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Nature Cell Biology, ISSN 1465-7392, 2014, Volume 16, Issue 4, pp. 357 - 366
The YAP and TAZ mediators of the Hippo pathway ( hereafter called YAP/TAZ) promote tissue proliferation and organ growth. However, how their biological... 
ORGAN GROWTH | CHOLESTEROL | YAP/TAZ | TRANSCRIPTION | HIPPO PATHWAY | STATINS | CELL BIOLOGY | Phosphorylation - physiology | Cell Proliferation | Active Transport, Cell Nucleus - physiology | Humans | Intracellular Signaling Peptides and Proteins - metabolism | Drosophila Proteins - metabolism | Phosphoproteins - metabolism | Sterol Regulatory Element Binding Proteins - genetics | Breast Neoplasms - metabolism | Drosophila melanogaster - metabolism | RNA Interference | Tumor Suppressor Proteins - genetics | HEK293 Cells | Trans-Activators - genetics | Female | Transcription, Genetic | Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent - metabolism | Nuclear Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Signal Transduction | HCT116 Cells | Protein-Serine-Threonine Kinases - genetics | Nuclear Proteins - metabolism | Sterol Regulatory Element Binding Proteins - metabolism | Transcription Factors - genetics | Mevalonic Acid - metabolism | Polyisoprenyl Phosphates - metabolism | Transcription Factors - metabolism | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | rho GTP-Binding Proteins - metabolism | Trans-Activators - metabolism | Mice | Polyisoprenyl Phosphates - biosynthesis | Pyridines - pharmacology | RNA, Small Interfering | Drosophila Proteins - genetics | Adaptor Proteins, Signal Transducing - metabolism | Cell metabolism | Genetic research | Genetic aspects | Research | Cellular control mechanisms | Index Medicus
Journal Article
Metabolic Engineering, ISSN 1096-7176, 2011, Volume 13, Issue 5, pp. 588 - 597
Expression of foreign pathways often results in suboptimal performance due to unintended factors such as introduction of toxic metabolites, cofactor imbalances... 
Mevalonate kinase | Metabolic pathway optimization | Cofactor regeneration | E. coli | Mevalonate pathway | HMG-CoA Reductase | COENZYME-A REDUCTASE | 3-HYDROXY-3-METHYLGLUTARYL-COA REDUCTASE | ADHE GENE | ESCHERICHIA-COLI | ENZYME INFORMATION-SYSTEM | NAD | BRENDA | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOSYNTHESIS | ANAEROBIC REGULATION | PURIFICATION | Candida - genetics | Fungal Proteins - biosynthesis | Sesquiterpenes - metabolism | Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent - genetics | Bacterial Proteins - genetics | Phosphotransferases (Alcohol Group Acceptor) - genetics | Candida - enzymology | Organisms, Genetically Modified - growth & development | Fungal Proteins - genetics | Mevalonic Acid - metabolism | Formate Dehydrogenases - genetics | Formate Dehydrogenases - biosynthesis | Delftia acidovorans - genetics | Escherichia coli - genetics | Formates - pharmacology | Escherichia coli - metabolism | Organisms, Genetically Modified - metabolism | Bacterial Proteins - biosynthesis | Delftia acidovorans - enzymology | Escherichia coli - growth & development | Organisms, Genetically Modified - genetics | Formates - metabolism | Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent - biosynthesis | Phosphotransferases (Alcohol Group Acceptor) - biosynthesis | Enzymes | Metabolites | Biomass energy | Analysis | Escherichia coli | Index Medicus
Journal Article
Journal Article
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 2016, Volume 78, pp. 177 - 184
Journal Article
Immunology, ISSN 0019-2805, 11/2017, Volume 152, Issue 3, pp. 484 - 493
Journal Article
Cancer Genetics, ISSN 2210-7762, 2015, Volume 208, Issue 5, pp. 241 - 252
The mevalonate pathway provides metabolites for post-translational modifications such as farnesylation, which are critical for the activity of RAS downstream... 
Hematology, Oncology and Palliative Medicine | Medical Education | cancer metabolism | bisphosphonates | statins | epigenetics | Mevalonate pathway | Epigenetics | Cancer metabolism | Bisphosphonates | Statins | COA REDUCTASE INHIBITOR | VITAMIN-D | MORPHOGENETIC PROTEIN PATHWAY | HISTONE DEACETYLASE ACTIVITY | BREAST-CANCER | IN-VITRO | ONCOLOGY | BISPHOSPHONATE ZOLEDRONIC ACID | COLORECTAL-CANCER | PROSTATE-CANCER | GENETICS & HEREDITY | FATTY-ACID SYNTHASE | Neoplasms - metabolism | Lovastatin - pharmacology | DNA (Cytosine-5-)-Methyltransferase 1 | Down-Regulation | Humans | Mevalonic Acid - metabolism | Simvastatin - pharmacology | Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent - metabolism | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Neoplasms - genetics | Protein Processing, Post-Translational - drug effects | Cell Line, Tumor | Mevalonic Acid - antagonists & inhibitors | Female | Vitamin D - metabolism | Antineoplastic Agents - pharmacology | Epigenesis, Genetic - drug effects | MicroRNAs - genetics | NADP - metabolism | Diphosphonates - pharmacology | DNA (Cytosine-5-)-Methyltransferases - biosynthesis | Fatty Acids - biosynthesis | Epigenetic inheritance | Medical colleges | Simvastatin | Transferases | Calcifediol | Fatty acids | MicroRNA | Synthesis | Metabolites | Vitamin D | Analysis | Cancer cells | Physiological aspects | Alfacalcidol | Cancer | Index Medicus | Contributions to Progress and Promise of Epigenetics for Diagnosis and Therapy in Cancer
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 2011, Volume 81, Issue 8, pp. 1054 - 1064
Journal Article
Metabolic Engineering, ISSN 1096-7176, 2009, Volume 11, Issue 6, pp. 328 - 334
Journal Article