X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (46448) 46448
Publication (8381) 8381
Newsletter (2035) 2035
Book Chapter (303) 303
Book Review (273) 273
Conference Proceeding (123) 123
Book / eBook (84) 84
Government Document (46) 46
Newspaper Article (42) 42
Dissertation (27) 27
Data Set (3) 3
Magazine Article (3) 3
Paper (1) 1
Reference (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (18925) 18925
humans (17622) 17622
animals (15781) 15781
enzymes (12998) 12998
biochemistry & molecular biology (12335) 12335
molecular sequence data (10064) 10064
amino acid sequence (8680) 8680
hydrolases (8139) 8139
research (6587) 6587
microbiology (6535) 6535
proteins (6533) 6533
male (6201) 6201
mice (6157) 6157
female (5828) 5828
mutation (5549) 5549
base sequence (5285) 5285
expression (5221) 5221
biotechnology & applied microbiology (5211) 5211
analysis (5142) 5142
genetic aspects (4747) 4747
gene expression (4638) 4638
cell biology (4609) 4609
peptide hydrolases - metabolism (4479) 4479
cloning, molecular (4457) 4457
physiological aspects (4352) 4352
research article (4254) 4254
genes (4200) 4200
kinetics (3939) 3939
substrate specificity (3902) 3902
escherichia-coli (3578) 3578
gene (3576) 3576
phosphoric monoester hydrolases - genetics (3518) 3518
hydrolysis (3394) 3394
phosphoric monoester hydrolases - metabolism (3277) 3277
bacterial proteins - genetics (3207) 3207
escherichia coli - genetics (3197) 3197
glycoside hydrolases - metabolism (3170) 3170
multidisciplinary sciences (3107) 3107
genetics & heredity (3054) 3054
glycoside hydrolases - genetics (2997) 2997
purification (2991) 2991
bacterial proteins - metabolism (2876) 2876
biotechnology (2823) 2823
sequence homology, amino acid (2815) 2815
models, molecular (2784) 2784
cloning (2774) 2774
article (2773) 2773
identification (2767) 2767
bacteria (2742) 2742
protein (2739) 2739
rats (2702) 2702
life sciences (2636) 2636
biochemistry (2622) 2622
recombinant proteins - metabolism (2621) 2621
hydrolase (2611) 2611
adult (2337) 2337
peptide hydrolases - genetics (2313) 2313
carboxylic ester hydrolases - genetics (2305) 2305
dna (2278) 2278
cell line (2237) 2237
protein binding (2230) 2230
binding sites (2226) 2226
sequence alignment (2222) 2222
signal transduction (2211) 2211
middle aged (2180) 2180
oncology (2168) 2168
hydrogen-ion concentration (2141) 2141
phylogeny (2117) 2117
medicine (2096) 2096
genetic research (2091) 2091
hydrolases - genetics (2041) 2041
metabolism (2034) 2034
biophysics (2020) 2020
hydrolases - metabolism (1930) 1930
recombinant proteins - genetics (1891) 1891
catalysis (1870) 1870
science (1857) 1857
phosphorylation (1855) 1855
carboxylic ester hydrolases - metabolism (1843) 1843
plant sciences (1840) 1840
biology (1825) 1825
phenotype (1821) 1821
crystal-structure (1807) 1807
protein conformation (1797) 1797
cancer (1793) 1793
temperature (1775) 1775
sequence analysis, dna (1762) 1762
polymerase chain reaction (1755) 1755
protein structure, tertiary (1733) 1733
cells (1701) 1701
cells, cultured (1669) 1669
mutagenesis, site-directed (1658) 1658
amino acids (1633) 1633
