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Virology, ISSN 0042-6822, 2012, Volume 435, Issue 1, pp. 14 - 28
Abstract Work with human specific viruses will greatly benefit from the use of an in vivo system that provides human target cells and tissues in a... 
Infectious Disease | HIV-1 in humanized mice | HIV-1 vaginal and rectal mucosal transmission | Drug testing in humanized mice | Gene therapy in humanized mice | HIV therapies and prevention using humanized mice | Antibody responses in humanized mice | Immune responses in humanized mice | Monoclonal antibodies in humanized mice | T cell responses in humanized mice | Dengue, HCV, and EBV in humanized mice | Novel siRNA and aptamer therapies in humanized mice | Comparisons of humanized mice | HIV-1 latency in humanized mice | PROGRESSIVE HIV-1 INFECTION | transmission Novel siRNA and aptamer therapies in | HIV-1 vaginal and rectal mucosal | HUMAN-IMMUNODEFICIENCY-VIRUS | NSG-BLT MICE | REGULATORY PROTEIN ALPHA | T-CELL RESPONSES | VIROLOGY | HEMATOPOIETIC STEM-CELLS | HIV therapies and prevention using | HUMAN IMMUNE-SYSTEM | EPSTEIN-BARR-VIRUS | humanized mice | SCID IL2R-GAMMA(NULL) MICE | RAG-HU MICE | Immunoglobulins | Virus Diseases - immunology | Humans | HLA Antigens - immunology | Hematopoietic Stem Cell Transplantation | Transplantation, Heterologous | Virus Diseases - virology | Viruses - immunology | HLA Antigens - genetics | Mice, Transgenic - immunology | T-Lymphocytes - virology | Thymus Gland - virology | Founder Effect | Animals | T-Lymphocytes - immunology | Thymus Gland - immunology | Mice | Liver Transplantation - immunology | Mice, Transgenic - virology | Immunoglobulin Class Switching | Disease Models, Animal | Antiviral agents | Biological products | Immunoglobulin G | Transplantation | T cells | HIV (Viruses) | Hematopoietic stem cells | Virus diseases | Disease transmission | Physiological aspects | HIV testing | Monoclonal antibodies | Comparative analysis | Hepatitis C virus | Health aspects | transmission | Novel siRNA and aptamer therapies in
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2013, Volume 369, Issue 8, pp. 711 - 721
Journal Article
Journal Article
Nature, ISSN 0028-0836, 08/2016, Volume 537, Issue 7618, pp. 50 - 56
Journal Article
Journal Article
Nature, ISSN 0028-0836, 05/2017, Volume 545, Issue 7652, pp. 60 - 65
Despite the success of monotherapies based on blockade of programmed cell death 1 (PD-1) in human melanoma, most patients do not experience durable clinical... 
CRITERIA | MELANOMA | PEMBROLIZUMAB | IMMUNE CHECKPOINT BLOCKADE | PD-1 BLOCKADE | MULTIDISCIPLINARY SCIENCES | BRAF INHIBITORS | CHRONIC VIRAL-INFECTION | CANCER-THERAPY | IPILIMUMAB | EXHAUSTION | CD8-Positive T-Lymphocytes - cytology | Antibodies, Monoclonal, Humanized - therapeutic use | Melanoma - blood supply | Humans | Ki-67 Antigen - metabolism | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Treatment Outcome | Melanoma - pathology | Phenotype | Antibodies, Monoclonal, Humanized - administration & dosage | Ki-67 Antigen - immunology | Antibodies, Monoclonal, Humanized - pharmacokinetics | Melanoma - immunology | Melanoma - drug therapy | CD8-Positive T-Lymphocytes - metabolism | Female | Programmed Cell Death 1 Receptor - immunology | Antibodies, Monoclonal, Humanized - immunology | CD8-Positive T-Lymphocytes - immunology | Neoplasm Staging | Tumor Burden - immunology | Oncology, Experimental | Melanoma | Physiological aspects | Research | T cells | Tumors | Apoptosis | Cancer | Profiling | PD-1 protein | CD8 antigen | Medical services | Clinical trials | Lymphocytes T | Blood | Metastases | Immunology | Lymphocytes | Immunotherapy | Peripheral blood | Pretreatment | Medical research | Immunoglobulins | T cell receptors | Pharmacology | Patients | Pathology | Cell death | PD-L1 protein | Infiltration
Journal Article