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PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 10, p. e13590
Journal Article
Genes and Development, ISSN 0890-9369, 10/2003, Volume 17, Issue 19, pp. 2436 - 2449
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 11/2015, Volume 88, Issue Pt B, pp. 417 - 426
In light of the emerging interplay between redox and metabolic signaling pathways we investigated the potential cross talk between nuclear factor E2-related... 
Xanthohumol | Nrf2 | ER stress | AMPK | HO-1 | PERK | LKB1 | MEF | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | MECHANISMS | ENERGY SENSOR | CELL DEFENSE PATHWAY | ENDOTHELIAL-CELLS | ENDOCRINOLOGY & METABOLISM | NRF2-MEDIATED INDUCTION | HEME OXYGENASE-1 | STRESS | AMP-Activated Protein Kinases - metabolism | Heme Oxygenase-1 - metabolism | Reactive Oxygen Species - metabolism | Oxidation-Reduction | Oxidative Stress - physiology | Propiophenones - pharmacology | Mitochondria - metabolism | Mitochondria - drug effects | Receptor Cross-Talk - physiology | Blotting, Western | Animals | Flow Cytometry | Fibroblasts - drug effects | NF-E2-Related Factor 2 - metabolism | Signal Transduction - physiology | Flavonoids - pharmacology | Membrane Proteins - metabolism | Mice | Real-Time Polymerase Chain Reaction | Unfolded Protein Response - physiology | Fibroblasts - metabolism | RNA | Glycogen | Synthesis | ACC, acetyl-CoA carboxylase | CHO, Chinese hamster ovary | GSH, glutathione (reduced) | OCR, oxygen consumption rate | HO-1, heme oxygenase 1 | CaMKK, calcium calmodulin-dependent kinase kinase | Maf, small musculoaponeurotic fibrosarcoma | PERK, protein kinase RNA-like endoplasmic reticulum kinase | Xn, xanthohumol | Hrd1, synoviolin | TAK, transforming growth factor β-activated kinase | UPR, unfolded protein response | Hrd1 (HMG-CoA reductase degradation)-ubiquitin ligase | MEF, mouse embryonic fibroblasts | βTrcP1, β-transducin-repeat containing protein 1 | mTOR, mammalian target of rapamycin | ROS, reactive oxygen species | LKB1, liver kinase B1 | Keap1, Kelch-like ECH-associated protein | GSSG, oxidized glutathione | ARE, antioxidant response element | WT, wild type | GSK3β, glycogen synthase kinase 3β | Nrf2, nuclear factor E2-related factor 2 | AMPK, AMP-activated kinase | DCF, dichlorofluorescein | NADPH, nicotinamide adenine dinucleotide phosphate | DMSO, dimethyl sulfoxide | ER, endoplasmic reticulum | FCS, fetal calf serum
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 12/2018, Volume 1864, Issue 12, pp. 3615 - 3622
To explore the underlying mechanisms of Hrd1/sema3a/IGF-1R on cardiomyocyte apoptosis. AMI model was established by the left-anterior descending coronary... 
Cardiomyocyte apoptosis | sema3a | IGF-1R | Hrd1 | AMI | PROTEIN | MYOCARDIAL-INFARCTION | CANCER CELLS | PROTECTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | RATS | ISCHEMIA | SEMAPHORIN 3A | SYNOVIOLIN | BIOPHYSICS | INFLAMMATION | SUPPRESSES
Journal Article
Genes and Development, ISSN 0890-9369, 04/2014, Volume 28, Issue 7, pp. 708 - 722
Journal Article
Cellular Signalling, ISSN 0898-6568, 10/2018, Volume 50, pp. 90 - 99
The tyrosine phosphatases family member PTEN is a tumor suppressor which is widely expressed throughout the body and is involved in a variety of biological... 
PTEN | HCC | Ubiquitination | HRD1 | EMBRYONIC-DEVELOPMENT | TRANSCRIPTION | TUMOR-SUPPRESSOR GENE | BREAST | CELL BIOLOGY | SYNOVIOLIN | ENDOPLASMIC-RETICULUM | CANCER STATISTICS | EXPRESSION | E3 UBIQUITIN LIGASE | Ubiquitin | Tyrosine | Medical colleges | Phosphatases | Ligases | Development and progression | Hepatoma | Cells
Journal Article
Allergy, Asthma and Immunology Research, ISSN 2092-7355, 11/2018, Volume 10, Issue 6, pp. 698 - 715
Purpose: Hrd1 has recently emerged as a critical regulator of B-cells in autoimmune diseases. However, its role in the pathogenesis of chronic rhinosinusitis... 
B-cells | Innate immunity | Chronic rhinosinusitis | Nasal polyps | Hrd1 | PATHOGENESIS | SYNOVIOLIN | innate immunity | ALLERGY | INFLAMMATION | chronic rhinosinusitis | nasal polyps | DEGRADATION | UBIQUITIN LIGASE HRD1 | IMMUNOLOGY | Original | 내과학
Journal Article
Journal Article
Journal Article