escherichia coli (1626) 1626
degradation (1618) 1618
health aspects (1617) 1617
phosphoric diester hydrolases - metabolism (1615) 1615
proteases (1608) 1608
chemistry (1579) 1579
genetics (1546) 1546
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (51) 51
Collection Dvlpm't (Acquisitions) - Vendor file (8) 8
Chemistry (A D Allen) - Stacks (6) 6
UofT at Mississauga - Stacks (5) 5
Collection Dvlpm't (Acquisitions) - Closed Orders (3) 3
Online Resources - Online (3) 3
UTL at Downsview - May be requested (3) 3
Earth Sciences (Noranda) - Stacks (2) 2
Collection Dvlpm't (Acquisitions) - Cancelled Order (1) 1
Engineering & Comp. Sci. - Reference (1) 1
Gerstein Science - Missing (1) 1
Gerstein Science - Reference (1) 1
UofT at Mississauga - Reference (1) 1
UofT at Scarborough - Stacks (1) 1
UofT at Scarborough - Storage (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (47783) 47783
Chinese (303) 303
Russian (241) 241
Japanese (171) 171
French (93) 93
German (62) 62
Spanish (32) 32
Polish (29) 29
Italian (11) 11
Czech (6) 6
Hungarian (6) 6
Ukrainian (5) 5
Portuguese (4) 4
Dutch (3) 3
Korean (3) 3
Turkish (3) 3
Bulgarian (2) 2
Finnish (2) 2
Hebrew (2) 2
Romanian (1) 1
Serbian (1) 1
Slovenian (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Medical Genetics, ISSN 0022-2593, 12/2011, Volume 48, Issue 12, pp. 856 - 859
ObjectiveTo investigate the potential contribution of germline sequence alterations in the BAP1 gene in uveal melanoma (UM) patients with possible... 
BREAST-CANCER | GENE | HIGH-RISK | GENETICS & HEREDITY | TUMOR-SUPPRESSOR | BRCA1 | UBIQUITIN HYDROLASE | BRCA1-ASSOCIATED PROTEIN-1 | Adenocarcinoma - pathology | Genetic Testing | Adenocarcinoma of Lung | Humans | Lung Neoplasms - metabolism | Middle Aged | Gene Expression Regulation, Neoplastic | Genetic Diseases, Inborn - genetics | Lung Neoplasms - pathology | Male | Meningioma - genetics | Genetic Diseases, Inborn - pathology | Loss of Heterozygosity | Adenocarcinoma - metabolism | DNA Mutational Analysis | Melanoma - genetics | Tumor Suppressor Proteins - genetics | Germ-Line Mutation | Ubiquitin Thiolesterase - metabolism | Adult | Female | Adenocarcinoma - genetics | Genetic Diseases, Inborn - metabolism | Uveal Neoplasms - metabolism | Microsatellite Repeats | Lung Neoplasms - genetics | Melanoma - metabolism | Uveal Neoplasms - genetics | Genetic Predisposition to Disease - genetics | Tumor Suppressor Proteins - metabolism | Meningeal Neoplasms - genetics | Meningioma - metabolism | Uveal Neoplasms - pathology | Gene Silencing | Chromosomes, Human, Pair 3 - metabolism | Melanoma - pathology | Ubiquitin Thiolesterase - genetics | Meningioma - pathology | Pedigree | Meningeal Neoplasms - metabolism | Meningeal Neoplasms - pathology | Chromosomes, Human, Pair 3 - genetics | Genetic aspects | Research | BRCA mutations | Cancer
Journal Article
FEBS Journal, ISSN 1742-464X, 05/2010, Volume 277, Issue 10, pp. 2268 - 2281
TDP‐43 has recently been described as the major component of the inclusions found in the brain of patients with a variety of neurodegenerative diseases, such... 
