X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (8369) 8369
Book Chapter (16) 16
Publication (3) 3
Conference Proceeding (2) 2
Magazine Article (2) 2
Web Resource (2) 2
Book / eBook (1) 1
Book Review (1) 1
Dissertation (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
hydroxamic acids - pharmacology (6086) 6086
humans (5173) 5173
animals (3668) 3668
histone deacetylase inhibitors (2288) 2288
histone deacetylase inhibitors - pharmacology (2132) 2132
cell line, tumor (1918) 1918
mice (1887) 1887
enzyme inhibitors - pharmacology (1710) 1710
oncology (1582) 1582
acetylation (1490) 1490
biochemistry & molecular biology (1475) 1475
male (1402) 1402
apoptosis (1334) 1334
female (1332) 1332
cancer (1320) 1320
expression (1309) 1309
histone deacetylases - metabolism (1278) 1278
antineoplastic agents - pharmacology (1164) 1164
histones - metabolism (1124) 1124
pharmacology & pharmacy (1119) 1119
apoptosis - drug effects (1118) 1118
suberoylanilide hydroxamic acid (1058) 1058
histone deacetylase (987) 987
cell biology (962) 962
chemistry, medicinal (933) 933
hydroxamic acids - chemistry (914) 914
rats (845) 845
cell proliferation - drug effects (821) 821
histone deacetylase inhibitor (793) 793
gene expression (791) 791
dna methylation (701) 701
cells, cultured (698) 698
gene-expression (698) 698
proteins (686) 686
structure-activity relationship (671) 671
dose-response relationship, drug (665) 665
research (663) 663
cell line (620) 620
activation (608) 608
trichostatin a (580) 580
analysis (576) 576
chromatin (571) 571
azacitidine - pharmacology (541) 541
hydroxamic acids (539) 539
hydroxamic acids - therapeutic use (537) 537
tumor cells, cultured (530) 530
acetylation - drug effects (528) 528
in-vitro (528) 528
drug synergism (520) 520
cells (508) 508
vorinostat (508) 508
blotting, western (483) 483
epigenetics (482) 482
hydroxamic acids - chemical synthesis (481) 481
promoter regions, genetic (464) 464
hydroxamic acid (463) 463
transcription (463) 463
differentiation (457) 457
cell survival - drug effects (437) 437
hdac inhibitors (435) 435
gene expression regulation, neoplastic - drug effects (432) 432
inhibitors (428) 428
methylation (422) 422
azacitidine - analogs & derivatives (420) 420
research article (415) 415
reverse transcriptase polymerase chain reaction (415) 415
growth (406) 406
hydroxamic acids - administration & dosage (405) 405
rna, messenger - metabolism (400) 400
histones (393) 393
time factors (393) 393
trichostatin-a (388) 388
molecular structure (387) 387
in-vivo (373) 373
hematology (365) 365
valproic acid (360) 360
chemistry, organic (357) 357
genetic aspects (356) 356
multidisciplinary sciences (356) 356
genes (355) 355
cell cycle (348) 348
gene (348) 348
histone deacetylase inhibitors - therapeutic use (347) 347
inhibition (340) 340
indoles - pharmacology (339) 339
protease inhibitors - pharmacology (338) 338
antineoplastic agents - therapeutic use (333) 333
kinetics (331) 331
transfection (330) 330
mice, inbred c57bl (329) 329
phosphorylation (329) 329
down-regulation (326) 326
cell cycle - drug effects (325) 325
histone deacetylases - genetics (324) 324
physiological aspects (324) 324
middle aged (323) 323
signal transduction - drug effects (323) 323
histone acetylation (321) 321
rna, messenger - genetics (321) 321
care and treatment (320) 320
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (8255) 8255
Japanese (133) 133
Chinese (68) 68
German (46) 46
Russian (29) 29
French (24) 24
Dutch (8) 8
Italian (5) 5
Polish (4) 4
Portuguese (3) 3
Croatian (2) 2
Slovak (2) 2
Hungarian (1) 1
Romanian (1) 1
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Cellular and molecular life sciences : CMLS, ISSN 1420-9071, 2014, Volume 71, Issue 20, pp. 3885 - 3901
Histone deacetylases (HDACs) are a vast family of enzymes involved in chromatin remodeling and have crucial roles in numerous biological processes, largely... 
