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PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, pp. e0136822 - e0136822
Methionine metabolism plays a central role in methylation reactions, production of glutathione and methylarginines, and modulating homocysteine levels. The... 
AMINO-ACID-METABOLISM | OXIDATIVE STRESS | DNA METHYLATION | LIQUID-CHROMATOGRAPHY | NITRIC-OXIDE SYNTHASE | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | FOLLOW-UP | STEATOHEPATITIS | ONE-CARBON METABOLISM | MASS-SPECTROMETRY | Glycine N-Methyltransferase - metabolism | Blood Chemical Analysis | Homocysteine - metabolism | Glutathione - biosynthesis | Diet, High-Fat | Female | Metabolic Networks and Pathways - physiology | Cysteine - metabolism | Dipeptides - metabolism | Betaine-Homocysteine S-Methyltransferase - metabolism | Acyl Coenzyme A - metabolism | B-Lymphocytes - metabolism | Methionine - metabolism | Liver - metabolism | Mice, Inbred C57BL | Metabolome | Adenosylhomocysteinase - metabolism | Methionine Adenosyltransferase - metabolism | DNA Methylation - genetics | Non-alcoholic Fatty Liver Disease - metabolism | Cystathionine beta-Synthase - metabolism | Random Allocation | Animals | 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase - metabolism | Mice | Fatty liver | Physiological aspects | Development and progression | Genetic aspects | Research | Homocysteine | Amino acid metabolism | Transcription factors | Adenosylmethionine | High cholesterol diet | Bcl-2 protein | Laboratories | Liver | Glycine | Caspase-3 | Proteins | Elevation | Arginine | Betaine | Rodents | DNA methylation | Deoxyribonucleic acid--DNA | Glutathione | Phosphatidylethanolamine | Liver diseases | Nutrition | 5-Methyltetrahydrofolate-homocysteine S-methyltransferase | Methionine | Glycine N-methyltransferase | c-Jun protein | Caspase | Betaine-homocysteine S-methyltransferase | Gene expression | Metabolism | Fatty acids | Lymphoma | Fatty-acid synthase | Cholesterol | Molecular chains | Substrates | Depletion | Lymphocytes B | Diet | Nitric oxide | Fibrosis | DNA methyltransferase | Methylation | Nuclear reactions | Polymethyl methacrylate | B-cell lymphoma | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
American Journal of Physiology - Endocrinology and Metabolism, ISSN 0193-1849, 04/2016, Volume 310, Issue 8, pp. E624 - E632
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 08/2015, Volume 96, Issue 3, pp. 256 - 266
Journal Article
American Journal of Physiology - Renal Physiology, ISSN 1931-857X, 08/2009, Volume 297, Issue 2, pp. 410 - 419
Elevated level of homocysteine (Hcy), known as hyperhomocysteinemia (HHcy), is associated with end-stage renal diseases. Hcy metabolizes in the body to produce... 
Cystathionine-γ lyase | Matrix metalloproteinase | Homocysteine | Cystathionine-β synthase | homocysteine | PHYSIOLOGY | RAT | H2S | cystathionine-beta synthase | GLOMERULAR INJURY | PROTECTS | MURINE MODEL | PODOCYTE INJURY | INDUCED OXIDATIVE STRESS | UROLOGY & NEPHROLOGY | matrix metalloproteinase | cystathionine-gamma lyase | PPAR-GAMMA AGONIST | EXPRESSION | Hydrogen Sulfide - metabolism | Kidney - pathology | Apoptosis - drug effects | Glutathione - metabolism | Antioxidants - metabolism | Hyperhomocysteinemia - metabolism | Male | Glutathione Disulfide - metabolism | Proteinuria - prevention & control | Kidney - metabolism | Matrix Metalloproteinase 9 - metabolism | Nephrectomy | Superoxides - metabolism | Membrane Proteins - metabolism | Sulfides - metabolism | Cystathionine beta-Synthase - genetics | Disease Models, Animal | Sulfides - pharmacology | Kidney - drug effects | Matrix Metalloproteinase 2 - metabolism | Mice, Inbred C57BL | Homocysteine - blood | Proteinuria - metabolism | Antioxidants - pharmacology | Cystathionine beta-Synthase - metabolism | Hydrogen Sulfide - blood | Hyperhomocysteinemia - drug therapy | Kidney Failure, Chronic - metabolism | Mice, Knockout | Kidney Failure, Chronic - genetics | Animals | Kidney Failure, Chronic - prevention & control | Desmin - metabolism | Hyperhomocysteinemia - genetics | Mice | Oxidative Stress - drug effects | Hydrogen sulfide | Proteins | Antioxidants | Plasma | Rodents | Kidney diseases | Apoptosis | Index Medicus | cystathionine-β synthase | cystathionine-γ lyase
Journal Article
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, ISSN 1552-4868, 02/2011, Volume 157, Issue 1, pp. 33 - 44
Derivatives of cobalamin (vitamin B 12 ) are required for activity of two enzymes in humans. Adenosylcobalamin is required for activity of mitochondrial... 