microRNAs | miR‐663 | amyotrophic lateral sclerosis | TDP‐43 | let‐7b | Let-7b | Amyotrophic lateral sclerosis | MiR-663 | MicroRNAs | TDP-43 | BIOCHEMISTRY & MOLECULAR BIOLOGY | AMYOTROPHIC-LATERAL-SCLEROSIS | FRONTOTEMPORAL LOBAR DEGENERATION | let-7b | STRUCTURAL DETERMINANTS | RNA-BINDING PROTEIN | CELLULAR TOXICITY | miR-663 | EXPRESSION PATTERNS | DOWN-SYNDROME | GENE-EXPRESSION | CFTR EXON-9 | HNRNP A1 | RNA, Small Interfering - genetics | Protein Binding - genetics | Luciferases - metabolism | Gene Expression - genetics | Humans | MicroRNAs - metabolism | RNA, Messenger - metabolism | Luciferases - genetics | DNA-Binding Proteins - metabolism | Protein-Tyrosine Kinases - genetics | Qa-SNARE Proteins - genetics | Vesicle-Associated Membrane Protein 3 - genetics | Recombinant Proteins - metabolism | Base Sequence - genetics | Ribonuclease III - metabolism | Gene Expression Regulation - genetics | RNA, Messenger - genetics | Protein-Serine-Threonine Kinases - genetics | Genes, Reporter - genetics | Up-Regulation - genetics | Recombinant Proteins - genetics | DNA-Binding Proteins - genetics | Down-Regulation - genetics | Epoxide Hydrolases - genetics | Laminin - genetics | Cell Line, Tumor | MicroRNAs - genetics | HeLa Cells | Messenger RNA | Genetically modified organisms | Proteins | Brain | Biochemistry | Ribonucleic acid--RNA | Neurological disorders
Journal Article
PLoS Genetics, ISSN 1553-7390, 02/2010, Volume 6, Issue 2, p. e1000827
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 08/2017, Volume 102, Issue 8, pp. 3029 - 3039
Context: Only a few genetic causes for childhood obesity have been identified to date. Copy number variants (CNVs) are known to contribute to obesity, both... 
ENDOCRINOLOGY & METABOLISM | FAT | LOCI | MUTATIONS | REARRANGEMENTS | ASSOCIATION | DELETIONS | TYPE-2 | CONTRIBUTES | INSIGHTS | Hydrolases - genetics | Humans | DNA Repair Enzymes - genetics | Transcriptome | Child, Preschool | Male | Chromosome Duplication - genetics | RNA, Messenger - metabolism | Autoantigens - genetics | Case-Control Studies | DNA Copy Number Variations | Intellectual Disability - genetics | Young Adult | Chromosomes, Human, Pair 22 - genetics | Subcutaneous Fat - metabolism | Cell Cycle Proteins - genetics | Adult | Female | Chromosomes, Human, Pair 1 - genetics | Nuclear Proteins - genetics | Child | Microfilament Proteins - genetics | Abnormalities, Multiple - genetics | DiGeorge Syndrome - genetics | Chromosomes, Human, Pair 16 - genetics | Siblings | Autistic Disorder - genetics | Chromosome Deletion | Megalencephaly - genetics | Extracellular Matrix Proteins - genetics | Pediatric Obesity - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Proteins - genetics | Comparative Genomic Hybridization | Adolescent | Ataxia Telangiectasia Mutated Proteins - genetics | Kruppel-Like Transcription Factors - genetics | Acid Phosphatase - genetics | Chromosome Disorders - genetics | Adipose tissues | Obesity | Adipose tissue | Prader-Willi syndrome | Copy number | Genes | mRNA | Hybridization | Gene expression | Body mass index | DNA microarrays | Pathways | Clonal deletion | Ribonucleic acids | Body mass | Body size | Deletion | Children | Age | deletions | insights | bardet-biedl-syndrome | association | Klinisk medicin | contributes | population | type-2 | Clinical Medicine | mutations | rearrangements | Endocrinology & Metabolism | loci
Journal Article
Annual Review of Genomics and Human Genetics, ISSN 1527-8204, 2007, Volume 8, Issue 1, pp. 37 - 55
Each day tens of thousands of DNA single-strand breaks (SSBs) arise in every cell from the attack of deoxyribose and DNA bases by reactive oxygen species and... 