Life Sciences | Biochemistry, general | Life Sciences, general | Histone deacetylase inhibitor (HDACi) | Cell death | Autophagy | Biomedicine general | Cell Biology | Histone deacetylases (HDACs) | Apoptosis | HDAC INHIBITORS | SUBEROYLANILIDE HYDROXAMIC ACID | INDUCED APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | VALPROIC ACID | TRICHOSTATIN-A | CELL BIOLOGY | PHASE-II TRIAL | LYMPHOCYTIC-LEUKEMIA CELLS | HUMAN-MELANOMA CELLS | TNF-ALPHA | NF-KAPPA-B | Fatty Acids, Volatile - pharmacology | Humans | Histone Deacetylases - chemistry | Hydroxamic Acids - chemistry | Histone Deacetylases - metabolism | Peptides, Cyclic - pharmacology | Histone Deacetylase Inhibitors - chemistry | Peptides, Cyclic - chemistry | Neoplasms - drug therapy | Fatty Acids, Volatile - therapeutic use | Benzamides - therapeutic use | Signal Transduction - drug effects | Peptides, Cyclic - therapeutic use | Histone Deacetylase Inhibitors - pharmacology | Hydroxamic Acids - therapeutic use | Benzamides - pharmacology | Histone Deacetylase Inhibitors - therapeutic use | Cell Death - drug effects | Hydroxamic Acids - pharmacology | Fatty Acids, Volatile - chemistry | Benzamides - chemistry | Therapeutics | Histones | Cell differentiation | Gene expression | Homeopathy | Materia medica and therapeutics | Cells | Inhibitor drugs | apoptosis | autophagy | cell death
Journal Article
Blood, ISSN 1528-0020, 2012, Volume 119, Issue 11, pp. 2579 - 2589
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 08/2010, Volume 132, Issue 31, pp. 10842 - 10846
Journal Article
Cancer cell, ISSN 1535-6108, 05/2017, Volume 31, Issue 5, pp. 635 - 652.e6
Diffuse intrinsic pontine glioma (DIPG) is a fatal pediatric cancer with limited therapeutic options. The majority of cases of DIPG exhibit a mutation in... 
oligodendrocyte precursor cell | CDK7 | potassium channel | DIPG | EPH | super-enhancer | BRD4 | Receptors, Eph Family | Cell Proliferation | Humans | Gene Expression Regulation, Neoplastic | Drug Resistance, Neoplasm | Male | Brain Stem Neoplasms | Azepines | Journal Article | Research Support, N.I.H., Extramural | Dose-Response Relationship, Drug | Research Support, U.S. Gov't, Non-P.H.S | Pyrimidines | Transfection | RNA Interference | Time Factors | Triazoles | Histones | Female | Transcription, Genetic | Cyclin-Dependent Kinases | Indoles | Tumor Cells, Cultured | Signal Transduction | Antineoplastic Combined Chemotherapy Protocols | Chromatin Assembly and Disassembly | Mice, SCID | Hydroxamic Acids | Nuclear Proteins | Drug Synergism | Xenograft Model Antitumor Assays | Protein Kinase Inhibitors | Animals | Glioma | Phenylenediamines | Research Support, Non-U.S. Gov't | Mice, Inbred NOD | Histone Deacetylase Inhibitors | Transcription Factors | Mutation | Primary Cell Culture | THERAPEUTIC STRATEGY | SUPER-ENHANCERS | GENE | ONCOLOGY | CELL IDENTITY | K27M MUTATION | C-MYC | HISTONE H3.3 | BET BROMODOMAIN INHIBITION | MYC EXPRESSION | TUMOR-GROWTH | CELL BIOLOGY | Transcription, Genetic - drug effects | Cyclin-Dependent Kinases - metabolism | Brain Stem Neoplasms - drug therapy | Glioma - genetics | Glioma - pathology | Receptors, Eph Family - metabolism | Cyclin-Dependent Kinases - antagonists & inhibitors | Receptors, Eph Family - genetics | Pyrimidines - pharmacology | Signal Transduction - drug effects | Histone Deacetylase Inhibitors - pharmacology | Phenylenediamines - pharmacology | Histones - metabolism | Glioma - drug therapy | Brain Stem Neoplasms - pathology | Brain Stem Neoplasms - metabolism | Chromatin Assembly and Disassembly - drug effects | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Glioma - metabolism | Indoles - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Cyclin-Dependent Kinases - genetics | Nuclear Proteins - genetics | Hydroxamic Acids - pharmacology | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Transcription Factors - genetics | Azepines - pharmacology | Transcription Factors - metabolism | Triazoles - pharmacology | Brain Stem Neoplasms - genetics | Histones - genetics | Nuclear Proteins - antagonists & inhibitors | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Medical colleges | Gliomas | Developmental biology | Stem cells | Genetic aspects | Genetic transcription | Cell differentiation | Chromatin | Analysis | Potassium channels | Cells
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2002, Volume 99, Issue 5, pp. 2995 - 3000
Suberoylanilide hydroxamic acid (SAHA) is a hydroxamic acid-containing hybrid polar molecule... 
