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Nature (London), ISSN 1476-4687, 2011, Volume 471, Issue 7336, pp. 119 - 123
Misrepair of DNA double-strand breaks produced by the V(D)J recombinase (the RAG1/RAG2 proteins) at immunoglobulin (Ig) and T cell receptor (Tcr) loci has been... 
THYMIC LYMPHOMA | REPAIR | LYMPHOCYTE DEVELOPMENT | B-CELL | ROLES | TRANSLOCATIONS | MULTIDISCIPLINARY SCIENCES | V(D)J RECOMBINATION | DOUBLE-STRAND BREAKS | GENE AMPLIFICATION | ATM-DEFICIENT MICE | Genomic Instability | Protein-Serine-Threonine Kinases - deficiency | Gene Rearrangement, T-Lymphocyte - genetics | Chromosomes, Mammalian - genetics | DNA-Binding Proteins - deficiency | DNA-Binding Proteins - metabolism | Tumor Suppressor Proteins - deficiency | Tumor Suppressor Proteins - chemistry | Tumor Suppressor Proteins - genetics | Cell Cycle Proteins - genetics | Recombination, Genetic - genetics | Lymphoma - pathology | Chromosome Deletion | Tumor Suppressor Proteins - metabolism | Kaplan-Meier Estimate | Protein-Serine-Threonine Kinases - genetics | Thymus Gland - cytology | Lymphoma - genetics | In Situ Hybridization, Fluorescence | Ataxia Telangiectasia Mutated Proteins | Genes, p53 - genetics | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | Disease Progression | Animals | Genes, Immunoglobulin Heavy Chain - genetics | Mice | Receptors, Antigen, T-Cell - genetics | Translocation, Genetic - genetics | Causes of | Tumor suppressor genes | Lymphomas | Genetic aspects | Abnormalities | Software | Chromosomes | Deoxyribonucleic acid--DNA | Cell cycle | Apoptosis | Tumors | Thymus Gland | Translocation, Genetic | Protein-Serine-Threonine Kinases | Gene Rearrangement, T-Lymphocyte | Receptors, Antigen, T-Cell | Lymphoma | Chromosomes, Mammalian | Genes, Immunoglobulin Heavy Chain | Life Sciences | Genes, p53 | Immunology | Recombination, Genetic | Cell Cycle Proteins | Tumor Suppressor Proteins | DNA-Binding Proteins
Journal Article
by Amps, Katherine and Andrews, Peter W and Anyfantis, George and Armstrong, Lyle and Avery, Stuart and Baharvand, Hossein and Baker, Julie and Baker, Duncan and Munoz, Maria B and Beil, Stephen and Benvenisty, Nissim and Ben-Yosef, Dalit and Biancotti, Juan-Carlos and Bosman, Alexis and Brena, Romulo Martin and Brison, Daniel and Caisander, Gunilla and Camarasa, Marãa V and Chen, Jieming and Chiao, Eric and Choi, Young Min and Choo, Andre B. H and Collins, Daniel and Colman, Alan and Crook, Jeremy M and Daley, George Q and Dalton, Anne and De Sousa, Paul A and Denning, Chris and Downie, Janet and Dvorak, Petr and Montgomery, Karen D and Feki, Anis and Ford, Angela and Fox, Victoria and Fraga, Ana M and Frumkin, Tzvia and Ge, Lin and Gokhale, Paul J and Golan-Lev, Tamar and Gourabi, Hamid and Gropp, Michal and Guangxiu, Lu and Hampl, Ales and Harron, Katie and Healy, Lyn and Herath, Wishva and Holm, Frida and Hovatta, Outi and Hyllner, Johan and Inamdar, Maneesha S and Irwanto, Astrid Kresentia and Ishii, Tetsuya and Jaconi, Marisa and Jin, Ying and Kimber, Susan and Kiselev, Sergey and Knowles, Barbara B and Kopper, Oded and Kukharenko, Valeri and Kuliev, Anver and Lagarkova, Maria A and Laird, Peter W and Lako, Majlinda and Laslett, Andrew L and Lavon, Neta and Lee, Dong Ryul and Lee, Jeoung Eun and Li, Chunliang and Lim, Linda S and Ludwig, Tenneille E and Ma, Yu and Maltby, Edna and Mateizel, Ileana and Mayshar, Yoav and Mileikovsky, Maria and Minger, Stephen L and Miyazaki, Takamichi and Moon, Shin Yong and Moore, Harry and Mummery, Christine and Nagy, Andras and Nakatsuji, Norio and Narwani, Kavita and Oh, Steve K. W and Oh, Sun Kyung and Olson, Cia and Otonkoski, Timo and Pan, Fei and Park, In-Hyun and Pells, Steve and Pera, Martin F and Pereira, Lygia V and Qi, Ouyang and Raj, Grace Selva and Reubinoff, Benjamin and Robins, Alan and Robson, Paul and Rossant, Janet and Salekdeh, Ghasem H and ... and The International Stem Cell Initiative and Int Stem Cell Initiative and International Stem Cell Initiative
Nature biotechnology, ISSN 1546-1696, 2011, Volume 29, Issue 12, pp. 1132 - 1144
Journal Article
American journal of human genetics, ISSN 0002-9297, 2015, Volume 96, Issue 4, pp. 597 - 611
Esophageal squamous cell carcinoma (ESCC) is one of the most common cancers worldwide and the fourth most lethal cancer in China. However, although genomic... 
