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index medicus (1473) 1473
animals (906) 906
humans (798) 798
hydroxyeicosatetraenoic acids - biosynthesis (689) 689
arachidonic acid (423) 423
male (418) 418
hydroxyeicosatetraenoic acids - metabolism (370) 370
rats (359) 359
biochemistry & molecular biology (329) 329
arachidonic acids - metabolism (311) 311
12-hydroxy-5,8,10,14-eicosatetraenoic acid (290) 290
hydroxyeicosatetraenoic acids - pharmacology (276) 276
arachidonic-acid (264) 264
chromatography, high pressure liquid (253) 253
female (230) 230
arachidonic acid - metabolism (224) 224
in vitro techniques (217) 217
cells, cultured (212) 212
mice (211) 211
calcimycin - pharmacology (189) 189
leukotriene b4 - biosynthesis (182) 182
lipoxygenase - metabolism (181) 181
lipoxins (159) 159
lipoxygenase (153) 153
neutrophils - metabolism (139) 139
abridged index medicus (131) 131
pharmacology & pharmacy (126) 126
cell biology (119) 119
neutrophils - drug effects (118) 118
kinetics (113) 113
leukotrienes (113) 113
biosynthesis (112) 112
rabbits (110) 110
hydroxyeicosatetraenoic acids (107) 107
blood platelets - metabolism (105) 105
prostaglandin-endoperoxide synthases - metabolism (104) 104
dose-response relationship, drug (97) 97
eicosanoids (97) 97
endocrinology & metabolism (97) 97
inflammation (96) 96
lipoxygenase inhibitors (93) 93
adult (92) 92
arachidonate 5-lipoxygenase - metabolism (92) 92
metabolism (92) 92
expression (91) 91
hydroxyeicosatetraenoic acids - blood (89) 89
physiology (89) 89
inhibition (87) 87
cytochrome p-450 enzyme system - metabolism (85) 85
metabolites (85) 85
prostaglandins - biosynthesis (83) 83
rats, inbred strains (83) 83
rats, sprague-dawley (81) 81
arachidonic acids - pharmacology (80) 80
cell line (78) 78
lipoxygenase inhibitors - pharmacology (76) 76
indomethacin - pharmacology (75) 75
biophysics (72) 72
stereoisomerism (72) 72
5-lipoxygenase (71) 71
blood platelets - drug effects (71) 71
hydroxyeicosatetraenoic acids - physiology (71) 71
cells (70) 70
physiological aspects (70) 70
immunology (68) 68
middle aged (68) 68
thromboxane b2 - biosynthesis (67) 67
aspirin - pharmacology (66) 66
leukotrienes - biosynthesis (65) 65
gas chromatography-mass spectrometry (64) 64
mass spectrometry (64) 64
prostaglandins (62) 62
cyclooxygenase (60) 60
cattle (59) 59
eicosanoids - biosynthesis (59) 59
macrophages - metabolism (59) 59
time factors (59) 59
20-hydroxyeicosatetraenoic acid (58) 58
anti-inflammatory agents, non-steroidal - pharmacology (57) 57
arachidonic acids - biosynthesis (57) 57
hypertension (57) 57
lipids (57) 57
tumor cells, cultured (57) 57
12-hydroxyeicosatetraenoic acid (56) 56
enzyme inhibitors - pharmacology (56) 56
arachidonate 12-lipoxygenase - metabolism (55) 55
arachidonate 15-lipoxygenase - metabolism (55) 55
hydroxyeicosatetraenoic acids - analysis (55) 55
peripheral vascular disease (55) 55
cyclooxygenase inhibitors - pharmacology (54) 54
dinoprostone - biosynthesis (54) 54
leukocytes - metabolism (52) 52
srs-a - biosynthesis (52) 52
20-hete (51) 51
activation (49) 49
endothelium, vascular - metabolism (49) 49
leukotriene b4 - metabolism (49) 49
oxidation-reduction (49) 49
arachidonic acids - blood (48) 48
leukotrienes - metabolism (48) 48
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Journal Article
Nature, ISSN 0028-0836, 2014, Volume 508, Issue 1, pp. 55 - 60
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 12/2017, Volume 57, Issue 6, pp. 692 - 701
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 09/2016, Volume 478, Issue 3, pp. 1338 - 1343
Journal Article
Journal of Cerebral Blood Flow & Metabolism, ISSN 0271-678X, 11/2013, Volume 33, Issue 11, pp. 1732 - 1742
Journal Article
Blood, ISSN 0006-4971, 02/2011, Volume 117, Issue 6, pp. 2033 - 2043
Journal Article
The Journal of Immunology, ISSN 0022-1767, 12/2003, Volume 171, Issue 12, pp. 6856 - 6865
Journal Article
Biochemical Journal, ISSN 0264-6021, 04/2007, Volume 403, Issue 1, pp. 109 - 118
AA (arachidonic acid) hydroxylation to 20-HETE (20-hydroxy-eicosatetraenoic acid) influences renal vascular and tubular function. To identify the CYP... 
