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Journal of Clinical Investigation, ISSN 0021-9738, 07/2013, Volume 123, Issue 7, pp. 2948 - 2960
Hormone therapies for advanced prostate cancer target the androgen receptor (AR) ligand-binding domain (LBD), but these ultimately fail and the disease... 
MEDICINE, RESEARCH & EXPERIMENTAL | SIGNAL-TRANSDUCTION PATHWAYS | CELLS | TRANSCRIPTIONAL ACTIVATION | PROTEIN | ANTIANDROGEN | GENE-EXPRESSION | TRANSACTIVATION DOMAIN | TUMOR-GROWTH | PROGRESSION | HORMONE RECEPTORS | Prostatic Neoplasms - metabolism | Stereoisomerism | Humans | Receptors, Androgen - metabolism | Transcriptional Activation - drug effects | Cercopithecus aethiops | Male | Androgen Receptor Antagonists - pharmacology | Benzhydryl Compounds - chemistry | Luciferases - genetics | Androgen Receptor Antagonists - chemistry | Receptors, Androgen - chemistry | Chlorohydrins - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Genes, Reporter | Prostatic Neoplasms - drug therapy | Protein Structure, Tertiary | Prostatic Neoplasms - pathology | Gene Expression | Antineoplastic Agents, Hormonal - pharmacology | Click Chemistry | Mice, SCID | Chlorohydrins - chemistry | Orchiectomy | Xenograft Model Antitumor Assays | Animals | Receptors, Androgen - genetics | Tumor Burden - drug effects | Protein Binding | Mice, Inbred NOD | Benzhydryl Compounds - pharmacology | Cell Proliferation - drug effects | Mice | Antineoplastic Agents, Hormonal - chemistry | COS Cells | Luciferases - biosynthesis | Antagonists (Biochemistry) | Care and treatment | Androgens | Physiological aspects | Prostate cancer | Health aspects | Methods | Cancer | Proteins | Medical research | Ligands | Kinases | Gene expression | Experiments | Drug dosages | Tumors
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 09/2015, Volume 373, Issue 10, pp. 980 - 981
To the Editor: We disagree with Berl's discussion, in his review on vasopressin antagonists (June 4 issue), 1 about the availability and adverse effects of... 
MEDICINE, GENERAL & INTERNAL | UREA | Antidiuretic Hormone Receptor Antagonists - pharmacology | Vasopressins - physiology | Humans | Hyponatremia - drug therapy | Antidiuretic Hormone Receptor Antagonists - therapeutic use | Edema | Urea | Meniere's disease | Side effects | Hyponatremia | Secretion | Ulcers | Antagonists | Heart diseases | Vasopressin | Gastritis
Journal Article
Biological Psychiatry, ISSN 0006-3223, 2010, Volume 67, Issue 9, pp. 831 - 839
Journal Article
Neuron, ISSN 0896-6273, 06/2012, Volume 74, Issue 5, pp. 801 - 808
The steroid 17β-estradiol (E2) is well known to influence hippocampal functions such as memory, affective behaviors, and epilepsy. There is growing awareness... 
CA1 | EXCITABILITY | STEROIDS | SYNAPSES | ESTROGEN-RECEPTOR-ALPHA | SYNAPTIC-TRANSMISSION | NEURONS | RELEASE | BINDING | NEUROSCIENCES | Cannabinoid Receptor Modulators - metabolism | CA1 Region, Hippocampal - cytology | Electric Stimulation | Estrogens - pharmacology | Male | Receptors, Metabotropic Glutamate - metabolism | Pyridazines - pharmacology | Lactones - pharmacology | Dose-Response Relationship, Drug | Drug Interactions | Castration | Piperidines - pharmacology | Excitatory Amino Acid Agents - pharmacology | Neurons - physiology | Female | Neurons - drug effects | Endocannabinoids | Estradiol - pharmacology | Pyrazoles - pharmacology | Enzyme Inhibitors - pharmacology | NAD - pharmacology | Cannabinoid Receptor Modulators - agonists | Morpholines - pharmacology | Rats | Biophysics | Rats, Sprague-Dawley | GABA Antagonists - pharmacology | Naphthalenes - pharmacology | Patch-Clamp Techniques | Animals | Benzoxazines - pharmacology | Cannabinoid Receptor Modulators - antagonists & inhibitors | Phenols | In Vitro Techniques | Neural Inhibition - drug effects | Benzodioxoles - pharmacology | Inhibitory Postsynaptic Potentials - drug effects | Brain | Epilepsy | Estrogen | GABA | Hormones, Sex | Estradiol | Studies | Rodents | Gender differences | Behavior | Males | Females | Presynapse | Emotional behavior | gamma -Aminobutyric acid | Neurosteroids | Memory | Sex | Estrogen receptors | Cannabinoid CB1 receptors | Anandamide | Synaptic transmission | Hippocampus | Steroid hormones | Synapses
Journal Article
Neuron, ISSN 0896-6273, 02/2012, Volume 73, Issue 3, pp. 553 - 566
The hypothalamic neuropeptide oxytocin (OT), which controls childbirth and lactation, receives increasing attention for its effects on social behaviors, but... 
