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Philosophical transactions. Biological sciences, ISSN 1471-2970, 2013, Volume 368, Issue 1612, p. 20120432
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 03/2014, Volume 383, Issue 1-2, pp. 111 - 117
Journal Article
Journal of lipid research, ISSN 1539-7262, 2009, Volume 50, Issue 6, pp. 1090 - 1100
The role of farnesoid X receptor (FXR) in the development of atherosclerosis has been unclear. Here, LDL receptor (LDLR-/-) or apolipoprotein E (apoE(-/-))... 
Cholesterol 7α-hydroxylase | Sterol 12 α-hydroxylase | Atherosclerosis | Small heterodimer partner | atherosclerosis | TRIGLYCERIDE LEVELS | TRANSGENIC EXPRESSION | NEGATIVE FEEDBACK-REGULATION | NUCLEAR RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BILE-ACID SYNTHESIS | ESTROGEN-RECEPTOR | DENSITY-LIPOPROTEIN CHOLESTEROL | cholesterol 7 alpha-hydroxylase | NONFASTING TRIGLYCERIDES | small heterodimer partner | E-DEFICIENT MICE | sterol 12 alpha-hydroxylase | Dyslipidemias - genetics | Apolipoproteins E - deficiency | Gene Expression - drug effects | Steroid 12-alpha-Hydroxylase - antagonists & inhibitors | Receptors, Cytoplasmic and Nuclear - deficiency | Atherosclerosis - genetics | Male | Lipids - blood | Receptors, LDL - deficiency | Dyslipidemias - prevention & control | Female | Indoles - pharmacology | Receptors, LDL - genetics | Atherosclerosis - pathology | Mice, Inbred C57BL | Bile Acids and Salts - metabolism | Receptors, Cytoplasmic and Nuclear - agonists | Receptors, Cytoplasmic and Nuclear - genetics | Atherosclerosis - metabolism | Mice, Knockout | Azepines - pharmacology | Cholesterol 7-alpha-Hydroxylase - genetics | Steroid 12-alpha-Hydroxylase - genetics | Animals | Apolipoproteins E - genetics | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Dyslipidemias - metabolism | Mice | Cholesterol 7-alpha-Hydroxylase - antagonists & inhibitors | Atherosclerosis - prevention & control | Receptors, Cytoplasmic and Nuclear - metabolism | sterol 12 α-hydroxylase | cholesterol 7α-hydroxylase
Journal Article
Critical Reviews in Biochemistry and Molecular Biology, ISSN 1549-7798, 2008, Volume 39, Issue 1, pp. 21 - 68
Journal Article
Brain Research, ISSN 0006-8993, 2011, Volume 1373, pp. 240 - 252
Journal Article
Molecular and cellular biology, ISSN 0270-7306, 2007, Volume 27, Issue 23, pp. 8330 - 8339
Journal Article
Best Practice & Research: Clinical Endocrinology & Metabolism, ISSN 1521-690X, 2011, Volume 25, Issue 4, pp. 531 - 541
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2007, Volume 104, Issue 40, pp. 15665 - 15670
Coordinated regulation of bile acid biosynthesis, the predominant pathway for hepatic cholesterol catabolism, is mediated by few key nuclear receptors... 
Hep G2 cells | Receptors | Messenger RNA | Bile acids | Hepatocytes | Small interfering RNA | Gene expression regulation | Biosynthesis | Promoter regions | Repression | Farnesoid X receptor | Sterol 12α hydroxylase | Cholesterol 7α hydroxylase | Small heterodimer partner | FXR | farnesoid X receptor | NEGATIVE FEEDBACK-REGULATION | MULTIDISCIPLINARY SCIENCES | IDENTIFICATION | ORPHAN NUCLEAR RECEPTOR | cholesterol 7 alpha hydroxylase | RESPONSE ELEMENT | REPRESSION | LIGANDS | sterol 12 alpha hydroxylase | LIVER | small heterodimer partner | SHP | HETERODIMER PARTNER | Steroid 12-alpha-Hydroxylase - metabolism | Promoter Regions, Genetic | Humans | Bile Acids and Salts - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Receptors, Cytoplasmic and Nuclear - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Liver Neoplasms | DNA-Binding Proteins - metabolism | Gene Expression Regulation, Enzymologic | Transcription Factors - metabolism | Cholesterol 7-alpha-Hydroxylase - genetics | Steroid 12-alpha-Hydroxylase - genetics | Cholesterol 7-alpha-Hydroxylase - metabolism | Cell Line, Tumor | Transcription, Genetic | Carcinoma, Hepatocellular | Receptors, Cytoplasmic and Nuclear - metabolism | Research | Genetic transcription | Hydroxylases | Properties | Observations | Biological Sciences | sterol 12α hydroxylase | cholesterol 7α hydroxylase
Journal Article
Journal Article
Journal of lipid research, ISSN 1539-7262, 2009, Volume 50, Issue 8, pp. 1509 - 1520
In the past, bile acids were considered to be just detergent molecules derived from cholesterol in the liver. They were known to be important for the... 
G protein coupled receptor TGR5 | Short heterodimer partner | Sterol 27-hydroxylase | Intestine | Cholesterol 7α-Hydroxylase | Sterol 12α-Hydroxylase | Secondary bile acids | Steroidogenic acute regulatory protein | Muscarinic receptors | Fibroblast growth factor 15/19 | SMALL HETERODIMER PARTNER | PROTEIN-KINASE-C | intestine | sterol 27-hydroxylase | BIOCHEMISTRY & MOLECULAR BIOLOGY | ORPHAN NUCLEAR RECEPTOR | muscarinic receptors | secondary bile acids | GROWTH-FACTOR RECEPTOR | cholesterol 7 alpha-hydroxylase | ORGANIC SOLUTE TRANSPORTER | short heterodimer partner | fibroblast growth factor 15/19 | ALPHA-OST-BETA | PRIMARY RODENT HEPATOCYTES | FARNESOID-X-RECEPTOR | CHOLESTEROL 7-ALPHA-HYDROXYLASE GENE | steroidogenic acute regulatory protein | PRIMARY RAT HEPATOCYTES | sterol 12 alpha-hydroxylase | Bile Acids and Salts - biosynthesis | Liver - enzymology | Receptors, G-Protein-Coupled - metabolism | Signal Transduction | Bile - chemistry | Humans | Liver - metabolism | Bile - physiology | Fibroblast Growth Factors - genetics | Receptors, G-Protein-Coupled - agonists | Digestion - physiology | Fibroblast Growth Factors - metabolism | Animals | Gastrointestinal Tract - physiology | Bile Acids and Salts - physiology | Enterohepatic Circulation - physiology | Receptors, Cytoplasmic and Nuclear - metabolism | Thematic Review | cholesterol 7α-hydroxylase | sterol 12α-hydroxylase | fibroblast growth factor 15
Journal Article