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Nature Genetics, ISSN 1061-4036, 09/2009, Volume 41, Issue 9, pp. 1027 - 1031
The primary cilium is an antenna-like structure that protrudes from the cell surface of quiescent/differentiated cells and participates in extracellular signal... 
NETWORK | INOSITOL-POLYPHOSPHATE 5-PHOSPHATASE | POLYCYSTIC KIDNEY-DISEASE | BIOLOGY | GENETICS & HEREDITY | DISORDERS | PROTEINS | FIBROBLASTS | Humans | Fluorescent Dyes - metabolism | Culture Media, Serum-Free | Male | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Fibroblasts - ultrastructure | Obesity - genetics | Embryo, Mammalian - metabolism | Intellectual Disability - genetics | Indoles - metabolism | Tubulin - metabolism | Cell Nucleus - metabolism | Transfection | Mice, Mutant Strains | Cilia - ultrastructure | Bardet-Biedl Syndrome - genetics | Chromones - pharmacology | Microsatellite Repeats | Fibroblasts - metabolism | Genetic Linkage | Cell Line | Green Fluorescent Proteins - metabolism | Phosphoric Monoester Hydrolases - genetics | Cilia - pathology | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Fluorescent Antibody Technique, Direct | Retinal Degeneration - genetics | Cells, Cultured | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Mice, Transgenic | Genetic Markers | Cilia - metabolism | Cilia - genetics | Pigment Epithelium of Eye - metabolism | Animals | Embryo, Mammalian - cytology | Signal Transduction - physiology | Fibroblasts - cytology | Mice | Polymorphism, Single Nucleotide | Mutation | Pigment Epithelium of Eye - cytology | Penis - abnormalities | Gene mutations | Genetic aspects | Cellular signal transduction | Research | Health aspects | Risk factors | Brain diseases | Proteins | Tissue | Scanning electron microscopy | Transmission electron microscopy | Cysts | Rodents | Cell division | Index Medicus
Journal Article
Cell Metabolism, ISSN 1550-4131, 05/2012, Volume 15, Issue 5, pp. 665 - 674
Nonalcoholic fatty liver disease (NAFLD) is associated with increased cardiovascular and liver-related mortality. NAFLD is characterized by both triglyceride... 
RAT-LIVER | RISK-FACTORS | MACROPHAGE APOPTOSIS | PROTEIN-KINASE | ENDOCRINOLOGY & METABOLISM | HMG-COA REDUCTASE | STEATOHEPATITIS | 3-HYDROXY-3-METHYLGLUTARYL COENZYME | PREVALENCE | MICRORNA EXPRESSION | MODULATION | CELL BIOLOGY | Sirtuin 1 - metabolism | Up-Regulation | Cholesterol - blood | Humans | Middle Aged | Sterol Esterase - metabolism | Male | MicroRNAs - metabolism | Desmosterol - metabolism | Cardiovascular Diseases - genetics | Cholesterol - genetics | Sirtuin 1 - genetics | Case-Control Studies | Phosphorylation - genetics | Hydroxymethylglutaryl CoA Reductases - metabolism | Adenylate Kinase - metabolism | Non-alcoholic Fatty Liver Disease | Sterol O-Acyltransferase - metabolism | Adult | Female | Lipid Metabolism - genetics | Sterol Regulatory Element Binding Protein 2 - genetics | Sterol Regulatory Element Binding Protein 2 - metabolism | Fatty Liver - genetics | Receptors, LDL - genetics | Gene Expression | Fatty Liver - metabolism | Cardiovascular Diseases - metabolism | Fatty Liver - blood | Liver - metabolism | Receptors, LDL - metabolism | Cholesterol - metabolism | Cholesterol, LDL - genetics | Phenotype | Sterol Esterase - genetics | Desmosterol - blood | Cholesterol, LDL - metabolism | MicroRNAs - genetics | Sterol O-Acyltransferase - genetics | Adenylate Kinase - genetics | Hydroxymethylglutaryl CoA Reductases - genetics | Enzymes | Liver diseases | Low density lipoproteins | Genes | Esters | Triglycerides | Cholesterol | MicroRNA | Fatty liver | Blood cholesterol | Physiological aspects | Hydrolases | Blood lipids | Health aspects | Statins | Index Medicus | atherosclerosis | Nonalcoholic steatohepatitis | cholesterol | Nonalcoholic fatty liver disease | fatty liver | lipogenesis | hypercholesterolemia | HMG CoA reductase
Journal Article
The Plant Cell, ISSN 1040-4651, 3/2010, Volume 22, Issue 3, pp. 973 - 990
Despite the fact that roots are the organs most subject to microbial interactions, very little is known about the response of roots to microbe-associated... 
