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1. Full Text Comparative Analysis of Four Oxidized Guanine Lesions from Reactions of DNA with Peroxynitrite, Singlet Oxygen, and γ‑Radiation
by Cui, Liang and Ye, Wenjie and Prestwich, Erin G and Wishnok, John S and Taghizadeh, Koli and Dedon, Peter C and Tannenbaum, Steven R
Chemical research in toxicology, ISSN 0893-228X, 02/2013, Volume 26, Issue 2, pp. 195 - 202
Physical Sciences | Toxicology | Chemistry | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Chemistry, Multidisciplinary | Science & Technology | Guanosine - analogs & derivatives | Gamma Rays | Oxidants - chemistry | Oxidation-Reduction | Oxidants - toxicity | Peroxynitrous Acid - toxicity | Deoxyguanosine - chemistry | Guanidines - chemistry | DNA - chemistry | Rose Bengal - chemistry | Singlet Oxygen - toxicity | Animals | Guanosine - chemistry | Singlet Oxygen - chemistry | Cattle | Guanine - chemistry | Rose Bengal - toxicity | Peroxynitrous Acid - chemistry | Hydantoins - chemistry | Deoxyguanosine - analogs & derivatives | Spiro Compounds - chemistry | Index Medicus
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2. Full Text 5‑Carboxamido-5-formamido-2-iminohydantoin, in Addition to 8‑oxo-7,8-Dihydroguanine, Is the Major Product of the Iron-Fenton or X‑ray Radiation-Induced Oxidation of Guanine under Aerobic Reducing Conditions in Nucleoside and DNA Contexts
by Alshykhly, Omar R and Fleming, Aaron M and Burrows, Cynthia J
Journal of organic chemistry, ISSN 0022-3263, 07/2015, Volume 80, Issue 14, pp. 6996 - 7007
Physical Sciences | Chemistry | Chemistry, Organic | Science & Technology | Nucleosides - chemistry | Oxidation-Reduction | Guanine - analogs & derivatives | Iron - chemistry | Oxazolone - chemistry | Deoxyguanosine - chemistry | Guanidines - chemistry | DNA - chemistry | X-Rays | Oxygen - chemistry | Guanine - chemistry | Molecular Structure | Hydantoins - chemistry | Deoxyguanosine - analogs & derivatives | Amidines | Oxidation-reduction reaction | Radiolysis | Deoxyribonucleotides | Chemical properties | Research | Index Medicus
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3. Full Text Ugi Reactions with CO2: Access to Functionalized Polyurethanes, Polycarbonates, Polyamides, and Polyhydantoins
by Sehlinger, Ansgar and Schneider, Rebekka and Meier, Michael A. R
Macromolecular rapid communications., ISSN 1022-1336, 11/2014, Volume 35, Issue 21, pp. 1866 - 1871
carbon dioxide | multicomponent reactions | poly­hydantoins | Ugi five‐component condensation | polyurethanes | polyhydantoins | Ugi five-component condensation | Polymer Science | Physical Sciences | Science & Technology | Applied sciences | Organic polymers | Physicochemistry of polymers | Preparation, kinetics, thermodynamics, mechanism and catalysts | Polycondensation | Exact sciences and technology | Amines - chemistry | Alcohols - chemistry | Carbon Dioxide - chemistry | Models, Chemical | Polycarboxylate Cement - chemistry | Polymers - chemical synthesis | Polyurethanes - chemistry | Nylons - chemistry | Polymerization | Cyanides - chemistry | Diamines - chemistry | Polymers - chemistry | Hexanes - chemistry | Molecular Structure | Hydantoins - chemistry | Aldehydes - chemistry | Multicomponent reactions | Poly-hydantoins | Polyurethanes | Carbon dioxide | Polyamides | Polycarbonates | Index Medicus
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4. Full Text Antitussive and Anti-inflammatory Dual-active Agents Developed from Natural Product Lead Compound 1-Methylhydantoin
by Xu, Yang and Wang, Fang and Guo, Hongye and Wang, Shihan and Ni, Shuling and Zhou, Yan and Wang, Zhihan and Bao, Huiwei and Wang, Yongsheng
Molecules (Basel, Switzerland), ISSN 1420-3049, 07/2019, Volume 24, Issue 13, p. 2355
Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Drugs, Chinese Herbal - pharmacology | Biological Products - pharmacology | Structure-Activity Relationship | Antitussive Agents - pharmacology | Drug Design | Cyclooxygenase 1 - chemistry | Molecular Structure | Drugs, Chinese Herbal - chemical synthesis | Hydantoins - chemical synthesis | Antitussive Agents - chemical synthesis | Hydantoins - pharmacology | Anti-Inflammatory Agents - pharmacology | Cyclooxygenase 2 - chemistry | Molecular Dynamics Simulation | Antitussive Agents - chemistry | Biological Products - chemistry | Animals | Anti-Inflammatory Agents - chemistry | Drugs, Chinese Herbal - chemistry | Cyclooxygenase 2 - metabolism | Protein Binding | Anti-Inflammatory Agents - chemical synthesis | Mice | Molecular Docking Simulation | Cyclooxygenase 1 - metabolism | Hydantoins - chemistry | Index Medicus | Oviductus Ranae | 1-methylhydantoin | natural product | anti-inflammatory | dual-active | antitussive | acute pneumonia
