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1. Full Text Inotropic agents and vasodilator strategies for the treatment of cardiogenic shock or low cardiac output syndrome
by Schumann, Julia and Henrich, Eva C and Strobl, Hellen and Prondzinsky, Roland and Weiche, Sophie and Thiele, Holger and Werdan, Karl and Frantz, Stefan and Unverzagt, Susanne and Schumann, Julia
Cochrane Database of Systematic Reviews, ISSN 1469-493X, 01/2018, Volume 2018, Issue 1, pp. CD009669 - CD009669
Simendan | C.1 Drugs | Dobutamine | Hydrazones | Nitric Oxide | Cardiac Output, Low | Cause of Death | Randomized Controlled Trials as Topic | Cardiotonic Agents | Pyridazines | Vasodilator Agents | Myocardial ischemia/coronary disease | Myocardial Infarction | Enoximone | C.1.10 Other | C. Acute Coronary Syndromes/Unstable Angina | Shock, Cardiogenic | Heart & circulation | Medicine General & Introductory Medical Sciences | Acute coronary syndrome | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Myocardial Infarction - mortality | Vasodilator Agents - therapeutic use | Humans | Middle Aged | Shock, Cardiogenic - mortality | Nitric Oxide - therapeutic use | Cardiac Output, Low - etiology | Cardiotonic Agents - therapeutic use | Myocardial Infarction - complications | Shock, Cardiogenic - drug therapy | Shock, Cardiogenic - etiology | Enoximone - therapeutic use | Cardiac Output, Low - mortality | Hydrazones - therapeutic use | Aged | Cardiac Output, Low - drug therapy | Dobutamine - therapeutic use | Pyridazines - therapeutic use | Index Medicus
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2. Full Text Taxane-Platin-Resistant Lung Cancers Co-develop Hypersensitivity to JumonjiC Demethylase Inhibitors
by Dalvi, Maithili P and Wang, Lei and Zhong, Rui and Kollipara, Rahul K and Park, Hyunsil and Bayo, Juan and Yenerall, Paul and Zhou, Yunyun and Timmons, Brenda C and Rodriguez-Canales, Jaime and Behrens, Carmen and Mino, Barbara and Villalobos, Pamela and Parra, Edwin R and Suraokar, Milind and Pataer, Apar and Swisher, Stephen G and Kalhor, Neda and Bhanu, Natarajan V and Garcia, Benjamin A and Heymach, John V and Coombes, Kevin and Xie, Yang and Girard, Luc and Gazdar, Adi F and Kittler, Ralf and Wistuba, Ignacio I and Minna, John D and Martinez, Elisabeth D
Cell reports (Cambridge), ISSN 2211-1247, 05/2017, Volume 19, Issue 8, pp. 1669 - 1684
lung cancer | histone methylation | taxane-platin chemotherapy | JIB-04 | GSK-J4 | KDM | histone demethylases | demethylase inhibitors | Jumonji demethylases | drug resistance | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Lung Neoplasms - drug therapy | Transcription, Genetic - drug effects | Taxoids - pharmacology | Benzazepines - adverse effects | Humans | Aminopyridines - adverse effects | Lung Neoplasms - pathology | Antineoplastic Agents - therapeutic use | Gene Expression Profiling | Taxoids - therapeutic use | Hydrazones - adverse effects | Aminopyridines - therapeutic use | Carboplatin - therapeutic use | Hydrazones - therapeutic use | Jumonji Domain-Containing Histone Demethylases - antagonists & inhibitors | Bridged-Ring Compounds - pharmacology | Neoadjuvant Therapy | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Bridged-Ring Compounds - therapeutic use | Carcinoma, Non-Small-Cell Lung - genetics | Enzyme Inhibitors - pharmacology | Benzazepines - pharmacology | Pyrimidines - pharmacology | Enzyme Inhibitors - therapeutic use | Hydrazones - pharmacology | Disease-Free Survival | Drug Resistance, Neoplasm - genetics | Animals | Benzazepines - therapeutic use | Pyrimidines - therapeutic use | Aminopyridines - pharmacology | Pyrimidines - adverse effects | Cell Line, Tumor | Mice | Carcinoma, Non-Small-Cell Lung - drug therapy | Histones - metabolism | Carboplatin - pharmacology | Methylation | Jumonji Domain-Containing Histone Demethylases - metabolism | Drug Resistance, Neoplasm - drug effects | Index Medicus