Cancer predisposition | Single-strand break | Neurodegeneration | Double-strand break | TUMOR-SUPPRESSOR GENES | neurodegeneration | cancer predisposition | TELANGIECTASIA-LIKE DISORDER | LIGASE-IV | CELL-FREE-EXTRACTS | DAMAGE RESPONSE | HISTONE H2AX PHOSPHORYLATION | I COVALENT COMPLEXES | single-strand break | GENETICS & HEREDITY | double-strand break | HOMOLOGY-DIRECTED REPAIR | ATAXIA-TELANGIECTASIA | FANCONI-ANEMIA PROTEIN | Microcephaly - genetics | DNA Ligases - genetics | Humans | DNA Repair - physiology | DNA Repair Enzymes - genetics | Genetic Diseases, Inborn - genetics | DNA Breaks, Double-Stranded | Phosphoric Diester Hydrolases - physiology | DNA Breaks, Single-Stranded | MRE11 Homologue Protein | Apraxias - genetics | Tumor Suppressor Proteins - genetics | Cell Cycle Proteins - genetics | DNA Ligases - physiology | Fanconi Anemia - genetics | Nuclear Proteins - genetics | Spinocerebellar Ataxias - genetics | DNA Repair Enzymes - physiology | DNA-Binding Proteins - physiology | Protein-Serine-Threonine Kinases - physiology | Protein-Serine-Threonine Kinases - genetics | Phosphoric Diester Hydrolases - genetics | Ataxia Telangiectasia Mutated Proteins | DNA-Binding Proteins - genetics | Nijmegen Breakage Syndrome - genetics | Syndrome | Severe Combined Immunodeficiency - genetics | Tumor Suppressor Proteins - physiology | Genes, BRCA1 - physiology | Genes, BRCA2 - physiology | Endonucleases | DNA Ligase ATP | Ataxia Telangiectasia - genetics | Nuclear Proteins - physiology | Cell Cycle Proteins - physiology
Journal Article
The EMBO Journal, ISSN 0261-4189, 02/2015, Volume 34, Issue 3, pp. 307 - 325
The protein kinase PINK 1 was recently shown to phosphorylate ubiquitin (Ub) on Ser65, and phosphoUb activates the E3 ligase Parkin allosterically. Here, we... 
PINK1 | phosphorylation | deubiquitinase | ubiquitin | Parkin | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | 63-LINKED POLYUBIQUITIN CHAINS | DAMAGED MITOCHONDRIA | CELL BIOLOGY | E3 LIGASE | ACTIVATE PARKIN | BINDING PROTEINS | CROSS-REACTIVITY | CONJUGATING ENZYME | REVEALS | Phosphorylation - physiology | Ubiquitin-Specific Proteases - genetics | Humans | Endosomal Sorting Complexes Required for Transport - genetics | Mitochondrial Proteins - genetics | Phosphoproteins - metabolism | Polyubiquitin - genetics | Allosteric Regulation - physiology | Mitochondrial Proteins - metabolism | Protein Multimerization - physiology | Ubiquitin Thiolesterase - metabolism | TNF Receptor-Associated Factor 6 - genetics | Ubiquitination - physiology | Ubiquitin-Specific Proteases - metabolism | Polyubiquitin - metabolism | Protein Structure, Tertiary | Endopeptidases - metabolism | Endosomal Sorting Complexes Required for Transport - metabolism | Ubiquitin-Protein Ligases - metabolism | Serine - genetics | Ubiquitin-Conjugating Enzymes - genetics | Phosphoproteins - genetics | Transcription Factors - genetics | Ubiquitin Thiolesterase - genetics | Serine - metabolism | Hydrolysis | Transcription Factors - metabolism | Endopeptidases - genetics | Ubiquitin-Conjugating Enzymes - metabolism | Adaptor Proteins, Signal Transducing - genetics | TNF Receptor-Associated Factor 6 - metabolism | Thiolester Hydrolases - genetics | Thiolester Hydrolases - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Ubiquitin-Protein Ligases - genetics | Enzymes | Phosphorylation | Kinases | Crystal structure
Journal Article
Nature Genetics, ISSN 1061-4036, 09/2009, Volume 41, Issue 9, pp. 1027 - 1031
The primary cilium is an antenna-like structure that protrudes from the cell surface of quiescent/ differentiated cells and participates in extracellular... 