Pathogens | Microorganisms | Rhizodeposition | Plant roots | Bacteria | Chitin | Biosynthesis | Plants | Seedlings | Plant cells | ALTERNARIA-BRASSICICOLA | BIOCHEMISTRY & MOLECULAR BIOLOGY | PSEUDOMONAS-SYRINGAE | SYSTEMIC ACQUIRED-RESISTANCE | PLANT SCIENCES | CELL BIOLOGY | PHYTOTOXIN CORONATINE | NONHOST RESISTANCE | SALICYLIC-ACID | METHYL JASMONATE | PLANT DEFENSE | RHIZOSPHERE BACTERIA | PHYTOALEXIN CAMALEXIN | Peptidoglycan - metabolism | Thiazoles - metabolism | Salicylic Acid - metabolism | Arabidopsis - immunology | Cytochrome P-450 Enzyme System - metabolism | Plant Roots - genetics | Pseudomonas | Ethylenes - metabolism | Arabidopsis Proteins - metabolism | Indoles - metabolism | Chitin - metabolism | Glucans - metabolism | Plant Roots - metabolism | Plants, Genetically Modified - genetics | Signal Transduction | Plants, Genetically Modified - immunology | RNA, Plant - genetics | Arabidopsis - metabolism | N-Glycosyl Hydrolases - metabolism | Arabidopsis - genetics | Host-Pathogen Interactions | Oxylipins - metabolism | Flagella - metabolism | Plants, Genetically Modified - metabolism | Plant Roots - immunology | Cyclopentanes - metabolism | Arabidopsis thaliana | Immune response | Plant molecular genetics | Diseases and pests | Roots (Botany) | Genetic aspects | Research | Index Medicus | Life Sciences | Cellular Biology
Journal Article
Ecotoxicology and Environmental Safety, ISSN 0147-6513, 01/2018, Volume 147, pp. 990 - 1001
Journal Article
The EMBO Journal, ISSN 0261-4189, 02/2015, Volume 34, Issue 3, pp. 307 - 325
The protein kinase PINK 1 was recently shown to phosphorylate ubiquitin (Ub) on Ser65, and phosphoUb activates the E3 ligase Parkin allosterically. Here, we... 
PINK1 | phosphorylation | deubiquitinase | ubiquitin | Parkin | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | 63-LINKED POLYUBIQUITIN CHAINS | DAMAGED MITOCHONDRIA | CELL BIOLOGY | E3 LIGASE | ACTIVATE PARKIN | BINDING PROTEINS | CROSS-REACTIVITY | CONJUGATING ENZYME | REVEALS | Phosphorylation - physiology | Ubiquitin-Specific Proteases - genetics | Humans | Endosomal Sorting Complexes Required for Transport - genetics | Mitochondrial Proteins - genetics | Phosphoproteins - metabolism | Polyubiquitin - genetics | Allosteric Regulation - physiology | Mitochondrial Proteins - metabolism | Protein Multimerization - physiology | Ubiquitin Thiolesterase - metabolism | TNF Receptor-Associated Factor 6 - genetics | Ubiquitination - physiology | Ubiquitin-Specific Proteases - metabolism | Polyubiquitin - metabolism | Protein Structure, Tertiary | Endopeptidases - metabolism | Endosomal Sorting Complexes Required for Transport - metabolism | Ubiquitin-Protein Ligases - metabolism | Serine - genetics | Ubiquitin-Conjugating Enzymes - genetics | Phosphoproteins - genetics | Transcription Factors - genetics | Ubiquitin Thiolesterase - genetics | Serine - metabolism | Hydrolysis | Transcription Factors - metabolism | Endopeptidases - genetics | Ubiquitin-Conjugating Enzymes - metabolism | Adaptor Proteins, Signal Transducing - genetics | TNF Receptor-Associated Factor 6 - metabolism | Thiolester Hydrolases - genetics | Thiolester Hydrolases - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Ubiquitin-Protein Ligases - genetics | Enzymes | Phosphorylation | Kinases | Crystal structure | Index Medicus
Journal Article
Science, ISSN 0036-8075, 1/2009, Volume 323, Issue 5910, pp. 101 - 106
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 502, Issue 7472, pp. 571 - 574
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2015, Volume 290, Issue 22, pp. 13875 - 13887
Journal Article
Plant Cell, ISSN 1040-4651, 10/2014, Volume 26, Issue 10, pp. 4119 - 4134
Triacylglycerol (TAG) metabolism is a key aspect of intracellular lipid homeostasis in yeast and mammals, but its role in vegetative tissues of plants remains... 