POPULATION | DNA | SUSCEPTIBILITY | GENETICS & HEREDITY | ARCHITECTURE | WIDE ASSOCIATION | DIFFERENTIATION | IDENTIFICATION | SOMATIC MUTATIONS | HUMAN CANCER | BREAST | Immunohistochemistry | Carcinoma, Squamous Cell - genetics | Humans | Molecular Sequence Data | Immunoblotting | Gene Knockdown Techniques | CREB-Binding Protein - genetics | Polycomb Repressive Complex 1 - genetics | Tetrazolium Salts | APOBEC-1 Deaminase | Ligases | Base Sequence | China | Tumor Suppressor Proteins - genetics | Thiazoles | Patched Receptors | Real-Time Polymerase Chain Reaction | Esophageal Squamous Cell Carcinoma | Genetic Predisposition to Disease - genetics | Cytidine Deaminase - genetics | In Situ Hybridization, Fluorescence | DNA Copy Number Variations - genetics | Signal Transduction - genetics | Transcription Factors - genetics | Mutation - genetics | Ubiquitin Thiolesterase - genetics | Sequence Analysis, DNA | Genome, Human - genetics | Phosphatidylinositol 3-Kinases - genetics | Class I Phosphatidylinositol 3-Kinases | Analysis of Variance | Esophageal Neoplasms - genetics | Polycomb-Group Proteins - genetics | Cell Line, Tumor | LIM Domain Proteins - genetics | Ubiquitin-Protein Ligases - genetics | Patched-1 Receptor | Receptors, Cell Surface - genetics | Squamous cell carcinoma | Genetic aspects | Gene mutations | Identification and classification | Esophageal cancer
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 10/2014, Volume 111, Issue 43, pp. 15497 - 15501
Journal Article
Journal Article
Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 5110 - 13
Non-small cell lung carcinoma (NSCLC) is leading cause of cancer-related deaths in the world. The Tumor Suppressor Candidate 3 (TUSC3) at chromosome 8p22 known... 
CELL LUNG-CANCER | GLUCOSE-REGULATED PROTEINS | FREQUENT ALLELIC LOSS | HOMOZYGOUS DELETION | OXIDOREDUCTASE ACTIVITY | TUMOR PROGRESSION | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | ENDOPLASMIC-RETICULUM STRESS | OVARIAN-CANCER | MESENCHYMAL TRANSITION | Endoribonucleases - genetics | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | MicroRNAs - metabolism | Activating Transcription Factor 6 - genetics | Tumor Suppressor Protein p53 - genetics | In Situ Hybridization | Tumor Suppressor Proteins - genetics | Membrane Proteins - metabolism | Gene Expression Regulation, Neoplastic - physiology | Gene Expression Regulation, Neoplastic - genetics | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Cell Proliferation - genetics | Tumor Suppressor Proteins - metabolism | Endoribonucleases - metabolism | Unfolded Protein Response - genetics | Carcinoma, Non-Small-Cell Lung - genetics | Membrane Proteins - genetics | Endoplasmic Reticulum-Associated Degradation - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Cell Proliferation - physiology | Tumor Suppressor Protein p53 - metabolism | Ubiquitin-Protein Ligases - metabolism | Signal Transduction - genetics | Reverse Transcriptase Polymerase Chain Reaction | Xenograft Model Antitumor Assays | Activating Transcription Factor 6 - metabolism | Animals | Endoplasmic Reticulum-Associated Degradation - physiology | Cell Line, Tumor | Signal Transduction - physiology | Mice | Ubiquitin-Protein Ligases - genetics | Unfolded Protein Response - physiology | Small cell lung carcinoma | p53 Protein | Lung cancer | Non-small cell lung carcinoma | Lung carcinoma | Metastasis | Substrates | Metastases | Proteins | Protein folding | Chromosome 8 | Tumor suppressor genes | miRNA | Solid tumors | Tumors | Cancer
Journal Article