SUPRAOPTIC NUCLEI | RAT | CENTRAL NUCLEUS | IN-VIVO | NEURONS | VASOPRESSIN | SOCIAL BEHAVIORS | CONDITIONED FEAR | BRAIN OXYTOCIN | STRESS | NEUROSCIENCES | Action Potentials - genetics | Lactation | Rats, Wistar | Neurons - cytology | Phosphopyruvate Hydratase - metabolism | Green Fluorescent Proteins - genetics | Oxytocin - metabolism | Behavior, Animal | Quinoxalines - pharmacology | Time Factors | Light | Axons - ultrastructure | Female | Fiber Optic Technology - methods | Inhibition (Psychology) | Microscopy, Electron, Transmission | Oxytocin - antagonists & inhibitors | Conditioning (Psychology) - physiology | Vesicular Glutamate Transport Protein 2 - metabolism | Axons - metabolism | Rats | Vasotocin - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Vasotocin - analogs & derivatives | GABA Antagonists - pharmacology | Gene Expression Regulation - drug effects | Fear | Patch-Clamp Techniques | Animals | Hypothalamus - metabolism | Rhodopsin - genetics | Analysis of Variance | Hypothalamus - cytology | Models, Biological | Prosencephalon - cytology | Picrotoxin - pharmacology | Genetic Vectors - physiology | In Vitro Techniques | Amygdala - physiology | Neurosciences | Pituitary hormones | Neurons | Oncology, Experimental | GABA | Research | Cancer | Rhodopsin | Brain research | Rodents | Pituitary gland | Behavior | Mammals | Gene expression | Experiments | Life Sciences | Neuroscience | Cognitive science | Neurons and Cognition
Journal Article
Nature Neuroscience, ISSN 1097-6256, 11/2013, Volume 16, Issue 11, pp. 1637 - 1643
Journal Article
Cell Reports, ISSN 2211-1247, 09/2015, Volume 12, Issue 12, pp. 1968 - 1977
Breast cancers (BCs) typically express estrogen receptors (ERs) but frequently exhibit de novo or acquired resistance to hormonal therapies. Here, we show that... 
NOTCH | ESTROGEN | ADJUVANT TAMOXIFEN | RECEPTOR | CELL BIOLOGY | Estradiol - analogs & derivatives | Receptors, Estrogen - metabolism | Neoplastic Stem Cells - drug effects | Receptors, Notch - metabolism | Homeodomain Proteins - metabolism | Humans | Retinal Dehydrogenase - metabolism | p-Aminoazobenzene - analogs & derivatives | Receptors, Notch - genetics | Receptors, Notch - antagonists & inhibitors | Basic Helix-Loop-Helix Transcription Factors - metabolism | Neoplastic Stem Cells - metabolism | Serrate-Jagged Proteins | p-Aminoazobenzene - pharmacology | Neoplastic Stem Cells - pathology | Estradiol - pharmacology | Jagged-1 Protein | Basic Helix-Loop-Helix Transcription Factors - genetics | Signal Transduction | Isoenzymes - genetics | Membrane Proteins - genetics | Cell Cycle Proteins - metabolism | Benzazepines - pharmacology | Retinal Dehydrogenase - genetics | Breast Neoplasms - drug therapy | Drug Resistance, Neoplasm - genetics | Breast Neoplasms - genetics | Survival Analysis | Cell Line, Tumor | Retinal Dehydrogenase - antagonists & inhibitors | Mice | Calcium-Binding Proteins - genetics | Transcription Factor HES-1 | Gene Expression Regulation, Neoplastic | Cell Cycle Proteins - antagonists & inhibitors | Estrogen Receptor Antagonists - pharmacology | Intercellular Signaling Peptides and Proteins - metabolism | Isoenzymes - metabolism | Cell Cycle Proteins - genetics | Female | Membrane Proteins - metabolism | Calcium-Binding Proteins - metabolism | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Receptors, Estrogen - genetics | Antineoplastic Agents, Hormonal - pharmacology | Intercellular Signaling Peptides and Proteins - genetics | Proto-Oncogene Proteins - genetics | Basic Helix-Loop-Helix Transcription Factors - antagonists & inhibitors | Homeodomain Proteins - genetics | Xenograft Model Antitumor Assays | Animals | Breast Neoplasms - pathology | Homeodomain Proteins - antagonists & inhibitors | Tamoxifen - pharmacology | Breast Neoplasms - mortality | Cell Proliferation - drug effects | Isoenzymes - antagonists & inhibitors | Receptor, Notch4 | Drug Resistance, Neoplasm - drug effects | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Cancer and Oncology | Medicin och hälsovetenskap | Cancer och onkologi
Journal Article
Pharmacological reviews, ISSN 0031-6997, 2015, Volume 67, Issue 1, pp. 214 - 258
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 08/2009, Volume 27, Issue 23, pp. 3742 - 3748
Journal Article