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5. Full Text Privileged Scaffolds or Promiscuous Binders: A Comparative Study on Rhodanines and Related Heterocycles in Medicinal Chemistry
by Mendgen, Thomas and Steuer, Christian and Klein, Christian D
Journal of medicinal chemistry, ISSN 0022-2623, 01/2012, Volume 55, Issue 2, pp. 743 - 753
Rhodanine - chemical synthesis | Rhodanine - chemistry | Stereoisomerism | Models, Molecular | Transferases - chemistry | Crystallography, X-Ray | Structure-Activity Relationship | Thiazolidinediones - chemistry | Enzyme Inhibitors - chemical synthesis | Hydrogen Bonding | Rhodanine - analogs & derivatives | Thiazolidinediones - chemical synthesis | Enzyme Inhibitors - chemistry | Protein Binding | Ligands | Serine Proteases - chemistry | Molecular Structure | Hydantoins - chemistry | Binding Sites | Metalloproteases - chemistry | Hydantoins - chemical synthesis | Index Medicus
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6. Full Text Synthesis of Carbocyclic Hydantocidins via Regioselective and Diastereoselective Phosphine-Catalyzed [3 + 2]-Cycloadditions to 5-Methylenehydantoins
by Pham, Tien Q and Pyne, Stephen G and Skelton, Brian W and White, Allan H and Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Journal of organic chemistry, ISSN 0022-3263, 08/2005, Volume 70, Issue 16, pp. 6369 - 6377
Organic chemistry | Chemistry | Heterocyclic compounds | Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings | Preparations and properties | Exact sciences and technology | Phosphines - chemistry | Cyclization | Stereoisomerism | Butyrates - chemistry | Biological Factors - chemistry | Molecular Structure | Catalysis | Hydantoins - chemistry | Methylation | Biological Factors - chemical synthesis | Carbon - chemistry | Hydantoins - chemical synthesis | Carbocyclic compounds | Chemical properties | Ring formation (Chemistry) | Chemical synthesis | Analysis | Index Medicus | INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY | SYNTHESIS | CHEMISTRY | CAMPHOR
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7. Full Text Computer-aided studies for novel arylhydantoin 1,3,5-triazine derivatives as 5-HT6 serotonin receptor ligands with antidepressive-like, anxiolytic and antiobesity action in vivo
by Kurczab, Rafal and Ali, Wesam and Łazewska, Dorota and Kotánska, Magdalena and Jastrzebska-Wiesek, Magdalena and Satała, Grzegorz and Wiecek, Małgorzata and Lubelska, Annamaria and Latacz, Gniewomir and Partyka, Anna and Starek, Małgorzata and Dabrowska, Monika and Wesołowska, Anna and Jacob, Claus and Kiéc-Kononowicz, Katarzyna and Handzlik, Jadwiga
Molecules (Basel, Switzerland), ISSN 1420-3049, 10/2018, Volume 23, Issue 10, p. 2529
ligands | Obesity | ADMET in vitro | Serotonin receptors | Hydantoin | Docking | 1,3,5-triazine | 5-HT | Antidepressive | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Triazines - therapeutic use | Humans | Serotonin - chemistry | Structure-Activity Relationship | Receptors, Serotonin - chemistry | Anti-Obesity Agents - therapeutic use | Antidepressive Agents - therapeutic use | Anti-Obesity Agents - chemistry | Animals | Antidepressive Agents - chemistry | Serotonin - metabolism | Triazines - chemical synthesis | Anti-Anxiety Agents - chemistry | Ligands | Triazines - chemistry | Molecular Structure | Anti-Anxiety Agents - therapeutic use | Hydantoins - chemistry | Index Medicus | docking | serotonin receptors | hydantoin | antidepressive | 5-HT6 ligands | obesity
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8. Full Text Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter
by Simone Weyand and Tatsuro Shimamura and Shunsuke Yajima and Shun'ichi Suzuki and Osman Mirza and Kuakarun Krusong and Elisabeth P. Carpenter and Nicholas G. Rutherford and Jonathan M. Hadden and John O'Reilly and Pikyee Ma and Massoud Saidijam and Simon G. Patching and Ryan J. Hope and Halina T. Norbertczak and Peter C. J. Roach and So Iwata and Peter J. F. Henderson and Alexander D. Cameron
Science (American Association for the Advancement of Science), ISSN 0036-8075, 10/2008, Volume 322, Issue 5902, pp. 709 - 713
Membrane transport proteins | String theory | Sodium | Molecular structure | Amino acids | Research Articles | Grants | Electron density | Hydantoins | Binding sites | P branes | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Structure in molecular biology | Molecular biophysics | Crystalline structure | Amino Acid Sequence | Cations - chemistry | Protein Structure, Secondary | Cations - metabolism | Bacterial Proteins - chemistry | Models, Molecular | Molecular Sequence Data | Crystallography, X-Ray | Sodium - metabolism | Symporters - chemistry | Nucleobase Transport Proteins - chemistry | Symporters - metabolism | Actinomycetales - metabolism | Cell Membrane - chemistry | Nucleobase Transport Proteins - metabolism | Actinomycetales - chemistry | Bacterial Proteins - metabolism | Protein Conformation | Cell Membrane - metabolism | Ion Transport | Hydantoins - chemistry | Binding Sites | Hydantoins - metabolism | Actinomycetales | Evaluation | Substrates (Biochemistry) | Properties | Biological transport | Bacteria | Molecular biology | Substrates | Index Medicus | Life Sciences | Cristallography | Chemical Sciences | Radiochemistry