methylmalonic acidemia | vitamin B12 | cobalamin | homocystinuria | transcobalamin | Methylmalonic acidemia | Cobalamin | Transcobalamin | Homocystinuria | Vitamin B12 | HEREDITARY MEGALOBLASTIC-ANEMIA | HOMOCYSTINURIA CBLC | COMBINED METHYLMALONIC ACIDURIA | INTRINSIC-FACTOR GENE | METHIONINE SYNTHASE REDUCTASE | CBLB COMPLEMENTATION GROUP | METHYLCOBALAMIN DEFICIENCY | GENETICS & HEREDITY | TRANSCOBALAMIN-I HAPTOCORRIN | VITAMIN-B-12 METABOLISM | MOUSE GASTRULATION | Malabsorption Syndromes - diagnosis | Methylmalonic Acid - blood | Humans | Vitamin B 12 - analogs & derivatives | Hyperhomocysteinemia - metabolism | Malabsorption Syndromes - metabolism | Neonatal Screening | Amino Acid Metabolism, Inborn Errors - diagnosis | Methylmalonyl-CoA Mutase - metabolism | Amino Acid Metabolism, Inborn Errors - metabolism | Homocysteine - urine | Anemia, Megaloblastic | Proteinuria - diagnosis | Vitamin B 12 Deficiency - metabolism | Infant, Newborn | Methylmalonic Acid - urine | Cobamides - metabolism | Vitamin B 12 Deficiency - diagnosis | Metabolism, Inborn Errors - metabolism | Homocysteine - blood | Proteinuria - metabolism | Methylmalonyl-CoA Mutase - deficiency | Metabolism, Inborn Errors - diagnosis | Vitamin B 12 Deficiency - genetics | Hyperhomocysteinemia - diagnosis | Vitamin B 12 - metabolism | Thrombocytopenia | Urine | homocysteine | Enzymes | 5-Methyltetrahydrofolate-homocysteine S-methyltransferase | Anemia | adenosylcobalamin | Blood | Psychosis | Mitochondria | Dementia disorders | Complementation | Degeneration | Metabolic acidosis | Neutropenia | Index Medicus
Journal Article
MOLECULAR NEUROBIOLOGY, ISSN 0893-7648, 05/2016, Volume 53, Issue 4, pp. 2451 - 2467
Elevated plasma total homocysteine (Hcy) level is associated with an increased risk of Alzheimer's disease (AD). During transsulfuration pathways, Hcy is... 
Cerebrovascular pathology | COGNITIVE PERFORMANCE | NEUROSCIENCES | MATRIX METALLOPROTEINASES | INDUCED MEMORY IMPAIRMENT | RISK-FACTOR | Blood-brain barrier dysfunction | RECEPTOR TRAFFICKING | MATRIX-METALLOPROTEINASE-9 | RAT-BRAIN | Homocysteine | Alzheimer's disease | PLASMA HOMOCYSTEINE | EXPRESSION | Dementia | Memory - drug effects | Glial Fibrillary Acidic Protein - genetics | Cadherins - metabolism | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Blood-Brain Barrier - physiopathology | Claudin-5 - metabolism | Microvessels - pathology | Male | Synapses - pathology | Glial Fibrillary Acidic Protein - metabolism | RNA, Messenger - metabolism | Antigens, CD - genetics | Alzheimer Disease - pathology | Antigens, CD - metabolism | Matrix Metalloproteinase 9 - metabolism | Cadherins - genetics | Synapses - drug effects | Alzheimer Disease - physiopathology | Hydrogen Sulfide - pharmacology | Cerebrovascular Circulation - drug effects | Matrix Metalloproteinase 2 - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Alzheimer Disease - drug therapy | Microvessels - drug effects | Claudin-5 - genetics | Cystathionine beta-Synthase - metabolism | Permeability | Blood-Brain Barrier - drug effects | Nerve Tissue Proteins - genetics | Blood-Brain Barrier - metabolism | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Blood-Brain Barrier - pathology | Hydrogen Sulfide - therapeutic use | Intercellular Adhesion Molecule-1 - metabolism | Animals | Intercellular Adhesion Molecule-1 - genetics | Avoidance Learning - drug effects | Alzheimer Disease - genetics | Dizocilpine Maleate - pharmacology | Hydrogen sulfide | Methyl aspartate | Brain | RNA | Neurons | Intermediate filament proteins | Index Medicus | cerebrovascular pathology | dementia | blood brain barrier dysfunction
Journal Article
Environmental Health Perspectives, ISSN 0091-6765, 2/2011, Volume 119, Issue 2, pp. 182 - 188
Journal Article
International Journal of Cancer, ISSN 0020-7136, 03/2019, Volume 144, Issue 5, pp. 947 - 956
Journal Article
British Journal of Nutrition, ISSN 0007-1145, 10/2014, Volume 112, Issue 8, pp. 1274 - 1285
During the last few decades, plant protein ingredients such as soya proteins have replaced fishmeal in the diets of aquacultured species. This may affect the... 
