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Publication DateHuman molecular genetics, ISSN 0964-6906, 1992
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Somatic cell and molecular genetics, ISSN 0740-7750, 1984
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1998
eJournal
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Loading Rights2004, 3rd ed., ISBN 9780815341840, xxv, 674
Book
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Molecular genetic medicine, ISSN 1057-2805, 1991
Journal
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1999, 2nd ed., ISBN 1859962025, xxiii, 576
Book
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2002, 2nd ed., Cell and molecular biology in action series, ISBN 9780130428110, xiv, 364
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1999, 2nd ed., ISBN 9780471330615, xxiii, 576
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1999, The human molecular genetics series., ISBN 1859961029, xv, 269
Book
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1996, Methods in molecular genetics, ISBN 0120443104, Volume 8, 521
Human Molecular Genetics is a practical guide to the applications of molecular biology and genetics techniques to human cells. A wide range of experimental...
Molecular genetics | Human genetics | Human molecular genetics
Molecular genetics | Human genetics | Human molecular genetics
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Loading Rights1998, Cell and molecular biology in action series, ISBN 9780582322660, xiv, 311
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1995, Human molecular genetics series., ISBN 9781872748092, xviii, 245
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2010, ISBN 9780854900404, xiv, 287
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1971, Series of books in biology, xvi, 650 p. illus., ports.
Book
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2011, 4th ed., ISBN 9780815341499, xxv, 781
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The Journal of Economic Perspectives, ISSN 0895-3309, 10/2011, Volume 25, Issue 4, pp. 57 - 82
The costs of comprehensively genotyping human subjects have fallen to the point where major funding bodies, even in the social sciences, are beginning to...
Genetic markers | Molecular genetics | Genetic variation | Symposium: Genetics and Economics | Medical genetics | Heritability | Genomes | Behavioral genetics | Human genetics | Phenotypic traits | Educational attainment | MONOAMINE-OXIDASE | HUMAN HEIGHT | INDIVIDUAL-DIFFERENCES | RISK-TAKING | The costs of comprehensively genotyping human subjects have fallen to the point where major funding bodies, even in the social sciences, are beginning to incorporate genetic and biological markers into major social surveys. How, if at all, should economists use and combine molecular genetic and economic data from these surveys? What challenges arise when analyzing genetically informative data? To illustrate, we present results from a "genome-wide association study" of educational attainment. We use a sample of 7,500 individuals from the Framingham Heart Study; our dataset contains over 360,000 genetic markers per person. We get some initially promising results linking genetic markers to educational attainment, but these fail to replicate in a second large sample of 9,500 people from the Rotterdam Study. Unfortunately such failure is typical in molecular genetic studies of this type, so the example is also cautionary. We discuss a number of methodological challenges that face researchers who use molecular genetics to reliably identify genetic associates of economic traits. Our overall assessment is cautiously optimistic: this new data source has potential in economics. But researchers and consumers of the genoeconomic literature should be wary of the pitfalls, most notably the difficulty of doing reliable inference when faced with multiple hypothesis problems on a scale never before encountered in social science | DETERMINANTS | BEHAVIOR | MISSING HERITABILITY | ECONOMICS | DICTATOR GAME | STRATIFICATION | GENOME-WIDE ASSOCIATION | Usage | Research | Behavioral economics | Analysis | Studies | Biomarkers | Genetics | Economic theory
Genetic markers | Molecular genetics | Genetic variation | Symposium: Genetics and Economics | Medical genetics | Heritability | Genomes | Behavioral genetics | Human genetics | Phenotypic traits | Educational attainment | MONOAMINE-OXIDASE | HUMAN HEIGHT | INDIVIDUAL-DIFFERENCES | RISK-TAKING | The costs of comprehensively genotyping human subjects have fallen to the point where major funding bodies, even in the social sciences, are beginning to incorporate genetic and biological markers into major social surveys. How, if at all, should economists use and combine molecular genetic and economic data from these surveys? What challenges arise when analyzing genetically informative data? To illustrate, we present results from a "genome-wide association study" of educational attainment. We use a sample of 7,500 individuals from the Framingham Heart Study; our dataset contains over 360,000 genetic markers per person. We get some initially promising results linking genetic markers to educational attainment, but these fail to replicate in a second large sample of 9,500 people from the Rotterdam Study. Unfortunately such failure is typical in molecular genetic studies of this type, so the example is also cautionary. We discuss a number of methodological challenges that face researchers who use molecular genetics to reliably identify genetic associates of economic traits. Our overall assessment is cautiously optimistic: this new data source has potential in economics. But researchers and consumers of the genoeconomic literature should be wary of the pitfalls, most notably the difficulty of doing reliable inference when faced with multiple hypothesis problems on a scale never before encountered in social science | DETERMINANTS | BEHAVIOR | MISSING HERITABILITY | ECONOMICS | DICTATOR GAME | STRATIFICATION | GENOME-WIDE ASSOCIATION | Usage | Research | Behavioral economics | Analysis | Studies | Biomarkers | Genetics | Economic theory
Journal Article
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Loading Rights2005, 2nd ed., ISBN 0471474266, 660
Dr. Jack J. Pasternak received his Ph.D. from Indiana University and is now Professor Emeritus at the University of Waterloo. He has authored or co-authored...
Human molecular genetics | Genetic disorders
Human molecular genetics | Genetic disorders
eBook
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Loading Rights2005, 1st ed., ISBN 354022985X, xvi, 392
Lung cancer is the leading cause of cancer mortality in Western countries. It also provides an archetypal example of how inherited predisposing genetic...
Lungs | Clinical & internal medicine | Human genetics | Human Genetics | Cancer Research | Oncology | Biomedicine
Lungs | Clinical & internal medicine | Human genetics | Human Genetics | Cancer Research | Oncology | Biomedicine
Book
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1997, ISBN 0412589702, xii, 480
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