Hydroxyeicosatetraenoic acid (HETE) | Gender | Arachidonic acid | Mouse kidney | Eicosapentaenoic acid | Cytochrome P450 | arachidonic acid | CYTOCHROME-P450 | gender | hydroxyeicosatetraenoic acid (HETE) | ENDOTHELIAL DYSFUNCTION | DEOXYCORTICOSTERONE ACETATE-SALT | BIOCHEMISTRY & MOLECULAR BIOLOGY | FATTY-ACIDS | cytochrome P450 | ARACHIDONIC-ACID | mouse kidney | eicosapentaenoic acid | METABOLISM | CARDIOVASCULAR-DISEASE | HUMAN CYP1A1 | HYPERTENSION | Species Specificity | Isoenzymes - genetics | Kidney - enzymology | Molecular Sequence Data | Male | DNA Primers | RNA - genetics | Gene Expression Regulation, Enzymologic | Fatty Acids, Nonesterified - metabolism | Hydroxyeicosatetraenoic Acids - biosynthesis | RNA - isolation & purification | Animals | Base Sequence | Cloning, Molecular | Cytochrome P450 Family 4 | Cytochrome P-450 Enzyme System - genetics | Female | Mice | Index Medicus | EET, epoxyeicosatrienoic acid | DHT, dihydrotestosterone | OH-LA, hydroxy LA | HETE, hydroxyeicosatetraenoic acid | EETeTr, epoxyeicosatetraenoic acid | cytb5, cytochrome b5 | DTT, dithiothreitol | DDDA, dodecan-1,12-dioic acid | HEPE, hydroxyeicosapentaenoic acid | RT, reverse transcriptase | 20-COOH-AA, eicosatetraen-1,20-dioic acid | PUFA, polyunsaturated fatty acid | CYP, cytochrome P450 | EPA, eicosapentaenoic acid | BK channel, calcium-activated potassium channel | Ang II, angiotensin II | LA, lauric acid | AA, arachidonic acid | RP-HPLC, reverse-phase HPLC | CPR, NADPH-CYP reductase | DOCA, deoxycorticosterone acetate | NP-HPLC, normal-phase HPLC
Journal Article
Annals of Neurology, ISSN 0364-5134, 01/2011, Volume 69, Issue 1, pp. 34 - 46
Objective: The 5-lipoxygenase (5-LO) enzymatic pathway is widely distributed within the central nervous system, and is upregulated in Alzheimer's disease.... 
OXIDATIVE STRESS | GENE | ALZHEIMERS-DISEASE | INVOLVEMENT | PRECURSOR PROTEIN-METABOLISM | GAMMA-SECRETASE | TRANSCRIPTIONAL REGULATION | EXPRESSION | NEUROSCIENCES | CLINICAL NEUROLOGY | INTRACELLULAR DOMAIN | PRESENILIN-1 | Central Nervous System - metabolism | Humans | Amyloid beta-Peptides - drug effects | Neuroblastoma | Immunoblotting - methods | Hydroxyeicosatetraenoic Acids - biosynthesis | Transfection | Linoleic Acids | Amyloid beta-Peptides - metabolism | Amyloid beta-Protein Precursor - metabolism | Female | Tumor Cells, Cultured | Amyloid beta-Peptides - biosynthesis | Leukotrienes - biosynthesis | Chemotactic Factors | Alzheimer Disease - enzymology | Enzyme Activation - drug effects | Immunoblotting - statistics & numerical data | Mutation - genetics | Transcription Factors - metabolism | Up-Regulation - drug effects | Amyloid Precursor Protein Secretases - metabolism | Arachidonate 5-Lipoxygenase - pharmacology | Hydroxyeicosatetraenoic Acids - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Amyloid Precursor Protein Secretases - drug effects | Alzheimer Disease - metabolism | Cyclic AMP Response Element-Binding Protein - metabolism | Lipoxygenase Inhibitors - metabolism | Mice | Alzheimer Disease - genetics | Lipoxygenase Inhibitors - pharmacology | Alzheimers disease | Kinases | Rodents | Index Medicus
Journal Article
The Journal of Immunology, ISSN 0022-1767, 11/2008, Volume 181, Issue 9, pp. 6514 - 6524
The peritoneal macrophage (M(P) is the site of greatest 12/15-lipoxygenase (12/15-LOX) expression in the mouse; however, its immunoregulatory role in this... 
DENDRITIC CELLS | RESOLUTION | RESOLVIN-E1 | ATHEROSCLEROSIS | RECEPTOR | INTERLEUKIN-12 | PERITONEAL-MACROPHAGES | 15-LIPOXYGENASE | IMMUNOLOGY | E-DEFICIENT MICE | EXPRESSION | Arachidonate 15-Lipoxygenase - biosynthesis | Staphylococcal Infections - pathology | Staphylococcus epidermidis - immunology | Macrophages, Peritoneal - pathology | Cytokines - physiology | Hydroxyeicosatetraenoic Acids - biosynthesis | Peritonitis - microbiology | Arachidonate 15-Lipoxygenase - deficiency | Inflammation Mediators - metabolism | Inflammation Mediators - physiology | 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid - biosynthesis | Arachidonate 12-Lipoxygenase - deficiency | Hydroxyeicosatetraenoic Acids - physiology | Acute Disease | Cytokines - metabolism | Staphylococcal Infections - immunology | Mice, Inbred C57BL | Cells, Cultured | Macrophages, Peritoneal - enzymology | Immunophenotyping | Arachidonate 12-Lipoxygenase - physiology | Peritonitis - immunology | Staphylococcal Infections - enzymology | Staphylococcus epidermidis - metabolism | Mice, Knockout | Arachidonate 12-Lipoxygenase - biosynthesis | 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid - physiology | Peritonitis - enzymology | Animals | Macrophages, Peritoneal - microbiology | Arachidonate 15-Lipoxygenase - physiology | Mice | Cytokines - biosynthesis | Index Medicus | Abridged Index Medicus
Journal Article
Prostaglandins, Leukotrienes and Essential Fatty Acids, ISSN 0952-3278, 2012, Volume 87, Issue 1, pp. 43 - 48
Journal Article
Hypertension, ISSN 0194-911X, 07/2007, Volume 50, Issue 1, pp. 123 - 129
Journal Article