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9. Full Text A Possible Primordial Peptide Cycle
by Claudia Huber and Wolfgang Eisenreich and Stefan Hecht and Günter Wächtershäuser
Science (American Association for the Advancement of Science), ISSN 0036-8075, 8/2003, Volume 301, Issue 5635, pp. 938 - 940
Anhydrides | Oxygen | Materials | Atoms | Amino acids | Anabolics | Materials science | Reports | Laser beams | Hydantoins | Molecular weight | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Proteins | Chemistry | Analytical, structural and metabolic biochemistry | Inorganic chemistry and origins of life | Origins of life | Aminoacids, peptides. Hormones. Neuropeptides | Exact sciences and technology | Biological and medical sciences | Carbon Dioxide - chemistry | Stereoisomerism | Amino Acids - chemistry | Carbon Monoxide - chemistry | Chromatography, High Pressure Liquid | Origin of Life | Carbon Monoxide - metabolism | Urea - chemistry | Urease - chemistry | Amino Acids - metabolism | Peptides - metabolism | Phenylalanine - chemistry | Mass Spectrometry | Urea - metabolism | Ferrous Compounds - chemistry | Dipeptides - metabolism | Evolution, Chemical | Carbon Dioxide - metabolism | Phenylalanine - metabolism | Nickel - chemistry | Oxidation-Reduction | Peptides - chemistry | Hot Temperature | Dipeptides - chemistry | Pressure | Hydrolysis | Ferrous Compounds - metabolism | Urease - metabolism | Nickel - metabolism | Hydrogen-Ion Concentration | Enzymes | Hydrolases | Research | Carbon monoxide | Peptides | Metabolism | Index Medicus
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10. Full Text Reverse Transcription Past Products of Guanine Oxidation in RNA Leads to Insertion of A and C opposite 8‑Oxo-7,8-dihydroguanine and A and G opposite 5‑Guanidinohydantoin and Spiroiminodihydantoin Diastereomers
by Alenko, Anton and Fleming, Aaron M and Burrows, Cynthia J
Biochemistry (Easton), ISSN 0006-2960, 09/2017, Volume 56, Issue 38, pp. 5053 - 5064
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Guanosine - analogs & derivatives | Oxidation-Reduction | RNA-Directed DNA Polymerase - metabolism | Guanine - analogs & derivatives | Stereoisomerism | Guanosine - genetics | RNA - chemistry | Adenine - chemistry | Reverse Transcription | Guanidines - chemistry | Guanosine - chemistry | RNA-Directed DNA Polymerase - chemistry | Guanine - chemistry | Kinetics | Hydantoins - chemistry | Spiro Compounds - chemistry | Usage | RNA | Gene mutations | Chemical reactions | Research | Chemical properties | Guanine | Index Medicus | RNA sequencing | Reverse transcription | Oxidative damage | Guanidinohydantoin | Spiroiminodihydantoin | 8-Oxo-7, 8-dihydroguanine
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11. Full Text Antimicrobial N-halamine modified chitosan films
by Li, Rong and Hu, Pei and Ren, Xuehong and Worley, S.D and Huang, T.S
Carbohydrate polymers, ISSN 0144-8617, 01/2013, Volume 92, Issue 1, pp. 534 - 539
Chitosan | Antibacterial | Biocidal | N-halamine | Films | Physical Sciences | Chemistry | Chemistry, Organic | Polymer Science | Chemistry, Applied | Science & Technology | Applied sciences | Physicochemistry of polymers | Natural polymers | Starch and polysaccharides | Exact sciences and technology | Hydantoins - pharmacology | Polymers - chemical synthesis | Coated Materials, Biocompatible | Anti-Bacterial Agents - chemical synthesis | Chitosan - chemistry | Anti-Bacterial Agents - chemistry | Escherichia coli O157 - drug effects | Polymers - pharmacology | Chitosan - pharmacology | Polymers - chemistry | Anti-Bacterial Agents - pharmacology | Hydantoins - chemistry | Staphylococcus aureus - drug effects | Chitosan - chemical synthesis | Hydantoins - chemical synthesis | Index Medicus
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12. Full Text Recent applications of hydantoin and thiohydantoin in medicinal chemistry
by Cho, SeoHyun and Kim, Seok-Ho and Shin, Dongyun
European journal of medicinal chemistry, ISSN 0223-5234, 02/2019, Volume 164, pp. 517 - 545
Imidazolidine-2,4-dione | Medicinal chemistry | Heterocycle | Thiohydantoin | Hydantoin | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Index Medicus
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