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Journal of controlled release, ISSN 0168-3659, 2017, Volume 259, pp. 76 - 82
.... Here, we report that hyaluronic acid (HA) coated PLGA nanoparticulate docetaxel (DTX-HPLGA) is particularly robust and can effectively target and suppress orthotopic human lung cancer... 
Coating | PLGA nanoparticles | Nanomedicine | Lung cancer | Docetaxel | DOXORUBICIN | POLYMERIC MICELLES | CHEMISTRY, MULTIDISCIPLINARY | CELLULAR UPTAKE | VITAMIN-E TPGS | BREAST-CANCER | THERAPY | IN-VIVO | PHARMACOLOGY & PHARMACY | CLINICAL TRANSLATION | ANTICANCER DRUG-DELIVERY | PROTEIN DELIVERY | Hyaluronic Acid - therapeutic use | Lung Neoplasms - drug therapy | Drug Carriers - therapeutic use | Nanoparticles - chemistry | Humans | Lung Neoplasms - metabolism | Drug Carriers - administration & dosage | Lung Neoplasms - pathology | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Polyglycolic Acid - therapeutic use | Drug Carriers - chemistry | Lactic Acid - pharmacokinetics | Taxoids - therapeutic use | Nanoparticles - therapeutic use | Antineoplastic Agents - pharmacokinetics | Lactic Acid - administration & dosage | Polyglycolic Acid - administration & dosage | Taxoids - chemistry | A549 Cells | Cell Survival - drug effects | Hyaluronic Acid - administration & dosage | Lactic Acid - chemistry | Hyaluronic Acid - chemistry | Antineoplastic Agents - chemistry | Hyaluronic Acid - pharmacokinetics | Taxoids - pharmacokinetics | Taxoids - administration & dosage | Animals | Polyglycolic Acid - pharmacokinetics | Tumor Burden - drug effects | Mice, Nude | Polyglycolic Acid - chemistry | Cell Line, Tumor | Drug Carriers - pharmacokinetics | Nanoparticles - administration & dosage | Lactic Acid - therapeutic use | Antimitotic agents | Chemotherapy | Antineoplastic agents | Hyaluronic acid | Cancer
Journal Article
Journal of controlled release, ISSN 0168-3659, 2015, Volume 210, pp. 198 - 207
Combinations of topoisomerase inhibitors I and II have been found to synergistically inhibit cancer cell growth in vitro, yet clinical studies of these types... 
Synergistic | Chemotherapy | Drug combinations | Polymer drug conjugate | SINGLE-AGENT CHEMOTHERAPY | CHEMISTRY, MULTIDISCIPLINARY | OVARIAN-CARCINOMA | CELL LUNG-CANCER | HUMAN BREAST-CARCINOMA | ZOLEDRONIC ACID | PHASE-I TRIAL | ENDOTHELIAL-CELLS | IRINOTECAN | PHARMACOLOGY & PHARMACY | PEGYLATED-LIPOSOMAL DOXORUBICIN | CYTOTOXIC AGENTS | Hyaluronic Acid - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Camptothecin - chemistry | Apoptosis - drug effects | Humans | Hyaluronic Acid - chemistry | Topoisomerase I Inhibitors - administration & dosage | Antineoplastic Agents, Phytogenic - chemistry | Topoisomerase II Inhibitors - administration & dosage | Doxorubicin - chemistry | Neoplasms - drug therapy | Drug Synergism | Antineoplastic Agents, Phytogenic - administration & dosage | Animals | Topoisomerase II Inhibitors - chemistry | Tumor Burden - drug effects | Cell Line, Tumor | Camptothecin - administration & dosage | Female | Mice, Inbred BALB C | Neoplasms - pathology | Topoisomerase I Inhibitors - chemistry | Doxorubicin - administration & dosage | Hyaluronic acid | Anthracyclines | Analysis | Medical research | Medicine, Experimental | Drug therapy, Combination | Polymers | Index Medicus | synergistic | polymer drug conjugate | chemotherapy | drug combinations
Journal Article
Biomaterials, ISSN 0142-9612, 2014, Volume 35, Issue 1, pp. 550 - 566
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 06/2016, Volume 232, pp. 93 - 102
... (from day one up to 4weeks) is necessary for an efficient single-administration preventive therapy... 