by Jacquemont, Sébastien and Reymond, Alexandre and Zufferey, Flore and Harewood, Louise and Walters, Robin G and Kutalik, Zoltán and Martinet, Danielle and Shen, Yiping and Valsesia, Armand and Beckmann, Noam D and Thorleifsson, Gudmar and Belfiore, Marco and Bouquillon, Sonia and Campion, Dominique and de Leeuw, Nicole and de Vries, Bert B. A and Esko, Tõnu and Fernandez, Bridget A and Fernández-Aranda, Fernando and Fernández-Real, José Manuel and Gratacòs, Mònica and Guilmatre, Audrey and Hoyer, Juliane and Jarvelin, Marjo-Riitta and Frank Kooy, R and Kurg, Ants and Le Caignec, Cédric and Männik, Katrin and Platt, Orah S and Sanlaville, Damien and Van Haelst, Mieke M and Villatoro Gomez, Sergi and Walha, Faida and Wu, Bai-lin and Yu, Yongguo and Aboura, Azzedine and Addor, Marie-Claude and Alembik, Yves and Antonarakis, Stylianos E and Arveiler, Benoît and Barth, Magalie and Bednarek, Nathalie and Béna, Frédérique and Bergmann, Sven and Beri, Mylène and Bernardini, Laura and Blaumeiser, Bettina and Bonneau, Dominique and Bottani, Armand and Boute, Odile and Brunner, Han G and Cailley, Dorothée and Callier, Patrick and Chiesa, Jean and Chrast, Jacqueline and Coin, Lachlan and Coutton, Charles and Cuisset, Jean-Marie and Cuvellier, Jean-Christophe and David, Albert and de Freminville, Bénédicte and Delobel, Bruno and Delrue, Marie-Ange and Demeer, Bénédicte and Descamps, Dominique and Didelot, Gérard and Dieterich, Klaus and Disciglio, Vittoria and Doco-Fenzy, Martine and Drunat, Séverine and Duban-Bedu, Bénédicte and Dubourg, Christèle and El-Sayed Moustafa, Julia S and Elliott, Paul and Faas, Brigitte H. W and Faivre, Laurence and Faudet, Anne and Fellmann, Florence and Ferrarini, Alessandra and Fisher, Richard and Flori, Elisabeth and Forer, Lukas and Gaillard, Dominique and Gerard, Marion and Gieger, Christian and Gimelli, Stefania and Gimelli, Giorgio and Grabe, Hans J and Guichet, Agnès and Guillin, Olivier and Hartikainen, Anna-Liisa and Heron, Délphine and Hippolyte, Loyse and Holder, Muriel and Homuth, Georg and Isidor, Bertrand and Jaillard, Sylvie and Jaros, Zdenek and Jiménez-Murcia, Susana and Joly Helas, Géraldine and ...
Nature (London), ISSN 1476-4687, 2011, Volume 478, Issue 7367, pp. 97 - 102
.... In contrast to obesity, few genetic variants underlying these clinical conditions have been reported... 
DEPENDENT PROBE AMPLIFICATION | FAILURE-TO-THRIVE | METABOLIC SYNDROME | RELATIVE QUANTIFICATION | SNP GENOTYPING DATA | HIDDEN-MARKOV MODEL | MULTIDISCIPLINARY SCIENCES | BODY-MASS INDEX | TIME QUANTITATIVE PCR | COPY NUMBER VARIATION | CIRCULAR BINARY SEGMENTATION | Humans | Middle Aged | Child, Preschool | RNA, Messenger - analysis | Head - anatomy & histology | Infant | Male | Developmental Disabilities - genetics | Gene Expression Profiling | North America | Obesity - genetics | Case-Control Studies | Young Adult | Mental Disorders - genetics | Aging | Gene Duplication - genetics | Adult | Female | Transcription, Genetic | Energy Metabolism - genetics | Child | Infant, Newborn | Chromosomes, Human, Pair 16 - genetics | Body Mass Index | Gene Dosage - genetics | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Europe | RNA, Messenger - genetics | Mutation - genetics | Body Height - genetics | Thinness - genetics | Phenotype | Comparative Genomic Hybridization | Adolescent | Heterozygote | Aged | Cohort Studies | Sequence Deletion - genetics | Obesity | Chromosome mapping | Usage | Genetic variation | Genetic aspects | Cognition disorders | Research | Risk factors | Schizophrenia | Gender | Behavior | Gene expression | Bias | Life Sciences | Human health and pathology | Genetics | Endocrinology and metabolism | Gene Duplication | Developmental Disabilities | Sequence Deletion | Thinness | genetics | Genetic Predisposition to Disease | Head | Gene Dosage | analysis | Energy Metabolism | Mental Disorders | Chromosomes, Human, Pair 16 | Body Height | Mutation | anatomy & histology | RNA, Messenger
Journal Article
Journal of dental research, ISSN 1544-0591, 2012, Volume 91, Issue 7_suppl, pp. S21 - S28
.... To date, there is limited evidence on host genetic risk loci associated with periodontal pathogen colonization... 
infection | genetics | bacteria | dentistry | genome-wide association studies | chronic periodontitis | VISUALIZATION | ADULTS | RISK | MICROBIOTA | HEALTH