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Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 8, pp. 2687 - 2700
The microtubule-associated protein tau forms insoluble, amyloid-type aggregates in various dementias, most notably Alzheimer's disease. Cellular chaperone... 
HEAT-SHOCK PROTEINS | NEUROFIBRILLARY TANGLES | OXIDATIVE STRESS | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | FRONTOTEMPORAL DEMENTIA | PAIRED HELICAL FILAMENTS | ALPHA-B-CRYSTALLIN | PLASTICITY DEFICITS | BETA-STRUCTURE | AGGREGATION | HSP27 Heat-Shock Proteins - chemistry | HSC70 Heat-Shock Proteins - metabolism | Humans | tau Proteins - metabolism | Amyloid - chemistry | Amyloid - ultrastructure | HSC70 Heat-Shock Proteins - ultrastructure | Recombinant Fusion Proteins - metabolism | tau Proteins - chemistry | HSP27 Heat-Shock Proteins - genetics | HSP27 Heat-Shock Proteins - ultrastructure | Protein Isoforms - metabolism | tau Proteins - genetics | Amyloid - metabolism | Protein Aggregation, Pathological - pathology | Protein Aggregation, Pathological - prevention & control | Protein Isoforms - chemistry | Amyloid - drug effects | Protein Interaction Domains and Motifs | Dimerization | Heparin - pharmacology | tau Proteins - ultrastructure | HSC70 Heat-Shock Proteins - genetics | Solubility | Models, Molecular | Recombinant Fusion Proteins - chemistry | Down-Regulation - drug effects | Amino Acid Motifs | Cryoelectron Microscopy | HSC70 Heat-Shock Proteins - chemistry | Anticoagulants - pharmacology | HSP27 Heat-Shock Proteins - metabolism | Kinetics | Mutation | Protein Aggregation, Pathological - metabolism | Amino Acid Substitution | Index Medicus | Protein Structure and Folding | amyloid | chaperone | 70 kilodalton heat shock protein (Hsp70) | tau | aggregation | small heat shock protein (sHsp)
Journal Article
Brain Research, ISSN 0006-8993, 05/2006, Volume 1089, Issue 1, pp. 67 - 78
Small heat shock proteins Hsp20 and HspB2/B3 co-localize with Aβ deposition in senile plaques and cerebral amyloid angiopathy in Alzheimer's disease brains,... 
Cerebrovascular amyloid | Amyloid-β protein | Small heat shock protein | Alzheimer's disease | Fibrillization | HSPB8 | ALPHA-B-CRYSTALLIN | ALZHEIMERS-DISEASE BRAINS | CHAPERONE | NEUROSCIENCES | VESSEL WALL | HUMAN BRAIN PERICYTES | fibrillization | IN-VITRO | small heat shock protein | A-BETA | amyloid-beta protein | SMOOTH-MUSCLE-CELLS | cerebrovascular amyloid | EXPRESSION | Protein Binding - genetics | Humans | Neoplasm Proteins - pharmacology | Cerebral Amyloid Angiopathy - metabolism | Neoplasm Proteins - metabolism | alpha-Crystallins - metabolism | HSP20 Heat-Shock Proteins - metabolism | Neuroprotective Agents - metabolism | HSP20 Heat-Shock Proteins - pharmacology | Neuroprotective Agents - pharmacology | Amyloid beta-Peptides - genetics | Amyloid beta-Peptides - metabolism | Peptide Fragments - genetics | Alzheimer Disease - physiopathology | Peptide Fragments - metabolism | Plaque, Amyloid - pathology | Cerebral Amyloid Angiopathy - physiopathology | Heat-Shock Proteins - metabolism | Cells, Cultured | Cerebral Arteries - physiopathology | Heat-Shock Proteins - pharmacology | Mutation - genetics | Amyloid beta-Peptides - antagonists & inhibitors | alpha-Crystallins - pharmacology | Cerebral Arteries - metabolism | Peptide Fragments - antagonists & inhibitors | Alzheimer Disease - metabolism | Plaque, Amyloid - metabolism | Amyloid beta-Peptides - chemistry | HSP27 Heat-Shock Proteins | Index Medicus
Journal Article
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, ISSN 0892-6638, 11/2017, Volume 31, Issue 11, pp. 4720 - 4733
Before the onset of sprouting angiogenesis, the endothelium is prepatterned for the positioning of tip and stalk cells. Both cell identities are not static, as... 