Biological Sciences | Messenger RNA | Antiinflammatories | Cytokines | Butyrates | Secretion | Cell lines | Histones | Mice | Macrophages | Tumors | CELLS | APOPTOSIS | ACTIVATION | ACETYLATION | INTERLEUKIN-1-BETA | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | BUTYRATE | INDUCTION | DIFFERENTIATION | TRICHOSTATIN-A | Leukocytes, Mononuclear - metabolism | Mitogens - pharmacology | Concanavalin A - pharmacology | Humans | Antineoplastic Agents - administration & dosage | RNA, Messenger - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Enzyme Inhibitors - administration & dosage | Liver - injuries | Liver - drug effects | Hydroxamic Acids - administration & dosage | Antineoplastic Agents - pharmacology | Tumor Cells, Cultured | Cytokines - genetics | Hydroxamic Acids - pharmacology | Macrophages, Peritoneal - drug effects | Hepatocytes - drug effects | Interleukin-12 - biosynthesis | Nitric Oxide - biosynthesis | Leukocytes, Mononuclear - drug effects | Cytokines - metabolism | Interferon-gamma - secretion | Tumor Necrosis Factor-alpha - secretion | Cells, Cultured | Enzyme Inhibitors - pharmacology | CD3 Complex - metabolism | Cell Division - drug effects | Tumor Necrosis Factor-alpha - pharmacology | Animals | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Lipopolysaccharides - pharmacology | Leukocytes, Mononuclear - cytology | Histone Deacetylase Inhibitors | Mice, Inbred BALB C | Macrophages, Peritoneal - metabolism | Interleukin-1 - secretion | Interferon-gamma - pharmacology | Usage | Immunocytochemistry | Physiological aspects | Inflammation | Research | Liver cells | lipopolysaccharides | suberoylanilide hydroxamic acid | histone deacetylase inhibitors
Journal Article
Journal Article
The Journal of pharmacology and experimental therapeutics, ISSN 0022-3565, 06/2007, Volume 321, Issue 3, pp. 892 - 901
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 03/2010, Volume 132, Issue 9, pp. 2868 - 2869
Journal Article
Journal Article
Molecules (Basel, Switzerland), ISSN 1420-3049, 2018, Volume 23, Issue 3, p. 566
A promising means in the search of new small molecules for the treatment of schistosomiasis (amongst other parasitic ailments) is by targeting the parasitic... 
Epigenetics | Virtual screening | Histone deacetylase (HDAC) inhibitors | Schistosomiasis | Docking | Crystal structure | PROTEIN | virtual screening | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | GLIDE | OXAMNIQUINE | CHEMISTRY, MULTIDISCIPLINARY | epigenetics | PRAZIQUANTEL | docking | ACCURATE DOCKING | crystal structure | RESISTANCE | GENERATION | histone deacetylase (HDAC) inhibitors | schistosomiasis | MOLECULAR-BASIS | PROGRAM | Apoptosis - drug effects | Zinc - metabolism | Helminth Proteins - chemistry | Anthelmintics - chemical synthesis | Crystallography, X-Ray | Structure-Activity Relationship | Zinc - chemistry | Schistosoma mansoni - genetics | Pyrrolidines - pharmacology | Histone Deacetylase Inhibitors - chemical synthesis | Protein Interaction Domains and Motifs | Schistosoma mansoni - growth & development | Binding Sites | Helminth Proteins - metabolism | Hydroxamic Acids - pharmacology | Schistosoma mansoni - drug effects | Gene Expression | Histone Deacetylases - genetics | Protein Structure, Secondary | Schistosoma mansoni - enzymology | Histone Deacetylases - chemistry | Histone Deacetylases - metabolism | Helminth Proteins - genetics | Chelating Agents - pharmacology | Animals | Pyrrolidines - chemical synthesis | Anthelmintics - pharmacology | Protein Binding | Histone Deacetylase Inhibitors - pharmacology | Molecular Docking Simulation | Chelating Agents - chemical synthesis | Hydroxamic Acids - chemical synthesis | Helminth Proteins - antagonists & inhibitors | Histone deacetylase | Screening | Chromatin | Inhibitors | Catalysis | In vitro methods and tests | Chelates | Zinc | Chelating Agents/pharmacology | Helminth Proteins/antagonists & inhibitors | Schistosoma mansoni/enzymology | Pyrrolidines/pharmacology | Life Sciences | Histone Deacetylases/genetics | Anthelmintics/chemical synthesis | Schistosoma mansoni/genetics | Helminth Proteins/genetics | Biomolecules | Histone Deacetylase Inhibitors/chemical synthesis | Chelating Agents/chemical synthesis | Pyrrolidines/chemical synthesis | Schistosoma mansoni/growth & development | Hydroxamic Acids/chemical synthesis | Zinc/chemistry | Biochemistry, Molecular Biology | Apoptosis/drug effects | Helminth Proteins/metabolism | Histone Deacetylases/chemistry | Hydroxamic Acids/pharmacology | Anthelmintics/pharmacology | Schistosoma mansoni/drug effects | Histone Deacetylases/metabolism | Helminth Proteins/chemistry | Histone Deacetylase Inhibitors/pharmacology | Zinc/metabolism
Journal Article