X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (2973) 2973
Book Review (150) 150
Publication (150) 150
Newsletter (10) 10
Book Chapter (5) 5
Conference Proceeding (5) 5
Web Resource (2) 2
Book / eBook (1) 1
Government Document (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (2669) 2669
animals (1517) 1517
hydroquinones - pharmacology (1512) 1512
humans (1119) 1119
hydroquinone (758) 758
male (597) 597
pharmacology & pharmacy (595) 595
rats (576) 576
biochemistry & molecular biology (564) 564
mice (505) 505
toxicology (430) 430
antioxidants - pharmacology (321) 321
female (320) 320
hydroquinones - metabolism (315) 315
chemistry, medicinal (295) 295
enzyme inhibitors - pharmacology (293) 293
hydroquinones - chemistry (291) 291
oxidation-reduction (287) 287
oxidative stress (284) 284
dose-response relationship, drug (280) 280
cells, cultured (266) 266
hydroquinones - toxicity (254) 254
in vitro techniques (228) 228
calcium - metabolism (215) 215
kinetics (211) 211
hydroquinones (203) 203
cells (194) 194
benzene (182) 182
cell line (179) 179
activation (173) 173
cell survival - drug effects (172) 172
apoptosis (171) 171
cell line, tumor (169) 169
antioxidants (168) 168
cell biology (168) 168
toxicity (158) 158
time factors (157) 157
molecular structure (155) 155
metabolites (153) 153
inhibition (150) 150
analysis (149) 149
structure-activity relationship (143) 143
apoptosis - drug effects (141) 141
phosphorylation (136) 136
phenols - pharmacology (135) 135
dermatology (134) 134
calcium-transporting atpases - antagonists & inhibitors (131) 131
enzymes (129) 129
expression (125) 125
tumor cells, cultured (125) 125
chemistry, multidisciplinary (121) 121
oncology (121) 121
reactive oxygen species - metabolism (121) 121
antineoplastic agents - pharmacology (119) 119
research (118) 118
induction (116) 116
metabolism (116) 116
adult (115) 115
biophysics (115) 115
quinone (114) 114
in-vitro (113) 113
quinones - pharmacology (113) 113
glutathione - metabolism (112) 112
cytotoxicity (109) 109
protein-tyrosine kinases - antagonists & inhibitors (107) 107
oxidation (106) 106
chemistry (105) 105
benzene - metabolism (104) 104
rats, sprague-dawley (104) 104
nf-e2-related factor 2 - metabolism (103) 103
oxidative stress - drug effects (103) 103
skin (102) 102
cancer (101) 101
glutathione (101) 101
nrf2 (101) 101
hydroquinones - administration & dosage (100) 100
proteins (99) 99
dna damage (95) 95
physiological aspects (95) 95
benzene - toxicity (94) 94
mechanism (94) 94
thapsigargin (94) 94
cattle (93) 93
hydroquinones - isolation & purification (93) 93
phenols (92) 92
quinones (91) 91
catechols - pharmacology (88) 88
signal transduction (88) 88
hydrogen-ion concentration (86) 86
biotechnology & applied microbiology (85) 85
gene-expression (85) 85
hydroquinones - chemical synthesis (84) 84
hydroquinones - therapeutic use (84) 84
rats, wistar (84) 84
liver - drug effects (83) 83
phenol (82) 82
middle aged (81) 81
physiology (79) 79
rabbits (79) 79
article (78) 78
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (2848) 2848
German (32) 32
French (28) 28
Russian (27) 27
Japanese (26) 26
Chinese (17) 17
Portuguese (6) 6
Italian (4) 4
Spanish (3) 3
Polish (1) 1
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Free Radical Biology and Medicine, ISSN 0891-5849, 08/2012, Volume 53, Issue 4, pp. 817 - 827
The Keap1-Nrf2 system plays a critical role in cellular defense against electrophiles and reactive oxygen species. Keap1 possesses a number of cysteine... 