NETWORK | INOSITOL-POLYPHOSPHATE 5-PHOSPHATASE | POLYCYSTIC KIDNEY-DISEASE | BIOLOGY | GENETICS & HEREDITY | DISORDERS | PROTEINS | FIBROBLASTS | Humans | Fluorescent Dyes - metabolism | Culture Media, Serum-Free | Male | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Fibroblasts - ultrastructure | Obesity - genetics | Embryo, Mammalian - metabolism | Intellectual Disability - genetics | Indoles - metabolism | Tubulin - metabolism | Cell Nucleus - metabolism | Transfection | Mice, Mutant Strains | Cilia - ultrastructure | Bardet-Biedl Syndrome - genetics | Chromones - pharmacology | Microsatellite Repeats | Fibroblasts - metabolism | Genetic Linkage | Cell Line | Green Fluorescent Proteins - metabolism | Phosphoric Monoester Hydrolases - genetics | Cilia - pathology | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Fluorescent Antibody Technique, Direct | Retinal Degeneration - genetics | Cells, Cultured | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Mice, Transgenic | Genetic Markers | Cilia - metabolism | Cilia - genetics | Pigment Epithelium of Eye - metabolism | Animals | Embryo, Mammalian - cytology | Signal Transduction - physiology | Fibroblasts - cytology | Mice | Polymorphism, Single Nucleotide | Mutation | Pigment Epithelium of Eye - cytology | Penis - abnormalities | Gene mutations | Genetic aspects | Cellular signal transduction | Research | Health aspects | Risk factors | Brain diseases | Proteins | Tissue | Scanning electron microscopy | Transmission electron microscopy | Cysts | Rodents | Cell division
Journal Article
by Pattaro, Cristian and Köttgen, Anna and Teumer, Alexander and Böger, Carsten and Fuchsberger, Christian and Olden, Matthias and Chen, Ming-Huei and Li, Man and Gao, Xiaoyi and Gorski, Mathias and Yang, Qiong Fang and O'Seaghdha, Conall and Glazer, Nicole and Isaacs, Aaron and Liu, Ching-Ti and Smith, Albert Vernon and O´Connell, J.R and Struchalin, Maksim and Tanaka, Toshiko and Johnson, Anew and Feitosa, Mary Furlan and Hwang, S.J and Lohman, Kurt and Cornelis, Marilyn and Johansson, Åsa and Tönjes, Anke and Dehghan, Abbas and Chouraki, Vincent and Holliday, Elizabeth and Sorice, R and Kutalik, Zoltán and Lehtimäki, Terho and Esko, Tõnu and Ulivi, Shelia and Trompet, Stella and Imboden, Medea and Kollerits, Barbara and Pistis, Giorgio and Harris, Tamara and Launer, Lenore and Aspelund, Thor and Eiriksdottir, Gudny and Mitchell, Braxton and Boerwinkle, Eric and Schmidt, Reinhold and Cavalieri, Margherita and Hu, Frank and Demirkan, Ayşe and Oostra, Ben and Anade, Mariza and Anews, Jeanette and Koenig, Wolfgang and Illig, Thomas and Döring, Angela and Wichmann, Erich and Kolcic, Ivana and Zemunik, Tatijana and Boban, Mladen and Igl, Wilmar and Zaboli, Ghazal and Wild, Sarah and Wright, Alan and Campbell, Harry and Biffar, Reiner and Ernst, Florian and Homuth, Georg and Kroemer, Heyo and Nauck, Matthias and Kovacs, Peter and Stumvoll, Michael and Mägi, Reedik and Hofman, Albert and Uitterlinden, Ané and Rivadeneira Ramirez, Fernando and Aulchenko, Yurii and Polasek, Ozren and Hastie, Nick and Vitart, Veronique and Wang, Jie Jin and Bergmann, Sven and Kähönen, Mika and Viikari, Jorma and Province, Mike and Ketkar, Shamika and Doney, Alex and Ford, Ian and Buckley, Brendan M and Paulweber, Bernhard and Haun, Margot and Sala, Cinzia and Ciullo, M and Vollenweider, Peter and Raitakari, Olli and Metspalu, Anes and Palmer, Colin and Gasparini, Paolo and Jukema, Jan Wouter and Kronenberg, Florian and Toniolo, Daniela and Gudnason, Vilmundur and ... and CARDIoGRAM Consortium and ICBP Consortium and WTCCC2 and CARe Consortium and Wellcome Trust Case Control Consortium 2 (WTCCC2) and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Genomik and Uppsala universitet
PL o S Genetics (Online), ISSN 1553-7390, 03/2012, Volume 8, Issue 3, p. e1002584
Journal Article