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3. Full Text The effect of vasoactive drugs on mortality in patients with severe sepsis and septic shock. A network meta-analysis of randomized trials
by Belletti, Alessandro, MD and Benedetto, Umberto, MD, PhD and Biondi-Zoccai, Giuseppe, MD and Leggieri, Carlo, MD and Silvani, Paolo, MD and Angelini, Gianni D., MD and Zangrillo, Alberto, MD and Landoni, Giovanni, MD
Journal of critical care, ISSN 0883-9441, 2016, Volume 37, pp. 91 - 98
Critical Care | Microcirculation | Sepsis | Vasopressors | Inotropes | Intensive care | Mortality | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Arginine Vasopressin - therapeutic use | Dopamine - therapeutic use | Vasoconstrictor Agents - therapeutic use | Norepinephrine - therapeutic use | Vasopressins - therapeutic use | Humans | Treatment Outcome | Shock, Septic - mortality | Randomized Controlled Trials as Topic | Sepsis - mortality | Cardiotonic Agents - therapeutic use | Sepsis - drug therapy | Epinephrine - therapeutic use | Hydrazones - therapeutic use | Shock, Septic - drug therapy | Network Meta-Analysis | Odds Ratio | Dobutamine - therapeutic use | Pyridazines - therapeutic use | Septic shock | Analysis | Patient outcomes | Epinephrine | Medical research | Cardiac patients | Medicine, Experimental | Index Medicus
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4. Full Text The disconnect between phase II and phase III trials of drugs for heart failure
by Vaduganathan, Muthiah and Greene, Stephen J and Ambrosy, Andrew P and Gheorghiade, Mihai and Butler, Javed
Nature reviews cardiology, ISSN 1759-5002, 02/2013, Volume 10, Issue 2, pp. 85 - 97
Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Natriuretic Peptide, Brain - therapeutic use | Patient Readmission | Risk Assessment | Humans | Risk Factors | Treatment Outcome | Xanthines - therapeutic use | Evidence-Based Medicine | Heart Failure - drug therapy | Patient Selection | Cardiovascular Agents - therapeutic use | Clinical Trials, Phase III as Topic | Animals | Time Factors | Benzazepines - therapeutic use | Hydrazones - therapeutic use | Tetrazoles - therapeutic use | Heart Failure - diagnosis | Cardiovascular Agents - adverse effects | Pyridazines - therapeutic use | Clinical Trials, Phase II as Topic | Heart Failure - mortality | Pyridines - therapeutic use | Heart failure | Clinical trials | Product development | Dosage and administration | Management | Drug therapy | Cardiovascular agents | Index Medicus
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5. Full Text Inotropic agents and vasodilator strategies for acute myocardial infarction complicated by cardiogenic shock or low cardiac output syndrome
by Unverzagt, Susanne and Wachsmuth, Lisa and Hirsch, Katharina and Thiele, Holger and Buerke, Michael and Haerting, Johannes and Werdan, Karl and Prondzinsky, Roland
Cochrane database of systematic reviews, ISSN 1469-493X, 2014, Volume 1, Issue 1, pp. CD009669 - 70
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Simendan | Vasodilator Agents - therapeutic use | Humans | Nitric Oxide - therapeutic use | Randomized Controlled Trials as Topic | Cardiac Output, Low - etiology | Cardiotonic Agents - therapeutic use | Myocardial Infarction - complications | Shock, Cardiogenic - drug therapy | Shock, Cardiogenic - etiology | Enoximone - therapeutic use | Hydrazones - therapeutic use | Cardiac Output, Low - drug therapy | Dobutamine - therapeutic use | Pyridazines - therapeutic use | Index Medicus
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