Keap1 | Reactive cysteine | Stress response | Nrf2 | OXIDATIVE STRESS | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CDDO-IM | PHASE-2 RESPONSE | ANTIOXIDANT | COVALENT MODIFICATION | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | NITRIC-OXIDE | CYSTEINE RESIDUES | Oxidants - pharmacology | Maleates - pharmacology | Cytoskeletal Proteins - genetics | Humans | Oleanolic Acid - analogs & derivatives | Transcriptional Activation - drug effects | Oleanolic Acid - pharmacology | NAD(P)H Dehydrogenase (Quinone) - genetics | Hydroquinones - pharmacology | Organoselenium Compounds - pharmacology | HEK293 Cells | Cytoskeletal Proteins - metabolism | NF-E2-Related Factor 2 - genetics | Glutamate-Cysteine Ligase - metabolism | Dimethyl Fumarate | Kelch-Like ECH-Associated Protein 1 | Macrophages, Peritoneal - drug effects | Isothiocyanates - pharmacology | Gene Expression | Mice, Transgenic | Imidazoles - pharmacology | Antioxidants - pharmacology | Azoles - pharmacology | Gene Expression Regulation - drug effects | Animals | Fumarates - pharmacology | NF-E2-Related Factor 2 - metabolism | Adaptor Proteins, Signal Transducing - genetics | NAD(P)H Dehydrogenase (Quinone) - metabolism | Glutamate-Cysteine Ligase - genetics | Mice | Oxidative Stress - drug effects | Adaptor Proteins, Signal Transducing - metabolism | Macrophages, Peritoneal - metabolism | Amino Acid Substitution | Purines | Cysteine | Dimethylformamide | Ligases | Quinone | Transplantation of organs, tissues, etc | Universities and colleges | Macrophages | Cystine | Index Medicus | stress response | reactive cysteine
Journal Article
Experimental Parasitology, ISSN 0014-4894, 04/2019, Volume 199, pp. 17 - 23
Exposing second-stage juveniles (J2) of to a phenolic compound sometimes fails to cause J2 mortality, but in tests the same compound may reduce the infectivity... 
Hydroquinone | Phenols | Root-knot nematode | Tomato | Solanum lycopersicum | ROOT-KNOT NEMATODES | RESISTANCE | NEMATOCIDAL ACTIVITY | PSI-BLAST | PARASITOLOGY | Hydroxybenzoates - administration & dosage | Tylenchoidea - drug effects | Hydroquinones - administration & dosage | Arbutin - administration & dosage | Hydroquinones - chemistry | Caffeic Acids - pharmacology | Catechols - chemistry | Glycerol - administration & dosage | Naphthols - chemistry | Hydroquinones - pharmacology | Resorcinols - administration & dosage | Arbutin - pharmacology | Resorcinols - pharmacology | Hydroxybenzoates - pharmacology | Time Factors | Hydroxybenzoates - chemistry | Catechols - pharmacology | Naphthols - administration & dosage | Glycerol - pharmacology | Glycerol - chemistry | Carbofuran - chemistry | Phenols - pharmacology | Caffeic Acids - administration & dosage | Benzaldehydes - chemistry | Carbofuran - pharmacology | Naphthols - pharmacology | Benzaldehydes - pharmacology | Caffeic Acids - chemistry | Lethal Dose 50 | Random Allocation | Arbutin - chemistry | Animals | Benzaldehydes - administration & dosage | Carbofuran - administration & dosage | Resorcinols - chemistry | Lycopersicon esculentum - parasitology | Phenols - administration & dosage | Phenols - chemistry | Catechols - administration & dosage | Plants | Tomatoes | Nematoda | Index Medicus
Journal Article
Toxicological Sciences, ISSN 1096-6080, 4/2007, Volume 96, Issue 2, pp. 227 - 236
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 04/2008, Volume 294, Issue 4, pp. 1724 - 1735
In septic shock, systemic vasodilation and myocardial depression contribute to the systemic hypotension observed. Both components can be attributed to the... 