Perivascular administration | Atorvastatin | Microparticle | Hyaluronic acid hydrogel | Intimal hyperplasia | DRUG-DELIVERY | CASCADE RANDOMIZED-TRIAL | NEOINTIMAL HYPERPLASIA | CHEMISTRY, MULTIDISCIPLINARY | PORCINE MODEL | VENOUS BYPASS | MOUSE CAROTID-ARTERY | STATIN THERAPY | PHARMACOLOGY & PHARMACY | SMOOTH-MUSCLE-CELLS | VEIN GRAFT FAILURE | MOLECULAR-MECHANISMS | Hyaluronic Acid - therapeutic use | Atorvastatin Calcium - administration & dosage | Humans | Hydrogels - pharmacokinetics | Male | Polyglycolic Acid - therapeutic use | Delayed-Action Preparations - administration & dosage | Drug Delivery Systems | Saphenous Vein - metabolism | Tissue Distribution | Lactic Acid - pharmacokinetics | Ligation | Hydrogels - administration & dosage | Delayed-Action Preparations - pharmacokinetics | Hyperplasia - drug therapy | Lactic Acid - administration & dosage | Atorvastatin Calcium - therapeutic use | Polyglycolic Acid - administration & dosage | Atorvastatin Calcium - pharmacokinetics | Hyaluronic Acid - administration & dosage | Mice, Inbred C57BL | Hyaluronic Acid - pharmacokinetics | Animals | Tunica Intima - pathology | Polyglycolic Acid - pharmacokinetics | Delayed-Action Preparations - therapeutic use | Drug Liberation | Carotid Arteries - surgery | Carotid Arteries - pathology | In Vitro Techniques | Lactic Acid - therapeutic use | Hydrogels - therapeutic use | Coronary artery bypass | Hyperplasia | Hyaluronic acid | Product introduction | All terrain vehicles | Medicine, Preventive | Antilipemic agents | Preventive health services | Index Medicus
Journal Article
Journal of controlled release, ISSN 0168-3659, 2017, Volume 267, pp. 191 - 202
.... To improve therapeutic efficacy, polymer drug conjugates carrying synergistic pairs of chemotherapy drugs can be used to reduce drug administration dose... 
Polymer drug conjugates | Synergy | Breast cancer | Drug combinations | Gemcitabine | Doxorubcin | SCHEDULE-DEPENDENT INTERACTION | DRUG | COMBINATION THERAPY | MESOPOROUS SILICA NANOPARTICLES | PHASE-II | ANTITUMOR-ACTIVITY | CHEMISTRY, MULTIDISCIPLINARY | CHEMOTHERAPY | PACLITAXEL | CO-DELIVERY | CISPLATIN | PHARMACOLOGY & PHARMACY | Prodrugs - administration & dosage | Deoxycytidine - chemistry | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - chemistry | Humans | Drug Carriers - administration & dosage | Doxorubicin - chemistry | Prodrugs - chemistry | Triple Negative Breast Neoplasms - drug therapy | Drug Carriers - chemistry | Antimetabolites, Antineoplastic - administration & dosage | Dose-Response Relationship, Drug | Antibiotics, Antineoplastic - chemistry | Doxorubicin - administration & dosage | Cell Survival - drug effects | Hyaluronic Acid - administration & dosage | Deoxycytidine - administration & dosage | Hyaluronic Acid - chemistry | Antimetabolites, Antineoplastic - chemistry | Antibiotics, Antineoplastic - administration & dosage | Drug Synergism | Animals | Cell Line, Tumor | Drug Liberation | Mice | Mice, Inbred BALB C | Deoxycytidine - analogs & derivatives | Drugs | Anthracyclines | Drug delivery systems | Chemotherapy | Analysis | Polymers | Hyaluronic acid | Vehicles | Cancer | Index Medicus
Journal Article
Nanomedicine: Nanotechnology, Biology, and Medicine, ISSN 1549-9634, 2012, Volume 8, Issue 1, pp. 71 - 80
... of anticancer drugs in the body after systemic administration, leading to serious side effects on normal cells.1-4 However, major efforts have recently been made to improve... 
Internal Medicine | Hyaluronan | Ehrlich ascites tumor (EAT) | Antitumor activity | Doxorubicin | Polymersomes | MEDICINE, RESEARCH & EXPERIMENTAL | BLOCK-COPOLYMERS | SOLID TUMORS | DRUG-DELIVERY | RECEPTOR | NANOSCIENCE & NANOTECHNOLOGY | VASCULAR-PERMEABILITY | CANCER | CARRIERS | PACLITAXEL | LIPOSOMAL DOXORUBICIN | ENDOCYTOSIS HARE | Doxorubicin - blood | Doxorubicin - therapeutic use | Drug Carriers - adverse effects | Hyaluronic Acid - therapeutic use | Nanoparticles - chemistry | Antineoplastic Agents - chemical synthesis | Humans | Drug Carriers - administration & dosage | Polyglutamic Acid - administration & dosage | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Nanoparticles - adverse effects | Drug Carriers - chemistry | Polyglutamic Acid - analogs & derivatives | Antineoplastic Agents - adverse effects | Female | Hyaluronic Acid - blood | Hyaluronic Acid - adverse effects | Doxorubicin - administration & dosage | Endocytosis - immunology | Technetium - chemistry | Rabbits | Hyaluronic Acid - administration & dosage | Hyaluronic Acid - chemistry | Carcinoma, Ehrlich Tumor - drug therapy | Doxorubicin - chemical synthesis | Polyglutamic Acid - blood | Polyglutamic Acid - chemistry | Animals | Hyaluronic Acid - analogs & derivatives | Antineoplastic Agents - blood | Hyaluronan Receptors - immunology | Mice | Mice, Inbred BALB C | Nanoparticles - administration & dosage | Polyglutamic Acid - therapeutic use | Neoplasms, Experimental - drug therapy | Doxorubicin - adverse effects | Polyglutamic Acid - adverse effects | Anthracyclines | Ascites | Hyaluronic acid | Tumors | Polymers | Chemical Sciences
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 7/2011, Volume 68, Issue 1, pp. 107 - 116