerative - genetics | Salmonella Infections - immunology | Dendritic Cells - pathology | Dermatitis, Atopic - microbiology | Colitis, Ulcerative - immunology | Case-Control Studies | Intestines - immunology | Celiac Disease - microbiology | Escherichia coli Infections - genetics | Celiac Disease - immunology | Leukocytes, Mononuclear - immunology | Dermatitis, Atopic - immunology | Female | Cytokines - genetics | Leukocytes, Mononuclear - microbiology | Skin - pathology | Cytokines - immunology | Disease Models, Animal | Skin - immunology | Salmonella Infections - pathology | Intestines - pathology | Celiac Disease - genetics | Gene Expression Regulation - immunology | Escherichia coli - immunology | Escherichia coli Infections - microbiology | Colitis, Ulcerative - pathology | Dermatitis, Atopic - pathology | Celiac Disease - pathology | Leukocytes, Mononuclear - pathology | Salmonella - immunology | Animals | Intestines - microbiology | Colitis, Ulcerative - microbiology | Escherichia coli Infections - pathology | Dendritic Cells - microbiology | Escherichia coli Infections - immunology | Salmonella Infections - microbiology | Mice | Protein Isoforms - immunology | Protein Isoforms - genetics | Skin | Salmonella | Food allergies | Antigens | Inflammation | Inflammatory diseases | Asthma | Inflammatory bowel disease | E coli | Biopsy | Lymphocytes | Rodents | Software | Laboratory animals | Index Medicus | Abridged Index Medicus | moDC, Monocyte-derived dendritic cell | NF-κB, Nuclear factor κB | TLR, Toll-like receptor | AD, Atopic dermatitis | STAT5, Signal transducer and activator of transcription 5 | mDC, Myeloid dendritic cell | shTSLP, Short isoform thymic stromal lymphopoietin | UC, Ulcerative colitis | CD, Celiac disease | DSS, Dextran sodium sulfate | DC, Dendritic cell | poly I:C, Polyinosinic:polycytidylic acid | TSLP, Thymic stromal lymphopoietin | MAPK, Mitogen-activated protein kinase | lTSLP, Long isoform thymic stromal lymphopoietin | TSLPR, Thymic stromal lymphopoietin receptor | Mechanisms of Allergy and Clinical Immunology
Journal Article
Journal Article