Taurine | Methionine | Atlantic salmon | Trans-sulphuration | Spermine/spermidine acetyltransferase | Polyamine turnover | S-Adenosylmethionine decarboxylase | HOMOCYSTEINE | LIPID-METABOLISM | CHOLINE | SALAR L | TAURINE SUPPLEMENTATION | ENZYMATIC-HYDROLYSIS | AMINO-ACID | NUTRITION & DIETETICS | Spermine | spermidine acetyltransferase | LIVER | MICE | EXPRESSION | Acetyltransferases - metabolism | Liver - pathology | Ornithine Decarboxylase - metabolism | Diet - adverse effects | Adenosylmethionine Decarboxylase - metabolism | Salmo salar - metabolism | Muscle, Skeletal - metabolism | Adenosylmethionine Decarboxylase - genetics | Salmo salar - growth & development | Acetyltransferases - genetics | Liver - growth & development | Methionine - therapeutic use | Fish Proteins - genetics | Gene Expression Regulation, Developmental | Weight Gain | Diet - veterinary | Methionine - deficiency | Ornithine Decarboxylase - genetics | Methionine - metabolism | Liver - metabolism | Deficiency Diseases - metabolism | Fish Proteins - metabolism | Lipid Metabolism | Deficiency Diseases - prevention & control | Energy Intake | Plant Proteins - adverse effects | Polyamines - metabolism | Animals | Norway | Spermine - metabolism | Deficiency Diseases - veterinary | Muscle, Skeletal - pathology | S-Adenosylmethionine - metabolism | Aquaculture | Putrescine - metabolism | Amino acids | Biochemistry | Diet | Nutrition | Feeds | Salmon | Index Medicus | Spermine/ spermidine acetyltransferase
Journal Article
BioFactors, ISSN 0951-6433, 05/2017, Volume 43, Issue 3, pp. 434 - 450
Hyperomocysteinemia (HHcy) has been associated with mild cognitive impairment and dementia. Hydrogen sulfide (H 2 S) has been suggested to be an endogenous... 
homocysteine | hyperhomocysteinemia | catecholamines | hydrogen sulfide | behavior | neurotransmitters | NERVOUS-SYSTEM | OXIDATIVE STRESS | RAT | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MORRIS WATER MAZE | AMYOTROPHIC-LATERAL-SCLEROSIS | ENDOPLASMIC-RETICULUM STRESS | ENDOCRINOLOGY & METABOLISM | HEPATIC-ENCEPHALOPATHY | PARKINSONS-DISEASE | Hydrogen Sulfide - metabolism | Gene Expression - drug effects | Hyperhomocysteinemia - metabolism | Cystathionine gamma-Lyase - metabolism | Male | Homocysteine - metabolism | Monoamine Oxidase - genetics | Cerebral Cortex - metabolism | Cerebral Cortex - physiopathology | Injections, Subcutaneous | Homocysteine - administration & dosage | Sulfides - metabolism | Cognitive Dysfunction - complications | Cystathionine gamma-Lyase - genetics | Cystathionine beta-Synthase - genetics | Dopamine - metabolism | Locomotion - drug effects | Sulfides - pharmacology | Cognitive Dysfunction - drug therapy | Hydrogen Sulfide - pharmacology | Cognitive Dysfunction - metabolism | Rats | Cystathionine beta-Synthase - metabolism | Cognition - drug effects | Maze Learning - drug effects | Rats, Sprague-Dawley | Hyperhomocysteinemia - drug therapy | Hippocampus - metabolism | Rotarod Performance Test | Animals | Norepinephrine - metabolism | Serotonin - metabolism | Cognitive Dysfunction - chemically induced | Hippocampus - physiopathology | Hyperhomocysteinemia - chemically induced | Hyperhomocysteinemia - complications | Epinephrine - metabolism | Monoamine Oxidase - metabolism | Hydrogen sulfide | Catecholamines | Homocysteine | Animal behavior | Index Medicus
Journal Article