cell migration | ALK2 | ALK3 | p38 MAPK | SMAD1/5 | MIGRATION | ACTIVATION | TGF-BETA | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | NOTCH | CANCER | ALK1 | CELL BIOLOGY | ENDOTHELIAL-CELLS | BIOLOGY | GROWTH-FACTOR | EXPRESSION | MAP Kinase Signaling System - physiology | Human Umbilical Vein Endothelial Cells - metabolism | Humans | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Vascular Endothelial Growth Factor Receptor-2 - genetics | HSP27 Heat-Shock Proteins - genetics | Intercellular Signaling Peptides and Proteins - metabolism | Bone Morphogenetic Protein 6 - genetics | Smad5 Protein - metabolism | Bone Morphogenetic Protein 2 - metabolism | Human Umbilical Vein Endothelial Cells - cytology | Smad1 Protein - genetics | p38 Mitogen-Activated Protein Kinases - metabolism | Smad5 Protein - genetics | Bone Morphogenetic Protein 2 - genetics | Intercellular Signaling Peptides and Proteins - genetics | Bone Morphogenetic Protein Receptors, Type I - genetics | Vascular Endothelial Growth Factor Receptor-2 - metabolism | p38 Mitogen-Activated Protein Kinases - genetics | Activin Receptors, Type I - metabolism | Bone Morphogenetic Protein Receptors, Type I - metabolism | Activin Receptors, Type I - genetics | Neovascularization, Physiologic - physiology | Bone Morphogenetic Protein 6 - metabolism | HSP27 Heat-Shock Proteins - metabolism | Smad1 Protein - metabolism | Complex formation | Genes | Clinical trials | Cell adhesion & migration | Proteins | Angiogenesis | Signal transduction | Receptors | Pathways | Bone morphogenetic proteins | Vascular endothelial growth factor | Protein-tyrosine kinase | Enhancer-of-split protein | Bone morphogenetic protein 6 | Tyrosine | Medical research | Bone morphogenetic protein 2 | Heat shock proteins | Gene expression | Spheroids | Endothelial cells | Bone morphogenetic protein receptor type I | Endothelium | Signaling | Antiangiogenics | Hsp27 protein | Bone | Activin | Cell migration | Heat shock | Index Medicus | SMAD1 | 5 | Research
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2017, Volume 292, Issue 24, pp. 9944 - 9957
Journal Article
Microvascular Research, ISSN 0026-2862, 2011, Volume 81, Issue 2, pp. 189 - 197
Acute lung injury (ALI) results from loss of alveolar-capillary barrier integrity and the evolution of high-permeability pulmonary edema resulting in alveolar... 
Acute lung injury | MAP kinase | HMGB1 | RAGE | Hsp27 | Endothelium | ACTIVATION | PERMEABILITY | HEAT-SHOCK PROTEIN-27 | RECEPTOR | GROUP BOX-1 PROTEIN | RESPIRATORY-DISTRESS-SYNDROME | P38 MAP KINASE | TUMOR-NECROSIS-FACTOR | PERIPHERAL VASCULAR DISEASE | DYSFUNCTION | GLYCATION END-PRODUCTS | Capillary Permeability - physiology | RNA, Small Interfering - genetics | Cadherins - metabolism | Stress Fibers - drug effects | Humans | Actins - metabolism | Capillary Permeability - drug effects | Intracellular Signaling Peptides and Proteins - metabolism | HMGB1 Protein - genetics | Antigens, CD - metabolism | HMGB1 Protein - pharmacology | Actin Cytoskeleton - drug effects | p38 Mitogen-Activated Protein Kinases - metabolism | Phosphorylation - drug effects | Receptor for Advanced Glycation End Products - genetics | Intracellular Signaling Peptides and Proteins - genetics | Endothelial Cells - physiology | Protein-Serine-Threonine Kinases - metabolism | Actin Cytoskeleton - metabolism | Receptor for Advanced Glycation End Products - metabolism | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | p38 Mitogen-Activated Protein Kinases - genetics | Recombinant Proteins - genetics | Electric Impedance | Recombinant Proteins - pharmacology | Pulmonary Artery - cytology | Stress Fibers - metabolism | Signal Transduction - drug effects | Endothelial Cells - cytology | Models, Biological | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Cytoskeleton - metabolism | HSP27 Heat-Shock Proteins - metabolism | Signal Transduction - physiology | Protein Kinase Inhibitors - pharmacology | Gap Junctions - drug effects | Cytoskeleton - drug effects | Endothelial Cells - drug effects | Acute respiratory distress syndrome | Heat shock proteins | Chromosomal proteins | Permeability | Index Medicus | endothelium | acute lung injury
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 688 - 15
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 12/2006, Volume 203, Issue 13, pp. 2793 - 2799
The ataxia telangiectasia mutated (ATM) kinase is a key tumor suppressor that regulates numerous cell cycle checkpoints as well as apoptosis. Here, we report... 
MEDICINE, RESEARCH & EXPERIMENTAL | APOPTOSIS | PATHWAY | ATM ACTIVATION | IMMUNOLOGY | CELL-CYCLE CHECKPOINTS | PPM1D | ATAXIA-TELANGIECTASIA | AUTOPHOSPHORYLATION | CANCER | TUMORIGENESIS | P53 | Phosphorylation | Cell Proliferation | Phosphoprotein Phosphatases - metabolism | Apoptosis - genetics | Neoplasm Proteins - metabolism | Tumor Suppressor Protein p53 - genetics | DNA-Binding Proteins - metabolism | Lymphoma - metabolism | Caspases - metabolism | Tumor Suppressor Proteins - genetics | Cell Cycle Proteins - genetics | Lymphoma - pathology | p38 Mitogen-Activated Protein Kinases - metabolism | Neoplasm Proteins - genetics | B-Lymphocytes - metabolism | Protein-Serine-Threonine Kinases - metabolism | Gene Expression | Tumor Suppressor Proteins - metabolism | Heat-Shock Proteins - metabolism | Cell Cycle Proteins - metabolism | Protein Phosphatase 2C | Protein-Serine-Threonine Kinases - genetics | Tumor Suppressor Protein p53 - metabolism | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Lymphoma - genetics | p38 Mitogen-Activated Protein Kinases - genetics | Mice, Transgenic | Ataxia Telangiectasia Mutated Proteins | DNA-Binding Proteins - genetics | Mice, Inbred Strains | Reverse Transcriptase Polymerase Chain Reaction | Caspase Inhibitors | Blotting, Western | Mice, Knockout | Animals | Phosphoprotein Phosphatases - genetics | Models, Biological | Survival Analysis | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Protein Binding | Mice | Proto-Oncogene Proteins c-myc - genetics | HSP27 Heat-Shock Proteins | Index Medicus | Brief Definitive Reports
Journal Article