DIACYLGLYCEROL ACYLTRANSFERASE | CONTACT SITES | SHORT-CHAIN | CHLOROPLAST INNER ENVELOPE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHOSPHOLIPID-SYNTHESIS | CARRIER PROTEIN | PLANT SCIENCES | CELL BIOLOGY | OIL CATABOLISM | METABOLISM | ENDOPLASMIC-RETICULUM | PHOSPHATIDIC-ACID | Homeostasis | Acyltransferases - metabolism | Acyltransferases - genetics | Arabidopsis Proteins - metabolism | Lipid Droplets - ultrastructure | ATP-Binding Cassette Transporters - genetics | Membrane Transport Proteins - genetics | beta-Glucosidase - genetics | Plants, Genetically Modified | Gene Expression Regulation, Plant | ATP-Binding Cassette Transporters - metabolism | beta-Glucosidase - metabolism | Membrane Transport Proteins - metabolism | Carboxylic Ester Hydrolases - genetics | Lipid Droplets - metabolism | Fatty Acids - metabolism | Microscopy, Electron, Transmission | Arabidopsis Proteins - genetics | Oxidation-Reduction | Lipase - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Peroxisomes - metabolism | Arabidopsis - metabolism | Triglycerides - metabolism | Arabidopsis - genetics | Plant Leaves - genetics | Plant Leaves - metabolism | Models, Biological | Membrane Lipids - metabolism | Mutation | Microscopy, Fluorescence | Plant Leaves - ultrastructure | Carboxylic Ester Hydrolases - metabolism | Lipase - genetics | Index Medicus
Journal Article
Journal Article
Science, ISSN 0036-8075, 5/2006, Volume 312, Issue 5774, pp. 734 - 737
Fat tissue is the most important energy depot in vertebrates. The release of free fatty acids (FFAs) from stored fat requires the enzymatic activity of... 
Adipose tissues | Fasting | Liver | Nonesterified fatty acids | Myocardium | Lipids | Reports | Triglycerides | Mice | Insulin | Lipolysis | LIPOTOXICITY | CELLS | HORMONE-SENSITIVE LIPASE | MOBILIZATION | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | TISSUE | HUMAN OBESITY | ACCUMULATION | EXPRESSION | DEFICIENCY | Testis - metabolism | Lipolysis - drug effects | Homeostasis | Adipocytes - cytology | Male | Insulin - blood | Adipose Tissue - metabolism | Fatty Acids, Nonesterified - metabolism | Kidney - metabolism | Lipids - blood | Myocardium - metabolism | Fatty Acids, Nonesterified - blood | Female | Carboxylic Ester Hydrolases - genetics | Lipase - deficiency | Adipose Tissue - anatomy & histology | Myocytes, Cardiac - cytology | Carboxylic Ester Hydrolases - deficiency | Oxygen Consumption | Cell Size | Myocardium - pathology | Heart Failure - pathology | Lipase - metabolism | Adipose Tissue, Brown - enzymology | Ventricular Dysfunction, Left - physiopathology | Triglycerides - metabolism | Animals | Thermogenesis | Energy Metabolism | Adipocytes - metabolism | Isoproterenol - pharmacology | Myocytes, Cardiac - metabolism | Adipose Tissue - enzymology | Blood Glucose - metabolism | Carboxylic Ester Hydrolases - metabolism | Lipase - genetics | Physiological aspects | Research | Metabolism | Heart | Enzymes | Body fat | Rodents | Glucose | Index Medicus
Journal Article