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Gut, ISSN 0017-5749, 04/2009, Volume 58, Issue 4, pp. 520 - 529
Background:The antitumoral immune response is one determinant of colorectal cancer (CRC) outcome. Recent work suggests that Foxp3+CD25+CD4+ regulatory T cells... 
PLASMACYTOID DENDRITIC CELLS | REGULATORY-CELLS | SURVIVAL | FOXP3 EXPRESSION | GROWTH-FACTOR-BETA | TGF-BETA | IN-VIVO | DIFFERENTIATION | INTERLEUKIN-6 | GASTROENTEROLOGY & HEPATOLOGY | OVARIAN-CARCINOMA | T-Lymphocyte Subsets - immunology | Adenocarcinoma - pathology | Cell Proliferation | Humans | Middle Aged | Male | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Lymphocyte Activation - immunology | Immune Tolerance - immunology | Aged, 80 and over | Adult | Female | Cytokines - immunology | Neoplasm Invasiveness | Adenocarcinoma - immunology | Immunophenotyping | Colorectal Neoplasms - immunology | Forkhead Transcription Factors - analysis | Lymphocyte Count | Neoplasm Proteins - analysis | Aged | Colorectal Neoplasms - pathology | Neoplasm Staging | Cytokines - biosynthesis | Lymphocytes, Tumor-Infiltrating - immunology | Care and treatment | Immune response | Lymphocytes | Colorectal cancer | Physiological aspects | Development and progression | Research | Proteins | Antigens | Cytokines | Medical prognosis | Software | Experiments | Tumors | Cell adhesion & migration | Adenocarcinoma | Life Sciences | Lymphocytes, Tumor-Infiltrating | Immunology | Neoplasm Proteins | Immunotherapy | T-Lymphocytes, Regulatory | Colorectal Neoplasms | CD4-Positive T-Lymphocytes | T-Lymphocyte Subsets | Lymphocyte Activation | Immune Tolerance | Forkhead Transcription Factors
Journal Article
Journal Article
Journal of Surgical Oncology, ISSN 0022-4790, 05/2016, Volume 113, Issue 6, pp. 621 - 627
Journal Article
Journal Article
British Journal of Haematology, ISSN 0007-1048, 01/2013, Volume 160, Issue 2, pp. 123 - 132
Summary Gamma delta (γδ) Τ cells are non‐conventional T lymphocyte effectors that can interact with and eradicate tumour cells. Several data demonstrate that... 
gamma delta T lymphocytes | cancer | immunotherapy | monoclonal antibodies | haematological oncology | Haematological oncology | Monoclonal antibodies | Immunotherapy | Gamma delta T lymphocytes | Cancer | T-Lymphocyte Subsets - immunology | Adjuvants, Immunologic - pharmacology | Dendritic Cells - immunology | Humans | Receptors, Antigen, T-Cell, alpha-beta - analysis | Cells, Cultured - transplantation | Receptors, Antigen, T-Cell, gamma-delta - genetics | Gene Rearrangement, delta-Chain T-Cell Antigen Receptor | Mesenchymal Stromal Cells - immunology | T-Lymphocytes, Regulatory - immunology | Neoplasms - therapy | T-Lymphocytes, Cytotoxic - transplantation | T-Lymphocyte Subsets - chemistry | Diphosphonates - therapeutic use | Killer Cells, Natural - immunology | Cells, Cultured - immunology | Tumor Escape - immunology | Adaptive Immunity | T-Lymphocytes, Cytotoxic - immunology | Cells, Cultured - drug effects | Immunotherapy, Adoptive | Antigens, Neoplasm - immunology | Translational Medical Research | Clinical Trials as Topic | Immunity, Innate | T-Lymphocyte Subsets - transplantation | Immunologic Surveillance - immunology | Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor | T-Lymphocytes, Cytotoxic - chemistry | Receptors, Antigen, T-Cell, gamma-delta - analysis | Neoplasms - immunology | CD8-Positive T-Lymphocytes - immunology | Dendritic Cells - transplantation | Diphosphonates - pharmacology | Immunologic Surveillance | Tumor Escape | Killer Cells, Natural | Dendritic Cells | T-Lymphocytes, Cytotoxic | Neoplasms | CD8-Positive T-Lymphocytes | Life Sciences | Immunology | Mesenchymal Stromal Cells | Receptors, Antigen, T-Cell, alpha-beta | T-Lymphocytes, Regulatory | T-Lymphocyte Subsets | Antigens, Neoplasm | Adjuvants, Immunologic | Cells, Cultured | Diphosphonates | Receptors, Antigen, T-Cell, gamma-delta
Journal Article
Cancer Immunology, Immunotherapy, ISSN 0340-7004, 4/2014, Volume 63, Issue 4, pp. 395 - 406
The programmed death-1 (PD-1) molecule is mainly expressed on functionally “exhausted” CD8+ T cells, dampening the host antitumor immune response. We evaluated... 