Compound I | Septic shock | Reactive oxygen species | Catalase | Hydroxyl radical | Hypotension | hypotension | septic shock | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | ESCHERICHIA-COLI | H2O2 | MYOCARDIAL DEPRESSION | compound I | ASCORBATE | hydroxyl radical | reactive oxygen species | VASCULAR FUNCTION | DOGS | NITRIC-OXIDE | PERIPHERAL VASCULAR DISEASE | DYSFUNCTION | BINDING | catalase | Free Radical Scavengers - pharmacology | Cyclic GMP - pharmacology | Carotid Artery, Internal - drug effects | Humans | Carotid Artery, Internal - metabolism | Cyclic GMP-Dependent Protein Kinases - antagonists & inhibitors | Time Factors | Oxadiazoles - pharmacology | Sepsis - metabolism | Muramidase - antagonists & inhibitors | Vasoconstrictor Agents - pharmacology | Enzyme Inhibitors - pharmacology | Soluble Guanylyl Cyclase | Muramidase - metabolism | Thionucleotides - pharmacology | Methylene Blue - pharmacology | Sepsis - physiopathology | Indomethacin - pharmacology | Carotid Artery, Internal - enzymology | Hydrogen Peroxide - metabolism | Mesenteric Artery, Superior - enzymology | Mesenteric Artery, Superior - metabolism | Cyclic GMP - metabolism | Signal Transduction - drug effects | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Nitric Oxide Synthase - metabolism | Vasodilation - drug effects | Receptors, Cytoplasmic and Nuclear - metabolism | Nitric Oxide Synthase - antagonists & inhibitors | omega-N-Methylarginine - pharmacology | Guanylate Cyclase - antagonists & inhibitors | Hydroquinones - pharmacology | Cyclic GMP-Dependent Protein Kinases - metabolism | Mannitol - pharmacology | Dose-Response Relationship, Drug | Quinoxalines - pharmacology | Phenylephrine - pharmacology | Cyclic GMP - analogs & derivatives | Aminoquinolines - pharmacology | Guanylate Cyclase - metabolism | Mesenteric Artery, Superior - drug effects | Cyclooxygenase Inhibitors - pharmacology | Catalase - metabolism | Ethanol - pharmacology | Animals | Dogs | Protein Kinase Inhibitors - pharmacology | In Vitro Techniques | Nitric Oxide - metabolism | Prostaglandins - metabolism | Studies | Blood vessels | Signal transduction | Enzymes | Nitric oxide | Cells | Index Medicus
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 2009, Volume 182, Issue 1, pp. 37 - 44
The proved radio- and chemo-sensitizing capacity of genistein supports the potential use of this isoflavone in antitumour therapies. In this regard, we... 
Arsenic trioxide | Genistein | Tyrosine kinase inhibitors | Apoptosis | Mitogen-activated protein kinases | U937 leukaemia cells | CANCER-CELLS | ESTROGEN-RECEPTORS | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | OXYGEN SPECIES GENERATION | TYROSINE KINASES | SIGNAL-TRANSDUCTION | HUMAN PROMONOCYTIC CELLS | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | HYDROGEN-PEROXIDE | TOXICOLOGY | GLUTATHIONE DEPLETION | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Humans | Immunoblotting | Hydroquinones - pharmacology | U937 Cells | Antineoplastic Agents - pharmacology | Catechin - pharmacology | Estradiol - pharmacology | Adamantane - analogs & derivatives | Adamantane - pharmacology | Arsenicals - pharmacology | RNA, Small Interfering - pharmacology | Etoposide - pharmacology | Antioxidants - pharmacology | Drug Synergism | Oxides - pharmacology | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Genistein - pharmacology | HL-60 Cells | Catechin - analogs & derivatives | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Cell Cycle - drug effects | Microscopy, Fluorescence | Mitogen-Activated Protein Kinases - metabolism | Tyrosine | Cysteine | Catechin | Arsenic | Leukemia | Estrogen | Etoposide | Antioxidants | Analysis | Angiogenesis inhibitors | Protein kinases | Isoflavones | Index Medicus
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 05/2006, Volume 97, Issue 3, pp. 687 - 696
Astrocytes may modulate the survival of motor neurons in amyotrophic lateral sclerosis (ALS). We have previously shown that fibroblast growth factor‐1 (FGF‐1)... 
motor neurons | astrocytes | nuclear factor erythroid 2‐related factor 2 | p75 neurotrophin receptor | amyotrophic lateral sclerosis | glutathione | Motor neurons | Amyotrophic lateral sclerosis | Astrocytes | Glutathione | Nuclear factor erythroid 2-related factor 2 | Propionates - pharmacology | Embryo, Mammalian | Glutathione - metabolism | Nitrites - metabolism | Methionine - pharmacology | Glial Fibrillary Acidic Protein - metabolism | Hydroquinones - pharmacology | Quinolines - pharmacology | RNA, Messenger - biosynthesis | Glutathione - biosynthesis | Drug Interactions | Transfection - methods | Methionine - analogs & derivatives | Reverse Transcriptase Polymerase Chain Reaction - methods | Urea - analogs & derivatives | Spinal Cord - cytology | Receptor, Nerve Growth Factor - metabolism | Animals, Newborn | Astrocytes - drug effects | Cell Survival - drug effects | Blotting, Western - methods | Motor Neurons - physiology | Animals, Genetically Modified | Cells, Cultured | Nerve Growth Factor - pharmacology | Rats | Antioxidants - pharmacology | Pyrimidines - pharmacology | Coculture Techniques - methods | Enzyme Activation - drug effects | Rats, Sprague-Dawley | Nitrates - metabolism | Animals | Cell Count - methods | NF-E2-Related Factor 2 - metabolism | Fibroblast Growth Factor 1 - pharmacology | Urea - pharmacology | Astrocytes - metabolism | Nitric Oxide Synthase Type II - metabolism | Superoxide Dismutase | Neurosciences | Inhibitor drugs | Gene expression | Neurons | Spine | Motor ability | Index Medicus
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 2006, Volume 72, Issue 3, pp. 366 - 376
NRH:quinone oxidoreductase 2 (NQO2) is a cytosolic flavoprotein that utilizes NRH as electron donor. The present studies investigate the role of NQO2 in... 
Anti-tumor drugs | NRH:quinone oxidoreductase 2 | Metabolic activation | Quinones | Cytotoxicity | Mitomycin C | mitomycin C | anti-tumor drugs | CANCER-CHEMOTHERAPY | TISSUE-SPECIFIC EXPRESSION | NRH : quinone oxidoreductase 2 | OXIDOREDUCTASE-1 DEFICIENCY | MENADIONE TOXICITY | INCREASES SUSCEPTIBILITY | GENE | DT-DIAPHORASE | metabolic activation | SKIN CARCINOGENESIS | REDUCTASE | PHARMACOLOGY & PHARMACY | quinones | cytotoxicity | MOUSE SKIN | Cricetulus | Cross-Linking Reagents - pharmacology | DNA, Complementary - genetics | Hydroquinones - metabolism | Hydroquinones - pharmacology | Indolequinones - metabolism | Antineoplastic Agents - metabolism | Dose-Response Relationship, Drug | Mitomycins - pharmacology | Transfection | Antineoplastic Agents - pharmacology | Benzopyrenes - pharmacology | Quinones - pharmacology | CHO Cells | Quinones - metabolism | Cell Survival - drug effects | Quinone Reductases - metabolism | Cricetinae | Cells, Cultured | Indolequinones - pharmacology | Aziridines - pharmacology | Keratinocytes - cytology | Mice, Knockout | Mitomycin - pharmacology | Cross-Linking Reagents - metabolism | Vitamin K 3 - pharmacology | Vitamin K 3 - metabolism | Animals | Keratinocytes - drug effects | Keratinocytes - metabolism | Biotransformation - drug effects | Benzopyrenes - metabolism | Quinone Reductases - genetics | Mice | Aziridines - metabolism | Mitomycin - metabolism | Mitomycins - metabolism | Niacinamide | Mitomycin | Histidine | Hamsters | Quinone | Skin cancer | Index Medicus
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 3/2018, Volume 81, Issue 3, pp. 483 - 495
Amongst the epigenetically targeted therapies, targeting of the histone deacetylases (HDACs) has yielded numerous drugs for clinical use in hematological... 
Oxidative stress | ALL | Medicine & Public Health | ROS | HDAC inhibitor | Oncology | Cancer Research | Pharmacology/Toxicology | HDAC | APOPTOSIS | MS-275 | HUMAN LEUKEMIA-CELLS | INDUCTION | IDENTIFICATION | IN-VITRO | COMBINATIONS | ONCOLOGY | PROSTATE-CANCER | MYELOID-LEUKEMIA | PHARMACOLOGY & PHARMACY | CYTOTOXICITY | Adamantane - pharmacology | Oxidation-Reduction | Apoptosis - drug effects | Humans | Vorinostat - pharmacology | Histone Deacetylases - metabolism | Gene Expression Profiling | Hydroquinones - pharmacology | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Cell Line, Tumor | Histone Deacetylase Inhibitors - pharmacology | Antineoplastic Agents - pharmacology | Benzamides - pharmacology | Pyridines - pharmacology | DNA Fragmentation - drug effects | Oxidative Stress - drug effects | Drug Therapy, Combination | Adamantane - analogs & derivatives | Antioxidants | Epigenetic inheritance | Cell death | Analysis | Leukemia | Superoxide | Gene expression | Drugs | Histone deacetylase | Divergence | Gene regulation | Acetylcysteine | Activation | Mitochondrial DNA | Fragmentation | Reduction | DNA fragmentation | Peroxides | Membrane potential | Deoxyribonucleic acid--DNA | Glutathione | Hematology | Caspase | Lymphatic leukemia | Inhibitors | Cell lines | Caspase-9 | Intracellular | Combinatorial analysis | Apoptosis | Index Medicus | oxidative stress
Journal Article
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2000, Volume 97, Issue 23, pp. 12475 - 12480
Journal Article