Immunology | Medicine & Public Health | Oncology | Cancer Research | Breast cancer | Immune evasion | Regulatory T cells | Cancer immunotherapy | PD-1 | APOPTOSIS | PROGNOSIS | TUMOR | RISK | ANTIBODY | IMMUNOLOGY | CHEMOTHERAPY | HEPATOCELLULAR-CARCINOMA | ONCOLOGY | IMMUNOTHERAPY | CD8(+) T-LYMPHOCYTES | B7-H1 | Carcinoma, Lobular - pathology | Follow-Up Studies | Breast Neoplasms - immunology | Humans | Middle Aged | Programmed Cell Death 1 Receptor - analysis | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Regulatory - immunology | Antigens, Differentiation, T-Lymphocyte - analysis | Aged, 80 and over | Carcinoma, Ductal, Breast - pathology | Lymphocytes, Tumor-Infiltrating - chemistry | T-Lymphocytes, Regulatory - chemistry | Carcinoma, Lobular - immunology | CD8-Positive T-Lymphocytes - chemistry | Combined Modality Therapy | Carcinoma, Lobular - radiotherapy | T-Lymphocyte Subsets - pathology | Carcinoma, Ductal, Breast - radiotherapy | Forkhead Transcription Factors - analysis | Survival Analysis | CD8-Positive T-Lymphocytes - immunology | Lymphocytes, Tumor-Infiltrating - immunology | T-Lymphocyte Subsets - immunology | Breast Neoplasms - surgery | CD8-Positive T-Lymphocytes - pathology | Prognosis | Carcinoma, Ductal, Breast - immunology | Carcinoma, Ductal, Breast - mortality | Carcinoma, Lobular - mortality | T-Lymphocytes, Cytotoxic - pathology | T-Lymphocyte Subsets - chemistry | Mastectomy | Adult | Female | Radiotherapy, Adjuvant | T-Lymphocytes, Cytotoxic - immunology | Carcinoma, Ductal, Breast - surgery | Carcinoma, Lobular - surgery | Kaplan-Meier Estimate | Disease-Free Survival | Breast Neoplasms - radiotherapy | T-Lymphocytes, Cytotoxic - chemistry | Apoptosis - immunology | Lymphocytes, Tumor-Infiltrating - pathology | Breast Neoplasms - pathology | Lymphocyte Count | Breast Neoplasms - mortality | Aged
Journal Article
Scientific Reports, ISSN 2045-2322, 02/2016, Volume 6, Issue 1, p. 20254
Tumor cell-derived exosomes (TEX) suppress functions of immune cells. Here, changes in the gene profiles of primary human T lymphocytes exposed in vitro to... 
MESSENGER-RNAS | CANCER-PATIENTS | EXTRACELLULAR VESICLES | MICROENVIRONMENT | MULTIDISCIPLINARY SCIENCES | MICROVESICLES | DIAGNOSTIC BIOMARKERS | INDUCE APOPTOSIS | OVARIAN-CANCER | MODULATION | LYMPHOCYTES | Exosomes - metabolism | Neoplasms - metabolism | CD8-Positive T-Lymphocytes - cytology | T-Lymphocytes, Regulatory - metabolism | T-Lymphocyte Subsets - cytology | Humans | Culture Media, Conditioned - pharmacology | RNA, Messenger - metabolism | Antigens, CD - metabolism | Lectins, C-Type - metabolism | T-Lymphocyte Subsets - drug effects | T-Lymphocytes, Regulatory - cytology | CD8-Positive T-Lymphocytes - metabolism | Real-Time Polymerase Chain Reaction | Microscopy, Electron, Transmission | CD4-Positive T-Lymphocytes - cytology | Apyrase - metabolism | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Antigens, Differentiation, T-Lymphocyte - metabolism | Down-Regulation - drug effects | Up-Regulation - drug effects | T-Lymphocytes, Regulatory - drug effects | T-Lymphocyte Subsets - metabolism | CD8-Positive T-Lymphocytes - drug effects | Adenosine - metabolism | Neoplasms - pathology | CD4-Positive T-Lymphocytes - drug effects | Microscopy, Fluorescence | Adenosine | Dendritic cells | CD8 antigen | Gene regulation | Data processing | T cell receptors | Lymphocytes T | Gene expression | Exosomes | Cell surface | CD4 antigen | Polymerase chain reaction | CD69 antigen | Cell activation | Lymphocytes | Down-regulation | Peripheral blood
Journal Article
Current Opinion in Immunology, ISSN 0952-7915, 2008, Volume 20, Issue 3, pp. 332 - 338
The successful use of B cell depletion therapy for the treatment of autoimmune disease has led to a resurgent appreciation of B cells as powerful regulators of... 
Allergy and Immunology | ACTIVATION | IFN-GAMMA PRODUCTION | INTERFERON-GAMMA | LUPUS MICE | DISTINCT | CPG-OLIGODEOXYNUCLEOTIDES | CD40 LIGAND | RECEPTOR | IMMUNOLOGY | T-CELLS | IL-10 | Autoimmunity | Models, Immunological | Animals | Humans | B-Lymphocyte Subsets - immunology | Immunologic Memory | Mice | Cytokines - biosynthesis | Cytokines - physiology
Journal Article